Designing the new
We design novel proteins using structure-aware AI/optimization models. Our designed proteins find application in energy, environment, therapeutics, and critical ionic separations.
We are located within the Nanovaccine Institute and affiliated to the Chemical & Biological Engineering department at Iowa State.
▲ Engineering rationale for protein pores
Protein pores act as nature's sieves, sorting molecules and ions. We can tailor these pores for targeted separations.
Cell Systems
▲ AI-guided protein structure prediction
RGN2 protein language model folds orphan and designed proteins, surpassing AlphaFold2 in efficiency.
Nature Biotech Nature News
▲ Design protein pores
Protein pores act as nature's sieves, sorting molecules and ions. We can tailor these pores for targeted separations.
Nature Communications
