substrate_name: glyoxylate


organism: Vitis vinifera

substrate_name: Unknown

source_db: uniprot

verification_status: unverified

kcat_display: Not reported

km_display: Not reported

ki_display: Not reported

kcat_over_km_display: Not reported

mutation_signature: Unknown

protein_accession_database: UniProt

source_license: CC BY 4.0


enzyme_display_name: hydroxypyruvate reductase

organism: Rattus norvegicus

substrate_name: 3-Hydroxypyruvate; NADH; H+

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)

km_unit: mM


organism: Escherichia coli

substrate_name: NADPH; H+; 3-Hydroxypyruvate

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: 3-Hydroxypyruvate; NADPH; H+


organism: Hyphomicrobium methylovorum

substrate_name: NADH; 3-Hydroxypyruvate; H+


organism: Blautia hydrogenotrophica

substrate_name: NAD+; Glycerate


enzyme_display_name: malate dehydrogenase (NADP+)

organism: Methanocaldococcus jannaschii

substrate_name: NADPH; Oxaloacetate


organism: Methanothermus fervidus


organism: Sorghum bicolor

substrate_name: Oxaloacetate; NADPH; H+


organism: Pisum sativum

substrate_name: H+; NADPH; Oxaloacetate


organism: Zea mays

substrate_name: NADPH; Oxaloacetate; H+


organism: Spinacia oleracea

substrate_name: NADP+; L-Malate


organism: Glycine max


substrate_name: D-Malate; NAD+


enzyme_display_name: Tartrate dehydrogenase/decarboxylase

organism: Pseudomonas putida

substrate_name: NAD(+) (for (+)-tartrate oxidation)


enzyme_display_name: 3-isopropylmalate dehydrogenase

substrate_name: 3-Isopropylmalate; NAD+


organism: Thermus thermophilus


organism: Sulfurisphaera tokodaii

source_db: brenda

source_license: CC BY 4.0; CC BY-NC-ND 4.0


enzyme_display_name: 3-isopropylmalate dehydrogenase 2, chloroplastic

organism: Arabidopsis thaliana


enzyme_display_name: 3-isopropylmalate dehydrogenase 1, chloroplastic


enzyme_display_name: 3-isopropylmalate dehydrogenase 3, chloroplastic


enzyme_display_name: ketol-acid reductoisomerase

substrate_name: H+; 3-Hydroxypyruvate; NADPH


enzyme_display_name: ketol-acid reductoisomerase (NADP+)

organism: Corynebacterium glutamicum


organism: Streptomyces viridifaciens


organism: Streptomyces avermitilis


organism: Streptomyces ambofaciens


ki_unit: mM


enzyme_display_name: Ketol-acid reductoisomerase (NADP(+))

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


enzyme_display_name: homoisocitrate dehydrogenase

substrate_name: Homoisocitrate; NAD+


organism: Saccharomyces cerevisiae

substrate_name: (2R,3S)-3-(4-pentenyl)malic acid


enzyme_display_name: Homoisocitrate dehydrogenase

organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


enzyme_display_name: hydroxymethylglutaryl-CoA reductase

organism: Pseudomonas mevalonii

substrate_name: NAD+; Coenzyme A; Mevalonate


enzyme_display_name: aryl-alcohol dehydrogenase

organism: Lactobacillus plantarum

substrate_name: Benzyl alcohol; NAD+


enzyme_display_name: aryl-alcohol dehydrogenase (NADP+)

organism: Phanerodontia chrysosporium

substrate_name: Unknown


enzyme_display_name: aryl-alcohol dehydrogenase (NADP(+))

organism: Ralstonia sp.

substrate_name: NADP+

source_db: oed

kcat_over_km_origin: calculated


enzyme_display_name: tartrate dehydrogenase

organism: Sus scrofa

substrate_name: meso-Tartrate; NAD+


substrate_name: NAD+; meso-Tartrate


substrate_name: isopropylmalate


organism: Escherichia coli

substrate_name: sn-glycerol 3-phosphate


substrate_name: NAD(P)+


organism: Escherichia coli (strain K12)


enzyme_display_name: phosphoglycerate dehydrogenase

substrate_name: 3-Phospho-D-glycerate; NAD+


substrate_name: H+; 3-Phosphohydroxypyruvate; NADH


organism: Homo sapiens

substrate_name: NADH; H+; 3-Phosphohydroxypyruvate

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


substrate_name: NAD+; 3-Phospho-D-glycerate


organism: Streptomyces coelicolor


organism: Mycobacterium tuberculosis


organism: Sulfurisphaera tokodaii


substrate_name: Acetoacetyl-CoA; H+; NADPH


organism: Persea americana

substrate_name: acetoacetyl-[acyl-carrier protein]


enzyme_display_name: Fatty acid synthase

organism: Rattus norvegicus


substrate_name: beta-ketododecanoyl-CoA (at 25 degrees Celsius and at pH 7.0)


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: beta-keto-octanoyl-CoA


enzyme_display_name: acylglycerone-phosphate reductase

organism: Mus musculus

substrate_name: 1-O-Hexadecyl glycerone phosphate; NADPH; H+


substrate_name: NADPH; H+; 1-O-Hexadecyl glycerone phosphate


organism: Saccharomyces cerevisiae

substrate_name: 1-O-Hexadecyl glycerone phosphate; NADPH


organism: Candida albicans (strain SC5314 / ATCC MYA-2876)

substrate_name: C18-3-oxosphinganine (at pH 6.9)


enzyme_display_name: L-threonine 3-dehydrogenase

substrate_name: NAD+; L-Threonine


organism: Flavobacterium frigidimaris

substrate_name: L-Threonine; NAD+


organism: Pyrococcus horikoshii


organism: Cytophaga sp.

substrate_name: Unknown


substrate_name: L-threonine


organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)


enzyme_display_name: Dehydrogenase/reductase SDR family member 6


enzyme_display_name: retinol dehydrogenase

substrate_name: NADPH; H+; all-trans-Retinal

verification_status: corrected


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: NADH tested with dihydrotestosterone


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH7

substrate_name: 12-OH-dodecanoic acid (with 0.1 M sodium phosphate at pH 7.5)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase 13


enzyme_display_name: pyridoxal 4-dehydrogenase

organism: Microbacterium luteolum

substrate_name: NAD+; Pyridoxal


enzyme_display_name: carnitine 3-dehydrogenase

organism: Rhizobium sp. (Cicer)

substrate_name: NAD+; L-Carnitine


organism: Xanthomonas translucens

substrate_name: L-Carnitine; NAD+


enzyme_display_name: L-carnitine dehydrogenase

organism: Pseudomonas sp

substrate_name: L-carnithine


enzyme_display_name: Aromatic 2-oxoacid reductase

organism: Clostridium sporogenes (strain ATCC 15579)

substrate_name: phenyllactate


enzyme_display_name: indanol dehydrogenase

organism: Homo sapiens

substrate_name: Indan-1-ol; NADP+


substrate_name: NADP+; Indan-1-ol


enzyme_display_name: D-arabinose 1-dehydrogenase

substrate_name: NAD+; D-Arabinose


enzyme_display_name: glucose 1-dehydrogenase (NADP+)

organism: Halobacterium volcanii

substrate_name: D-Glucose; NADP+


enzyme_display_name: Glucose 1-dehydrogenase

organism: Gluconobacter oxydans (strain 621H)


organism: Saccharolobus solfataricus

substrate_name: D-glucose (in the presence of NAD(+), at 70 degrees Celsius and pH 8)


enzyme_display_name: L-arabinose 1-dehydrogenase (NAD(P)(+))

organism: Azospirillum brasilense

substrate_name: L-arabinose (in the presence of NAD(+), at 30 degrees Celsius and pH 9.0)


enzyme_display_name: UniProt Q5SLC4

organism: Thermus thermophilus HB8

source_db: skid

verification_status: verified

source_license: CC BY-NC-ND 4.0


enzyme_display_name: L-fucose dehydrogenase

substrate_name: L-fuctose


enzyme_display_name: D-threo-aldose 1-dehydrogenase

substrate_name: Unknown


organism: Rattus norvegicus


organism: Oryctolagus cuniculus


enzyme_display_name: GDP-mannose 6-dehydrogenase

organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


enzyme_display_name: dTDP-4-dehydrorhamnose reductase

organism: Salmonella typhimurium


organism: Aneurinibacillus thermoaerophilus


organism: Pseudomonas aeruginosa

substrate_name: UDP-GlcNAc (refolded enzyme, in the presence of NAD(+))


substrate_name: UDP-D-GlcNAc


enzyme_display_name: mannitol 2-dehydrogenase (NADP+)

organism: Alternaria alternata

substrate_name: H+; D-Fructose; NADPH


enzyme_display_name: UniProt P28845


substrate_name: dehydroepiandrosterone


substrate_name: NAD+


organism: Solanum lycopersicum

substrate_name: pregnenolone


substrate_name: dehydrotomatidine


organism: Digitalis lanata

substrate_name: NADH


organism: Rhinella arenarum


organism: Bufo gargarizans


enzyme_display_name: 16alpha-hydroxysteroid dehydrogenase

organism: Rattus sp.

substrate_name: NADPH


organism: Cricetinae


enzyme_display_name: perillyl-alcohol dehydrogenase

organism: Acinetobacter calcoaceticus

substrate_name: perillyl alcohol


organism: Pseudomonas sp.


organism: Homo sapiens


enzyme_display_name: 11beta-hydroxysteroid dehydrogenase

substrate_name: cortisol


organism: Comamonas testosteroni


organism: Clarias gariepinus


enzyme_display_name: Geraniol dehydrogenase

organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen)

substrate_name: geraniol


substrate_name: (S)-perillyl alcohol


substrate_name: citronellol


substrate_name: cumic alcohol


substrate_name: benzyl alcohol


substrate_name: prostaglandin E1


substrate_name: prostaglandin A1


substrate_name: prostaglandin A2


substrate_name: NAD in the presence of prostaglandin E1


substrate_name: dehydroepiandrosterone


substrate_name: NAD+


organism: Mesocricetus auratus


substrate_name: corticosterone


enzyme_display_name: Alcohol dehydrogenase 2

organism: Tanacetum cinerariifolium

substrate_name: trans-chrysanthemol


substrate_name: NAD(+)


substrate_name: prostaglandin E2


organism: Cavia porcellus


substrate_name: cortisone


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

organism: Rattus norvegicus

substrate_name: dihydrotestosterone (in the presence of NADPH)


organism: Mycobacterium tuberculosis


substrate_name: Prostaglandin E2


substrate_name: NADP+


enzyme_display_name: sorbitol-6-phosphate 2-dehydrogenase

organism: Erwinia amylovora

substrate_name: D-fructose 6-phosphate


substrate_name: D-sorbitol 6-phosphate


substrate_name: NADH


substrate_name: D-Fructose 6-phosphate


organism: Klebsiella aerogenes


substrate_name: sorbitol 6-phosphate


enzyme_display_name: 11-beta-hydroxysteroid dehydrogenase 1


substrate_name: pregnenolone


organism: Mus musculus


substrate_name: cortisol


substrate_name: Cortisol


substrate_name: dehydroepiandrosterone


organism: Saimiri sciureus


substrate_name: corticosterone


substrate_name: dihydrotestosterone (in the presence of NADH)


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2


enzyme_display_name: UniProt A7A7R9

organism: Bifidobacterium adolescentis


enzyme_display_name: 20alpha-hydroxysteroid dehydrogenase

organism: Tetrahymena thermophila


substrate_name: ethyl acetoacetate


substrate_name: acetoacetyl-CoA


substrate_name: ethyl pyruvate


substrate_name: ethyl 4-chloroacetoacetate


substrate_name: isatin


substrate_name: methyl acetoacetate


substrate_name: ethyl 3-oxovalerate


substrate_name: acetoin


substrate_name: ethyl benzoylacetate


substrate_name: methylglyoxal


substrate_name: Phenylglyoxal


substrate_name: D-glyceraldehyde


substrate_name: D-Lactaldehyde


substrate_name: DL-glyceraldehyde 3-phosphate


substrate_name: (S)-ethyl 3-hydroxybutyrate


substrate_name: n-octyl acetoacetate


substrate_name: NADPH


substrate_name: n-hexyl acetoacetate


substrate_name: n-butyl acetoacetate


substrate_name: benzyl acetoacetate


substrate_name: NADP+


substrate_name: ethyl 2-methylacetoacetate


substrate_name: (S)-methyl 3-hydroxybutyrate


enzyme_display_name: estradiol 17alpha-dehydrogenase

organism: Oryctolagus cuniculus

substrate_name: Epitestosterone


substrate_name: 17alpha-estradiol 3-glucuronide


organism: Chlorobaculum tepidum


substrate_name: sepiapterin


substrate_name: diacetyl


organism: Eubacterium sp.


enzyme_display_name: ureidoglycolate dehydrogenase [NAD(P)+]

organism: Arthrobacter allantoicus


substrate_name: NAD+


substrate_name: (R,S)-ureidoglycolate


organism: Sus scrofa


substrate_name: NADH


enzyme_display_name: 21-hydroxysteroid dehydrogenase (NAD+)

organism: Ovis aries aries


enzyme_display_name: 21-hydroxysteroid dehydrogenase (NADP+)


organism: Gallus gallus


organism: Equus caballus


organism: Bos taurus


organism: Ovis aries

substrate_name: NADH; 21-Dehydrocortisone; H+


substrate_name: 21-Dehydrocortisone; H+; NADPH


organism: Rattus norvegicus


substrate_name: D,L-glyceraldehyde


substrate_name: NADPH


substrate_name: progesterone


organism: Homo sapiens


substrate_name: cortisol


substrate_name: (S)-tetralol


enzyme_display_name: UniProt Q04828


enzyme_display_name: Aldo-keto reductase family 1 member C1


organism: Tetrahymena pyriformis


substrate_name: NADP+


substrate_name: testosterone (oxidation)


enzyme_display_name: Sepiapterin reductase


substrate_name: dihydrotestosterone


substrate_name: thionicotinamide adenine dinucleotide phosphate


substrate_name: 3-acetylpyridine adenine dinucleotide phosphate


organism: [Clostridium] scindens


substrate_name: all-trans-retinal


substrate_name: estrone


substrate_name: ketotifen


substrate_name: isocaproaldehyde


substrate_name: beta-ionol


substrate_name: befunolol


substrate_name: methylglyoxal


substrate_name: menadione


substrate_name: pyridine 3-aldehyde


substrate_name: isatin


substrate_name: dehydroepiandrosterone


substrate_name: diacetyl


substrate_name: D-glyceraldehyde


substrate_name: ethyl 3-oxovalerate


substrate_name: D-Lactaldehyde


substrate_name: ethyl benzoylacetate


substrate_name: (S)-ethyl 3-hydroxybutyrate


substrate_name: DL-glyceraldehyde 3-phosphate


substrate_name: hexanal


substrate_name: alpha-tetralone


substrate_name: testosterone


substrate_name: dehydroepiandrosterone 3-sulfate


substrate_name: acetoin


substrate_name: Estrone 3-sulfate


substrate_name: n-octyl acetoacetate


substrate_name: n-hexyl acetoacetate


substrate_name: n-butyl acetoacetate


substrate_name: benzyl acetoacetate


substrate_name: ethyl 2-methylacetoacetate


substrate_name: ethyl acetoacetate


substrate_name: acetoacetyl-CoA


substrate_name: ethyl pyruvate


substrate_name: ethyl 4-chloroacetoacetate


substrate_name: isatin


substrate_name: methyl acetoacetate


substrate_name: (S)-methyl 3-hydroxybutyrate


substrate_name: progesterone


substrate_name: Nonanal


substrate_name: geraniol


substrate_name: acrolein


substrate_name: cortisone


substrate_name: cortisol


enzyme_display_name: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)

substrate_name: NADPH


substrate_name: Sepiapterin


organism: Mus musculus


organism: Dictyostelium discoideum

substrate_name: sepiapterin


substrate_name: Progesterone


substrate_name: Camphorquinone


substrate_name: Phenylglyoxal


substrate_name: benzene dihydrodiol


enzyme_display_name: UniProt G9FRD7

organism: Clostridium sardiniense

substrate_name: chenodeoxycholic acid


substrate_name: NADP+


enzyme_display_name: glycerol 2-dehydrogenase (NADP+)

organism: Dunaliella parva


substrate_name: dihydroxyacetone


substrate_name: glycerol


enzyme_display_name: 7alpha-hydroxysteroid dehydrogenase


organism: Brevibacterium fuscum

substrate_name: cholic acid


substrate_name: NADH


substrate_name: NAD+


substrate_name: 12-oxolithocholic acid


substrate_name: Dehydrocholic acid


substrate_name: 7,12-Diketolithocholic acid


organism: Phycomyces blakesleeanus

substrate_name: NADPH


organism: Schizosaccharomyces pombe


enzyme_display_name: 3-hydroxybutyryl-CoA dehydrogenase

organism: Clostridium kluyveri


enzyme_display_name: erythrulose reductase


substrate_name: D-erythrulose


organism: Gluconobacter oxydans


organism: Clostridium acetobutylicum


organism: Stenotrophomonas maltophilia


organism: Bacteroides fragilis


organism: Escherichia coli (strain K12)

substrate_name: NAD(+)


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 7.0 and 25 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: isoursodeoxycholic acid (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: dehydrocorticosterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of beta-hydroxybutyryl-CoA, at pH 9.3 and 25 degrees Celsius)


substrate_name: tetramyristoyl cardiolipin


substrate_name: tetralinoleoyl cardiolipin


substrate_name: chenodeoxycholic acid


substrate_name: cholic acid


substrate_name: NADP+


substrate_name: taurochenodeoxycholate


substrate_name: chenodeoxycholate


substrate_name: cholate


substrate_name: glycocholate


substrate_name: taurocholate


organism: Trichoderma reesei

substrate_name: NADPH


substrate_name: dihydroxyacetone


substrate_name: glycerol


enzyme_display_name: glycerol 2-dehydrogenase (NADP(+))

substrate_name: methylglyoxal


substrate_name: Acetoin


substrate_name: D-Glyceraldehyde


substrate_name: Dihydroxyacetone


substrate_name: Dimethylglyoxal


substrate_name: Glyoxal


enzyme_display_name: Glycerol 2-dehydrogenase (NADP(+))

organism: Hypocrea jecorina

substrate_name: D-glyceraldehyde


substrate_name: diacetyl


substrate_name: glyoxal


substrate_name: acetoin


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: D,L-glyceraldehyde


substrate_name: p-nitrobenzaldehyde


substrate_name: benzaldehyde


substrate_name: phenylglyoxal


substrate_name: acrolein


substrate_name: butyraldehyde


substrate_name: L-Glyceraldehyde


substrate_name: NADP+


organism: Gallus gallus

substrate_name: ethyl pyruvate


substrate_name: Phenanthrenequinone


substrate_name: D-erythrulose


substrate_name: isatin


substrate_name: Methyl pyruvate


organism: Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / LMG 10263 / NCTC 9343 / Onslow / VPI 2553 / EN-2)

substrate_name: cholate (at pH 8.5)


substrate_name: chenodeoxycholate (at pH 8.5)


substrate_name: glycocholate (at pH 8.5)


substrate_name: glycochenodeoxycholate (at pH 8.5)


substrate_name: taurocholate (at pH 8.5)


substrate_name: taurochenodeoxycholate (at pH 8.5)


substrate_name: 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate (at pH 6.5)


substrate_name: NADH (in the presence of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate, at pH 8.5)


enzyme_display_name: UniProt A0A0J9X283

organism: Staphylococcus aureus

substrate_name: NADPH


organism: Clostridium sardiniense

substrate_name: chenodeoxycholic acid


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: NAD (at pH 9.5 and at 30 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (at pH 9.5 and at 30 degrees Celsius)


substrate_name: NADH (at pH 9.5 and at 30 degrees Celsius)


substrate_name: acetoacetyl-CoA (at pH 9.5 and at 30 degrees Celsius)


substrate_name: NADH


organism: Saccharomyces cerevisiae


substrate_name: isatin


substrate_name: dl-camphorquinone


substrate_name: beta-naphthoquinone


substrate_name: ninhydrin


substrate_name: alloxan


organism: Lactiplantibacillus plantarum

substrate_name: NAD+


substrate_name: (-)-Dihydroshikimate


substrate_name: (-)-shikimate


substrate_name: (-)-quinate


organism: Candida parapsilosis


substrate_name: ketopantoyl lactone


organism: Spinacia oleracea


substrate_name: bornanedione


enzyme_display_name: hexadecanol dehydrogenase

organism: Acinetobacter sp.

substrate_name: hexadecanol


enzyme_display_name: 2-alkyn-1-ol dehydrogenase

organism: Fusarium merismoides


substrate_name: chenodeoxycholic acid


substrate_name: cholic acid


organism: Lactobacillus plantarum


organism: Candida orthopsilosis


substrate_name: NADPH


organism: Candida dubliniensis


enzyme_display_name: 2-dehydropantoate 2-reductase

organism: Escherichia coli


organism: Thermococcus kodakarensis


substrate_name: (R)-pantoate


substrate_name: NADH


organism: Escherichia coli (strain K12)

substrate_name: pantoate


substrate_name: NADP(+)


organism: Homo sapiens


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


enzyme_display_name: UniProt P0A9J4


enzyme_display_name: 12alpha-hydroxysteroid dehydrogenase

organism: [Clostridium] scindens


substrate_name: 12-oxolithocholic acid


substrate_name: NADP+


substrate_name: deoxycholic acid


organism: Archaeoglobus fulgidus


substrate_name: L-alpha-glycerol 3-phosphate


substrate_name: D-glyceraldehyde 3-phosphate


organism: Peptacetobacter hiranonis


enzyme_display_name: 2-oxoadipate reductase


organism: [Clostridium] hylemonae


organism: Eggerthella sp. CAG:298

substrate_name: 12-oxo-deoxycholic acid


enzyme_display_name: L-rhamnose 1-dehydrogenase

organism: Aureobasidium pullulans

substrate_name: NAD+


substrate_name: L-rhamnose


organism: Eggerthella lenta


enzyme_display_name: D-xylose 1-dehydrogenase

organism: Arthrobacter sp.

substrate_name: D-xylose


organism: Debaryomyces hansenii


enzyme_display_name: D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)

organism: Haloarcula marismortui

substrate_name: D-glucose


organism: Bifidobacterium sp.


organism: Clostridium perfringens


organism: [Clostridium] leptum


substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 7.0 and 25 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: isoursodeoxycholic acid (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: dehydrocorticosterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of beta-hydroxybutyryl-CoA, at pH 9.3 and 25 degrees Celsius)


organism: Scheffersomyces stipitis

substrate_name: L-Lyxose


substrate_name: L-Mannose


organism: Macaca fuscata

substrate_name: NADPH


substrate_name: NADP+


substrate_name: Camphorquinone


organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)

substrate_name: D-xylose (at pH 9)


substrate_name: NAD(+) (at pH 9)


organism: Paenarthrobacter nicotinovorans

substrate_name: NAD+


substrate_name: D-xylose


enzyme_display_name: D-xylose dehydrogenase

substrate_name: NADP(+)


organism: Homo sapiens


substrate_name: tetramyristoyl cardiolipin


substrate_name: tetralinoleoyl cardiolipin


substrate_name: L-rhamnose


organism: Macaca fuscata fuscata

substrate_name: naphthalene dihydrodiol (at pH 10.0)


substrate_name: benzene dihydrodiol (at pH 10.0)


substrate_name: 3-deoxyglucosone (at pH 7.5)


substrate_name: methylglyoxal (at pH 7.5)


substrate_name: D-glucose (at pH 7.5)


organism: Clostridium sp. (strain ATCC 29733 / VPI C48-50)

substrate_name: NADP(+) (at pH 8.0 and 25 degrees Celsius)


substrate_name: cholate (at pH 8.0 and 25 degrees Celsius)


substrate_name: deoxycholate (at pH 8.0 and 25 degrees Celsius)


substrate_name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate (12-oxochenodeoxycholate) (at pH 8.0 and 25 degrees Celsius)


organism: Clostridium sp.

substrate_name: 12-oxochenodeoxycholic acid


substrate_name: NADPH


substrate_name: NADP+


substrate_name: deoxycholic acid


substrate_name: cholic acid


organism: Canis lupus familiaris

substrate_name: naphthalene dihydrodiol (at pH 7.5)


substrate_name: benzene dihydrodiol (at pH 7.5)


substrate_name: D-xylose


substrate_name: camphorquinone (at pH 7.5)


enzyme_display_name: D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)

substrate_name: D-glucose


substrate_name: D-ribose


substrate_name: D-Xylose


organism: Trichoderma reesei

substrate_name: D-Arabinose


substrate_name: D-Galactose


substrate_name: D-Glucose


substrate_name: D-Ribose


substrate_name: L-Arabinose


enzyme_display_name: D-xylose 1-dehydrogenase (NADP(+))

organism: Hypocrea jecorina (strain ATCC 56765 / BCRC 32924 / NRRL 11460 / Rut C-30)

substrate_name: NADP(+)


substrate_name: D-arabinose


organism: Sus scrofa


organism: Caulobacter vibrioides

substrate_name: NAD+


organism: Pseudomonas putida


organism: Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)

substrate_name: NAD


substrate_name: D-xylose (at pH 7.5)


organism: Arthrobacter nicotinovorans


substrate_name: NADP+


enzyme_display_name: D-xylose 1-dehydrogenase (NADP(+)) 2

organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)


substrate_name: NADP


substrate_name: Camphorquinone


substrate_name: D-xylose


organism: Oryctolagus cuniculus


enzyme_display_name: geraniol dehydrogenase (NADP(+))

organism: Zingiber officinale

substrate_name: geraniol


substrate_name: nerol


enzyme_display_name: carbonyl reductase (NADPH)

organism: Bacillus subtilis

substrate_name: NADPH


substrate_name: ethyl 4-chloroacetoacetate


enzyme_display_name: UniProt B2KJ46

organism: Candida parapsilosis


substrate_name: NADH


enzyme_display_name: UniProt F1N9C1

organism: Gallus gallus

substrate_name: testosterone


substrate_name: estrone


substrate_name: prostaglandin E2


substrate_name: acetone


substrate_name: p-toluquinone


substrate_name: menadione


substrate_name: isatin


enzyme_display_name: UniProt P16152

organism: Homo sapiens


enzyme_display_name: UniProt Q28960


enzyme_display_name: UniProt Q5FQJ0

organism: Gluconobacter oxydans

substrate_name: methylglyoxal


enzyme_display_name: UniProt Q9X265

organism: Thermotoga maritima

substrate_name: ethyl 2-methylacetoacetate


substrate_name: ethyl 2-oxo-4-phenylbutyrate


enzyme_display_name: UniProt Q9Y8Y1

organism: Aeropyrum pernix


substrate_name: ethyl 4-chloro-3-oxobutanoate


substrate_name: doxorubicin


substrate_name: oracin


organism: Methanobacterium palustre

substrate_name: acetoin


substrate_name: NADP+


substrate_name: diacetyl


substrate_name: Cyclohexanol


substrate_name: Cycloheptanone


substrate_name: Cyclopentanone


substrate_name: cyclohexanone


substrate_name: Cyclopentanol


substrate_name: propanone


substrate_name: NADPH


organism: Starmerella magnoliae


substrate_name: ethyl 2-chloro-3-oxobutanoate


substrate_name: methyl 4-chloro-3-oxobutanoate


substrate_name: ketopantoyl lactone


substrate_name: ethyl pyruvate


substrate_name: methyl 2-chloro-3-oxobutanoate


substrate_name: ethyl 2-oxobutanoate


enzyme_display_name: geraniol dehydrogenase (NADP+)

organism: Cymbopogon flexuosus

substrate_name: geranial


substrate_name: geraniol


substrate_name: NADP+


organism: Persicaria minor


substrate_name: cinnamyl alcohol


substrate_name: linalool


substrate_name: NADH


mutation_signature: deletion mutant lacking 31 N-terminal amino acids


substrate_name: NADPH; 4-Oxonon-2-enal


substrate_name: 4-Oxonon-2-enal; NADPH


substrate_name: menadione


organism: Mus musculus

substrate_name: doxorubicin


substrate_name: methylglyoxal


substrate_name: NADPH


substrate_name: Phenylglyoxal


enzyme_display_name: L-glycol dehydrogenase

organism: Klebsiella aerogenes


substrate_name: diacetyl


substrate_name: ethyl pyruvate


substrate_name: ethyl 4-chloro-3-oxobutanoate


substrate_name: p-toluquinone


enzyme_display_name: GDP-4-dehydro-D-rhamnose reductase

organism: Pseudomonas sp.


substrate_name: Unknown


substrate_name: ethyl 2-oxo-4-phenylbutyrate


substrate_name: ethyl 2-methylacetoacetate


substrate_name: 7alpha-Hydroxycholesterol; NAD+


substrate_name: glyceraldehyde


substrate_name: Glyoxal


substrate_name: acetoin


substrate_name: NADH


substrate_name: nerol


substrate_name: NADP+


substrate_name: menadione


organism: Citrus sp.

substrate_name: geraniol


substrate_name: NADPH


organism: Kluyveromyces marxianus

substrate_name: methyl glyoxal


substrate_name: diacetyl


organism: Pichia kudriavzevii

substrate_name: ethyl 2-oxo-4-phenylbutanoate


organism: [Candida] boidinii


organism: Candida parapsilosis


enzyme_display_name: Dehydrogenase/reductase SDR family member 4

organism: Oryctolagus cuniculus

substrate_name: 16-Ketoestrone (at pH6)


substrate_name: all-trans-Retinal (at pH7.4)


substrate_name: Isatin (at pH6)


substrate_name: Propiophenone (at pH6)


substrate_name: Heptanophenone (at pH6)


substrate_name: Nonanophenone (at pH6)


substrate_name: 4-Hexanoylpyridine (at pH6)


substrate_name: Hexanophenone (at pH6)


substrate_name: Valerophenone (at pH6)


substrate_name: n-Butyrophenone (at pH6)


substrate_name: 3-Benzoylpyridine (at pH6)


substrate_name: 4-Benzoylpyridine (at pH6)


substrate_name: 2,3-Hexanedione (at pH6)


substrate_name: 1-phenyl-1,2-propanedione (at pH6)


substrate_name: Benzil (at pH6)


substrate_name: Diacetyl (at pH6)


substrate_name: Pyridine-4-aldehyde (at pH6)


substrate_name: 1-Phenylisatin (at pH6)


substrate_name: 9,10-Phenanthrenequinone (at pH6)


substrate_name: Menadione (at pH6)


substrate_name: S-(-)-1-Phenyl-1-butanol (at pH7.4)


substrate_name: all-trans-Retinol (at pH7.4)


organism: Bacillus cereus

substrate_name: ethyl 4-chloroacetoacetate


organism: Carpoglyphus lactis

substrate_name: geraniol


substrate_name: NAD+


enzyme_display_name: UniProt Q8WNV7

organism: Sus scrofa


substrate_name: 16-Ketoestrone (at pH6)


substrate_name: all-trans-Retinal (at pH7.4)


substrate_name: isatin (at pH6)


substrate_name: Propiophenone (at pH6)


substrate_name: Heptanophenone (at pH6)


substrate_name: Nonanophenone (at pH6)


substrate_name: 4-Hexanoylpyridine (at pH6)


substrate_name: Hexanophenone (at pH6)


substrate_name: Valerophenone (at pH6)


substrate_name: n-Butyrophenone (at pH6)


substrate_name: 3-Benzoylpyridine (at pH6)


substrate_name: 4-Benzoylpyridine (at pH6)


substrate_name: 2,3-Hexanedione (at pH6)


substrate_name: 1-phenyl-1,2-propanedione (at pH6)


substrate_name: Benzil (at pH6)


substrate_name: Diacetyl (at pH6)


substrate_name: Pyridine-4-aldehyde (at pH6)


substrate_name: 1-Phenylisatin (at pH6)


substrate_name: Menadione (at pH6)


substrate_name: S-(-)-1-Phenyl-1-butanol (at pH7.4)


substrate_name: all-trans-Retinol (at pH7.4)


organism: Homo sapiens

substrate_name: Isatin (at pH6)


substrate_name: 5beta-Androstane-3,17-dione (at pH7.4)


substrate_name: 5alpha-Dihydrotestosterone (at pH7.4)


substrate_name: Dehydrolithocholic acid (at pH7.4)


substrate_name: all-trans-Retinal (at pH7.4)


substrate_name: 4-Hexanoylpyridine (at pH6)


substrate_name: Hexanophenone (at pH6)


substrate_name: Valerophenone (at pH6)


substrate_name: n-Butyrophenone (at pH6)


substrate_name: 4-Benzoylpyridine (at pH6)


substrate_name: 3,4-hexanedione (at pH6)


substrate_name: 2,3-heptanedione (at pH6)


substrate_name: 4,4'-Dimethylbenzil (at pH6)


substrate_name: 2,3-Pentanedione (at pH6)


substrate_name: Diacetyl (at pH6)


substrate_name: 4-Nitrobenzaldehyde (at pH6)


substrate_name: Pyridine-4-aldehyde (at pH6)


substrate_name: 1,4-Naphthoquinone (at pH6)


substrate_name: 5b-Pregnan-3b-ol-20-one (at pH7.4)


substrate_name: 5b-Androstane-3b,17b-diol (at pH7.4)


substrate_name: 5b-Androstan-3b-ol-17-one (at pH7.4)


substrate_name: menadione


enzyme_display_name: Carbonyl reductase [NADPH] 1

substrate_name: prostaglandin E2


substrate_name: NADPH


enzyme_display_name: Aldo/keto reductase slr0942

organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)

substrate_name: hexanal


substrate_name: furfural


enzyme_display_name: Carbonyl reductase [NADPH] 3


substrate_name: isatin


substrate_name: oracin


substrate_name: methylglyoxal


substrate_name: glyoxal


substrate_name: acrolein


substrate_name: 5beta-Pregnane-3,20-dione(at pH7.4)


substrate_name: Benzil (at pH6)


substrate_name: 1-Phenylisatin (at pH6)


substrate_name: 9,10-Phenanthrenequinone (at pH7.4)


substrate_name: Menadione (at pH6)


substrate_name: doxorubicin


substrate_name: 5alpha-Pregnane-3,20-dione (at pH7.4)


substrate_name: Dehydrolithocholic acid (at pH7.4)


substrate_name: 2,3-Pentanedione (at pH6)


substrate_name: Methyl benzoylformate (at pH6)


substrate_name: 4-Nitrobenzaldehyde (at pH6)


substrate_name: menadione


substrate_name: NADPH


substrate_name: 5beta-Pregnane-3,20-dione (at pH7.4)


substrate_name: 4-Acetylpyridine (at pH6)


substrate_name: Pyridine-3-aldehyde (at pH6)


substrate_name: 4-Nitroacetophenone (at pH6)


organism: Rattus norvegicus


substrate_name: NAD+


substrate_name: NADH


substrate_name: NADP+


substrate_name: Daunorubicin


organism: Ocimum basilicum

substrate_name: geraniol


enzyme_display_name: geraniol dehydrogenase (NADP(+))

substrate_name: Geraniol


substrate_name: Nerol


substrate_name: cinnamyl alcohol


enzyme_display_name: Geraniol dehydrogenase 1


substrate_name: daunorubicin


enzyme_display_name: carbonyl reductase (NADPH)

substrate_name: Prostaglandin E2


substrate_name: prostaglandin E2


substrate_name: menadiol


substrate_name: Adriamycin


substrate_name: isatin


substrate_name: menadione


substrate_name: oracin


substrate_name: prostaglandin E1


substrate_name: phenylglyoxal


substrate_name: NADPH


substrate_name: S-nitrosoglutathione


substrate_name: S-Nitrosoglutathione


organism: Caenorhabditis elegans

substrate_name: Isatin


substrate_name: isatin (at 25 degrees Celsius)


organism: Mesocricetus auratus


substrate_name: NAD+


substrate_name: p-Nitrobenzaldehyde


enzyme_display_name: UniProt P15121

substrate_name: prostaglandin H2


enzyme_display_name: UniProt C5XC49

organism: Sorghum bicolor

substrate_name: coniferyl aldehyde


substrate_name: sinapyl aldehyde


substrate_name: coniferyl alcohol


enzyme_display_name: cinnamyl-alcohol dehydrogenase

organism: Helicobacter pylori

substrate_name: benzaldehyde


substrate_name: butanol


substrate_name: ethanol


substrate_name: cinnamyl aldehyde


substrate_name: benzyl alcohol


substrate_name: Propanol


substrate_name: cinnamyl alcohol


substrate_name: NADP+


substrate_name: acetaldehyde


substrate_name: NADPH


enzyme_display_name: long-chain-alcohol dehydrogenase

organism: Pseudomonas putida

substrate_name: n-butanol


substrate_name: n-Propanol


substrate_name: n-decanal


substrate_name: n-Hexanol


substrate_name: NADH


substrate_name: n-Pentanol


substrate_name: n-decanol


substrate_name: n-Heptanol


substrate_name: NAD+


substrate_name: n-Octanol


substrate_name: n-nonanol


organism: Glycine max

substrate_name: coniferaldehyde


substrate_name: cinnamaldehyde


substrate_name: sinapaldehyde


substrate_name: p-coumaraldehyde


substrate_name: coniferyl alcohol


substrate_name: 3,4-dimethoxycinnamyl alcohol


substrate_name: cinnamyl alcohol


substrate_name: sinapyl alcohol


substrate_name: p-coumaryl alcohol


organism: Petroselinum crispum


substrate_name: benzaldehyde


organism: Amycolatopsis methanolica


substrate_name: 12-Hydroxydodecanoic acid


substrate_name: ethanol


organism: Micrococcus luteus

substrate_name: 12-hydroxyoctadecanoic acid


substrate_name: 10-hydroxyoctadecanoic acid


substrate_name: 10,12-dihydroxyoctadecanoic acid


organism: Phaseolus vulgaris

substrate_name: coniferyl aldehyde


substrate_name: sinapyl aldehyde


substrate_name: benzyl alcohol


organism: Geobacillus thermodenitrificans

substrate_name: NAD+


substrate_name: NADP+


substrate_name: NADPH


enzyme_display_name: coniferyl-alcohol dehydrogenase

organism: Streptomyces sp.

substrate_name: coniferyl alcohol


organism: Oryza sativa Japonica Group

substrate_name: 4-coumaryl aldehyde


organism: Plagiochasma appendiculatum


substrate_name: caffeylaldehyde


organism: Hibiscus cannabinus

substrate_name: cinnamaldehyde


substrate_name: cinnamyl aldehyde


substrate_name: coniferaldehyde


organism: Carthamus tinctorius


organism: Populus tomentosa


substrate_name: sinapaldehyde


organism: Forsythia suspensa


substrate_name: 4-methoxycinnamyl alcohol


substrate_name: 3,4-dimethoxy-cinnamyl alcohol


substrate_name: p-coumaryl alcohol


substrate_name: cinnamyl alcohol


organism: Pinus thunbergii


substrate_name: p-coumaraldehyde


enzyme_display_name: indole-3-acetaldehyde reductase (NADPH)

organism: Brassica rapa subsp. pekinensis


substrate_name: phenylacetaldehyde


substrate_name: acetaldehyde


substrate_name: NAD+


substrate_name: allyl alcohol


organism: Phycomyces blakesleeanus

substrate_name: NADPH


substrate_name: dihydroxyacetone phosphate


organism: Geobacillus stearothermophilus


substrate_name: NADH


enzyme_display_name: prostaglandin-F synthase

organism: Mus musculus

substrate_name: 9alpha,11beta-prostaglandin F2


substrate_name: Prostaglandin D2


organism: Populus x canadensis


organism: Rattus norvegicus


substrate_name: Unknown


organism: Nostoc sp.


substrate_name: (2S)-5-hydroxy-2-aminovaleric acid


organism: Saccharum officinarum

substrate_name: sinapyl alcohol


substrate_name: coniferyl alcohol


organism: Glycine max

substrate_name: NADP+


substrate_name: sinapyl aldehyde


substrate_name: coniferyl aldehyde


organism: Trypanosoma brucei


substrate_name: prostaglandin H2


substrate_name: testosterone


organism: Synechocystis sp.

substrate_name: cinnamyl alcohol


substrate_name: cinnamaldehyde


organism: Oryctolagus cuniculus


organism: Saccharomyces cerevisiae


enzyme_display_name: indole-3-acetaldehyde reductase (NADH)

organism: Cucumis sativus


substrate_name: hexadecanol


organism: Artemisia annua

substrate_name: 4-coumaryl aldehyde


organism: Sus scrofa


enzyme_display_name: Long-chain-alcohol dehydrogenase 1

organism: Geobacillus thermodenitrificans (strain NG80-2)

substrate_name: ethanol


substrate_name: acetaldehyde


substrate_name: NAD


substrate_name: NADH


substrate_name: NADP


enzyme_display_name: Long-chain-alcohol dehydrogenase 2


substrate_name: octanal


organism: Oryza sativa Japonica Group


substrate_name: cinnamyl aldehyde


organism: Bos taurus

substrate_name: Hydrindantin


substrate_name: Prostaglandin D3


substrate_name: prostaglandin D1


substrate_name: Prostaglandin D2


substrate_name: p-nitroacetophenone


substrate_name: Phenylglyoxal


substrate_name: cyclohexanone


substrate_name: DL-glyceraldehyde


organism: Medicago truncatula

substrate_name: sinapyl aldehyde


substrate_name: coniferyl aldehyde


substrate_name: p-coumaryl aldehyde


substrate_name: prostaglandin E2


substrate_name: menadione


substrate_name: NADPH


organism: Sorghum bicolor


enzyme_display_name: Aldo-keto reductase family 1 member C3

organism: Homo sapiens


substrate_name: testosterone (oxidation)


substrate_name: prostaglandin H2


organism: Sinopodophyllum hexandrum

substrate_name: sinapaldehyde


substrate_name: coniferaldehyde


substrate_name: Prostaglandin A2


substrate_name: progesterone


substrate_name: androstanediol


enzyme_display_name: Riboflavin biosynthesis protein PYRR, chloroplastic

organism: Zea mays


organism: Arabidopsis thaliana


substrate_name: Caffeic aldehyde


substrate_name: Coniferaldehyde


enzyme_display_name: Cinnamyl alcohol dehydrogenase 5

substrate_name: 4-coumaraldehyde (at pH 6.25-6.5 and 30 degrees Celsius)


substrate_name: caffeyl aldehyde (at pH 6.0-6.25 and 30-35 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.0-6.25 and 30-35 degrees Celsius)


substrate_name: 5-hydroxyconiferaldehyde (at pH 6.25-6.5 and 30 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.0-6.25 and 30-35 degrees Celsius)


enzyme_display_name: Cinnamyl alcohol dehydrogenase 3

substrate_name: 4-coumaraldehyde (at pH 6.25 and 40 degrees Celsius)


substrate_name: caffeyl aldehyde (at pH 6.25 and 40 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.25 and 40 degrees Celsius)


substrate_name: 5-hydroxyconiferaldehyde (at pH 6.25 and 37 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.25 and 40 degrees Celsius)


enzyme_display_name: Cinnamyl alcohol dehydrogenase 2

substrate_name: 4-coumaraldehyde (at pH 6.5 and 40 degrees Celsius)


substrate_name: caffeyl aldehyde (at pH 6.25-6.5 and 40 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.5 and 40 degrees Celsius)


substrate_name: 5-hydroxyconiferaldehyde (at pH 6.5 and 37 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.5 and 40 degrees Celsius)


enzyme_display_name: Cinnamyl alcohol dehydrogenase 4

substrate_name: 4-coumaraldehyde (at pH 6.25-6.5 and 35 degrees Celsius)


substrate_name: caffeyl aldehyde (at pH 6.25 and 30 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.25-6.5 and 35 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.25-6.5 and 30 degrees Celsius)


substrate_name: Coniferaldehyde


substrate_name: Sinapoyl aldehyde


substrate_name: 4-Hydroxycinnamyl aldehyde


enzyme_display_name: Cinnamyl alcohol dehydrogenase 7

substrate_name: 4-coumaraldehyde (at pH 6.25-6.5 and 30 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.25 and 30 degrees Celsius)


substrate_name: 5-hydroxyconiferaldehyde (at pH 6.25 and 30 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.25 and 30 degrees Celsius)


enzyme_display_name: Cinnamyl alcohol dehydrogenase 8

substrate_name: 4-coumaraldehyde (at pH 6.25 and 42 degrees Celsius)


substrate_name: caffeyl aldehyde (at pH 6.0 and 35 degrees Celsius)


substrate_name: coniferaldehyde (at pH 6.25 and 42 degrees Celsius)


substrate_name: 5-hydroxyconiferaldehyde (at pH 6.25 and 42 degrees Celsius)


substrate_name: sinapaldehyde (at pH 6.25-6.5 and 25 degrees Celsius)


substrate_name: Prostaglandin D2


substrate_name: Prostaglandin H2


organism: Leucaena leucocephala

substrate_name: cinnamaldehyde


substrate_name: cinnamyl alcohol


substrate_name: coniferyl alcohol


substrate_name: coniferyl aldehyde


substrate_name: NADP+


substrate_name: NADPH


substrate_name: p-coumaryl aldehyde


substrate_name: sinapyl alcohol


substrate_name: sinapyl aldehyde


organism: Aralia cordata


organism: Populus tremuloides

substrate_name: Coniferaldehyde


substrate_name: Sinapoyl aldehyde


substrate_name: 4-coumaryl aldehyde


organism: Ocimum basilicum

substrate_name: Geraniol


enzyme_display_name: Cinnamyl alcohol dehydrogenase 1


substrate_name: geraniol


enzyme_display_name: Carbonyl reductase [NADPH] 1

substrate_name: prostaglandin E1


substrate_name: phenylglyoxal


substrate_name: Prostaglandin D2


enzyme_display_name: cinnamyl-alcohol dehydrogenase


organism: Escherichia coli


substrate_name: NADH


substrate_name: 9alpha,11beta-Prostaglandin F2


organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)

substrate_name: NADP


substrate_name: NAD


substrate_name: menadione


substrate_name: daunorubicin


organism: Oryza sativa


substrate_name: NADPH


organism: Rattus norvegicus


substrate_name: prostaglandin E2


substrate_name: retinal


enzyme_display_name: prostaglandin-E2 9-reductase


substrate_name: D-xylose


organism: Trypanosoma brucei

substrate_name: Prostaglandin H2


substrate_name: S-nitrosoglutathione


enzyme_display_name: 7alpha-hydroxysteroid dehydrogenase

organism: Pseudomonas sp.

substrate_name: cholic acid


enzyme_display_name: aldose-6-phosphate reductase (NADPH)

organism: Malus domestica


enzyme_display_name: 1,3-propanediol dehydrogenase

organism: Klebsiella pneumoniae


substrate_name: acetaldehyde


substrate_name: Butyraldehyde


substrate_name: formaldehyde


substrate_name: NAD+


substrate_name: NADH


substrate_name: propionaldehyde


substrate_name: Valeraldehyde


enzyme_display_name: UniProt Q1QUN7

organism: Chromohalobacter salexigens

substrate_name: beta-D-glucuronate


enzyme_display_name: UniProt Q7CRQ0

organism: Agrobacterium tumefaciens

substrate_name: beta-D-galacturonate


enzyme_display_name: uronate dehydrogenase

organism: Chromohalobacter israelensis


organism: [Ruminococcus] torques

substrate_name: 7-oxo-lithocholic acid


substrate_name: NADPH


organism: Penicillium camemberti


substrate_name: L-galactonate


substrate_name: L-Gulonic acid


substrate_name: D-glucuronic acid


organism: Lentilactobacillus buchneri


substrate_name: glyceraldehyde


substrate_name: glycerol


organism: Blautia producta

substrate_name: 3,7-Diketo-5beta-cholanoic acid


substrate_name: 3,7,12-Triketo-5beta-cholanoic acid


substrate_name: 3,7,12-triketo-5beta-cholanoyl taurine


enzyme_display_name: (+)-borneol dehydrogenase

organism: Pseudomonas putida

substrate_name: (+)-borneol


substrate_name: NAD+


organism: Pseudomonas sp. ATCC 17453


substrate_name: (-)-borneol


organism: Hathewaya limosa


substrate_name: NADP+


organism: Levilactobacillus brevis


organism: Thermobispora bispora

substrate_name: D-galacturonic acid


substrate_name: D-glucuronic acid from a beechwood xylan


substrate_name: NADH


organism: Oceanicola granulosus

substrate_name: beta-D-galacturonate

protein_accession_database: NCBI Protein


substrate_name: D-Mannuronate


organism: Artemisia annua

substrate_name: (-)-cis-carveol


substrate_name: (-)-artemisia alcohol


organism: Pseudomonas sp. TCU-HL1


substrate_name: Unknown


organism: Fulvimarina pelagi


organism: Streptomyces viridochromogenes


organism: Cinnamomum camphora


organism: Polaromonas naphthalenivorans


organism: Pseudomonas monteilii


organism: Ectopseudomonas mendocina


organism: Pseudomonas sp.


organism: Chromohalobacter israelensis


organism: Lavandula x intermedia


enzyme_display_name: 7beta-hydroxysteroid dehydrogenase

organism: Clostridium sardiniense

substrate_name: ursocholate


substrate_name: ursodeoxycholate


substrate_name: dehydrocholate


organism: Sus scrofa

substrate_name: prostaglandin E2


substrate_name: menadione


substrate_name: NADPH


organism: Collinsella aerofaciens (strain ATCC 25986 / DSM 3979 / JCM 10188 / KCTC 3647 / NCTC 11838 / VPI 1003)

substrate_name: NADP(+)


organism: Collinsella aerofaciens


substrate_name: Ursodeoxycholic acid


organism: Agrobacterium tumefaciens

substrate_name: D-glucuronate


substrate_name: NAD+


enzyme_display_name: Uronate dehydrogenase

organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)


substrate_name: NAD(+)


organism: Malus domestica

substrate_name: D-glucose 6-phosphate


organism: Pseudomonas putida KT2440

substrate_name: D-galacturonate


substrate_name: tauroursodeoxycholate


organism: Salvia officinalis


substrate_name: (+)-borneol


organism: Mediterraneibacter gnavus


substrate_name: 7-oxolithocholate (7-oxo-LCA) (at pH 6 and 37 degrees Celsius)


organism: Chromohalobacter salexigens

substrate_name: beta-D-glucuronate


organism: Homo sapiens


substrate_name: toluquinone


substrate_name: prostaglandin A1


organism: Klebsiella pneumoniae


substrate_name: NADH


substrate_name: NADP+


substrate_name: prostaglandin E1


substrate_name: phenylglyoxal


substrate_name: menadione


substrate_name: prostaglandin E2


substrate_name: daunorubicin


substrate_name: NADPH


organism: Citrobacter freundii


substrate_name: propionaldehyde


substrate_name: NAD(+) (with 1,3-propanediol as substrate)


substrate_name: NADH (with propionaldehyde as substrate)


organism: Oenococcus oeni

substrate_name: NAD+


organism: Prunus persica


substrate_name: D-sorbitol 6-phosphate


substrate_name: Dehydrocholic acid


substrate_name: 7-ketolithocholic acid


organism: Oryza sativa


substrate_name: D-glucose 6-phosphate


enzyme_display_name: 11-beta-hydroxysteroid dehydrogenase 1

organism: Mesocricetus auratus

substrate_name: corticosterone


organism: Rattus norvegicus


organism: Saimiri sciureus

substrate_name: cortisol


substrate_name: cortisone


organism: Mus musculus


organism: Thermobispora bispora

substrate_name: D-galacturonic acid


substrate_name: S-nitrosoglutathione


organism: Cavia porcellus


organism: Clostridium sardiniense

substrate_name: NADP+


enzyme_display_name: UniProt A0A6L8P2U9

organism: Bacillus anthracis


substrate_name: IMP


enzyme_display_name: UniProt Q756Z6

organism: Eremothecium gossypii


enzyme_display_name: UniProt Q8T6T2

organism: Cryptosporidium parvum

substrate_name: 3-acetylpyridine adenine dinucleotide


enzyme_display_name: IMP dehydrogenase

organism: Saccharomyces cerevisiae


enzyme_display_name: UniProt Q91WR5

substrate_name: lithocholic acid


enzyme_display_name: tropinone reductase I

organism: Pseudomonas sp.

substrate_name: Tropine


substrate_name: nortropine


organism: Homo sapiens

substrate_name: H2O; IMP; NAD+


substrate_name: NAD+; H2O; IMP


enzyme_display_name: UniProt A0A2R4D3F6

organism: Campylobacter jejuni

substrate_name: NAD+


enzyme_display_name: (-)-menthol dehydrogenase

organism: Mentha arvensis

substrate_name: (-)-menthol


organism: Mentha x piperita


substrate_name: (-)-menthone


enzyme_display_name: (+)-neomenthol dehydrogenase


substrate_name: NADPH


organism: Dendrobium nobile


substrate_name: tropinone


organism: Oryctolagus cuniculus

substrate_name: Epitestosterone


substrate_name: androsterone


organism: Withania somnifera


substrate_name: N-methylpiperidine


substrate_name: Unknown


organism: Chlorocebus aethiops


organism: Przewalskia tangutica


organism: Artemisia annua


substrate_name: (+)-neomenthol


organism: Tritrichomonas suis

substrate_name: inosine 5'-phosphate


enzyme_display_name: Aldo-keto reductase family 1 member C1

substrate_name: (s)-tetralol


enzyme_display_name: Aldo-keto reductase family 1 member C2


substrate_name: progesterone (reduction)


substrate_name: testosterone (oxidation)


enzyme_display_name: Aldo-keto reductase family 1 member C4


organism: Mus musculus

substrate_name: testosterone


enzyme_display_name: Aldo-keto reductase family 1 member C3


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Rattus norvegicus


substrate_name: dihydrotestosterone


substrate_name: estradiol


substrate_name: NAD


substrate_name: NADP


organism: Aspergillus nidulans

substrate_name: IMP


substrate_name: NAD+


substrate_name: NADH


substrate_name: NADPH


substrate_name: all-trans-retinol


substrate_name: allopregnanolone


substrate_name: androsterone


substrate_name: dehydroepiandrosterone


substrate_name: NADP(+)


substrate_name: allopregnanolone (oxidation)


substrate_name: (s)-tetralol (oxidation)


substrate_name: benzene dihydrodiol (oxidation)


substrate_name: prostaglandin D2 (reduction)


substrate_name: (s)-tetralol


organism: Withania coagulans

substrate_name: Tropine


substrate_name: NADP+


substrate_name: tropinone


organism: Vibrio cholerae serotype O1

substrate_name: IMP


mutation_signature: recombinant short enzyme CBS-deletion mutant VcIMPDHDELTAL


substrate_name: NAD+


organism: Macaca fuscata fuscata


organism: Penicillium brevicompactum


substrate_name: inosine 5'-phosphate


organism: Eremothecium gossypii


enzyme_display_name: UniProt P9WKI7

organism: Mycobacterium tuberculosis


organism: Homo sapiens


substrate_name: (s)-indan-1-ol (oxidation)


substrate_name: progesterone


substrate_name: androstanediol


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

substrate_name: dihydrotestosterone (in the presence of NADPH)


enzyme_display_name: NADPH-dependent 3-keto-steroid reductase Hsd3b5


organism: Arabidopsis thaliana


substrate_name: prostaglandin H2


substrate_name: progesterone (reduction)


organism: Bacillus amyloliquefaciens


substrate_name: 5alpha-androstan-3,17-dione (reduction)


substrate_name: Epitestosterone


organism: Escherichia coli


substrate_name: K+


substrate_name: testosterone


substrate_name: estrone


substrate_name: acenaphthenequinone


enzyme_display_name: Aldo-keto reductase family 1 member C21

substrate_name: NADP


substrate_name: Benzene dihydrodiol


substrate_name: p-Nitrobenzaldehyde


substrate_name: Pregnanediol


substrate_name: NAD+


organism: Datura stramonium

substrate_name: NADPH


substrate_name: tropinone


substrate_name: lithocholic acid


organism: Hyoscyamus niger


substrate_name: Tropine


substrate_name: NADH


substrate_name: IMP


organism: Cochlearia officinalis


enzyme_display_name: Tropinone reductase


substrate_name: nortropinone


substrate_name: quinuclidinone


substrate_name: epiandrosterone


substrate_name: Nicotinamide guanine dinucleotide


substrate_name: Nicotinamide hypoxanthine dinucleotide


organism: Withania somnifera

substrate_name: NADP+


substrate_name: N-methylpiperidine


enzyme_display_name: UniProt Q8T6T2

organism: Cryptosporidium parvum


enzyme_display_name: IMP dehydrogenase

substrate_name: 3-Acetylpyridine-adenine dinucleotide


enzyme_display_name: Inosine-5'-monophosphate dehydrogenase

substrate_name: Inosine 5'-phosphate


enzyme_display_name: tropinone reductase I


substrate_name: Scopine


substrate_name: nortropine


substrate_name: Nortropinone


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: allopregnanolone


substrate_name: dehydroepiandrosterone


substrate_name: androsterone


substrate_name: dihydrotestosterone


enzyme_display_name: Retinol dehydrogenase 16


substrate_name: NAD


substrate_name: NADP


substrate_name: all-trans-retinol


organism: Candida albicans

substrate_name: IMP


substrate_name: NAD+


organism: Brugmansia arborea


substrate_name: Tropine


substrate_name: tropinone


organism: Withania coagulans

substrate_name: NADP+


substrate_name: NADPH


enzyme_display_name: (+)-neomenthol dehydrogenase

organism: Capsicum annuum

substrate_name: menthone


substrate_name: neomenthol


organism: Leishmania donovani


substrate_name: Inosine 5'-phosphate


substrate_name: NAD(+)


organism: Mus musculus


substrate_name: estradiol


organism: Vigna unguiculata


substrate_name: 3-Acetylpyridine-adenine dinucleotide


substrate_name: thio-NAD+


organism: Escherichia coli (strain K12)


enzyme_display_name: Trifunctional enzyme subunit alpha, mitochondrial

organism: Homo sapiens


substrate_name: hexadecanoyl-CoA


organism: Bos taurus

substrate_name: prostaglandin D2


substrate_name: menadione


organism: Babesia gibsoni

substrate_name: Inosine 5'-diphosphate


enzyme_display_name: UniProt P0C0H6

organism: Streptococcus pyogenes

substrate_name: IMP


substrate_name: NAD+


organism: Bacillus amyloliquefaciens


organism: Tritrichomonas foetus


enzyme_display_name: UniProt P12268


organism: Pneumocystis carinii


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


organism: Toxoplasma gondii


organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)


organism: Anisodus luridus


organism: Artemisia annua

substrate_name: (-)-menthone


substrate_name: (+)-neomenthol


organism: Ovis aries

substrate_name: progesterone


organism: Candida albicans (strain SC5314 / ATCC MYA-2876)


organism: Rattus norvegicus

substrate_name: NADH


enzyme_display_name: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

organism: Mus musculus

substrate_name: estrone


organism: Schizosaccharomyces pombe

substrate_name: K+


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: inosine 5'-phosphate


organism: Borrelia burgdorferi


organism: Hyoscyamus niger

substrate_name: NADP+


substrate_name: dihydrotestosterone


enzyme_display_name: NADPH-dependent 3-keto-steroid reductase Hsd3b4


organism: Homo sapiens

substrate_name: dihydrotestosterone (in the presence of NADH)


organism: Przewalskia tangutica

substrate_name: tropinone


organism: Drosophila melanogaster

substrate_name: NADPH


enzyme_display_name: carbonyl reductase (NADPH)

organism: Gallus gallus

substrate_name: H+; NADPH; Pyridine-4-aldehyde


substrate_name: Isatin; H+; NADPH


enzyme_display_name: UniProt P52895


enzyme_display_name: gluconate 2-dehydrogenase

organism: Acetobacter ascendens


substrate_name: gluconate


enzyme_display_name: morphine 6-dehydrogenase

organism: Pseudomonas putida


organism: Mesocricetus auratus


substrate_name: glycochenodeoxycholic acid


substrate_name: lithocholic acid


substrate_name: glycolithocholic acid


substrate_name: Dehydrolithocholic acid


enzyme_display_name: farnesol dehydrogenase (NADP+)

organism: Persicaria minor


substrate_name: carveol


substrate_name: NAD+


substrate_name: (S)-perillyl alcohol


substrate_name: nerodilol


substrate_name: cinnamyl alcohol


substrate_name: geraniol


substrate_name: NADP+


substrate_name: diacetyl


substrate_name: isatin


organism: Cavia porcellus

substrate_name: Morphine; NAD+


substrate_name: nalorphine


substrate_name: codeine


substrate_name: normorphine


substrate_name: morphine


substrate_name: ethylmorphine


substrate_name: Dihydrocodeine


substrate_name: androsterone


organism: Eggerthella sp. CAG:298

substrate_name: 3-oxo-deoxycholic acid


substrate_name: deoxycholic acid


substrate_name: 3-oxodeoxycholic acid


substrate_name: isodeoxycholic acid


substrate_name: NADH


substrate_name: NAD+


organism: Comamonas testosteroni


organism: Rattus norvegicus

substrate_name: NADPH


substrate_name: NADP+


organism: Candida dubliniensis


enzyme_display_name: dihydroflavonol 4-reductase

organism: Fragaria x ananassa

substrate_name: dihydroquercetin


substrate_name: dihydromyricetin


substrate_name: dihydrokaempferol


organism: Persea americana


substrate_name: acetoacetyl-[acyl-carrier protein]


substrate_name: acetoacetyl-CoA


organism: Komagataella phaffii


substrate_name: benzaldehyde


substrate_name: naloxone


organism: Ipomoea batatas

substrate_name: trans,trans-farnesol


substrate_name: geraniol


substrate_name: androsterone


organism: Saccharomyces cerevisiae

substrate_name: Benzyl 2-methyl-3-oxobutyrate


organism: Brevibacterium ketosoreductum


substrate_name: Prostaglandin


organism: Aspergillus niger

substrate_name: L-Idonate


organism: Plutella xylostella

substrate_name: Unknown


organism: Manduca sexta

substrate_name: farnesol


substrate_name: morphine


organism: Pseudomonas plecoglossicida

substrate_name: D-gluconate


organism: Homo sapiens


organism: Pseudotsuga menziesii

substrate_name: (+)-dihydroquercetin


organism: Cryptomeria japonica


enzyme_display_name: Aldo-keto reductase family 1 member B15

substrate_name: all-trans-retinal


substrate_name: D,L-glyceraldehyde


substrate_name: hexanal


substrate_name: acrolein


substrate_name: farnesal


substrate_name: NADPH


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: acetoacetyl-CoA


substrate_name: NADH


substrate_name: NAD(+)


organism: Ketogulonicigenium vulgare


substrate_name: 2-keto-L-gluconic acid


substrate_name: androsterone (tested with isoform 1 in the reductive reaction)


substrate_name: delta-4-androstenedione (tested with isoform 1 in the reductive reaction)


substrate_name: estrone (tested with isoform 1 in the reductive reaction)


substrate_name: acetoacetyl-CoA (tested with isoform 1 in the reductive reaction)


substrate_name: testosterone (tested with isoform 1 in the oxidative reaction)


substrate_name: 17-beta-estradiol (tested with isoform 1 in the oxidative reaction)


organism: Oryctolagus cuniculus


substrate_name: Dihydrocodeine


substrate_name: normorphine


substrate_name: ethylmorphine


substrate_name: benzenedihydrodiol


organism: Gluconobacter oxydans


organism: Candida orthopsilosis


organism: Mesocricetus auratus


substrate_name: testosterone


substrate_name: morphine


enzyme_display_name: 2-ketogluconate reductase

organism: Gluconobacter oxydans (strain 621H)


substrate_name: NADPH


substrate_name: NADP+


organism: Pseudomonas putida

substrate_name: codeine


substrate_name: codeinone


enzyme_display_name: Glyoxylate/hydroxypyruvate reductase B

organism: Escherichia coli (strain K12)

substrate_name: hydroxypyruvate (at pH 7.5)


substrate_name: glyoxylate (at pH 7.5)


organism: Sporobolomyces salmonicolor


enzyme_display_name: Aldo-keto reductase family 1 member C15

organism: Rattus norvegicus


substrate_name: benzaldehyde


substrate_name: NADP(+)


substrate_name: NAD(+)


substrate_name: NADH


substrate_name: 4-methylpentanal (isocaproaldehyde)


substrate_name: all-trans-retinal


substrate_name: 4-hydroxy-2-nonenal (HNE)


substrate_name: 5-hydroxy-1,4-naphthoquinone (juglone)


substrate_name: 1H-indole-2,3-dione (isatin)


substrate_name: butane-2,3-dione (diacetyl)


substrate_name: methylglyoxal


substrate_name: farnesol


substrate_name: farnesal


substrate_name: geranylgeraniol


substrate_name: Benzene dihydrodiol


substrate_name: Camphorquinone


substrate_name: Dimethylglyoxal


substrate_name: m-Nitrobenzaldehyde


substrate_name: menadione


substrate_name: NAD+


substrate_name: NADH


substrate_name: p-Nitrobenzaldehyde


enzyme_display_name: Farnesol dehydrogenase

organism: Aedes aegypti

substrate_name: (E,E) farnesol


substrate_name: geraniol (E)


substrate_name: citronellol


substrate_name: octanol


enzyme_display_name: Bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase

organism: Malus domestica

substrate_name: eriodictyol


substrate_name: dihydrokaempferol


substrate_name: dihydroquercetin


substrate_name: testosterone


substrate_name: codeine


organism: Pyrus communis


substrate_name: geranylgeranial


enzyme_display_name: flavanone 4-reductase

organism: Sinningia cardinalis


organism: Homo sapiens

substrate_name: Prostaglandin E2; NAD+


substrate_name: NAD+; Prostaglandin E2


organism: Mus musculus


enzyme_display_name: Geraniol dehydrogenase

organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen)

substrate_name: Unknown


substrate_name: 3beta-Hydroxyandrost-5-en-17-one; NAD+


substrate_name: NAD+; Pregnenolone


enzyme_display_name: steroid Delta-isomerase

organism: Sus scrofa

substrate_name: NAD+; 7alpha-Hydroxycholesterol


organism: Mycobacterium tuberculosis


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2


enzyme_display_name: 11beta-hydroxysteroid dehydrogenase

substrate_name: NAD+; Cortisol


organism: Cavia porcellus

substrate_name: H+; Cortisone; NADPH


substrate_name: 7alpha-Hydroxycholesterol; NADP+


substrate_name: NADP+; Corticosterone


enzyme_display_name: 11-beta-hydroxysteroid dehydrogenase 1


organism: Saimiri sciureus


enzyme_display_name: 20alpha-hydroxysteroid dehydrogenase

organism: Tetrahymena pyriformis

substrate_name: 17alpha-Hydroxyprogesterone; NADPH; H+


substrate_name: Progesterone; H+; NADPH


substrate_name: NADPH; H+; Progesterone


organism: Oryctolagus cuniculus


enzyme_display_name: sepiapterin reductase

substrate_name: NADPH; Sepiapterin; H+


substrate_name: H+; Sepiapterin; NADPH


substrate_name: Sepiapterin; NADPH; H+


enzyme_display_name: Sepiapterin reductase

organism: Dictyostelium discoideum


enzyme_display_name: glycerol 2-dehydrogenase (NADP+)

organism: Trichoderma reesei

substrate_name: L-Glyceraldehyde; NADPH; H+


enzyme_display_name: Glycerol 2-dehydrogenase (NADP(+))

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


enzyme_display_name: 3-hydroxybutyryl-CoA dehydrogenase

organism: Clostridium acetobutylicum


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


enzyme_display_name: 7alpha-hydroxysteroid dehydrogenase

organism: Bacteroides fragilis


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: 5-alpha-pregnan-20-beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: erythrulose reductase

organism: Gallus gallus

substrate_name: NADPH; D-Erythrulose; H+


enzyme_display_name: 2-dehydropantoate 2-reductase

organism: Escherichia coli

substrate_name: 2-Dehydropantoate; H+; NADPH


organism: Thermococcus kodakarensis

substrate_name: D-pantoate


enzyme_display_name: UniProt A0A0J9X283

organism: Staphylococcus aureus


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: Unknown


organism: Rattus norvegicus

substrate_name: O2; H+; NADH; 4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol


organism: Homo sapiens

substrate_name: NSDHL; NADH


organism: Saccharomyces cerevisiae


enzyme_display_name: D-xylose 1-dehydrogenase

organism: Arthrobacter nicotinovorans

substrate_name: NAD+; D-Xylose


organism: Caulobacter vibrioides

substrate_name: D-Xylose; NAD+


enzyme_display_name: 12alpha-hydroxysteroid dehydrogenase

organism: Clostridium sp. (strain ATCC 29733 / VPI C48-50)


enzyme_display_name: D-xylose 1-dehydrogenase (NADP+)

organism: Sus scrofa

substrate_name: D-Xylose; NADP+


organism: Macaca fuscata

substrate_name: NADP+; D-Xylose


organism: Canis familiaris


organism: Oryctolagus cuniculus


organism: Trichoderma reesei


organism: Halobacterium volcanii


enzyme_display_name: geraniol dehydrogenase

organism: Ocimum basilicum

substrate_name: NADP+; Geraniol


enzyme_display_name: carbonyl reductase (NADPH)

substrate_name: 4-Nitroacetophenone; NADPH


substrate_name: Menadione; NADPH; H+


organism: Candida magnoliae

substrate_name: H+; Ethyl 4-chloro-3-oxobutanoate; NADPH


substrate_name: NADPH; H+; Menadione


organism: Mus musculus

substrate_name: H+; Pyridine-3-aldehyde; NADPH


substrate_name: NADPH; 9,10-Phenanthroquinone; H+


substrate_name: NADPH; S-Nitrosoglutathione; H+


organism: Caenorhabditis elegans

substrate_name: NADPH; H+; Isatin


organism: Mesocricetus auratus

substrate_name: Acetone; H+; NADH


enzyme_display_name: UniProt Q28960


enzyme_display_name: Dehydrogenase/reductase SDR family member 4

substrate_name: 5beta-Androstan-17b-ol-3-one (at pH7.4)


substrate_name: Unknown


substrate_name: R-(+)-1-Phenyl-1-butanol (at pH7.4)


enzyme_display_name: prostaglandin-F synthase

organism: Bos taurus

substrate_name: H+; NADPH; 9,10-Phenanthroquinone


organism: Homo sapiens


substrate_name: 9,10-Phenanthroquinone; NADPH; H+


substrate_name: Prostaglandin H2; H+; NADPH


substrate_name: NADPH; H+; Prostaglandin H2


organism: Trypanosoma brucei


substrate_name: prostaglandin PGH2


substrate_name: prostaglandin PGD2


enzyme_display_name: prostaglandin-E2 9-reductase


enzyme_display_name: Carbonyl reductase [NADPH] 1

substrate_name: 9,1 O-phenanthrene-quinone


organism: Escherichia coli


enzyme_display_name: Riboflavin biosynthesis protein PYRR, chloroplastic

organism: Zea mays


enzyme_display_name: cinnamyl-alcohol dehydrogenase

organism: Oryza sativa

substrate_name: H+; NADPH; Coniferaldehyde


organism: Populus tremuloides

substrate_name: Sinapoyl aldehyde; H+; NADPH


substrate_name: NADP+; Geraniol


organism: Arabidopsis thaliana

substrate_name: H+; NADPH; 4-Hydroxycinnamyl aldehyde


substrate_name: NADPH; 4-Hydroxycinnamyl aldehyde; H+


substrate_name: H+; Sinapoyl aldehyde; NADPH


substrate_name: NADPH; H+; Sinapoyl aldehyde


substrate_name: NADPH; H+; Coniferaldehyde


organism: Oryza sativa Japonica Group

substrate_name: 4-coumaryl aldehyde


organism: Sorghum bicolor


enzyme_display_name: UniProt C5XC49


enzyme_display_name: Cinnamyl alcohol dehydrogenase 1

organism: Medicago truncatula

substrate_name: Unknown


enzyme_display_name: aldose-6-phosphate reductase (NADPH)

organism: Malus domestica


organism: Prunus persica


organism: Clostridium sardiniense


organism: Collinsella aerofaciens


enzyme_display_name: 11-beta-hydroxysteroid dehydrogenase 1


organism: Mus musculus


organism: Rattus norvegicus


organism: Mesocricetus auratus


organism: Saimiri sciureus


enzyme_display_name: 7beta-hydroxysteroid dehydrogenase

organism: Mediterraneibacter gnavus


enzyme_display_name: 1,3-propanediol dehydrogenase

organism: Clostridium butyricum

substrate_name: NAD+; 1,3-Propanediol


enzyme_display_name: Uronate dehydrogenase

organism: Agrobacterium fabrum (strain C58 / ATCC 33970)


enzyme_display_name: IMP dehydrogenase

organism: Homo sapiens

substrate_name: H2O; NAD+; IMP


organism: Streptococcus pyogenes

substrate_name: IMP; NAD+; H2O


organism: Saccharomyces cerevisiae

substrate_name: NAD+; IMP; H2O


substrate_name: H2O; IMP; NAD+


organism: Tritrichomonas foetus


organism: Leishmania donovani


organism: Toxoplasma gondii


organism: Cryptosporidium parvum


organism: Candida albicans


organism: Borrelia burgdorferi

substrate_name: IMP; H2O; NAD+


organism: Escherichia coli


organism: Pneumocystis carinii


organism: Vigna unguiculata


organism: Eremothecium gossypii


organism: Babesia gibsoni


organism: Tritrichomonas suis


enzyme_display_name: tropinone reductase I

organism: Cochlearia officinalis

substrate_name: H+; NADPH; Tropinone


organism: Datura stramonium

substrate_name: NADPH; Tropinone


organism: Mus musculus

substrate_name: NADP+; Pregnanediol

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


enzyme_display_name: Aldo-keto reductase family 1 member C2

organism: Homo sapiens


enzyme_display_name: Aldo-keto reductase family 1 member C1


enzyme_display_name: Retinol dehydrogenase 16

substrate_name: CRBP-all-trans-retinol


enzyme_display_name: Aldo-keto reductase family 1 member C4


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: NADH tested with dihydrotestosterone


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6


organism: Rattus norvegicus


enzyme_display_name: Retinol dehydrogenase 5

organism: Bos taurus


organism: Macaca fuscata fuscata


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

substrate_name: dehydroepiandrosterone (in the presence of NAD(+))


enzyme_display_name: Aldo-keto reductase family 1 member C3


enzyme_display_name: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7


substrate_name: NADH; 3-Oxopalmitoyl-CoA; H+


substrate_name: Acenaphthen-1-ol; NADP+


enzyme_display_name: gluconate 2-dehydrogenase

substrate_name: 2-Dehydro-D-gluconate; H+; NADPH


organism: Gluconobacter oxydans


enzyme_display_name: Aldo-keto reductase family 1 member B15

substrate_name: 3-alpha,17-beta-androstandiol (tested with isoform 1 in the oxidative reaction)


enzyme_display_name: Aldo-keto reductase family 1 member C15


enzyme_display_name: morphine 6-dehydrogenase

organism: Oryctolagus cuniculus

substrate_name: trans-naphthalene dihydrodiol


enzyme_display_name: dihydroflavonol 4-reductase

organism: Delphinium cardinale

substrate_name: dihydromyricetin


substrate_name: dihydroquercetin


substrate_name: dihydrokaempferol


enzyme_display_name: Bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase

organism: Pyrus communis

substrate_name: Unknown


organism: Malus domestica


substrate_name: Phenanthrene quinone


substrate_name: NADP+


substrate_name: menadione


organism: [Clostridium] innocuum


substrate_name: 3-Ketoglycyrrhetic acid


substrate_name: NADPH


organism: Torulaspora delbrueckii

substrate_name: Diethyl 2-methyl-3-oxosuccinate


substrate_name: Diethyl 2-methyl-3-hydroxysuccinate


substrate_name: prostaglandin I2


enzyme_display_name: 8-oxocoformycin reductase

organism: Streptomyces antibioticus


enzyme_display_name: tropinone reductase II

organism: Hyoscyamus niger

substrate_name: NADH


enzyme_display_name: hydroxyphenylpyruvate reductase

organism: Arabidopsis thaliana

substrate_name: phenylpyruvate


organism: Wickerhamia fluorescens

substrate_name: Hydroxypyruvate


substrate_name: glyoxylate


substrate_name: hydroxyphenylpyruvate


organism: Coleus scutellarioides


organism: Alcaligenes sp.


substrate_name: testosterone


substrate_name: NAD+


organism: Ilyonectria destructans


substrate_name: androstendione


organism: Streptomyces exfoliatus


enzyme_display_name: 12beta-hydroxysteroid dehydrogenase

organism: Clostridium paraputrificum


organism: Solanum tuberosum

substrate_name: Nortropinone


substrate_name: tropinone


enzyme_display_name: N-acetylhexosamine 1-dehydrogenase

organism: Pseudomonas sp.

substrate_name: N-acetyl-D-glucosamine


organism: Przewalskia tangutica


organism: Brugmansia x candida


organism: Datura stramonium


enzyme_display_name: carveol dehydrogenase

organism: Rhodococcus erythropolis


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Homo sapiens

substrate_name: NAD


substrate_name: NADP


substrate_name: all-trans-retinol


substrate_name: allopregnanolone


substrate_name: androsterone


substrate_name: dehydroepiandrosterone


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 7.0 and 25 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: isoursodeoxycholic acid (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: dehydrocorticosterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of beta-hydroxybutyryl-CoA, at pH 9.3 and 25 degrees Celsius)


organism: Rattus norvegicus


substrate_name: dihydrotestosterone


substrate_name: testosterone


substrate_name: estradiol


substrate_name: testosterone (oxidation)


substrate_name: prostaglandin E1


substrate_name: prostaglandin A1


substrate_name: prostaglandin A2


substrate_name: NAD in the presence of prostaglandin E1


organism: Mentha piperita

substrate_name: (-)-trans-carveol (at pH 7.5)


substrate_name: (-)-trans-isopiperitenol (at pH 7.5)


enzyme_display_name: N-acylmannosamine 1-dehydrogenase

organism: Flavobacterium sp.

substrate_name: NAD+


substrate_name: N-acetyl-D-mannosamine


enzyme_display_name: Aldo-keto reductase family 1 member C3


substrate_name: progesterone


substrate_name: androstanediol


substrate_name: tetramyristoyl cardiolipin


substrate_name: tetralinoleoyl cardiolipin


substrate_name: prostaglandin H2


substrate_name: prostaglandin E2


organism: Mesocricetus auratus

substrate_name: NADH


substrate_name: NADP+


substrate_name: nerol


substrate_name: trans-benzene dihydrodiol


substrate_name: beta-ionol


substrate_name: cis-benzene dihydrodiol


substrate_name: farnesol


substrate_name: geraniol


substrate_name: geranylgeraniol


substrate_name: NAD+


organism: Hyoscyamus niger

substrate_name: NADPH


substrate_name: tropinone


enzyme_display_name: Tropinone reductase

organism: Cochlearia officinalis


substrate_name: nortropinone


substrate_name: quinuclidinone


organism: Wickerhamia fluorescens

substrate_name: glyoxylate


substrate_name: hydroxyphenylpyruvate


substrate_name: Hydroxypyruvate


substrate_name: NADH


substrate_name: phenylpyruvate


organism: Bos taurus

substrate_name: prostaglandin D2


substrate_name: menadione


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 2

substrate_name: estradiol


substrate_name: testosterone


substrate_name: dihydrotestosterone


substrate_name: androstenedione


substrate_name: estrone


enzyme_display_name: (3R)-3-hydroxyacyl-CoA dehydrogenase

organism: Mus musculus


substrate_name: androsterone


substrate_name: all-trans-retinol


organism: Atropa belladonna

substrate_name: NADPH


substrate_name: tropinone


organism: Malus domestica

substrate_name: eriodictyol


substrate_name: dihydrokaempferol


substrate_name: dihydroquercetin


substrate_name: NAD+


organism: Pyrus communis


substrate_name: NAD


substrate_name: NADP


substrate_name: N-glycolyl-D-mannosamine


organism: Przewalskia tangutica


substrate_name: Tropinone; H+; NADPH


substrate_name: Unknown


substrate_name: 5-alpha-pregnan-20-beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: cyclohexanol dehydrogenase

organism: Pseudomonas sp.


substrate_name: Cyclohexanol


organism: Nocardia sp.


enzyme_display_name: methanol dehydrogenase

organism: Lysinibacillus xylanilyticus

substrate_name: n-Propanol


enzyme_display_name: tetrahydroxynaphthalene reductase

organism: Pyricularia oryzae


substrate_name: Scytalone


organism: Bacillus methanolicus

substrate_name: formaldehyde


enzyme_display_name: salutaridine reductase (NADPH)

organism: Papaver somniferum

substrate_name: salutaridine


substrate_name: NADPH


substrate_name: methanol


substrate_name: ethanol


substrate_name: butanol


organism: Pyricularia grisea


substrate_name: Phenanthrenequinone


substrate_name: NADP+


substrate_name: NAD+


enzyme_display_name: D-arabinitol 2-dehydrogenase

organism: Thermotoga maritima

substrate_name: D-arabitol


substrate_name: D-ribulose


substrate_name: NADH


enzyme_display_name: (S)-carnitine 3-dehydrogenase

organism: Agrobacterium sp.


substrate_name: (S)-carnitine


organism: Xanthobacter sp.


organism: Agrobacterium sp. 525a


substrate_name: D-carnitine


substrate_name: NAD+; Ethanol


enzyme_display_name: codeinone reductase (NADPH)

substrate_name: codeine


substrate_name: codeinone


enzyme_display_name: NADPH-dependent codeinone reductase 1-3

substrate_name: codeine (at pH 9.0 and 30 degrees Celsius)


substrate_name: codeinone (at pH 9.0 and 30 degrees Celsius)


substrate_name: NADPH (at pH 9.0 and 30 degrees Celsius)


substrate_name: NADP (at pH 9.0 and 30 degrees Celsius)


substrate_name: morphine (at pH 9.0 and 30 degrees Celsius)


substrate_name: dihydrocodeine (at pH 9.0 and 30 degrees Celsius)


substrate_name: morphinone (at pH 9.0 and 30 degrees Celsius)


substrate_name: hydrocodone (at pH 9.0 and 30 degrees Celsius)


substrate_name: hydromorphone (at pH 9.0 and 30 degrees Celsius)


organism: Rhodococcus sp. (in: high G+C Gram-positive bacteria)

substrate_name: Cyclohexanol


substrate_name: Cyclopentanol


organism: Papaver bracteatum

substrate_name: NADPH


substrate_name: salutaridine


substrate_name: NADH


substrate_name: NADP+


enzyme_display_name: Salutaridine reductase

substrate_name: NADP(+)


organism: Cupriavidus necator

substrate_name: methanol


substrate_name: n-butanol


enzyme_display_name: NADPH-dependent codeinone reductase 1-5

substrate_name: codeinone


substrate_name: codeine


substrate_name: formaldehyde


substrate_name: NAD+


enzyme_display_name: NADPH-dependent codeinone reductase 1-1

substrate_name: NADPH (at pH 9.0 and 30 degrees Celsius)


substrate_name: NADP (at pH 9.0 and 30 degrees Celsius)


enzyme_display_name: NADPH-dependent codeinone reductase 1-2

substrate_name: codeine (at pH 9.0 and 30 degrees Celsius)


substrate_name: codeinone (at pH 9.0 and 30 degrees Celsius)


enzyme_display_name: NADPH-dependent codeinone reductase 1-4


organism: Candida tropicalis


substrate_name: D-arabinitol


enzyme_display_name: NAD-dependent methanol dehydrogenase


substrate_name: D-xylitol


substrate_name: D-Ribulose


substrate_name: D-Arabitol


substrate_name: NAD


enzyme_display_name: NADH-dependent L-xylulose reductase

organism: Ambrosiozyma monospora

substrate_name: L-xylulose


substrate_name: formaldehyde (without activator protein at pH 9.5 and 50 degrees Celsius)


substrate_name: ethanol (with the activator protein at pH 9.5 and 50 degrees Celsius)


substrate_name: methanol (with the activator protein at pH 9.5 and 50 degrees Celsius)


substrate_name: salutaridinol


organism: Curvularia lunata


organism: Escherichia coli (strain K12)

substrate_name: 4-(phosphooxy)-L-threonine (at 0.1 M Tris-HCl and pH 7.5)


enzyme_display_name: UniProt P9WNS1

organism: Mycobacterium tuberculosis

substrate_name: 1-deoxy-D-xylulose 5-phosphate


enzyme_display_name: UniProt P45568

organism: Escherichia coli


substrate_name: NADPH


substrate_name: Methanol; NAD+


substrate_name: Unknown


substrate_name: DNA with apurinic site


substrate_name: salutaridine (Termination and extraction with NaHCO(3) and ethylacetate, respectively)


enzyme_display_name: L-idonate 5-dehydrogenase

organism: Gluconobacter oxydans


substrate_name: NADP+


substrate_name: D-gluconate


organism: Fusarium sp.


organism: synthetic construct


organism: Aspergillus niger

substrate_name: L-Idonate


enzyme_display_name: 1,5-anhydro-D-fructose reductase

organism: Ensifer adhaerens


substrate_name: NADH


substrate_name: D-glucosone


enzyme_display_name: 3-methylbutanal reductase

organism: Saccharomyces cerevisiae


enzyme_display_name: sn-glycerol-1-phosphate dehydrogenase

organism: Pyrobaculum calidifontis


substrate_name: dihydroxyacetone phosphate


organism: Synechocystis sp.


enzyme_display_name: dTDP-4-dehydro-6-deoxyglucose reductase

organism: Aggregatibacter actinomycetemcomitans


organism: Vitis vinifera


enzyme_display_name: NADPH-dependent methylglyoxal reductase GRE2

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


organism: Methanocaldococcus jannaschii


organism: Plectranthus barbatus


substrate_name: methylglyoxal


substrate_name: phenylglyoxal


organism: Mus musculus


substrate_name: Hexanol


substrate_name: acetaldehyde


substrate_name: Butanal


substrate_name: hexanal


substrate_name: propanal


substrate_name: pentanal


substrate_name: Heptanal


organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)

substrate_name: DHAP (in the presence of NADH as coenzyme)


substrate_name: NADPH


substrate_name: G1P (in the presence of NAD as coenzyme)


substrate_name: NAD(+)


substrate_name: NADP(+)


organism: Aeropyrum pernix

substrate_name: glycerone phosphate


substrate_name: NADH


enzyme_display_name: UniProt Q2VEQ7

organism: Haloferax mediterranei


substrate_name: pyruvate


substrate_name: dihydroxyacetone phosphate


substrate_name: glycolaldehyde


substrate_name: furfural


substrate_name: acetaldehyde


substrate_name: NAD+


substrate_name: sn-Glycerol 1-phosphate


enzyme_display_name: vellosimine dehydrogenase

organism: Rauvolfia serpentina

substrate_name: vellosimine


substrate_name: geissoschizal


enzyme_display_name: 3beta-hydroxysteroid 3-dehydrogenase

organism: Eggerthella sp. CAG:298

substrate_name: 3-oxodeoxycholic acid


substrate_name: isodeoxycholic acid


enzyme_display_name: D-2-hydroxyacid dehydrogenase (NADP+)

substrate_name: NADPH


organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: DHAP (in the presence of NADH as coenzyme)


substrate_name: NAD(+)


enzyme_display_name: (R)-2-hydroxyacid dehydrogenase

organism: Enterococcus faecalis

substrate_name: H+; NADH; 2-Oxobutyrate


organism: Zea mays

mutation_signature: Δ7


substrate_name: cycloartenone


substrate_name: cyclolaudenone


substrate_name: cycloeucalenone


substrate_name: cholestanone


organism: Escherichia coli

substrate_name: 1-Deoxy-D-xylulose 5-phosphate


enzyme_display_name: 4-methyl-2-oxopentanoate reductase A

organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40)

substrate_name: 4-methyl-2-oxopentanoate (MOA)


substrate_name: pyruvate


substrate_name: hydroxypyruvate


substrate_name: glyoxylate


substrate_name: phenylpyruvate


substrate_name: NADH


enzyme_display_name: 2-hydroxyacid dehydrogenase A


organism: Corynebacterium sp.


enzyme_display_name: 2-(R)-hydroxypropyl-CoM dehydrogenase

organism: Xanthobacter autotrophicus


organism: Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)


substrate_name: NADH (at pH 7.5)


enzyme_display_name: NADPH-dependent 3-keto-steroid reductase Hsd3b5

organism: Rattus norvegicus

substrate_name: dihydrotestosterone (in the presence of NADPH)


enzyme_display_name: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1


enzyme_display_name: D-specific alpha-keto acid dehydrogenase

organism: Enterococcus faecium

substrate_name: pyruvate (in the presence of NADPH at pH 5.6)


substrate_name: alpha-ketobutyrate (in the presence of NADPH at pH 5.6)


substrate_name: alpha-ketovalerate (in the presence of NADPH at pH 5.6)


substrate_name: alpha-ketocaproate (in the presence of NADPH at pH 5.6)


substrate_name: alpha-ketoisocaproate (in the presence of NADPH at pH 5.6)


substrate_name: NADPH (at pH 5.6)


substrate_name: NADH (at pH 5.6)


enzyme_display_name: Aldo-keto reductase family 1 member C1

organism: Homo sapiens

substrate_name: (s)-tetralol


enzyme_display_name: 2-(S)-hydroxypropyl-CoM dehydrogenase 3


substrate_name: NAD(+)


organism: Oryctolagus cuniculus


substrate_name: methylglyoxal


substrate_name: progesterone (reduction)


substrate_name: testosterone (oxidation)


enzyme_display_name: 2-(S)-hydroxypropyl-CoM dehydrogenase


substrate_name: NADPH


organism: Xanthobacter sp.


enzyme_display_name: Dehydrogenase/reductase SDR family member 11

substrate_name: 5-beta-androstane-3,17-dione (at 37 degrees Celsius)


substrate_name: 4-androstene-3,17-dione (at 37 degrees Celsius)


substrate_name: progesterone (at 37 degrees Celsius)


substrate_name: 5-beta-pregnane-3,20-dione (at 37 degrees Celsius)


substrate_name: 17-beta-estradiol (at 37 degrees Celsius)


substrate_name: testosterone (at 37 degrees Celsius)


substrate_name: 5-alpha-androstane-3-alpha,17-beta-diol (at 37 degrees Celsius)


substrate_name: isolithocholic acid (at 37 degrees Celsius)


substrate_name: 1-phenyl-1,2-propanedione (at 37 degrees Celsius)


substrate_name: 2,3-hexanedione (at 37 degrees Celsius)


substrate_name: 2,3-heptanedione (at 37 degrees Celsius)


substrate_name: 3,4-hexanedione (at 37 degrees Celsius)


substrate_name: alpha-tetralone (at 37 degrees Celsius)


substrate_name: loxoprofen (at 37 degrees Celsius)


substrate_name: dehydroepiandrosterone


substrate_name: NAD+


substrate_name: NADPH


substrate_name: estrone (at 37 degrees Celsius)


substrate_name: 5-alpha-androstan-3-alpha-ol-17-one (at 37 degrees Celsius)


substrate_name: dehydroepiandrosterone (DHEA) (at 37 degrees Celsius)


substrate_name: DHEA sulfate (at 37 degrees Celsius)


substrate_name: dehydrolithocholic acid (at 37 degrees Celsius)


substrate_name: 20-alpha-hydroxyprogesterone (at 37 degrees Celsius)


substrate_name: taurodehydrocholic acid (at 37 degrees Celsius)


substrate_name: dehydrocholic acid (at 37 degrees Celsius)


substrate_name: 5-beta-dihydrotestosterone (DHT) (at 37 degrees Celsius)


organism: Yersinia pestis


substrate_name: 1-deoxy-D-xylulose 5-phosphate


substrate_name: glycerol


substrate_name: dihydroxyacetone


enzyme_display_name: GDP-L-fucose synthase

organism: Escherichia coli (strain K12)


substrate_name: NADH


organism: Bacillus subtilis (strain 168)

substrate_name: DHAP


substrate_name: NAD(+)


enzyme_display_name: 1,5-anhydro-D-fructose reductase

substrate_name: NADPH (at 25 degrees Celsius)


substrate_name: NADH (at 25 degrees Celsius)


enzyme_display_name: sn-glycerol-1-phosphate dehydrogenase

organism: Bacillus subtilis

substrate_name: NAD+


substrate_name: sn-Glycerol 1-phosphate


substrate_name: glycerone phosphate


substrate_name: 9,10-phenanthrenequinone with NADPH as cofactor


organism: Thermotoga maritima

substrate_name: NADPH


organism: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)


organism: Sus scrofa


enzyme_display_name: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

organism: Mus musculus

substrate_name: estrone


organism: Escherichia coli


substrate_name: 1,2-Dideoxy-D-hexulose 6-phosphate


organism: Mycobacterium tuberculosis


substrate_name: dihydrotestosterone


enzyme_display_name: NADPH-dependent 3-keto-steroid reductase Hsd3b4


substrate_name: 1-Fluoro-1-deoxy-D-xylulose 5-phosphate


organism: Taiwanofungus camphoratus

substrate_name: S-nitrosoglutathione


substrate_name: S-(hydroxymethyl)glutathione


enzyme_display_name: UniProt P11766


enzyme_display_name: UniProt Q5JFV8

organism: Thermococcus kodakarensis

substrate_name: homoisocitrate


substrate_name: isocitrate


enzyme_display_name: UniProt Q72IW9

organism: Thermus thermophilus


substrate_name: dihydrotestosterone (in the presence of NADH)


enzyme_display_name: xanthoxin dehydrogenase

organism: Arabidopsis thaliana

substrate_name: xanthoxin


enzyme_display_name: sorbose reductase

organism: Candida albicans

substrate_name: D-fructose


enzyme_display_name: 2-(R)-hydroxypropyl-CoM dehydrogenase


enzyme_display_name: momilactone-A synthase

organism: Oryza sativa

substrate_name: oryzalexin A


organism: Gluconobacter oxydans


substrate_name: D-mannitol


substrate_name: L-sorbose


organism: Ensifer adhaerens


organism: Eubacterium barkeri


organism: Bacillus cereus


substrate_name: NADP+


substrate_name: NAD+


organism: Unknown

substrate_name: Unknown

source_db: unknown

source_license: see source


enzyme_display_name: diacetyl reductase [(R)-acetoin forming]

organism: Shouchella clausii

substrate_name: diacetyl


organism: Metallosphaera sedula

substrate_name: malonate semialdehyde


substrate_name: NADPH


enzyme_display_name: NADP-retinol dehydrogenase


substrate_name: retinal


enzyme_display_name: Aldo-keto reductase family 1 member B15

organism: Homo sapiens

substrate_name: all-trans-retinal


substrate_name: D,L-glyceraldehyde


substrate_name: hexanal


substrate_name: acrolein


substrate_name: farnesal


enzyme_display_name: Retinol dehydrogenase 12


substrate_name: NADH


substrate_name: nonanal


enzyme_display_name: Dehydrogenase/reductase SDR family member 4

organism: Oryctolagus cuniculus

substrate_name: 16-Ketoestrone (at pH6)


substrate_name: all-trans-Retinal (at pH7.4)


substrate_name: Isatin (at pH6)


substrate_name: Propiophenone (at pH6)


substrate_name: Heptanophenone (at pH6)


substrate_name: Nonanophenone (at pH6)


substrate_name: 4-Hexanoylpyridine (at pH6)


substrate_name: Hexanophenone (at pH6)


substrate_name: Valerophenone (at pH6)


substrate_name: n-Butyrophenone (at pH6)


substrate_name: 3-Benzoylpyridine (at pH6)


substrate_name: 4-Benzoylpyridine (at pH6)


substrate_name: 2,3-Hexanedione (at pH6)


substrate_name: 1-phenyl-1,2-propanedione (at pH6)


substrate_name: Benzil (at pH6)


substrate_name: Diacetyl (at pH6)


substrate_name: Pyridine-4-aldehyde (at pH6)


substrate_name: 1-Phenylisatin (at pH6)


substrate_name: 9,10-Phenanthrenequinone (at pH6)


substrate_name: Menadione (at pH6)


substrate_name: S-(-)-1-Phenyl-1-butanol (at pH7.4)


substrate_name: all-trans-Retinol (at pH7.4)


enzyme_display_name: NADP-dependent 3-hydroxy acid dehydrogenase YdfG

organism: Escherichia coli (strain K12)

substrate_name: NADP(+) (at pH 9 and at 30 degrees Celsius)


substrate_name: L-serine (at pH 9 and at 30 degrees Celsius)


substrate_name: D-threonine (at pH 9 and at 30 degrees Celsius)


substrate_name: L-glycerate (at pH 9 and at 30 degrees Celsius)


substrate_name: D-glycerate (at pH 9 and at 30 degrees Celsius)


substrate_name: androsterone (tested with isoform 1 in the reductive reaction)


substrate_name: delta-4-androstenedione (tested with isoform 1 in the reductive reaction)


substrate_name: estrone (tested with isoform 1 in the reductive reaction)


substrate_name: acetoacetyl-CoA (tested with isoform 1 in the reductive reaction)


substrate_name: testosterone (tested with isoform 1 in the oxidative reaction)


substrate_name: 17-beta-estradiol (tested with isoform 1 in the oxidative reaction)


organism: Sus scrofa

substrate_name: 16-Ketoestrone (at pH6)


substrate_name: all-trans-Retinal (at pH7.4)


substrate_name: isatin (at pH6)


substrate_name: Propiophenone (at pH6)


substrate_name: Heptanophenone (at pH6)


substrate_name: Nonanophenone (at pH6)


substrate_name: 4-Hexanoylpyridine (at pH6)


substrate_name: Hexanophenone (at pH6)


substrate_name: Valerophenone (at pH6)


substrate_name: n-Butyrophenone (at pH6)


substrate_name: 3-Benzoylpyridine (at pH6)


substrate_name: 4-Benzoylpyridine (at pH6)


substrate_name: 2,3-Hexanedione (at pH6)


substrate_name: 1-phenyl-1,2-propanedione (at pH6)


substrate_name: Benzil (at pH6)


substrate_name: Diacetyl (at pH6)


substrate_name: Pyridine-4-aldehyde (at pH6)


substrate_name: 1-Phenylisatin (at pH6)


substrate_name: 9,10-Phenanthrenequinone (at pH6)


substrate_name: Menadione (at pH6)


substrate_name: S-(-)-1-Phenyl-1-butanol (at pH7.4)


substrate_name: all-trans-Retinol (at pH7.4)


enzyme_display_name: Retinol dehydrogenase 14

substrate_name: NADPH


substrate_name: NADP


substrate_name: all-trans-retinal


substrate_name: all-trans-retinol


substrate_name: NADH


enzyme_display_name: D-arabitol-phosphate dehydrogenase

organism: Enterococcus avium


substrate_name: NAD+


substrate_name: NADP+


substrate_name: D-arabitol 1-phosphate


enzyme_display_name: diacetyl reductase [(S)-acetoin forming]

organism: Columba livia


substrate_name: diacetyl


enzyme_display_name: malate dehydrogenase [NAD(P)+]

organism: Flavobacterium frigidimaris


substrate_name: L-malate


enzyme_display_name: Aldo-keto reductase family 1 member B1

substrate_name: acrolein


organism: Geobacillus stearothermophilus


enzyme_display_name: D-xylose reductase [NAD(P)H]

organism: Yamadazyma tenuis


organism: Thermochaetoides thermophila

substrate_name: D-glucose


substrate_name: L-arabinose


organism: Neurospora crassa

substrate_name: D-xylose


organism: Scheffersomyces stipitis


substrate_name: 5alpha-Pregnane-3,20-dione (at pH7.4)


substrate_name: Dehydrolithocholic acid (at pH7.4)


substrate_name: 2,3-Pentanedione (at pH6)


substrate_name: Methyl benzoylformate (at pH6)


substrate_name: 4-Nitrobenzaldehyde (at pH6)


enzyme_display_name: Aldo-keto reductase family 1 member B10


enzyme_display_name: UniProt D3U1D9

organism: Klebsiella oxytoca


substrate_name: isethionate


enzyme_display_name: UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)

organism: Ralstonia solanacearum

substrate_name: UDP-glucuronic acid


organism: Mus musculus

substrate_name: D,L-glyceraldehyde


substrate_name: D-glucuronate


enzyme_display_name: (S)-sulfolactate dehydrogenase

organism: Chromohalobacter israelensis

substrate_name: NADH


substrate_name: NAD+


enzyme_display_name: Retinol dehydrogenase 11

substrate_name: all-trans-retinal


substrate_name: NADPH


enzyme_display_name: Malate dehydrogenase

organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: (2S,3S)-tartrate (in the presence of NAD)


substrate_name: NAD (in the presence of malate)


substrate_name: NADP (in the presence of malate)


organism: Homo sapiens


substrate_name: glucose


enzyme_display_name: 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase

organism: Sphingomonas paucimobilis


substrate_name: NADP+


organism: Chlorobaculum tepidum

substrate_name: diacetyl


enzyme_display_name: 5-exo-hydroxycamphor dehydrogenase

organism: Pseudomonas putida


enzyme_display_name: isoeugenol synthase

organism: Daucus carota subsp. sativus

substrate_name: coniferyl acetate


enzyme_display_name: eugenol synthase

organism: Ocimum kilimandscharicum


substrate_name: 4-coumaryl acetate


organism: Phytopseudomonas straminea


substrate_name: Unknown


organism: Larrea tridentata


enzyme_display_name: UniProt Q7NQL0

organism: Chromobacterium violaceum

substrate_name: UDP-alpha-D-glucuronate


organism: Ocimum tenuiflorum


enzyme_display_name: benzil reductase [(S)-benzoin forming]

organism: Ogataea glucozyma

substrate_name: benzil


enzyme_display_name: chanoclavine-I dehydrogenase

organism: Penicillium roqueforti


substrate_name: chanoclavine-I


organism: Trichophyton benhamiae


organism: Bordetella pertussis


enzyme_display_name: (+)-thujan-3-ol dehydrogenase

organism: Tanacetum vulgare


enzyme_display_name: (-)-endo-fenchol dehydrogenase

organism: Anethum foeniculum

substrate_name: (-)-endo-fenchol


organism: Ocimum gratissimum


organism: Weissella confusa


substrate_name: phenylglyoxylate


substrate_name: pyruvate


substrate_name: phenylpyruvate


substrate_name: oxo-tert-leucine


substrate_name: NAD+


organism: Pimpinella anisum


enzyme_display_name: D-2-hydroxyacid dehydrogenase (NAD+)

organism: Lacticaseibacillus paracasei

substrate_name: NADH


enzyme_display_name: phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)

organism: Thermotoga maritima


substrate_name: L-lactate


enzyme_display_name: very-long-chain 3-oxoacyl-CoA reductase

organism: Gossypium hirsutum

substrate_name: NADPH


substrate_name: Nonanal


enzyme_display_name: L-galactose 1-dehydrogenase

organism: Lathyrus oleraceus

substrate_name: L-galactose


organism: Methanobrevibacter millerae


substrate_name: sulfopyruvate


organism: Gluconacetobacter diazotrophicus


substrate_name: NADP+


organism: Methanothermus fervidus


substrate_name: oxaloacetate


enzyme_display_name: 8-hydroxygeraniol dehydrogenase

organism: Rauvolfia serpentina

substrate_name: Nerol; NADP+


organism: Petunia x hybrida

substrate_name: coniferyl acetate


organism: Musca domestica

substrate_name: sepiapterin


enzyme_display_name: Benzil reductase ((S)-benzoin forming)

organism: Bacillus cereus

substrate_name: benzil (with NADPH at 37 degrees Celsius and pH 6.5)


substrate_name: 1-phenyl-1,2-propanedione (with NADPH at 37 degrees Celsius and pH 6.5)


substrate_name: 1,4-naphthoquinone (with NADPH at 37 degrees Celsius and pH 6.5)


substrate_name: p-nitrobenzaldehyde (with NADPH and at 37 degrees Celsius and pH 6.5)


substrate_name: methyl benzoylformate (with NADPH and at 37 degrees Celsius and pH 6.5)


enzyme_display_name: CDP-paratose synthase

organism: Salmonella enterica subsp. enterica serovar Typhi


enzyme_display_name: Retinol dehydrogenase 11

organism: Homo sapiens


substrate_name: NADP


substrate_name: all-trans-retinal


substrate_name: all-trans-retinol


enzyme_display_name: D-xylose reductase [NAD(P)H]

organism: Scheffersomyces stipitis

substrate_name: D-xylose


substrate_name: NADPH


substrate_name: NADH


organism: Methanocaldococcus jannaschii


substrate_name: 2-oxopentanedioic acid


enzyme_display_name: methylecgonone reductase

organism: Erythroxylum coca

substrate_name: NADP+


enzyme_display_name: Dehydrogenase/reductase SDR family member 4

organism: Oryctolagus cuniculus

substrate_name: 4-Acetylpyridine (at pH6)


substrate_name: Pyridine-3-aldehyde (at pH6)


substrate_name: 4-Nitroacetophenone (at pH6)


enzyme_display_name: NADP-retinol dehydrogenase

organism: Danio rerio


substrate_name: estrone


enzyme_display_name: zerumbone synthase

organism: Zingiber zerumbet

substrate_name: NAD+


enzyme_display_name: Zerumbone synthase

substrate_name: NAD


substrate_name: borneol


organism: Rasamsonia emersonii


enzyme_display_name: phosphonoacetaldehyde reductase (NADH)

organism: Streptomyces viridochromogenes

substrate_name: phosphonoacetaldehyde


substrate_name: methyl ecgonone