organism: Arabidopsis thaliana

substrate_name: thioredoxin


enzyme_display_name: thioredoxin-disulfide reductase (NADPH)

organism: Deinococcus radiophilus

substrate_name: NADPH

source_db: brenda

kcat_display: Not reported

ki_display: Not reported

kcat_over_km_display: Not reported

mutation_signature: Unknown

source_license: CC BY 4.0

km_unit: mM


organism: Leptospira interrogans serovar Copenhageni

source_db: oed

protein_accession_database: UniProt


organism: Plasmodium falciparum (isolate FCH-5)

substrate_name: NADPH (at 20 degrees Celsius and pH 7.4)

source_db: uniprot


organism: Taenia crassiceps

substrate_name: GSSG


enzyme_display_name: sulfite dehydrogenase (cytochrome)

organism: Starkeya novella

substrate_name: sulfite


organism: Thermotoga maritima

substrate_name: benzyl viologen


enzyme_display_name: thiosulfate dehydrogenase

organism: Pseudomonas sp.

substrate_name: thiosulfate


enzyme_display_name: thiol oxidase

organism: Aspergillus oryzae


enzyme_display_name: sulfide-cytochrome-c reductase (flavocytochrome c)

organism: Allochromatium vinosum

substrate_name: Sulfide


organism: Sus scrofa

substrate_name: N-acetylcysteine


substrate_name: D-Cys


enzyme_display_name: methanethiol oxidase

organism: Hyphomicrobium sp.


enzyme_display_name: prenylcysteine oxidase


enzyme_display_name: formylglycine-generating enzyme

organism: Thermomonospora curvata


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: 5'-adenylyl sulfate (at pH 8.5 and 30 degrees Celsius)


enzyme_display_name: glutathione oxidase


enzyme_display_name: L-methionine (S)-S-oxide reductase

organism: Escherichia coli B

substrate_name: L-methionine (S)-S-oxide


enzyme_display_name: L-methionine (R)-S-oxide reductase

organism: Escherichia coli

substrate_name: L-Methionine (R)-S-oxide; Reduced thioredoxin

kcat_over_km_origin: calculated

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Escherichia coli (strain K12)

substrate_name: L-methionine-(R)-S-oxide


organism: Saccharomyces cerevisiae

substrate_name: Reduced thioredoxin; L-Methionine (R)-S-oxide

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)


organism: Mus musculus

substrate_name: H2O; O2; Methanethiol


organism: Thermoplasma acidophilum

substrate_name: L-methionine (R)-S-oxide

source_db: skid

source_license: CC BY-NC-ND 4.0


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: 3-HSA (with FAD at pH 7 and at 25 degrees Celsius)


enzyme_display_name: glutathione dehydrogenase (ascorbate)

organism: Homo sapiens

substrate_name: dehydroascorbate

verification_status: verified


enzyme_display_name: respiratory dimethylsulfoxide reductase

substrate_name: 2-mercaptopyridine N-oxide


substrate_name: 2-chloropyridine N-oxide (at pH 5 and at 30 degrees Celsius)


enzyme_display_name: glutathionyl-hydroquinone reductase

organism: Sphingobium chlorophenolicum


substrate_name: glutathione

source_license: CC BY 4.0; CC BY-NC-ND 4.0


enzyme_display_name: assimilatory sulfite reductase (ferredoxin)

organism: Limnospira platensis

substrate_name: S-Sulfoglutathione


enzyme_display_name: chlorate reductase

organism: Haloferax mediterranei

substrate_name: Chlorate


enzyme_display_name: sulfiredoxin

substrate_name: ATP


organism: Stutzerimonas chloritidismutans


enzyme_display_name: nitrate reductase (cytochrome)

organism: Cereibacter sphaeroides f. sp. denitrificans

substrate_name: nitrate


enzyme_display_name: homocysteine S-methyltransferase

organism: Arabidopsis thaliana

substrate_name: S-methylmethionine


verification_status: unverified


substrate_name: L-homocysteine


organism: Brassica oleracea var. italica

substrate_name: DL-homocysteine


enzyme_display_name: phosphoethanolamine N-methyltransferase

organism: Plasmodium vivax

substrate_name: Ethanolamine phosphate


enzyme_display_name: caffeoyl-CoA O-methyltransferase

organism: Petroselinum crispum

substrate_name: caffeoyl-CoA


organism: Pyrus x bretschneideri


organism: Triticum aestivum

substrate_name: S-Adenosyl-L-methionine; Caffeoyl-CoA

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


organism: Vanilla planifolia

substrate_name: tricetin


enzyme_display_name: tryptophan 2-C-methyltransferase

organism: Kitasatospora setae

substrate_name: L-tryptophan

km_display: Not reported


enzyme_display_name: eukaryotic sulfide quinone oxidoreductase

substrate_name: sulfide (with sulfite as electron acceptor)


organism: Pseudomonas denitrificans


organism: Methanobacterium ivanovii


organism: Aspergillus parasiticus

substrate_name: dihydrodemethylsterigmatocystin


organism: Pseudomonas denitrificans (nom. rej.)

substrate_name: uroporphyrinogen III


enzyme_display_name: alcohol dehydrogenase

organism: Homo sapiens

substrate_name: all-trans-Retinal


enzyme_display_name: sterigmatocystin 8-O-methyltransferase

substrate_name: sterigmatocystin


organism: Thalictrum flavum

substrate_name: (R,S)-Norreticuline


substrate_name: S-Adenosyl-L-methionine


enzyme_display_name: (S)-scoulerine 9-O-methyltransferase

organism: Coptis japonica

substrate_name: (S)-scoulerine


enzyme_display_name: methionine S-methyltransferase

organism: Wollastonia biflora

substrate_name: L-Met


substrate_name: S-Adenosyl-L-methionine; (S)-Scoulerine


organism: Eschscholzia californica


enzyme_display_name: methionine synthase

organism: Escherichia coli

substrate_name: S-adenosyl-L-methionine


substrate_name: (S)-Stylopine


substrate_name: (R,S)-stylopine


organism: Dehalococcoides mccartyi

substrate_name: L-homocysteine


organism: Rattus norvegicus


organism: Thermus thermophilus


organism: Sus scrofa

ki_unit: mM


organism: Papaver bracteatum

substrate_name: (R,S)-Stylopine


organism: Papaver somniferum


enzyme_display_name: chlorophenol O-methyltransferase

organism: Trichoderma longibrachiatum

substrate_name: 2,4,6-trichlorophenol (2,4,6-TCP)


enzyme_display_name: arsenite methyltransferase

substrate_name: S-Adenosyl-L-methionine; Arsenite


substrate_name: sodium arsenite


enzyme_display_name: (S)-coclaurine-N-methyltransferase

organism: Stephania intermedia

substrate_name: (R)-coclaurine


enzyme_display_name: columbamine O-methyltransferase

substrate_name: S-Adenosyl-L-methionine; Columbamine


enzyme_display_name: jasmonate O-methyltransferase

organism: Arabidopsis thaliana


substrate_name: (RS)-coclaurine


organism: Brassica rapa subsp. oleifera

substrate_name: jasmonate


substrate_name: (-)-Jasmonic acid


organism: Thalictrum flavum subsp. glaucum

substrate_name: (R,S)-norreticuline


organism: Humulus lupulus

substrate_name: chalconaringenin


organism: Medicago sativa

substrate_name: isoliquiritigenin


organism: Aphanothece halophytica

substrate_name: S-adenosyl-L-homocysteine (at pH 8.8 and at 37 degrees Celsius)


enzyme_display_name: glycine/sarcosine N-methyltransferase

organism: Halorhodospira halochloris

substrate_name: sarcosine (at pH 7.4 and at 37 degrees Celsius)


enzyme_display_name: theobromine synthase

organism: Coffea arabica


organism: Camellia ptilophylla

substrate_name: 7-methylxanthine (in the presence of 50 uM S-adenosyl-L-methionine)


organism: Camellia irrawadiensis


organism: Parasynechococcus marenigrum (strain WH8102)

substrate_name: AdoMet (with glycine at pH 8.2 and at 37 degrees Celsius)


organism: Theobroma cacao


substrate_name: AdoMet (with dimethylglycine at pH 7.4 and at 37 degrees Celsius)


enzyme_display_name: caffeine synthase

organism: Camellia sinensis


substrate_name: 7-methylxanthine for the recombinant protein


substrate_name: paraxanthine


enzyme_display_name: tricin synthase

organism: Oryza sativa subsp. japonica

substrate_name: tricetin


organism: Oryza sativa

substrate_name: S-Adenosyl-L-methionine; Tricetin


organism: Zea mays


organism: Bacillus subtilis

substrate_name: S-adenosyl-L-methionine


enzyme_display_name: carnosine N-methyltransferase

organism: Gallus gallus

substrate_name: carnosine


organism: Saccharomyces cerevisiae

substrate_name: S-Adenosyl-L-methionine; Carnosine


organism: Methanocaldococcus jannaschii

substrate_name: S-Adenosyl-L-methionine; tRNA guanine


organism: Streptomyces azureus


enzyme_display_name: mycinamicin VI 2''-O-methyltransferase

organism: Micromonospora griseorubida

substrate_name: mycinamicin VI


enzyme_display_name: flavonoid 4'-O-methyltransferase

organism: Artemisia annua

substrate_name: kaempferol


enzyme_display_name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M

organism: Methanosarcina barkeri


organism: Methanosarcina barkeri (strain Fusaro / DSM 804)

substrate_name: dimethylamine


enzyme_display_name: mycinamicin III 3''-O-methyltransferase

substrate_name: mycinamicin III


enzyme_display_name: salicylate carboxymethyltransferase

organism: Clarkia breweri

substrate_name: salicylate


organism: Pisum sativum


enzyme_display_name: phenylethanolamine N-methyltransferase

organism: Macaca mulatta

substrate_name: normetanephrine


enzyme_display_name: selenocysteine Se-methyltransferase

organism: Astragalus bisulcatus


enzyme_display_name: phenylpyruvate C(3)-methyltransferase

organism: Streptomyces hygroscopicus


enzyme_display_name: emodin O-methyltransferase

organism: Aspergillus terreus

substrate_name: emodin


enzyme_display_name: trans-anol O-methyltransferase

organism: Acorus calamus

substrate_name: resveratrol


organism: Amycolatopsis mediterranei

substrate_name: 27-O-demethylrifamycin SV


enzyme_display_name: carminomycin 4-O-methyltransferase

organism: Streptomyces sp.

substrate_name: carminomycin


enzyme_display_name: mitomycin 6-O-methyltransferase

organism: Streptomyces lavendulae


organism: Saccharomyces cerevisiae


enzyme_display_name: type I protein arginine methyltransferase

organism: Homo sapiens

substrate_name: AdoMet


organism: Rattus norvegicus


organism: Sphingobium sp.

substrate_name: vanillate


enzyme_display_name: mRNA m(6)A methyltransferase


verification_status: corrected


organism: Mycobacterium abscessus


organism: Eubacterium limosum

substrate_name: L-carnitine


substrate_name: gamma-butyrobetaine


enzyme_display_name: norajmaline N-methyltransferase

organism: Rauvolfia serpentina

substrate_name: norajmaline


enzyme_display_name: ajmaline N-methyltransferase


enzyme_display_name: acetylserotonin O-methyltransferase

organism: Arabidopsis thaliana

substrate_name: N-acetylserotonin


organism: Bos taurus

substrate_name: S-adenosyl-L-methionine


organism: Oncorhynchus tshawytscha


enzyme_display_name: mycothione reductase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: NADPH


organism: Oryza sativa


enzyme_display_name: flavone 3'-O-methyltransferase

organism: Chrysosplenium americanum

substrate_name: quercetin


enzyme_display_name: Transferred entry: 2.1.1.354

substrate_name: S-Adenosyl-L-methionine


enzyme_display_name: thymidylate synthase

organism: Crithidia fasciculata


organism: Enterococcus faecalis

substrate_name: methylenetetrahydrofolate


organism: Lactobacillus casei

substrate_name: dUMP


enzyme_display_name: peroxidase

organism: Burkholderia pseudomallei


enzyme_display_name: sterol 24-C-methyltransferase

organism: Glycine max

substrate_name: Cycloartenol; S-Adenosyl-L-methionine


organism: Leishmania major


enzyme_display_name: isoflavone 4'-O-methyltransferase

organism: Glycyrrhiza echinata


organism: Pisum sativum


organism: Medicago truncatula


enzyme_display_name: indolepyruvate C-methyltransferase

organism: Streptomyces griseus

substrate_name: indolepyruvate (at 30 degrees Celsius and pH 7.6)


organism: Mus musculus

substrate_name: S-methyl-L-methionine


organism: Rattus norvegicus

substrate_name: L-homocysteine


organism: Sus scrofa


substrate_name: glycine betaine


enzyme_display_name: putrescine N-methyltransferase

organism: Datura stramonium


organism: Solanum lycopersicum

substrate_name: putrescine


enzyme_display_name: mRNA (guanine-N(7))-methyltransferase

organism: Encephalitozoon cuniculi (strain GB-M1)

substrate_name: GTP


organism: Saccharomyces cerevisiae

substrate_name: GpppA


enzyme_display_name: methyltransferase cap1

organism: Homo sapiens


organism: Orthopoxvirus vaccinia


enzyme_display_name: catechol O-methyltransferase

substrate_name: S-Adenosyl-L-methionine; L-Adrenaline


organism: Sus scrofa domesticus


enzyme_display_name: calmodulin-lysine N-methyltransferase


enzyme_display_name: nicotinate N-methyltransferase

substrate_name: nicotinate


organism: Aquilegia coerulea

substrate_name: S-Adenosyl-L-methionine; Nicotinate


substrate_name: Nicotinate; S-Adenosyl-L-methionine


organism: Theobroma cacao


organism: Bos taurus

substrate_name: S-adenosyl-L-methionine


organism: Arabidopsis thaliana


organism: Enterobacteria phage T4

substrate_name: S-adenosylmethionine


organism: Escherichia phage T1


organism: Pyrococcus horikoshii


organism: Enterococcus faecalis


organism: Pinus massoniana


organism: Caenorhabditis elegans


enzyme_display_name: histamine N-methyltransferase


organism: Cavia porcellus

substrate_name: histamine


organism: Mus musculus


organism: Rattus rattus

substrate_name: S-Adenosyl-L-methionine; Histamine


enzyme_display_name: apigenin 4'-O-methyltransferase

organism: Plagiochasma appendiculatum

substrate_name: apigenin


organism: Rattus norvegicus


organism: Papaver somniferum

substrate_name: (S)-scoulerine


organism: Coptis japonica


enzyme_display_name: thiol S-methyltransferase

organism: Phaeodactylum tricornutum

substrate_name: thiocyanate


organism: Homo sapiens

substrate_name: hydrogen sulfide


enzyme_display_name: aminomethyltransferase

organism: Gallus gallus

substrate_name: tetrahydrofolate


substrate_name: NAD+; Glycine; 5,6,7,8-Tetrahydrofolate


organism: Oryctolagus cuniculus


organism: Pisum sativum


organism: Canis familiaris


organism: Mycobacterium tuberculosis


enzyme_display_name: methionyl-tRNA formyltransferase

organism: Enterococcus faecalis


organism: Escherichia coli (strain K12)


enzyme_display_name: D-alanine 2-hydroxymethyltransferase

organism: Ensifer sp. AJ110404


organism: Streptomyces niveus

substrate_name: decarbamoylnovobiocin


enzyme_display_name: acetyl-CoA carboxytransferase

substrate_name: malonyl-CoA


enzyme_display_name: aspartate carbamoyltransferase

organism: Methanocaldococcus jannaschii

substrate_name: L-aspartate


organism: Pyrococcus abyssi

substrate_name: Carbamoyl phosphate


enzyme_display_name: ornithine carbamoyltransferase

organism: Bos taurus

substrate_name: ornithine


substrate_name: L-citrulline


substrate_name: Phosphate


substrate_name: Carbamoyl phosphate; L-Ornithine


substrate_name: L-Citrulline


substrate_name: L-Ornithine; Carbamoyl phosphate


substrate_name: L-Ornithine


organism: Mycoplasma arthritidis

substrate_name: L-Citrulline; Phosphate


organism: Pseudomonas aeruginosa


organism: Agrobacterium tumefaciens


organism: Pseudomonas syringae phaseolicola


enzyme_display_name: putrescine carbamoyltransferase

substrate_name: putrescine


organism: Sus scrofa


enzyme_display_name: transketolase

organism: Cyberlindnera jadinii

substrate_name: thiamine diphosphate


organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

substrate_name: fructose 6-phosphate (at pH 7.0 and 37 degrees Celsius)


organism: Homo sapiens

substrate_name: D-Ribose 5-phosphate; D-Xylulose 5-phosphate


organism: Leishmania mexicana


organism: Saccharomyces cerevisiae

substrate_name: D-Ribose 5-phosphate


organism: Rattus norvegicus


substrate_name: D-Xylulose 5-phosphate


organism: Rhodobacter sphaeroides


organism: Scheffersomyces stipitis


substrate_name: Hydroxypyruvate


substrate_name: sedoheptulose 7-phosphate


organism: Spinacia oleracea

substrate_name: D-ribose 5-phosphate


substrate_name: xylulose 5-phosphate


enzyme_display_name: ubiquinol oxidase (non-electrogenic)

organism: Arabidopsis thaliana


enzyme_display_name: lignostilbene alphabeta-dioxygenase

organism: Sphingomonas paucimobilis


enzyme_display_name: flavanone 3-dioxygenase

organism: Oryza sativa subsp. japonica

substrate_name: S-eriodictyol


enzyme_display_name: vinorine hydroxylase

organism: Rauvolfia serpentina

substrate_name: vinorine


enzyme_display_name: methyl farnesoate epoxidase

organism: Diploptera punctata

substrate_name: methyl (2E,6E)-farnesoate (with purified enzyme)


enzyme_display_name: (E)-2-methylbutanal oxime monooxygenase

organism: Manihot esculenta

substrate_name: (Z)-2-methylbutanal oxime


enzyme_display_name: methanethiol oxidase

substrate_name: methanethiol


organism: Hyphomicrobium sp


organism: Mus musculus


enzyme_display_name: sphingoid base N-palmitoyltransferase

substrate_name: sphinganine (d18:0)


substrate_name: sphinganine


enzyme_display_name: laccase

organism: Bacillus sp. SL-1

substrate_name: Syringaldazine; O2


organism: Bacteroides thetaiotaomicron


substrate_name: Syringaldazine


organism: Escherichia coli


organism: Fomitopsis pinicola

substrate_name: guaiacol


organism: basidiomycete PM1


organism: Lentinus brumalis


organism: Meiothermus ruber


organism: Caldalkalibacillus thermarum

substrate_name: O2; 2,6-Dimethoxyphenol


organism: Aquifex aeolicus


organism: Phoma sp.

substrate_name: syringaldazine


organism: Pseudomonas putida


enzyme_display_name: trans-4-coumaroyl-CoA 2'-hydroxylase

organism: Ipomoea batatas

substrate_name: feruloyl-CoA


organism: Ruta graveolens


enzyme_display_name: methylphosphonate hydroxylase

organism: Gimesia maris (strain ATCC 29201 / DSM 8797 / 534-30)

substrate_name: methylphosphonate


enzyme_display_name: methane monooxygenase (particulate)

organism: Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)

substrate_name: Unknown


enzyme_display_name: lupanine 17-hydroxylase (cytochrome c)

organism: Pseudomonas sp

substrate_name: sparteine (at 25 degrees Celsius and at pH 8.5)


enzyme_display_name: isopiperitenol dehydrogenase

organism: Mentha piperita

substrate_name: (-)-trans-carveol (at pH 7.5)


enzyme_display_name: tyramine N-methyltransferase

organism: Lophophora williamsii

substrate_name: mescaline


enzyme_display_name: trans-anol O-methyltransferase

organism: Pimpinella anisum

substrate_name: isoeugenol (at pH 7.5 and 25 degrees Celsius)


enzyme_display_name: phenylpyruvate C(3)-methyltransferase

organism: Streptomyces hygroscopicus

substrate_name: S-adenosyl-L-methionine


organism: Pyrobaculum aerophilum


organism: Streptomyces viridochromogenes


organism: Shiraia sp. SUPER-H168


organism: Streptomyces ipomoeae


organism: Streptomyces coelicolor


organism: Corynebacterium glutamicum


organism: Streptomyces sviceus


organism: Mus musculus


enzyme_display_name: sphingoid base N-stearoyltransferase


enzyme_display_name: RING-type E3 ubiquitin transferase

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: ATP


organism: Escherichia coli

substrate_name: UDP-Glc


enzyme_display_name: quinolinate synthase

organism: Bacillus subtilis (strain 168)

substrate_name: dihydroxyacetone phosphate


organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)


enzyme_display_name: pyridinol guanylyltransferase

organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: GTP


organism: Cricetulus griseus

substrate_name: L-serine


organism: Homo sapiens

substrate_name: serine (in the presence of 1 mM PE)


substrate_name: serine (in the presence of 2 mM PC)


enzyme_display_name: isoamyl acetate esterase

substrate_name: 3-methylbutyl acetate


enzyme_display_name: catechol oxidase

organism: Malus domestica

substrate_name: O2; Caffeoyl quinic acid


organism: Bacillus licheniformis


organism: Geobacter metallireducens


organism: Bacillus clausii


organism: Melanocarpus albomyces


organism: Halobacterium volcanii


organism: Meiothermus ruber


enzyme_display_name: deacetoxycephalosporin-C synthase

organism: Streptomyces clavuligerus

substrate_name: ampicillin


substrate_name: Ampicillin


substrate_name: Penicillin G


substrate_name: 2-Oxoglutarate; O2; Penicillin G


substrate_name: penicillin G


substrate_name: Penicillin N


enzyme_display_name: ferredoxin--NADP(+) reductase

organism: Anabaena sp.

substrate_name: reduced flavodoxin


substrate_name: NADH


organism: Plasmodium falciparum

substrate_name: NADPH


organism: Rhodobacter capsulatus


enzyme_display_name: pyranose oxidase

organism: Lyophyllum shimeji

substrate_name: L-sorbose


organism: Peniophora sp.

substrate_name: D-glucose


organism: Phanerodontia chrysosporium

substrate_name: ferricyanide


organism: Phlebiopsis gigantea


substrate_name: D-allose


organism: Trametes ochracea

substrate_name: ferricenium ion


substrate_name: D-galactose


substrate_name: D-melibiose


organism: Arabidopsis thaliana


organism: Bacillus subtilis

substrate_name: oxidized [2Fe-2S]-[rubredoxin]


organism: Chlorobaculum tepidum


organism: Escherichia coli

substrate_name: Fe(III)-EDTA


substrate_name: oxidized ferredoxin


organism: Lathyrus oleraceus


enzyme_display_name: cathepsin B

organism: Homo sapiens


organism: Hapsidospora chrysogena


enzyme_display_name: isocitrate dehydrogenase (NAD(+))

organism: Xylella fastidiosa

substrate_name: NADP+


substrate_name: NAD+


organism: Streptomyces clavuligerus

substrate_name: penicillin G


substrate_name: Penicillin N


substrate_name: NAD+; Isocitrate


organism: Campylobacter curvus


organism: Campylobacter sp.


organism: Congregibacter litoralis


enzyme_display_name: laccase

organism: Geobacter metallireducens


organism: Lentinus brumalis


organism: Panus rudis


enzyme_display_name: peroxidase

organism: Amycolatopsis sp.

substrate_name: H2O2; 2,4-Dichlorophenol


organism: Armoracia rusticana


substrate_name: 2-Chloro-4-methoxyphenol; H2O2


substrate_name: L-Dopa; H2O2


organism: Bacillus altitudinis

substrate_name: H2O2; Sinapate


enzyme_display_name: phenylalanine 4-monooxygenase


substrate_name: L-phenylalanine


substrate_name: tetrahydrobiopterin


organism: Rattus norvegicus

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


substrate_name: L-Phenylalanine


organism: Trametes ochracea

substrate_name: D-glucose


organism: Cephalosporium acremonium

substrate_name: Penicillin G; 2-Oxoglutarate; O2


substrate_name: Penicillin G


substrate_name: Penicillin N; 2-Oxoglutarate; O2


organism: Bos taurus


organism: Burkholderia pseudomallei


organism: Cucumis sativus

substrate_name: H2O2; 4-Methoxy-alpha-naphthol


organism: Euphorbia characias


organism: Caenorhabditis elegans


organism: Dictyostelium discoideum


organism: Homo sapiens


substrate_name: ferricenium hexafluorophosphate


organism: Saccharomyces cerevisiae

substrate_name: D-isocitrate


substrate_name: NAD+


substrate_name: D-galactose


organism: Ostreococcus tauri


substrate_name: NADP+


organism: Campylobacter concisus


substrate_name: NAD+; Isocitrate


enzyme_display_name: vanillyl-alcohol oxidase

organism: Penicillium simplicissimum


substrate_name: creosol


substrate_name: Eugenol


substrate_name: O2; Vanillyl alcohol


substrate_name: eugenol


organism: Rhodomicrobium vannielii


organism: Streptococcus suis


organism: Sus scrofa


organism: Trametes sp.


organism: Hydrogenobacter thermophilus


organism: Micromonas commoda


organism: Ostreococcus sp. 'lucimarinus'


organism: Phycomyces blakesleeanus

source_protein_accession: complex


organism: Methylovorus sp. MP688

substrate_name: Vanillyl alcohol


organism: Acidithiobacillus thiooxidans


organism: Bifidobacterium longum


organism: Bos taurus


organism: Campylobacter curvus


organism: Homo sapiens


substrate_name: chavicol


enzyme_display_name: phenylalanine dehydrogenase

organism: Bacillus badius

substrate_name: L-tyrosine


substrate_name: L-Phenylalanine


substrate_name: NAD+; H2O; L-Phenylalanine


organism: Lysinibacillus sphaericus

substrate_name: L-Norleucine


substrate_name: phenylpyruvate


organism: Pyrococcus furiosus


organism: Rattus norvegicus

substrate_name: D-threo-Isocitrate; NAD+


substrate_name: L-Methionine


substrate_name: L-Leucine


substrate_name: L-Isoleucine


substrate_name: L-Tyrosine


substrate_name: alpha-Ketovaline


substrate_name: L-Norvaline


substrate_name: L-Valine


organism: Penicillium simplicissimum

substrate_name: creosol


substrate_name: Eugenol


organism: Rhodococcus jostii


substrate_name: Vanillyl alcohol


substrate_name: vanillylamine


substrate_name: L-tyrosine


substrate_name: L-Phenylalanine


organism: Escherichia coli

substrate_name: But-2-enoyl-[acyl-carrier protein]


substrate_name: crotonoyl-CoA


organism: Haemophilus influenzae

substrate_name: NADH; H+; But-2-enoyl-[acyl-carrier protein]


organism: Mycobacterium tuberculosis

substrate_name: NADH


enzyme_display_name: shikimate dehydrogenase (NADP+)

organism: Arabidopsis thaliana

substrate_name: NADP+


substrate_name: shikimate


organism: Burkholderia pseudomallei


substrate_name: crotonyl-CoA


organism: Candidatus Liberibacter asiaticus


organism: Eimeria tenella


organism: Corynebacterium glutamicum


substrate_name: NADP+; Shikimate


substrate_name: NAD+


organism: Eucalyptus camaldulensis


substrate_name: NADPH


enzyme_display_name: uronate dehydrogenase

organism: Chromohalobacter israelensis

substrate_name: beta-D-galacturonate


substrate_name: beta-D-glucuronate


organism: Chromohalobacter salexigens


organism: Pseudomonas putida KT2440

substrate_name: D-glucuronate


organism: Pseudomonas syringae pv. tomato

substrate_name: D-Mannuronate


organism: Thermobispora bispora

substrate_name: D-glucuronic acid from a beechwood xylan


organism: Aquifex aeolicus


substrate_name: L-quinate


organism: Agrobacterium tumefaciens


organism: Pseudomonas putida


organism: Staphylococcus epidermidis


organism: Staphylococcus epidermidis RP62A


organism: Toxoplasma gondii


organism: Vitis vinifera


organism: Archaeoglobus fulgidus


organism: Aspergillus nidulans

substrate_name: NADPH; 3-Dehydroshikimate; H+


organism: Camellia sinensis


organism: Corynebacterium glutamicum


organism: Alistipes finegoldii


organism: Arabidopsis thaliana

substrate_name: NADH; H+; Crotonoyl-CoA


organism: Bacillus subtilis


organism: Burkholderia mallei


organism: Eucalyptus camaldulensis


organism: Haemophilus influenzae


organism: Helicobacter pylori


organism: Mycobacterium tuberculosis


organism: Mycolicibacterium smegmatis


organism: Plasmodium falciparum

substrate_name: H+; NADH; Crotonoyl-CoA


substrate_name: Unknown


substrate_name: 2-trans-Dodecenoyl-CoA; NADH; H+


substrate_name: NADH


substrate_name: octenoyl-CoA


substrate_name: crotonoyl-CoA


organism: Lysinibacillus sphaericus

substrate_name: L-Isoleucine


substrate_name: L-Methionine


substrate_name: L-Norleucine


substrate_name: NAD+; H2O; L-Phenylalanine


substrate_name: L-Norvaline


substrate_name: L-Phenylalanine


substrate_name: phenylpyruvate


organism: Pseudobacillus badius

substrate_name: L-phenylalanine


substrate_name: L-tyrosine


organism: Rhodococcus sp.

substrate_name: phenylacetone


organism: Yersinia pestis


substrate_name: L-Valine


substrate_name: alpha-Ketovaline


substrate_name: Unknown


organism: Pseudomonas aeruginosa

substrate_name: NADH; H+; trans-Dodec-2-enoyl-[acp]


substrate_name: NADH; H+; Crotonoyl-CoA


organism: Staphylococcus aureus

substrate_name: NADH; H+; Crotonyl-CoA


organism: Streptococcus pneumoniae

substrate_name: NADH; H+; But-2-enoyl-[acyl-carrier protein]


organism: uncultured bacterium

substrate_name: NADH


organism: Thermoactinomyces intermedius


substrate_name: L-Isoleucine


substrate_name: L-Norleucine


substrate_name: L-Leucine


organism: Rhodococcus sp. (in: high G+C Gram-positive bacteria)


substrate_name: L-Ethionine


substrate_name: L-Methionine


substrate_name: L-Norvaline


organism: Vibrio cholerae


organism: Xanthomonas oryzae

substrate_name: crotonyl-CoA


enzyme_display_name: pyruvate kinase

organism: Chlamydia trachomatis

substrate_name: Phosphoenolpyruvate; ADP


organism: Corynebacterium glutamicum


organism: Escherichia coli


organism: Homo sapiens

substrate_name: ADP; Phosphoenolpyruvate


organism: Lactococcus lactis subsp. cremoris


organism: Lactococcus lactis subsp. lactis


organism: Mus musculus


organism: Oryctolagus cuniculus

substrate_name: Phosphoenolpyruvate; dADP


organism: Rattus norvegicus


enzyme_display_name: phenylalanine ammonia-lyase

organism: Arabidopsis thaliana

substrate_name: L-Phenylalanine


substrate_name: L-Phe


substrate_name: L-tyrosine


substrate_name: L-phenylalanine


enzyme_display_name: beta-lactamase

organism: Serratia marcescens

substrate_name: H2O; Cephaloridine


substrate_name: H2O; Ampicillin


organism: Staphylococcus aureus


organism: Stenotrophomonas maltophilia

substrate_name: Nitrocefin; H2O


organism: Treponema pallidum

substrate_name: Penicillin G; H2O


organism: Anthoceros agrestis


organism: Mycobacterium tuberculosis

substrate_name: H2O; Nitrocefin


substrate_name: H2O; Penicillin G


organism: Nocardia asteroides


organism: Nocardia farcinica


organism: Ochrobactrum anthropi


organism: Proteus mirabilis


organism: Providencia stuartii


organism: Pseudomonas aeruginosa

substrate_name: H2O; Cefotaxime


organism: Serratia fonticola

substrate_name: H2O; Benzylpenicillin


organism: Aeromonas hydrophila


organism: Bacillus cereus


substrate_name: 6-Aminopenicillanate; H2O


organism: Bacillus licheniformis

substrate_name: H2O; Phenoxymethylpenicillin


organism: Bacteroides fragilis


organism: Burkholderia pseudomallei


organism: Citrobacter diversus


organism: Citrobacter freundii


organism: Enterobacter cloacae


organism: Escherichia coli


substrate_name: Benzylpenicillin; H2O


organism: Thermoactinomyces intermedius

substrate_name: L-Methionine


substrate_name: L-Leucine


substrate_name: L-Ethionine


substrate_name: L-Norvaline


substrate_name: NAD+; H2O; L-Phenylalanine


enzyme_display_name: arylamine N-acetyltransferase

organism: Mycobacterium smegmatis

substrate_name: Acetyl-CoA; Isoniazid


enzyme_display_name: anthranilate phosphoribosyltransferase

organism: Saccharomyces cerevisiae


organism: Sulfolobus solfataricus


organism: Amycolatopsis methanolica

substrate_name: Phosphoenolpyruvate; ADP


organism: Bos taurus


organism: Saccharolobus solfataricus

substrate_name: anthranilate


organism: Homo sapiens


organism: Larimichthys crocea

substrate_name: Z-L-Phe-L-Arg 7-amido-4-methylcoumarin


organism: Meretrix meretrix


organism: Mus musculus


organism: Naegleria fowleri


organism: Nicotiana benthamiana

substrate_name: Abz-GIVRAK-Dnp


organism: Rattus norvegicus


organism: Ricinus communis


organism: Klebsiella pneumoniae

substrate_name: H2O; Cephalothin


substrate_name: H2O; Imipenem


substrate_name: Nitrocefin; H2O


substrate_name: H2O; Nitrocefin


substrate_name: H2O; Penicillin G


organism: Klebsiella pneumoniae subsp. ozaenae


organism: Kluyvera ascorbata


organism: Moraxella catarrhalis

substrate_name: Amoxicillin; H2O


organism: Morganella morganii

substrate_name: H2O; Ampicillin


substrate_name: Benzylpenicillin; H2O


organism: Trichomonas vaginalis


organism: Trypanosoma brucei


organism: Ustilago maydis


organism: Zymomonas mobilis


enzyme_display_name: arginine kinase

organism: Cissites cephalotes

substrate_name: L-Arg


organism: Daphnia magna

substrate_name: ATP


organism: Euphausia superba

substrate_name: L-arginine


organism: Fenneropenaeus chinensis

substrate_name: L-Arginine; ATP


organism: Frankliniella occidentalis


organism: Haemonchus contortus


organism: Nicotiana benthamiana


organism: Rattus norvegicus

substrate_name: Z-Arg-Arg-p-nitroanilide


substrate_name: H2O; Z-Arg-Arg-p-nitroanilide


organism: Schistosoma mansoni


substrate_name: Z-Arg-Arg-p-nitroanilide; H2O


organism: Aeromonas hydrophila


organism: Arabidopsis thaliana

substrate_name: L-tyrosine


substrate_name: L-phenylalanine


substrate_name: trans-cinnamate


organism: Bambusa oldhamii

substrate_name: L-Phenylalanine


substrate_name: L-Phe


substrate_name: L-Tyr


organism: Jatropha curcas


organism: Kitagawia praeruptora


organism: Lycoris radiata


organism: Nicotiana tabacum


organism: Limulus polyphemus

substrate_name: L-Arginine phosphate; ADP


organism: Litopenaeus vannamei

substrate_name: ATP; dTDP


organism: Myxococcus xanthus

substrate_name: Nomega-phospho-L-Arg


organism: Toxocara canis


enzyme_display_name: prolyl oligopeptidase

organism: Bos taurus

substrate_name: H2O; Z-Gly-Pro-AMC


organism: Homo sapiens


enzyme_display_name: oligopeptidase B

organism: Serratia proteamaculans


enzyme_display_name: cathepsin B


organism: Capra hircus

substrate_name: Unknown


organism: Fasciola gigantica


organism: Escherichia coli

substrate_name: Penicillin G; H2O


substrate_name: H2O; Benzylpenicillin


substrate_name: H2O; Penicillin G


substrate_name: H2O; Nitrocefin


substrate_name: CENTA; H2O


substrate_name: H2O; Cephaloridine


substrate_name: H2O; Cefuroxime


substrate_name: H2O; Ampicillin


organism: Fluoribacter gormanii


substrate_name: H2O; Cefotaxime


substrate_name: H2O; Imipenem


organism: Klebsiella oxytoca


organism: Bambusa oldhamii

substrate_name: L-Phe


substrate_name: L-Tyr


organism: Cistanche deserticola


organism: Ephedra sinica

substrate_name: L-phenylalanine


organism: Glycine max

substrate_name: L-Phenylalanine


organism: Gossypium hirsutum


organism: Nicotiana tabacum


organism: Nostoc punctiforme


organism: Petroselinum crispum


substrate_name: trans-cinnamate


organism: Rhodobacter sphaeroides


enzyme_display_name: glutamine synthetase

organism: Anabaena azollae

substrate_name: ATP


substrate_name: L-Glutamate


organism: Arabidopsis thaliana

substrate_name: L-glutamate


substrate_name: ATP; L-Glutamate; NH3


organism: Exiguobacterium sp.

substrate_name: L-glutamine


substrate_name: ADP


organism: Homo sapiens

substrate_name: L-Glutamine; ADP; Phosphate


organism: Hordeum vulgare

substrate_name: Unknown


organism: Drosophila melanogaster


organism: Escherichia coli

substrate_name: L-Glutamate; NH3; ATP


substrate_name: L-Glu


organism: Rhodotorula glutinis


organism: Rhodotorula graminis

substrate_name: (2E)-3-nitro-cinnamic acid


substrate_name: (2E)-3-bromo-cinnamic acid


organism: Sorghum bicolor


organism: Trichormus variabilis


substrate_name: (2S)-2-amino-3-phenylpropanoic acid


organism: Zea mays


organism: Trichormus azollae


organism: Trypanosoma cruzi


organism: Tuber borchii


organism: Bacillus subtilis


substrate_name: hydroxylamine


organism: Camellia sinensis


organism: Canis familiaris


organism: Pseudomonas taetrolens


organism: Pyrococcus sp.


organism: Rattus norvegicus


organism: Ruminococcus albus


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Sulfolobus acidocaldarius


organism: Leishmania donovani


organism: Medicago truncatula


organism: Methanocaldococcus jannaschii


organism: Mus musculus


organism: Mycobacterium tuberculosis


organism: Oryza sativa


organism: Oryza sativa Japonica Group


organism: Phaseolus vulgaris


organism: Lysinibacillus sphaericus

substrate_name: DL-propargylglycine


substrate_name: L-phenylalanine


organism: Arabidopsis thaliana

substrate_name: NADP+


substrate_name: shikimate


organism: Auricularia auricula-judae

substrate_name: 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) (Dye-decolorizing peroxidase AauDyP1, at pH 4.5)


organism: Bubalus bubalis

substrate_name: 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (at pH 6.0 and 60 degrees Celsius)


organism: Equus caballus

substrate_name: bromide


organism: Metapenaeus ensis

substrate_name: ATP (at pH 8.5 and 30 degrees Celsius)


organism: Penaeus vannamei

substrate_name: ATP (at pH 8.6 and 30 degrees Celsius)


organism: Populus trichocarpa


organism: Homo sapiens

substrate_name: Acetyl-CoA; 2-Aminofluorene


organism: Bos taurus

substrate_name: Phosphoenolpyruvate; ADP


organism: Monoraphidium minutum

substrate_name: IDP


organism: Rattus norvegicus


organism: Ricinus communis


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: ADP


organism: Spinacia oleracea


organism: Sus scrofa


organism: Petroselinum crispum

substrate_name: L-Phenylalanine


organism: Unknown

substrate_name: L-Phe


organism: Beta vulgaris

substrate_name: Unknown


organism: Bradyrhizobium japonicum

substrate_name: hydroxylamine


organism: Hordeum vulgare


organism: Senna obtusifolia


substrate_name: Glu


organism: Triticum aestivum


organism: Xylanibacter ruminicola

substrate_name: ATP


organism: Zea mays


organism: Arabidopsis thaliana


substrate_name: NADP+


organism: Lysinibacillus sphaericus

substrate_name: DL-propargylglycine


substrate_name: L-phenylalanine


organism: Agrobacterium tumefaciens

substrate_name: D-glucuronic acid


enzyme_display_name: deacetoxycephalosporin-C synthase

organism: Streptomyces clavuligerus

substrate_name: Penicillin N


substrate_name: penicillin G


enzyme_display_name: dihydrolipoyl dehydrogenase

organism: Homo sapiens

substrate_name: NAD+


substrate_name: dihydrolipoamide


substrate_name: Pyruvate; NAD+; Coenzyme A


substrate_name: NAD+; 2-Oxoglutarate; Coenzyme A


substrate_name: NAD+; Coenzyme A; alpha-Ketovaline


substrate_name: NAD+; Coenzyme A; 2-Oxoglutarate


substrate_name: Lipoamide


substrate_name: NADH


substrate_name: Dihydrolipoamide; NAD+


organism: Solanum tuberosum


substrate_name: 2-Oxoglutarate; NAD+; Coenzyme A


substrate_name: 2-Oxopentanoate; NAD+; Coenzyme A


substrate_name: NADH; H+; (R)-Lipoate


organism: Thermus scotoductus

substrate_name: Cr(VI)


organism: Xenopus laevis


enzyme_display_name: sulfite oxidase

substrate_name: sulfite


organism: Gallus gallus


substrate_name: Sulfite; Cytochrome c; H2O


organism: Microbacterium luteolum


organism: Mycobacterium tuberculosis


substrate_name: Unknown


organism: Pisum sativum


substrate_name: Dihydrolipoylprotein


substrate_name: NAD+; Glycine; 5,6,7,8-Tetrahydrofolate


organism: Rattus norvegicus


organism: Escherichia coli


organism: Glycine max

substrate_name: ferrileghemoglobin


organism: Halobacterium volcanii

substrate_name: NAD+; Dihydrolipoamide


organism: Haloferax volcanii

substrate_name: NAD+


substrate_name: dihydrolipoamide


substrate_name: (S)-Lipoic acid


substrate_name: (R)-Lipoic acid


substrate_name: 1,2-Diselenolane-3-pentanoic acid


organism: Acidianus ambivalens


organism: Azotobacter vinelandii

substrate_name: Coenzyme A; NAD+; 2-Oxoglutarate


organism: Bos taurus

substrate_name: NAD+; Coenzyme A; Pyruvate


organism: Clostridium kluyveri


organism: Corynebacterium glutamicum

substrate_name: NAD+; Coenzyme A; 2-Oxoglutarate


substrate_name: Pyruvate; NAD+; Coenzyme A


substrate_name: NADP+


organism: Zea mays

substrate_name: sulfite


enzyme_display_name: thymidylate synthase

organism: Bacillus subtilis

substrate_name: 5,10-Methylenetetrahydrofolate; dUMP


organism: Bacteriophage T4


organism: Crithidia fasciculata


substrate_name: dUMP


organism: Homo sapiens


organism: Lactobacillus casei


organism: Leishmania major


organism: Rattus norvegicus


organism: Toxoplasma gondii

substrate_name: H+; NADPH; 5,10-Methylenetetrahydrofolate; dUMP


organism: Trypanosoma cruzi


enzyme_display_name: glycine hydroxymethyltransferase

organism: Alloalcanivorax dieselolei

substrate_name: L-serine


organism: Aphanothece halophytica

substrate_name: glycine


organism: Arabidopsis thaliana

substrate_name: tetrahydrofolate


substrate_name: Tetrahydropteroyl di-L-glutamate


substrate_name: L-Serine; 5,6,7,8-Tetrahydrofolate


substrate_name: Tetrahydropteroyl penta-L-glutamate


substrate_name: Tetrahydropteroyl tri-L-glutamate


substrate_name: Tetrahydropteroyl tetra-L-glutamate


organism: Bombyx mori


organism: Danio rerio


substrate_name: serine


organism: Escherichia coli


substrate_name: L-Serine


organism: Geobacillus stearothermophilus


substrate_name: L-allo-Threonine


organism: Glutamicibacter nicotianae


organism: Glycine max


substrate_name: D-Serine


organism: Idiomarina loihiensis

substrate_name: DL-beta-Phenylserine


organism: Leishmania donovani


organism: Methanosarcina barkeri


organism: Oryctolagus cuniculus

substrate_name: L-Ser


organism: Plasmodium vivax


organism: Psychromonas ingrahamii


organism: Rattus norvegicus


organism: Ovis aries


organism: Plasmodium falciparum


enzyme_display_name: hypoxanthine phosphoribosyltransferase

organism: Trypanosoma cruzi

substrate_name: IMP


substrate_name: diphosphate


substrate_name: Hypoxanthine


substrate_name: 5-Phospho-alpha-D-ribose 1-diphosphate


organism: Saccharomyces cerevisiae


organism: Thermoanaerobacter tengcongensis


substrate_name: Guanine


organism: Thermus thermophilus

substrate_name: guanine


substrate_name: 5-phospho-alpha-D-ribose 1-diphosphate


substrate_name: hypoxanthine


organism: Trypanosoma brucei brucei


organism: Legionella pneumophila


organism: Leishmania tarentolae


organism: Mycobacterium tuberculosis


substrate_name: xanthine


organism: Thermoplasma acidophilum

substrate_name: L-serine


substrate_name: L-Serine; 5,6,7,8-Tetrahydrofolate


enzyme_display_name: glycogen phosphorylase

organism: Corynebacterium callunae

substrate_name: D-Glucose 1-phosphate


substrate_name: starch


substrate_name: Starch; Phosphate


organism: Escherichia coli

substrate_name: Maltoheptaose; Phosphate


substrate_name: GMP


organism: Agrobacterium sp.

substrate_name: Unknown


organism: Bacillus cereus

substrate_name: phosphoenolpyruvate


organism: Bacillus subtilis


organism: Brucella anthropi


organism: Oryctolagus cuniculus

substrate_name: Glycogen; D-Glucose 1-phosphate


organism: Solanum tuberosum


organism: Zea mays


organism: Homo sapiens


substrate_name: Hypoxanthine


substrate_name: IMP


substrate_name: diphosphate


substrate_name: Guanine


substrate_name: guanine


substrate_name: shikimate 3-phosphate


substrate_name: Phosphoenolpyruvate


organism: Stutzerimonas stutzeri


substrate_name: Isopentenyl diphosphate; cis,trans,trans-Geranylgeranyl diphosphate


substrate_name: Isopentenyl diphosphate


substrate_name: trans,trans-Farnesyl diphosphate


substrate_name: (2E,6E)-farnesyl diphosphate


organism: Halothermothrix orenii


organism: Janibacter sp.


organism: Oryza sativa


organism: Pseudomonas fluorescens


organism: Rahnella aquatilis


organism: Streptococcus pneumoniae


substrate_name: Phosphate


organism: Micrococcus luteus

substrate_name: (2Z,6E,10E)-geranylgeranyl diphosphate


enzyme_display_name: cysteine synthase

organism: Arabidopsis thaliana

substrate_name: O-Acetyl-L-serine


substrate_name: O-Acetyl-L-serine; Sulfide


organism: Salmonella typhimurium

substrate_name: Hydrogen sulfide


organism: Schizosaccharomyces pombe

substrate_name: O-Acetyl-L-serine; Hydrogen sulfide


substrate_name: Hydrogen sulfide; O-Acetyl-L-serine


organism: Bacillus anthracis

substrate_name: O-acetyl-L-serine


organism: Bacillus subtilis


organism: Caenorhabditis elegans

substrate_name: Cyanide


substrate_name: S-Sulfo-L-cysteine


substrate_name: L-Cysteine


organism: Escherichia coli


substrate_name: Isopentenyl diphosphate; trans,trans-Farnesyl diphosphate


organism: Helicobacter pylori


organism: Lactobacillus plantarum

substrate_name: trans,trans-Farnesyl diphosphate; Isopentenyl diphosphate


substrate_name: Sulfide


organism: Leucaena leucocephala


organism: Microcystis aeruginosa


organism: Mimosa pudica


substrate_name: hydrogen sulfide


substrate_name: Sulfide; O-Acetyl-L-serine


substrate_name: O-acetyl-L-Ser


substrate_name: L-Serine; Acetyl-CoA


substrate_name: O-Acetyl-L-serine; Thiosulfate


substrate_name: (2Z,6E,10E)-geranylgeranyl diphosphate


substrate_name: (2E,6E)-farnesyl diphosphate


organism: Aeropyrum pernix

substrate_name: O-Acetyl-L-serine


substrate_name: O-Phospho-L-serine


substrate_name: Hydrogen sulfide


substrate_name: Hydrogen sulfide; O-Acetyl-L-serine


substrate_name: O-Acetyl-L-serine; Sulfide


organism: Streptomyces lavendulae

substrate_name: thiosulfate


organism: Thermus thermophilus


enzyme_display_name: protein farnesyltransferase

organism: Rattus norvegicus


substrate_name: Farnesyl diphosphate; Protein cysteine


enzyme_display_name: aspartate transaminase

organism: Advenella mimigardefordensis

substrate_name: L-aspartate


substrate_name: L-Aspartate


organism: Solanum tuberosum


organism: Spinacia oleracea


substrate_name: Sulfide


substrate_name: hydrogen sulfide


substrate_name: L-Cysteine


organism: Arabidopsis thaliana

substrate_name: L-Aspartate; 2-Oxoglutarate


substrate_name: Prephenate


substrate_name: L-Aspartate; Prephenate


substrate_name: L-Glutamate


substrate_name: oxaloacetate


substrate_name: L-Tyrosine


substrate_name: L-Phe


substrate_name: L-glutamate


organism: Geobacillus thermopakistaniensis


organism: Homo sapiens


organism: Mycobacterium tuberculosis


substrate_name: kynurenine


organism: Panicum miliaceum


organism: Petunia hybrida


substrate_name: L-Arogenate


organism: Bacillus sp.


organism: Bacillus subtilis


organism: Escherichia coli


enzyme_display_name: branched-chain-amino-acid transaminase

organism: Thermococcus sp.


substrate_name: L-norleucine


substrate_name: L-Isoleucine


substrate_name: L-norvaline


substrate_name: phenylpyruvate


substrate_name: L-Valine


organism: Burkholderia mallei


substrate_name: crotonyl-[acyl-carrier protein]


organism: Burkholderia pseudomallei


substrate_name: L-Leucine


organism: Pinus pinaster

substrate_name: L-Aspartate; 2-Oxoglutarate


organism: Rattus norvegicus


organism: Rattus rattus


organism: Rhizobium meliloti


organism: Saccharolobus solfataricus

substrate_name: L-aspartate


organism: Sinorhizobium meliloti


organism: Gluconobacter oxydans


organism: Haliangium ochraceum


substrate_name: L-leucine


organism: Helicobacter pylori

substrate_name: L-isoleucine


organism: Homo sapiens

substrate_name: L-Leucine; 2-Oxoglutarate


substrate_name: L-Glutamate


substrate_name: L-Isoleucine; alpha-Ketovaline


organism: Sus scrofa


organism: Thermus thermophilus


organism: Triticum aestivum


substrate_name: L-Aspartate


organism: Trypanosoma brucei


organism: Trypanosoma cruzi


substrate_name: L-tyrosine


substrate_name: L-valine


organism: Methanococcus aeolicus

substrate_name: L-Isoleucine; 2-Ketoglutaric acid


organism: Mycobacterium tuberculosis

substrate_name: L-glutamate


organism: Pseudomonas aeruginosa


organism: Rattus norvegicus


organism: Synechocystis sp.


organism: Thermobaculum terrenum


organism: Thermococcus sp.


organism: Arabidopsis thaliana

substrate_name: L-Glutamate; 3-Methyl-2-oxobutanoate


organism: Bacillus anthracis


organism: Bacillus cereus


organism: Bacillus subtilis


organism: Brevibacillus brevis


organism: Escherichia coli


substrate_name: L-Phenylalanine


organism: Thermoproteus uzoniensis


substrate_name: pyruvate


substrate_name: L-alanine


organism: Vulcanisaeta moutnovskia

substrate_name: L-Ornithine


enzyme_display_name: acetate kinase

organism: Methanosarcina thermophila

substrate_name: Acetate


substrate_name: ATP


substrate_name: ADP


substrate_name: ATP; D-Fructose 6-phosphate


substrate_name: beta-D-Fructose 6-phosphate; ATP


substrate_name: D-Fructose 6-phosphate


organism: Spinacia oleracea

substrate_name: beta-D-fructose 6-phosphate


substrate_name: L-Valine


substrate_name: L-norvaline


substrate_name: L-valine


organism: Bos taurus


organism: Gallus gallus


organism: Homo sapiens

substrate_name: D-Fructose 6-phosphate; ATP


mutation_signature: recombinant His-tagged HBP1 deletion mutant


mutation_signature: is-tagged HBP1 deletion mutant


substrate_name: ADP; Acetyl phosphate


organism: Fructilactobacillus sanfranciscensis


organism: Lactococcus lactis

substrate_name: acetate


organism: Methanosarcina mazei


organism: Trypanosoma brucei


organism: Enterococcus faecalis

substrate_name: ATP; Acetate


substrate_name: acetyl phosphate


substrate_name: ATP; beta-D-Fructose 6-phosphate


organism: Rattus norvegicus


enzyme_display_name: creatine kinase

substrate_name: Phosphocreatine


substrate_name: Creatine


substrate_name: ATP


substrate_name: ITP


substrate_name: TTP


substrate_name: UTP


substrate_name: GTP


substrate_name: CTP


substrate_name: ADP


substrate_name: ADP; Phosphocreatine


substrate_name: Phosphocreatine; dCDP


organism: Oryctolagus cuniculus


substrate_name: ATP; Creatine


enzyme_display_name: adenylate kinase

organism: Arabidopsis thaliana

substrate_name: ATP; AMP


organism: Bacillus subtilis


substrate_name: AMP


substrate_name: acetate


substrate_name: acetyl phosphate


organism: Methylotuvimicrobium alcaliphilum


organism: Porphyromonas gingivalis


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Shewanella sp.


organism: Cryptosporidium muris

substrate_name: glycocyamine


substrate_name: N-ethylglycocyamine


substrate_name: Phosphocreatine


organism: Bordetella pertussis


organism: Bos taurus


organism: Clonorchis sinensis


organism: Cyprinus carpio


organism: Escherichia coli


organism: Gallus gallus


organism: Geobacillus stearothermophilus


organism: Homo sapiens


substrate_name: ATP


organism: Plasmodium falciparum


organism: Saccharomyces cerevisiae


organism: Streptococcus pneumoniae

substrate_name: Unknown


organism: Strongylocentrotus purpuratus


organism: Sulfolobus acidocaldarius


organism: Thermotoga neapolitana


substrate_name: ATP; Nicotinamide nucleotide


substrate_name: nicotinamide ribonucleotide


substrate_name: Nicotinamide nucleotide


substrate_name: Tiazofurin monophosphate


substrate_name: ITP


substrate_name: nicotinic acid mononucleotide


substrate_name: Nicotinate D-ribonucleotide


organism: Leishmania braziliensis


organism: Methanothermobacter thermautotrophicus


organism: Giardia duodenalis


organism: Haemophilus influenzae


substrate_name: Nicotinamide nucleotide; ATP


substrate_name: GTP


substrate_name: ATP; Tiazofurin monophosphate


substrate_name: AMP


organism: Jeotgalibacillus marinus


organism: Leishmania donovani


organism: Megalodesulfovibrio gigas


organism: Methanococcus maripaludis


organism: Mus musculus


organism: Oryctolagus cuniculus

substrate_name: ATP; AMP


organism: Penicillium chrysogenum


organism: Plasmodium falciparum


organism: Salmonella enterica


organism: Salmonella typhimurium


enzyme_display_name: acetylcholinesterase

organism: Bungarus fasciatus

substrate_name: H2O; Acetylcholine


organism: Dictyocaulus viviparus

substrate_name: Acetylthiocholine; H2O


enzyme_display_name: alkaline phosphatase

organism: Escherichia coli

substrate_name: 4-nitrophenyl phosphate


organism: Electrophorus electricus

substrate_name: H2O; Acetylthiocholine


organism: Homo sapiens


substrate_name: Acetylthiocholine


substrate_name: acetylthiocholine


organism: Stomoxys calcitrans


organism: Antarctic bacterium TAB5


substrate_name: 4-Nitrophenyl phosphate


substrate_name: H2O; 4-Nitrophenyl phosphate


substrate_name: methyl phosphate


organism: Gallus gallus


organism: Geobacillus thermodenitrificans


organism: Halobacterium salinarum


organism: Helicoverpa armigera


substrate_name: H2O; Phenolic phosphate


organism: Bacillus licheniformis


organism: Bos taurus

substrate_name: 3-(4-methoxyspiro [1,2-dioxetane-3,2'-(5'-chloro)-tricyclo [3.3.1.13,7]-decan]-4-yl)phenyl phosphate


substrate_name: Phosphoenolpyruvate; H2O


organism: Burkholderia cenocepacia

substrate_name: phosphoenolpyruvate


organism: Cobetia marina


substrate_name: 4-Nitrophenyl phosphate; H2O


organism: Mus musculus

substrate_name: Unknown


organism: Rattus norvegicus


organism: Saccharococcus caldoxylosilyticus


organism: Shewanella sp. T3-3


organism: Sphingobium sp. TCM1


organism: Thermus sp.


organism: Thermus sp. NTU-237


organism: Escherichia coli

substrate_name: GMP


substrate_name: AMP


substrate_name: dGMP


substrate_name: dTMP


substrate_name: dUMP


substrate_name: UMP


substrate_name: dAMP


substrate_name: dCMP


substrate_name: dIMP


substrate_name: 4-Nitrophenyl phosphate


substrate_name: H2O; 4-Nitrophenyl phosphate


organism: Thermus thermophilus

substrate_name: 4-nitrophenyl phosphate


organism: Vibrio sp. G15-21


organism: Bacillus subtilis


substrate_name: D-Ribose 5-phosphate


organism: Homo sapiens

substrate_name: H2O; AMP


substrate_name: ATP; D-2'-Deoxycarbocyclic guanosine


substrate_name: H2O; IMP


substrate_name: H2O; dUMP


organism: Boophilus microplus


organism: Drosophila melanogaster


substrate_name: H2O; GMP


substrate_name: GMP


substrate_name: dGMP


substrate_name: AMP; H2O


organism: Helicobacter pylori


substrate_name: Inosine


substrate_name: CMP


substrate_name: H2O; CMP


substrate_name: AMP


organism: Mycoplasma pulmonis

substrate_name: H2O; 5'-AMP


enzyme_display_name: alpha-amylase

organism: Alteromonas haloplanktis


organism: Anabaena sp.

substrate_name: oyster glycogen


organism: Bacillus amyloliquefaciens

substrate_name: starch


substrate_name: soluble starch


organism: Bacillus licheniformis


organism: Hordeum vulgare


substrate_name: amylose DP17


substrate_name: amylose DP440


enzyme_display_name: alpha-glucosidase

organism: Apis mellifera

substrate_name: Phenyl alpha-D-glucoside


substrate_name: maltopentaose


substrate_name: Nigerose


substrate_name: turanose


substrate_name: maltotetraose


organism: Aspergillus nidulans

substrate_name: H2O; Maltose


substrate_name: alpha,alpha-Trehalose


substrate_name: Maltose


substrate_name: Isomaltose


substrate_name: Maltotriose


organism: Apis cerana indica


substrate_name: isomaltose


substrate_name: 4-nitrophenyl alpha-D-glucoside


substrate_name: sucrose


substrate_name: p-Nitrophenyl-alpha-D-glucoside


substrate_name: Sucrose


substrate_name: Kojibiose


substrate_name: Maltohexaose


organism: Sus scrofa


organism: Tepidimonas fonticaldi

substrate_name: soluble potato starch


organism: Thermobifida fusca


organism: Thermotoga neapolitana

substrate_name: maltopentaose


substrate_name: 4-nitrophenyl alpha-D-maltohexaoside


substrate_name: maltotriose


substrate_name: maltoheptaose


organism: Tribolium castaneum

substrate_name: amylopectin


organism: uncultured organism


organism: Vigna angularis

substrate_name: Amylose; H2O


organism: Helicoverpa armigera

substrate_name: starch


organism: Homo sapiens

substrate_name: Maltotriose; H2O


substrate_name: Maltotriose


substrate_name: amylose DP17


substrate_name: Nigerose


organism: Bacillus sp.

substrate_name: H2O; Trehalose


organism: Caldanaerobacter subterraneus subsp. tengcongensis

substrate_name: 4-nitrophenyl alpha-D-glucopyranoside


organism: Culex quinquefasciatus


organism: Erwinia rhapontici

substrate_name: Maltulose


substrate_name: Trehalulose


substrate_name: Leucrose


substrate_name: Sucrose


organism: Bacillus licheniformis


organism: Bacillus sp. dsh19-1

substrate_name: soluble starch


organism: Bacillus subtilis

substrate_name: H2O; o-Nitrophenyl-alpha-maltoside


organism: Bifidobacterium longum


organism: Callosobruchus chinensis


organism: Drosophila melanogaster


organism: Euplotes focardii


organism: Geobacillus thermoleovorans

substrate_name: raw starch


organism: Glycine max

substrate_name: H2O; Starch


organism: Hordeum vulgare


organism: Lactobacillus amylovorus


organism: Lactobacillus manihotivorans

substrate_name: H2O; Amylose


organism: Lactobacillus plantarum

substrate_name: Amylose


organism: Moneuplotes crassus

substrate_name: starch


organism: Paenibacillus sp. SSG-1

substrate_name: maltopentaose


substrate_name: amylose


substrate_name: maltose


substrate_name: maltoheptaose


substrate_name: maltotriose


organism: Priestia megaterium


organism: Pseudoalteromonas haloplanktis


organism: Pyrococcus sp.

substrate_name: glycogen


organism: Ruminococcus bromii


organism: Solanum tuberosum

substrate_name: maltotetraose


substrate_name: Maltotriose


substrate_name: Maltohexaose


organism: Sulfolobus acidocaldarius


substrate_name: maltohexaose


substrate_name: 4-nitrophenyl alpha-D-glucopyranoside


organism: Sulfurisphaera tokodaii


organism: Erwinia rhapontici

substrate_name: Maltitol


substrate_name: palatinose


substrate_name: Maltose


substrate_name: turanose


substrate_name: alpha,alpha-Trehalose


organism: Ferroplasma acidiphilum


substrate_name: sucrose


organism: Mortierella alliacea


substrate_name: maltopentaose


substrate_name: H2O; Maltose


organism: Rattus norvegicus

substrate_name: H2O; p-Nitrophenyl-alpha-D-glucoside


substrate_name: Maltose; H2O


substrate_name: p-Nitrophenyl-alpha-D-glucoside


substrate_name: maltoheptaose


substrate_name: panose


substrate_name: isomaltose


substrate_name: maltose


substrate_name: maltotetraose


organism: Thermoplasma acidophilum


substrate_name: 4-nitrophenyl alpha-D-glucopyranoside


enzyme_display_name: alpha-galactosidase

organism: Geobacillus stearothermophilus

substrate_name: 4-nitrophenyl alpha-D-galactopyranoside


substrate_name: raffinose


substrate_name: kojibiose


substrate_name: maltotriose


organism: Thermotoga maritima

substrate_name: p-Nitrophenyl-alpha-D-glucoside; H2O


organism: Thermus thermophilus

substrate_name: Isomaltose


substrate_name: H2O; alpha,alpha-Trehalose


substrate_name: alpha,alpha-Trehalose


substrate_name: Maltose


organism: Bacteroides fragilis

substrate_name: p-Nitrophenyl-alpha-D-galactoside


substrate_name: H2O; Gal-alpha1->3(Fuc-alpha1->2)Gal


organism: Bacteroides thetaiotaomicron

substrate_name: Melibiose


substrate_name: H2O; p-Nitrophenyl-alpha-D-galactoside


substrate_name: 4-nitrophenyl alpha-D-galactoside


organism: Bifidobacterium breve


organism: Fusarium sp.


organism: Rhizomucor miehei

substrate_name: stachyose


substrate_name: melibiose


organism: Saccharolobus solfataricus

substrate_name: p-nitrophenyl alpha-D-galactopyranoside


organism: Saccharomyces cerevisiae


organism: Saccharopolyspora erythraea


organism: Sphingomonas sp.


organism: Sulfolobus solfataricus


organism: Thermothielavioides terrestris

substrate_name: 4-nitrophenyl alpha-D-galactopyranoside


substrate_name: 4-O-methylphenyl alpha-D-galactoside


substrate_name: 4-bromophenyl alpha-D-galactoside


organism: Kocuria sp. Mn22


organism: Luteimicrobium xylanilyticum

substrate_name: beechwood xylan


organism: Malbranchea cinnamomea

substrate_name: oat spelt xylan


organism: Massilia sp. RBM26


organism: Neocallimastix patriciarum


organism: Nesterenkonia xinjiangensis


organism: Niallia circulans


organism: Penicillium citrinum

substrate_name: birchwood xylan


organism: Penicillium sp. CGMCC 1669


organism: Pseudoalteromonas haloplanktis

substrate_name: xylan


organism: Pseudopedobacter saltans


organism: Teredinibacter turnerae


organism: Thermoanaerobacterium saccharolyticum


organism: Thermochaetoides thermophila


organism: Thermomyces lanuginosus


organism: Thermothelomyces thermophilus

substrate_name: Remazol brilliant blue R 4-O-methyl-D-glucuronoxylan; H2O


organism: Thermotoga maritima


organism: Trichoderma reesei


organism: uncultured bacterium

substrate_name: oat-spelt xylan


organism: Thermus sp. T2


organism: Alicyclobacillus sp.

substrate_name: xylotetraose


organism: Aspergillus sulphureus


organism: Bacillus circulans

substrate_name: H2O; 1,4-beta-D-Xylan


organism: Bacillus subtilis


organism: Bacillus thermodenitrificans

substrate_name: 1,4-beta-D-Xylan; H2O


organism: Cellvibrio japonicus

substrate_name: H2O; 4-Nitrophenyl-beta-D-xylobioside


organism: Fusarium oxysporum f. sp. vasinfectum


organism: Geobacillus stearothermophilus


organism: Hordeum vulgare


organism: Pseudothermotoga thermarum


organism: Rhizophlyctis rosea


organism: Rhodothermaceae bacterium RA


organism: Scheffersomyces stipitis


organism: Sphingobacterium sp. TN19


organism: Streptomyces fradiae


organism: Streptomyces sp. TN119


organism: Talaromyces funiculosus


organism: Talaromyces pinophilus

substrate_name: wheat arabinoxylan


organism: Teredinibacter turnerae

substrate_name: marine beta-1,3-beta-1,4-xylan


substrate_name: arabinoxylan


substrate_name: raffinose


substrate_name: 4-nitrophenyl alpha-D-galactopyranoside


organism: Homo sapiens


organism: Mus musculus


organism: Phanerodontia chrysosporium

substrate_name: 1-naphthyl alpha-D-galactoside


organism: Pseudoalteromonas sp. KMM 701

substrate_name: Unknown


organism: Rhizomucor miehei


substrate_name: melibiose


enzyme_display_name: subtilisin

organism: Bacillus lentus

substrate_name: Peptidyl-p-nitroanilide


organism: Bacillus amyloliquefaciens

substrate_name: N-Acetyl-L-tyrosine methyl ester


substrate_name: N-Acetyl-L-tryptophan methyl ester


substrate_name: Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide


enzyme_display_name: peptidyl-dipeptidase A

organism: Oryctolagus cuniculus

substrate_name: Hip-His-Leu


substrate_name: Angiotensin I


substrate_name: Angiotensin I; H2O


organism: Struthio camelus australis


substrate_name: N-Acetyl-L-phenylalanine methyl ester


organism: uncultured bacterium

substrate_name: oat-spelt xylan


substrate_name: beechwood xylan


organism: Drosophila melanogaster


substrate_name: Hip-His-Leu; H2O


substrate_name: N-Acetyl-Ser-Asp-Lys-Pro


substrate_name: Leu-enkephalin


substrate_name: Leu-enkephalinamide


substrate_name: H2O; Hip-His-Leu


substrate_name: Peptidyl-p-nitroanilide; H2O


organism: Bacillus licheniformis


substrate_name: N-Acetyl-L-tryptophan methyl ester; H2O


organism: Bacillus subtilis


substrate_name: furanacryloyl-L-Phe-Gly-Gly


substrate_name: Succinyl-Ala-Ala-Pro-Ala-p-nitroanilide


substrate_name: Succinyl-Ala-Ala-Pro-Met-p-nitroanilide


substrate_name: Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide


organism: Plasmodium falciparum

substrate_name: Ac-LVSADNIDIS; H2O


enzyme_display_name: arginase

substrate_name: L-arginine


substrate_name: L-Arginine; H2O


organism: Bacillus brevis

substrate_name: H2O; L-Arginine


organism: Bacillus caldovelox


organism: [Bacillus] caldovelox


organism: Bos taurus


organism: Rattus norvegicus


substrate_name: Unknown


organism: Saccharomyces cerevisiae


organism: Schistosoma mansoni


organism: Solanum lycopersicum


organism: Sulfobacillus acidophilus


organism: Sus scrofa


organism: Geobacillus thermodenitrificans


organism: Glaciozyma antarctica


organism: Helicobacter pylori


organism: Heteropneustes fossilis


organism: Homo sapiens


organism: Plasmodium falciparum 3D7


organism: Leishmania amazonensis


organism: Leishmania donovani


organism: Leishmania infantum


organism: Leishmania mexicana


organism: Mus musculus


organism: Neurospora crassa


organism: Oryza sativa


organism: Plasmodium falciparum


enzyme_display_name: orotidine-5'-phosphate decarboxylase

organism: Methanothermobacter thermautotrophicus

substrate_name: orotidine 5'-phosphate


organism: Xenopus laevis


organism: Escherichia coli

substrate_name: Orotidine 5'-phosphate


organism: Methanobacterium thermoautotrophicus


enzyme_display_name: dihydrolipoyl dehydrogenase

organism: Unknown

substrate_name: H2O; 2-Oxoglutarate; Ferricyanide


substrate_name: NAD+; Dihydrolipoamide


organism: Lupinus angustifolius


organism: Medicago sativa

substrate_name: oxaloacetate


organism: Oryctolagus cuniculus


substrate_name: L-aspartate


organism: Ovis aries


organism: Panicum miliaceum


organism: Rattus norvegicus


organism: Sus scrofa


organism: Canis lupus familiaris


organism: Homo sapiens

substrate_name: L-Glutamate; 4-Methyl-2-oxopentanoate


organism: Saccharomyces cerevisiae

substrate_name: beta-D-fructose 6-phosphate


enzyme_display_name: (S)-hydroxynitrile lyase

organism: Hevea brasiliensis

substrate_name: acetone cyanohydrin


organism: Manihot esculenta

substrate_name: Acetone cyanohydrin


substrate_name: Mandelonitrile


substrate_name: (S)-mandelonitrile


substrate_name: 2-thiophene carboxaldehyde


substrate_name: 4-biphenyl carboxaldehyde


substrate_name: 1-naphthalene carboxaldehyde


organism: Plasmodium falciparum

substrate_name: NAD+


enzyme_display_name: sulfite oxidase

substrate_name: sulfite


substrate_name: phosphoenolpyruvate


organism: Zea mays

substrate_name: shikimate 3-phosphate


enzyme_display_name: aspartate transaminase

organism: Arabidopsis thaliana


organism: Atriplex spongiosa


organism: Eleusine coracana


organism: Gallus gallus


organism: Hyalomma dromedarii


organism: Lupinus albus

substrate_name: L-Aspartate; 2-Oxoglutarate


organism: Baliospermum montanum


substrate_name: (R)-mandelonitrile


substrate_name: (S)-Mandelonitrile


substrate_name: Cyanide


organism: Unknown

substrate_name: Glp-Ala-Ala-Leu-p-Nitroanilide; H2O


substrate_name: L-arginine


substrate_name: fructose 6-phosphate


organism: Rattus norvegicus

substrate_name: beta-D-fructose 6-phosphate


organism: Methanosarcina thermophila

substrate_name: ATP


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


organism: Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)


organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)

substrate_name: AMP (at pH 7.5)


organism: Escherichia coli (strain K12)

substrate_name: ATP (at pH 7.4 and 30 degrees Celsius)


organism: Homo sapiens

substrate_name: AMP (with ATP as phosphate donor)


substrate_name: AMP


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Spirochaeta sp.

substrate_name: acetate


organism: Mus musculus


organism: Aspergillus oryzae

substrate_name: p-nitrophenyl phosphate


substrate_name: H2O; 4-Nitrophenyl phosphate


organism: Bos taurus

substrate_name: H2O; AMP


organism: Sus scrofa


organism: Aspergillus niger

substrate_name: H2O; Raffinose


organism: Phlebia radiata

substrate_name: p-nitrophenyl alpha-D-galactopyranoside


substrate_name: raffinose


organism: Melanocarpus albomyces

substrate_name: birchwood xylan


organism: Trichoderma sp.


enzyme_display_name: cysteine synthase

organism: Arabidopsis thaliana

substrate_name: O-acetylserine (at pH 7.0 and 25 degrees Celsius) for the cysteine synthase activity


substrate_name: L-cysteine for the cystathionine gamma-lyase activity


organism: Caenorhabditis elegans

substrate_name: O-acetylserine


substrate_name: O-acetylserine (at 25 degrees Celsius and pH 7.5)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: O-acetyl-L-homoserine (OAH) (at 30 degrees Celsius in potassium phosphate buffer)


substrate_name: O-acetyl-L-homoserine


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: O-acetyl-L-serine as isolated subunit and in complex with CysK


organism: Solanum tuberosum

substrate_name: L-cysteine for the L-3-cyanoalanine synthase activity (in the presence of 5 mM KCN)


substrate_name: O(3)-acetyl-L-serine for the cysteine synthase activity (in the presence of 2.5 mM Na(2)S)


organism: Spinacia oleracea

substrate_name: O(3)-acetyl-L-serine for the cysteine synthase activity with the recombinant enzyme


organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)

substrate_name: lipoate


organism: Hymenolepis diminuta

substrate_name: NADH for the NADH -> NAD reaction


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: NAD(+)


organism: Thermus scotoductus (strain ATCC 700910 / SA-01)

substrate_name: Cr(VI)


enzyme_display_name: thymidylate synthase

substrate_name: dUMP


enzyme_display_name: glycine hydroxymethyltransferase

substrate_name: L-serine (at pH 6.5 and 30 degrees Celsius)


organism: Homo sapiens

substrate_name: L-serine (with HEPES)


substrate_name: L-serine


organism: Oryctolagus cuniculus


organism: Ovis aries


enzyme_display_name: glycogen phosphorylase

organism: Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)

substrate_name: maltoheptaose (at 60 degrees Celsius)


organism: Rhizobium meliloti

substrate_name: aspartate


substrate_name: L-aspartate


enzyme_display_name: branched-chain-amino-acid transaminase

substrate_name: 4-methyl-2-oxopentanoate (4MOP)


substrate_name: L-leucine


organism: Bacillus subtilis (strain 168)

substrate_name: isoleucine (with 10 mM ketomethiobutyrate)


organism: Humulus lupulus

substrate_name: glutamate


organism: Rattus norvegicus


organism: Arabidopsis thaliana

substrate_name: fructose-6-phosphate for the 6-phosphofructo-2-kinase activity (at pH 6.0 and 25 degrees Celsius)


substrate_name: beta-D-fructose 6-phosphate


enzyme_display_name: alkaline phosphatase

organism: Elizabethkingia meningoseptica

substrate_name: 4-nitrophenyl phosphate


organism: Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805)


substrate_name: myo-inositol phosphate


organism: Bos taurus

substrate_name: IMP (in absence of allosteric activator)


organism: Escherichia coli (strain K12)


substrate_name: UMP (at pH 7 and at 25 degrees Celsius)


substrate_name: IMP (with manganese ions as cofactor and at pH 9)


organism: Gallus gallus

substrate_name: IMP


substrate_name: AMP


substrate_name: IMP (in presence of the allosteric activator ATP)


substrate_name: m(7)GMP (at 37 degrees Celsius)


enzyme_display_name: adenylate kinase

organism: Sus scrofa

substrate_name: ThDP


substrate_name: NMN


organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)


substrate_name: beta-nicotinamide D-ribonucleotide


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: ATP


substrate_name: nicotinamide mononucleotide


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: ribosylnicotinamide


enzyme_display_name: acetylcholinesterase

organism: Bungarus fasciatus

substrate_name: acetylcholine (at pH 7.5)


organism: Caenorhabditis elegans

substrate_name: acetylthiocholine


organism: Danio rerio

substrate_name: acetylcholine


organism: Spinacia oleracea

substrate_name: O-acetylserine


organism: Streptomyces lavendulae

substrate_name: OAS


enzyme_display_name: protein farnesyltransferase

substrate_name: CVIM substrate and for farnesyl transferase activity


substrate_name: L-aspartate


substrate_name: aspartate for the asparte aminotransferase activity


organism: Comamonas testosteroni


organism: Klebsiella pneumoniae

substrate_name: tryptophan (at pH 7.4 and 10 mM KMTB)


organism: Mus musculus


organism: Petunia hybrida

substrate_name: prephenate (with 20 mM aspartate as cosubstrate)


organism: Pinus pinaster

substrate_name: aspartate


organism: Pseudomonas sp


organism: Rattus norvegicus

substrate_name: L-cysteine


organism: Saccharomyces cerevisiae

substrate_name: orotidine 5'-phosphate


substrate_name: 5-Fluoroorotidine 5'-phosphate


enzyme_display_name: hypoxanthine phosphoribosyltransferase

organism: Homo sapiens

substrate_name: IMP


substrate_name: hypoxanthine


organism: Agrobacterium sp. (strain CP4)

substrate_name: phosphoenolpyruvate


organism: Escherichia coli (strain K12)

substrate_name: S3P (at pH 7 and 25 degrees Celsius)


organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

substrate_name: PEP (with 100 mM ammonium at pH 7 and 25 degrees Celsius)


substrate_name: FPP (at pH 7.5 and at 25 degrees Celsius)


organism: Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)

substrate_name: FPP


organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: O(3)-acetyl-L-serine (in the presence of 1 mM sodium sulfide at pH 6.7 and 60 degrees Celsius)


organism: Arabidopsis thaliana

substrate_name: O(3)-acetyl-L-serine for the cysteine synthase activity


organism: Methanothermobacter thermautotrophicus


substrate_name: Orotidine 5'-phosphate


organism: Baliospermum montanum


substrate_name: Undecanal


substrate_name: piperonal


substrate_name: Benzaldehyde; Cyanide


substrate_name: benzaldehyde


substrate_name: Isophthaldehyde


substrate_name: Heptanal


substrate_name: Terephthalaldehyde


substrate_name: Mandelonitrile


substrate_name: 1-naphthalene carboxaldehyde


substrate_name: 2-thiophene carboxaldehyde


substrate_name: (R)-mandelonitrile


substrate_name: 5-Fluoroorotidine 5'-phosphate


enzyme_display_name: phosphoenolpyruvate carboxykinase (GTP)

organism: Ascaris suum

substrate_name: Phosphoenolpyruvate; IDP; CO2


organism: Gallus gallus

substrate_name: Phosphoenolpyruvate; CO2; IDP


substrate_name: CO2; Phosphoenolpyruvate; GDP


organism: Mus musculus

substrate_name: ITP; Oxaloacetate


organism: Mycobacterium smegmatis


substrate_name: GTP; Oxaloacetate


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


substrate_name: IMP


substrate_name: p-nitrophenyl phosphate (at pH 5.4 and 37 degrees Celsius)


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: pNPP (at 76 degrees Celsius)


enzyme_display_name: alpha-amylase

organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: maltose (at pH 6.8 and 37 degrees Celsius)


enzyme_display_name: alpha-glucosidase

organism: Erwinia rhapontici

substrate_name: maltose


organism: Homo sapiens

substrate_name: maltoheptaose (with ctMGAM)


substrate_name: p-nitrophenyl-alpha-D-glucopyranoside


enzyme_display_name: alpha-galactosidase

organism: Bacillus subtilis (strain 168)

substrate_name: melibiose


organism: Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / LMG 10263 / NCTC 9343 / Onslow / VPI 2553 / EN-2)

substrate_name: Galalpha-pNP


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)


organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40)

substrate_name: birch wood xylan


enzyme_display_name: versatile peroxidase

organism: Amycolatopsis sp.

substrate_name: H2O2; Reactive black 5


organism: Phanerochaete chrysosporium

substrate_name: H2O2; 2,6-Dimethoxyphenol


organism: Pleurotus eryngii


substrate_name: Reactive black 5


organism: Rhodococcus jostii


enzyme_display_name: dye decolorizing peroxidase

substrate_name: H2O2; Reactive blue 5


organism: Auricularia auricula-judae


enzyme_display_name: acetate kinase

organism: Methanosarcina thermophila

substrate_name: ATP


substrate_name: veratrylglycerol-beta-guaiacyl ether


substrate_name: Reactive Blue 19


organism: Dictyostelium discoideum

substrate_name: pyrogallol


substrate_name: Reactive Blue 4


organism: Irpex lacteus


substrate_name: acetate


substrate_name: manganese


substrate_name: 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) (Dye-decolorizing peroxidase AauDyP1, at pH 4.5)


organism: Exidia glandulosa


organism: Mycena epipterygia


organism: Mycetinis scorodonius


enzyme_display_name: catalase peroxidase

organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

substrate_name: H(2)O(2) for the catalase reaction (at pH 5.5-6.0)


organism: Burkholderia pseudomallei (strain K96243)


organism: Escherichia coli (strain K12)


organism: Geobacillus stearothermophilus


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: H(2)O(2) for the catalase reaction


organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)


organism: Homo sapiens


organism: Medicago sativa subsp. varia

substrate_name: pNP-beta-D-xlyoside (at 37 degrees Celsius)


organism: Streptomyces lividans

substrate_name: p-nitrophenyl alpha-L-arabinofuranoside (pNP-Araf) (at 60 degrees Celsius and at pH 6)


substrate_name: wheat arabinoxylan (at 55 degrees Celsius)


organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40)

substrate_name: birch wood xylan


organism: Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936)

substrate_name: Unknown


organism: Humicola insolens

substrate_name: birchwood xylan


substrate_name: beechwood xylan


organism: Paenibacillus sp. (strain JDR-2)


organism: Streptomyces sp


substrate_name: 2-methoxy-5-methyl-1,4-benzoquinone (reaction performed in 20 mM Tris (pH 7.0))


enzyme_display_name: flavin-containing monooxygenase

substrate_name: trimethylamine (at pH 8.5)


organism: Macaca mulatta

substrate_name: N,N-dimethylaniline


organism: Oryctolagus cuniculus

substrate_name: thiourea


organism: Rattus norvegicus


enzyme_display_name: formate dehydrogenase

organism: Arabidopsis thaliana

substrate_name: formate(at pH 7 and 30 degrees Celsius)


organism: Candida boidinii

substrate_name: formate (at 30 degrees Celsius and at pH 7.5)


enzyme_display_name: (3R)-2'-hydroxyisoflavanone reductase

organism: Medicago sativa

substrate_name: vestitone


enzyme_display_name: citrate synthase (unknown stereospecificity)

organism: Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)

substrate_name: propionyl-CoA


organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

substrate_name: propionyl-CoA (in the presence of 1 mM oxaloacetate)


organism: Escherichia coli (strain K12)

substrate_name: oxaloacetate (at pH 8 and 35 degrees Celsius)


organism: Fusarium solani


organism: Gibberella moniliformis


organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)

substrate_name: acetyl-CoA


organism: Yarrowia lipolytica (strain CLIB 122 / E 150)


enzyme_display_name: thymidine kinase

organism: Dictyostelium discoideum

substrate_name: thymidine


organism: Homo sapiens


organism: Mus musculus


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: ATP


organism: Vaccinia virus (strain Western Reserve)


enzyme_display_name: aryl sulfotransferase

organism: Bos taurus


organism: Canis lupus familiaris


organism: Gallus gallus


organism: Amycolatopsis sp. (strain ATCC 39116 / 75iv2)

substrate_name: ABTS


organism: Thermobifida fusca (strain YX)

substrate_name: Reactive Blue 19


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: H(2)O(2) in the catalase reaction (at pH 7.0)


organism: Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

substrate_name: H(2)O(2) for the catalase reaction


substrate_name: H(2)O(2) for the catalase reaction (at pH 5.25)


substrate_name: NADPH


substrate_name: hypotaurine (at pH 8.5 and 37 degrees Celsius)


organism: Pseudomonas sp. (strain 101)

substrate_name: formate


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


organism: Thermochaetoides thermophila (strain DSM 1495 / CBS 144.50 / DAOM 24625 / IMI 039719)

substrate_name: formate (at pH 5.0 and 25 degrees Celsius)


enzyme_display_name: thymidylate synthase

organism: Escherichia coli (strain K12)

substrate_name: dUMP


enzyme_display_name: beta-fructofuranosidase

organism: Schwanniomyces occidentalis

substrate_name: sucrose


organism: Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)

substrate_name: wheat arabinoxylan (at 37 degrees Celsius and at pH 7)


organism: Arabidopsis thaliana

substrate_name: p-nitrophenyl-beta-D-xylopyranoside


substrate_name: p-nitrophenyl-beta-D-xylopyranoside (at 37 degrees Celsius)


organism: Aspergillus kawachii (strain NBRC 4308)

substrate_name: L-arabinofuranose


organism: Bacillus subtilis (strain 168)

substrate_name: sugar beet arabinan (branched)


organism: Bifidobacterium longum

substrate_name: p-nitrophenyl alpha-L-arabinofuranoside (pNP-Araf)(at pH 6 and 45 degrees Celsius)


organism: Humicola insolens

substrate_name: pNPX


substrate_name: pNPAf


enzyme_display_name: aspartate transaminase

substrate_name: L-aspartate


organism: Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)

substrate_name: oxaloacetate


organism: Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)


substrate_name: aspartate


organism: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)


organism: Rhizobium meliloti (strain 1021)


organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: L-aspartate (at 45 degrees Celsius)


substrate_name: deoxyuridine


organism: Homo sapiens

substrate_name: thymidine


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: acetate


organism: Rhodobacter capsulatus

substrate_name: H(2)O(2) for the catalase reaction (at pH 5.5-6.0)


organism: Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805)

substrate_name: H(2)O(2) for catalase activity


enzyme_display_name: unspecific peroxygenase

organism: Cyclocybe aegerita

substrate_name: ABTS (at pH 4.5)


enzyme_display_name: tetracenomycin-F1 monooxygenase

organism: Streptomyces glaucescens

substrate_name: tetracenomycin F1


enzyme_display_name: procollagen-proline 4-dioxygenase

organism: Arabidopsis thaliana


organism: Mus musculus


substrate_name: oxaloacetate (with propionyl-CoA)


organism: Thermosulfidibacter takaii (strain DSM 17441 / JCM 13301 / NBRC 103674 / ABI70S6)

substrate_name: citrate


enzyme_display_name: hypoxanthine phosphoribosyltransferase

organism: Dictyostelium discoideum

substrate_name: hypoxanthine


organism: Escherichia coli (strain K12)

substrate_name: hypoxanthine (at pH 8.5 and 25 degrees Celsius)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: guanine (at pH 7.4 and 25 degrees Celsius)


organism: Petunia hybrida

substrate_name: phosphoenolpyruvate


enzyme_display_name: cysteine synthase

substrate_name: O(3)-acetyl-L-serine for the cysteine synthase activity


organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)

substrate_name: O-succinyl-L-serine


enzyme_display_name: protein farnesyltransferase

substrate_name: CVIM substrate


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: farnesyl diphosphate


substrate_name: L-aspartate


enzyme_display_name: acetate kinase


enzyme_display_name: adenylate kinase

substrate_name: AMP


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: AMP (at 25 degrees Celsius and pH 6 or pH 7.4)


substrate_name: AMP (at 25 degrees Celsius and pH 7.6)


substrate_name: ATP (for adenylate kinase activity)


organism: Schistosoma mansoni

substrate_name: AMP (at pH 7.4)


organism: Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

substrate_name: nicotinamide mononucleotide


organism: Homo sapiens

substrate_name: NMN


substrate_name: nicotinamide mononucleotide (NMN)


organism: Caenorhabditis elegans

substrate_name: bisphenol A (at 25 degrees Celsius and pH 6.8)


organism: Mycoplasmopsis agalactiae (strain NCTC 10123 / CIP 59.7 / PG2)


organism: Methanosarcina thermophila

substrate_name: acetate


substrate_name: ATP


enzyme_display_name: alpha-glucosidase

organism: Culex quinquefasciatus

substrate_name: sucrose


enzyme_display_name: alpha-galactosidase

organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)

substrate_name: p-nitrophenyl alpha-galactoside (at pH 6.0 and 37 degrees Celsius)


organism: Geobacillus stearothermophilus

substrate_name: p-nitrophenyl-alpha-galactopyranoside (at 25 degrees Celsius and pH 6.5)


organism: Mediterraneibacter gnavus

substrate_name: p-nitrophenyl-alpha-D-galactopyranoside (at pH 6.0 and 37 degrees Celsius)


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: p-nitrophenol-alpha-galactoside (at pH 5.0 and 75 degrees Celsius)


organism: Bacillus subtilis (strain 168)

substrate_name: linear alpha-1,5-L-arabinan (at pH 6.6 and 37 degrees Celsius)


organism: Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153)

substrate_name: L- Araf-alpha-PNP


substrate_name: L-Araf-alpha-PNP


organism: Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)

substrate_name: larch arabinogalactan


organism: Cellvibrio japonicus (strain Ueda107)

substrate_name: arabinan


organism: Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)


organism: Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

substrate_name: p-nitrophenyl-alpha-L-arabinofuranoside


organism: Xylanibacter ruminicola (strain ATCC 19189 / DSM 19721 / CIP 105475 / JCM 8958 / 23)

substrate_name: pNP-beta-D-xylopyranoside (pNPX) (at 37 degrees Celsius and pH 5.0)


organism: Botrytis cinerea (strain B05.10)

substrate_name: low viscosity xylan


organism: Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)

substrate_name: wheat flour arabinoxylan


substrate_name: xylan


organism: Hypocrea rufa

substrate_name: xylan at 20 degrees Celsius


organism: Neocallimastix patriciarum

substrate_name: birchwood xylan for endo-1,4-beta-xylanase activity


substrate_name: oat spelt xylan


organism: Paenibacillus barcinonensis

substrate_name: beechwood xylan


organism: Methanosarcina thermophila

substrate_name: ATP


substrate_name: acetate


enzyme_display_name: subtilisin

organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide at 20 degrees Celsius and pH 7.5


enzyme_display_name: flavivirin

organism: Dengue virus type 2 (strain Thailand/NGS-C/1944)

substrate_name: triphosphorylated RNA


enzyme_display_name: penicillin amidase

organism: Lysinibacillus sphaericus

substrate_name: penicillin V


enzyme_display_name: arginase

organism: Arabidopsis thaliana

substrate_name: agmatine


organism: Bacillus caldovelox

substrate_name: arginine (at pH 9.5 and at 55 degrees Celsius)


organism: Oryza sativa subsp. indica

substrate_name: L-arginine


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: L-arginine (at pH 8 and 37 degrees Celsius)


organism: Schistosoma mansoni

substrate_name: arginine (at pH 9.7 and at 37 degrees Celsius)


enzyme_display_name: orotidine-5'-phosphate decarboxylase

organism: Homo sapiens

substrate_name: orotidine 5'-phosphate


enzyme_display_name: phosphoenolpyruvate carboxykinase (GTP)

substrate_name: phosphoenolpyruvate


substrate_name: oxaloacetate (for the enzyme purified from cells exposed to 10 mM glucose)


organism: Rattus norvegicus

substrate_name: oxaloacetate


organism: Penicillium oxalicum

substrate_name: birchwood xylan


organism: Phanerodontia chrysosporium


organism: Rhizopus oryzae


organism: Talaromyces funiculosus


organism: Trichoderma reesei (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / VTT-D-86271 / Rut C-30)

substrate_name: beechwood (unsubstituted) xylan


enzyme_display_name: peptidyl-dipeptidase A

substrate_name: Hip-His-Leu


organism: Bacillus licheniformis


organism: Methanosarcina thermophila


substrate_name: ATP


enzyme_display_name: glycine hydroxymethyltransferase

organism: Escherichia coli

substrate_name: tetrahydrofolate


substrate_name: acetate


substrate_name: L-Ser


organism: Sus scrofa


enzyme_display_name: (S)-hydroxynitrile lyase

organism: Hevea brasiliensis


organism: Manihot esculenta


enzyme_display_name: tryptophan synthase

organism: Zea mays

substrate_name: indole-3-glycerol phosphate


enzyme_display_name: thymidine kinase

substrate_name: thymidine


organism: Penicillium griseofulvum

substrate_name: wheat arabinoxylan


enzyme_display_name: citrate synthase (unknown stereospecificity)

substrate_name: acetyl-CoA


enzyme_display_name: beta-fructofuranosidase

organism: Schwanniomyces occidentalis

substrate_name: nystose


substrate_name: inulin


enzyme_display_name: alkaline phosphatase

organism: Vibrio splendidus

substrate_name: 4-nitrophenyl phosphate


enzyme_display_name: sulfite oxidase

organism: Homo sapiens

substrate_name: sulfite


enzyme_display_name: branched-chain-amino-acid transaminase

substrate_name: L-leucine


substrate_name: L-glutamate


enzyme_display_name: alpha-galactosidase


enzyme_display_name: dihydrolipoyl dehydrogenase

organism: Leishmania donovani

substrate_name: dihydrolipoamide


substrate_name: NAD+


substrate_name: glyoxylate


substrate_name: beta-D-fructose 6-phosphate

mutation_signature: C-terminal deletion mutant L307


mutation_signature: C-terminal deletion mutant A305


mutation_signature: C-terminal deletion mutant Y306


enzyme_display_name: acetate kinase

substrate_name: ATP


substrate_name: propionate


organism: Helicobacter pylori

substrate_name: L-arginine


mutation_signature: C-terminal deletion mutant D299


substrate_name: Butyrate


enzyme_display_name: unspecific peroxygenase

organism: Thermothelomyces thermophilus


organism: Arthrobacter sp.


substrate_name: propionyl-CoA


organism: Thermoplasma acidophilum


substrate_name: citrate


substrate_name: acetyl-CoA


organism: Bacillus subtilis

substrate_name: phosphoenolpyruvate


substrate_name: shikimate 3-phosphate


enzyme_display_name: arginase

organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)

substrate_name: L-arginine (at pH 7.5 and 37 degrees Celsius)


organism: Glaciozyma antarctica (strain PI12)


organism: Rattus norvegicus

substrate_name: arginine


organism: Mycolicibacterium smegmatis

substrate_name: OAA (PEP forming activity at pH 7.2 and 37 degrees Celsius)


organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: oxaloacetate (at 60 degrees Celsius)


organism: Escherichia coli


organism: Streptomyces sp

substrate_name: Unknown


organism: Talaromyces funiculosus


organism: Thermomyces lanuginosus


organism: Drosophila melanogaster

substrate_name: angiotensin I


substrate_name: Hip-His-Leu


organism: Oryctolagus cuniculus


enzyme_display_name: subtilisin

organism: Bacillus subtilis subsp. natto

substrate_name: Suc-Ala-Ala-Pro-Phe-pNA


organism: Plasmodium falciparum

substrate_name: PEP1 (Ac-LVSADNIDIS) peptide


enzyme_display_name: flavivirin

organism: Dengue virus type 2 (strain Puerto Rico/PR159-S1/1969)

substrate_name: N-acetyl-Gly-Arg-Arg-AMC


organism: Kokobera virus

substrate_name: ATPase of serine protease NS3


organism: Tick-borne encephalitis virus European subtype (strain Neudoerfl)

substrate_name: ATP


enzyme_display_name: penicillin amidase

organism: Bacillus subtilis (strain 168)

substrate_name: penicillin V


organism: Caenorhabditis elegans


substrate_name: deoxycytidine


substrate_name: thymidine


organism: Bambusa oldhamii

substrate_name: sucrose


enzyme_display_name: catalase peroxidase

organism: Mycobacterium tuberculosis


enzyme_display_name: thymidylate synthase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: dUMP


enzyme_display_name: glycine hydroxymethyltransferase

organism: Arabidopsis thaliana

substrate_name: H4PteGlu1 (at pH 8.5)


organism: Bombyx mori

substrate_name: L-serine (at pH 3.0 and 30 degrees Celsius)


organism: Escherichia coli (strain K12)

substrate_name: L-serine


organism: Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)

substrate_name: L-serine (at pH 7.5 and 70 degrees Celsius)


organism: Methanosarcina barkeri (strain Fusaro / DSM 804)

substrate_name: tetrahydrofolate (at pH 7.2 and 37 degrees Celsius)


organism: Plasmodium falciparum (isolate 3D7)


enzyme_display_name: glutaminyl-peptide cyclotransferase


organism: Drosophila melanogaster

substrate_name: H-Gln-Gly-OH (at 30 degrees Celsius)


organism: Ixodes scapularis

substrate_name: L-glutaminyl 2-naphthylamide (Gln-beta-NA) (in the presence of Zn(2+), at 25 degrees Celsius)


enzyme_display_name: citrate synthase (unknown stereospecificity)

organism: Antarctic bacterium DS2-3R

substrate_name: oxaloacetate (with propionyl-CoA at pH 8 and 23 degrees Celsius)


enzyme_display_name: dye decolorizing peroxidase

organism: Thermomonospora curvata


substrate_name: Reactive Blue 19


substrate_name: Reactive Blue 4


substrate_name: guaiacol


substrate_name: hydroquinone


organism: Bacillus pumilus


substrate_name: peroxyacetic acid


organism: Burkholderia pseudomallei


enzyme_display_name: flavin-containing monooxygenase

organism: Homo sapiens

substrate_name: tamoxifen


substrate_name: clomiphene


organism: Methylophaga aminisulfidivorans

substrate_name: indole


organism: Rattus norvegicus

substrate_name: NADPH; L-Selenomethionine; O2; H+


substrate_name: NADPH; L-Methionine; O2; H+


organism: Escherichia coli


organism: Mycobacterium smegmatis


organism: Mycobacterium tuberculosis

substrate_name: o-Dianisidine


organism: Synechococcus elongatus

substrate_name: isoniazid


organism: Agrocybe aegerita

substrate_name: H2O2; Veratryl alcohol


organism: Chaetomium globosum

substrate_name: testosterone


organism: Coprinus radians

substrate_name: H2O2; Benzyl alcohol


organism: Cyclocybe aegerita

substrate_name: veratryl alcohol


substrate_name: benzyl alcohol


organism: Marasmius rotula

substrate_name: trans-stilbene


organism: Sulfurisphaera tokodaii

substrate_name: ethylbenzene


enzyme_display_name: procollagen-proline 4-dioxygenase

organism: Arabidopsis thaliana

substrate_name: L-Proline; O2; 2-Oxoglutarate


organism: Gallus gallus

substrate_name: O2; 2-Oxoglutarate; (Pro-Pro-Gly)10


substrate_name: O2; (Pro-Pro-Gly)5; 2-Oxoglutarate


substrate_name: NADH


substrate_name: NADPH; H+; O2; Trimethylamine


substrate_name: Benzydamine


substrate_name: clomiphene


substrate_name: Cyclohexane


organism: Irpex lacteus


substrate_name: Reactive Blue 19


organism: Pleurotus sapidus


substrate_name: Reactive Blue 5


substrate_name: isophorone


substrate_name: Cyclohexanol


organism: Hypoxylon sp. EC38


substrate_name: indole


substrate_name: 3,4-dimethoxybenzyl alcohol


enzyme_display_name: formate dehydrogenase

organism: [Candida] methylica

substrate_name: formate


organism: Clostridium carboxidivorans


organism: Cupriavidus necator


organism: Lotus japonicus


organism: Arthrobacter sp.

substrate_name: oxaloacetate


substrate_name: Acetyl-CoA


organism: Aspergillus nidulans

substrate_name: acetyl-CoA


organism: Aspergillus niger


organism: Bacillus subtilis

substrate_name: H2O; Acetyl-CoA; Oxaloacetate


organism: Escherichia coli


organism: Xanthomonas campestris


organism: Acinetobacter calcoaceticus (subsp. anitratus)


organism: Methanobacterium formicicum

substrate_name: Coenzyme F420; Formate


organism: Moraxella sp.


organism: Ogataea angusta


organism: Pseudomonas sp. 101

substrate_name: NAD+


organism: Thermochaetoides thermophila


organism: Thermothelomyces thermophilus

substrate_name: NADH


organism: Homo sapiens

substrate_name: Gln-Gln


organism: Sus scrofa

substrate_name: NADPH; H+; O2; Trimethylamine


organism: Arabidopsis thaliana


organism: Bacillus sp. (in: Bacteria)


substrate_name: NADP+


organism: Candida boidinii

substrate_name: NAD+; Formate


organism: [Candida] boidinii


organism: [Candida] methylica


organism: Microcystis aeruginosa


organism: Nostoc sp. PCC 7120 = FACHB-418


organism: Saccharolobus solfataricus


organism: Saccharomyces cerevisiae


organism: Streptomyces diastaticus


organism: Synechocystis sp. PCC 6803


organism: Escherichia coli


organism: Fasciola hepatica


organism: Geobacter sulfurreducens


organism: Halobacterium volcanii


organism: Haloferax volcanii


organism: Helicobacter pylori


organism: Metallosphaera sedula


enzyme_display_name: thymidine kinase

organism: Homo sapiens

substrate_name: ATP; Thymidine


substrate_name: thymidine


organism: Human alphaherpesvirus 1


organism: Human herpesvirus 1

substrate_name: Ganciclovir


substrate_name: acyclovir


organism: Staphylococcus aureus


organism: Thermotoga maritima


substrate_name: ATP


substrate_name: ATP; Deoxythymidine


organism: Epstein-Barr virus

substrate_name: CTP


substrate_name: dTTP


organism: Gallus gallus


substrate_name: oxaloacetate


substrate_name: acetyl-CoA


organism: Thermoplasma acidophilum


organism: Thermosulfidibacter takaii

substrate_name: H2O; Acetyl-CoA; Oxaloacetate


organism: Anolis carolinensis


organism: Arabidopsis thaliana

substrate_name: deoxyuridine


organism: Bacillus cereus


organism: Caenorhabditis elegans


organism: Danio rerio


organism: Dictyostelium discoideum


organism: Entamoeba histolytica


substrate_name: GTP


organism: Vaccinia virus


substrate_name: Deoxythymidine; ATP


organism: Xenopus tropicalis


enzyme_display_name: aryl sulfotransferase

organism: Bos taurus

substrate_name: Unknown


organism: Homo sapiens


substrate_name: 3'-Phosphoadenylyl sulfate; Dopamine


organism: Leishmania major


substrate_name: uridine


organism: Mus musculus

substrate_name: deoxycytidine


substrate_name: ATP; 1-beta-D-Arabinofuranosylthymine


substrate_name: ATP; Thymidine


organism: Rattus norvegicus


organism: Saccharolobus solfataricus

substrate_name: delta-undecanolactone


substrate_name: paraoxon


substrate_name: gamma-undecanolactone


substrate_name: N-(3-oxodecanoyl)-L-homoserine lactone


substrate_name: gamma-heptanolactone


substrate_name: gamma-nonalactone


substrate_name: N-(3-oxohexanoyl)-L-homoserine lactone


substrate_name: gamma-dodecanolactone


substrate_name: N-(3-oxooctanoyl)-L-homoserine lactone


substrate_name: epsilon-caprolactone


substrate_name: N-hexanoylhomoserine lactone


substrate_name: delta-nonalactone


enzyme_display_name: beta-fructofuranosidase

substrate_name: Sucrose


substrate_name: H2O; Sucrose


substrate_name: delta-valerolactone


substrate_name: N-octanoylhomoserine lactone


substrate_name: dihydrocoumarin


substrate_name: N-(3-Oxooctanoyl)homoserine lactone


substrate_name: N-dodecanoylhomoserine lactone


substrate_name: delta-undecanolactone


substrate_name: N-(3-oxohexanoyl)homoserine lactone


organism: Sulfolobus acidocaldarius


substrate_name: gamma-heptanolide