enzyme_display_name: UniProt P21889

substrate_name: L-Asp


enzyme_display_name: peptidylprolyl isomerase

organism: Homo sapiens

source_db: brenda

verification_status: unverified

ki_display: Not reported

kcat_over_km_display: Not reported

mutation_signature: Unknown

source_license: CC BY 4.0

km_unit: mM


enzyme_display_name: microtubule-severing ATPase

substrate_name: ATP


enzyme_display_name: guanylate cyclase

substrate_name: GTP


enzyme_display_name: cysteine-S-conjugate beta-lyase

substrate_name: S-(p-bromophenyl)-L-cysteine

kcat_display: Not reported


enzyme_display_name: glutamate--cysteine ligase

substrate_name: L-Glutamate; L-alpha-Aminobutyrate; ATP

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


enzyme_display_name: methionine--tRNA ligase

organism: Saccharomyces cerevisiae

substrate_name: tRNAMet


substrate_name: L-homocysteine


substrate_name: CoA


enzyme_display_name: bisphosphoglycerate mutase


enzyme_display_name: D-alanine--poly(phosphoribitol) ligase

organism: Lacticaseibacillus casei

substrate_name: D-Ala


substrate_name: D-2-amino-n-butyric acid


enzyme_display_name: lysine--tRNA ligase

organism: Cricetinae


substrate_name: L-lysine

mutation_signature: recombinant N-terminally truncated enzyme


substrate_name: human tRNALys3


substrate_name: yeast tRNALys


organism: Lactiplantibacillus plantarum

substrate_name: diphosphate


enzyme_display_name: valine--tRNA ligase

organism: Euglena gracilis

substrate_name: tRNAVal


substrate_name: L-valine


enzyme_display_name: aspartate--tRNA ligase

organism: Pseudomonas aeruginosa

substrate_name: tRNAAsp


substrate_name: L-aspartate


substrate_name: ATP


substrate_name: ATP; L-Aspartate; tRNA(Asp)

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: tRNA(Asp); L-Aspartate; ATP


substrate_name: L-Aspartate

source_db: oed


organism: Thermus thermophilus

substrate_name: ATP; tRNA(Asp); L-Aspartate

protein_accession_database: UniProt


organism: Tetrahymena pyriformis

substrate_name: valine


enzyme_display_name: serine--tRNA ligase

organism: Zea mays

substrate_name: tRNASer


substrate_name: L-serine


organism: Mycolicibacterium smegmatis

substrate_name: L-Met


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: E.coli tRNAfMet

source_db: uniprot


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: tRNA(Met) (in the absence of ARC1)


organism: Escherichia coli

substrate_name: tRNASecUX


substrate_name: tRNAUTuX


organism: Methanosarcina barkeri


organism: Acanthamoeba polyphaga mimivirus

substrate_name: ATP; tRNA(Met); L-Methionine


organism: Enterococcus faecalis

substrate_name: ATP; L-Methionine; tRNA(Met)


organism: Homo sapiens

substrate_name: tRNA-Met


organism: Saccharomyces cerevisiae


organism: Bacillus subtilis

substrate_name: ATP; tRNA(Lys); L-Lysine


substrate_name: ATP; Valine


organism: Methanosarcina barkeri (strain Fusaro / DSM 804)

substrate_name: tRNA(Ser CGA)


substrate_name: L-Aspartate; ATP; tRNA(Asp)


organism: Thermococcus kodakaraensis

substrate_name: ATP; L-Aspartate; tRNA(Asp)


organism: Thermococcus kodakarensis

substrate_name: tRNAAsn


organism: Cricetulus griseus

substrate_name: tRNA(Lys); ATP; L-Lysine


substrate_name: tRNA(Lys); L-Lysine; ATP


organism: Pyrococcus horikoshii

substrate_name: tRNALysGUU


enzyme_display_name: alanine--tRNA ligase

substrate_name: tRNA(Ala) (at 37 Celsius)


organism: Geobacillus stearothermophilus

substrate_name: Threonine

verification_status: corrected


kcat_over_km_origin: calculated


substrate_name: valine


verification_status: verified


organism: Escherichia coli (strain K12)

substrate_name: L-methionine


substrate_name: ATP


substrate_name: tRNAAsp


organism: Thermus thermophilus

substrate_name: tRNA(Asp); ATP; L-Aspartate


organism: Vigna radiata var. radiata

substrate_name: threo-3-hydroxyaspartic acid


substrate_name: Ser


substrate_name: L-serine


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: L-aspartate (at 37 degrees Celsius)


substrate_name: ATP (at 37 degrees Celsius)


substrate_name: L-Ser


organism: Cryptosporidium parvum


substrate_name: L-lysine


substrate_name: Valine; ATP


substrate_name: L-Valine; tRNA(Val); ATP


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: methionine


organism: Escherichia coli


organism: Methanosarcina barkeri


enzyme_display_name: serine racemase

organism: Homo sapiens

substrate_name: Unknown

km_display: Not reported

ki_unit: mM


substrate_name: L-Lysine


substrate_name: lysine


substrate_name: Met


substrate_name: ATP


substrate_name: valine


organism: Saccharomyces cerevisiae


substrate_name: L-Aspartate


organism: Acanthamoeba polyphaga mimivirus

substrate_name: L-Methionine


organism: Paracoccus denitrificans

substrate_name: L-Met


substrate_name: selenomethionine


substrate_name: norleucine


organism: Mycolicibacterium smegmatis


organism: Clostridioides difficile

substrate_name: tRNAMet


substrate_name: L-methionine


organism: Staphylococcus aureus


substrate_name: threonine


organism: Borreliella burgdorferi

substrate_name: L-lysine


substrate_name: tRNALysUUU


substrate_name: tRNAAsp


substrate_name: aspartate


substrate_name: Asp


substrate_name: 2-aminomalonic acid


substrate_name: L-serine


substrate_name: glycine


substrate_name: L-alanine


organism: Geobacillus stearothermophilus

substrate_name: ATP


organism: Xanthomonas citri


substrate_name: alanine


substrate_name: L-valine


substrate_name: tRNAVal


substrate_name: L-threonine


substrate_name: tRNAAla


substrate_name: tRNAMet


substrate_name: DL-threonine


substrate_name: (S)-2-aminohex-5-enoic acid


substrate_name: L-norleucine


substrate_name: (S)-2-aminohex-5-ynoic acid


substrate_name: L-methionine


substrate_name: tRNASer


substrate_name: L-Ser


organism: Zea mays


mutation_signature: human mutant tRNALys / N-terminally truncated mutant enzyme


substrate_name: Unknown

mutation_signature: N-terminally truncated mutant enzyme


organism: Plasmodium falciparum

substrate_name: tRNAAsp


substrate_name: L-aspartate


substrate_name: L-serine


organism: Lupinus luteus


substrate_name: Ser


substrate_name: ATP


substrate_name: dATP


mutation_signature: truncated enzyme Ser / truncated enzyme


mutation_signature: truncated enzyme aminoacylation / truncated enzyme


organism: Anabaena sp.

substrate_name: L-valine


substrate_name: tRNAVal(GAC)


substrate_name: L-isoleucine


organism: Bacillus cereus

substrate_name: L-lysine


organism: Escherichia coli

substrate_name: L-methionyl-tRNAMet


organism: Leishmania donovani


organism: Haemophilus influenzae


organism: Mycobacterium tuberculosis


organism: Lupinus sp.

substrate_name: tRNAMet


substrate_name: Met


organism: Pseudomonas aeruginosa

substrate_name: tRNALys


substrate_name: Asp


organism: Rattus norvegicus

substrate_name: tRNAVal


substrate_name: valine


organism: Saccharomyces cerevisiae


substrate_name: tRNASer


enzyme_display_name: threonine--tRNA ligase

substrate_name: Formycin 5'-triphosphate


substrate_name: 2-Chloroadenosine 5'-triphosphate


organism: Streptococcus pneumoniae

substrate_name: L-methionine


substrate_name: ATP


substrate_name: Unknown


organism: Streptomyces sp.


substrate_name: L-serine


substrate_name: aspartyl-tRNA


substrate_name: tRNAAla


substrate_name: alanine


organism: Sus scrofa

substrate_name: tRNAAsp


substrate_name: L-cysteine


substrate_name: L-threonine


substrate_name: DL-Serine hydroxamate


organism: Thermus thermophilus

mutation_signature: C-terminally truncated mutant enzyme


organism: Vigna radiata var. radiata

substrate_name: Met


substrate_name: selenomethionine


organism: Bombyx mori


organism: Bos taurus

substrate_name: L-aspartate


substrate_name: liver tRNA


substrate_name: L-Ser


substrate_name: L-lysyl-tRNALys


substrate_name: L-lysine


substrate_name: tRNAMet


mutation_signature: C-terminally truncated mutant


substrate_name: Asp


substrate_name: ATP


organism: Geobacillus stearothermophilus

substrate_name: valine


substrate_name: L-methionine


organism: Homo sapiens

substrate_name: L-alanine


substrate_name: tRNAAsp

mutation_signature: truncated enzyme truncated enzyme


organism: Methanothermobacter thermautotrophicus


substrate_name: tRNALys


organism: Plasmodium falciparum


organism: Oryza sativa

substrate_name: tRNA fraction from Saccharomyces cerevisiae

mutation_signature: truncated mutant


organism: Pyrococcus abyssi


substrate_name: Lys


organism: Escherichia coli


substrate_name: tRNASer


substrate_name: L-valyl-tRNAVal


substrate_name: L-aspartate


substrate_name: D-Ser


substrate_name: Formycin 5'-triphosphate


organism: Triticum aestivum

substrate_name: Met


substrate_name: tRNAAsn


organism: Arabidopsis thaliana

substrate_name: tRNALysCUU


substrate_name: tRNASerGCU


organism: Borreliella burgdorferi

substrate_name: tRNALysUUC


substrate_name: ATP


substrate_name: tmRNA


substrate_name: tRNAPhe(57); tRNAAla; tRNAPhe(17); tRNAPhe(38)


substrate_name: L-trans-alpha-crotylglycine


substrate_name: L-Lysine amide


substrate_name: L-norvaline


substrate_name: L-valine


enzyme_display_name: thromboxane-A synthase

substrate_name: Unknown


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


enzyme_display_name: lactoylglutathione lyase

substrate_name: Phenylglyoxal


substrate_name: tRNAMet

mutation_signature: recombinant C-terminally truncated enzyme


substrate_name: tRNAAsp


enzyme_display_name: prostaglandin-D synthase

substrate_name: prostaglandin H2


enzyme_display_name: pancreatic ribonuclease

substrate_name: cyclic 2',3'-CMP


substrate_name: L-Met


enzyme_display_name: channel-conductance-controlling ATPase


enzyme_display_name: methylmalonyl-CoA mutase


enzyme_display_name: leukotriene-C4 synthase

substrate_name: glutathione


substrate_name: tRNASec mutant without anticodon arm


organism: Hordeum vulgare


enzyme_display_name: glutamate--cysteine ligase

substrate_name: L-Glu


enzyme_display_name: dichloromethane dehalogenase

organism: Hyphomicrobium sp.

substrate_name: Dichloromethane


enzyme_display_name: L-ribulose-5-phosphate 4-epimerase

organism: Klebsiella aerogenes

substrate_name: L-ribulose 5-phosphate


enzyme_display_name: aspartate--ammonia ligase

substrate_name: Asp


enzyme_display_name: N-acylglucosamine 2-epimerase

substrate_name: N-acetyl-D-mannosamine


enzyme_display_name: protoporphyrin ferrochelatase

substrate_name: protoporphyrin


organism: Komagataeibacter xylinus

substrate_name: alpha-D-glucose 1-phosphate


enzyme_display_name: xylose isomerase

organism: Lachnoclostridium phytofermentans

substrate_name: D-xylose


enzyme_display_name: isomaltulose synthase

organism: Klebsiella sp. LX3

substrate_name: sucrose


enzyme_display_name: S-ribosylhomocysteine lyase

organism: Lactiplantibacillus plantarum

substrate_name: S-ribosylhomocysteine


organism: Klebsiella sp.


enzyme_display_name: glutamate racemase

substrate_name: L-glutamate


enzyme_display_name: galactose-6-phosphate isomerase

organism: Lactococcus lactis

substrate_name: D-altrose


enzyme_display_name: UniProt P9WFV9

organism: Mycobacterium tuberculosis

substrate_name: ATP

source_db: skid

source_license: CC BY-NC-ND 4.0


enzyme_display_name: UniProt P00962

substrate_name: L-glutamine


enzyme_display_name: UniProt O95363

organism: Homo sapiens


enzyme_display_name: aspartate--tRNA ligase


organism: Lactococcus lactis subsp. lactis


enzyme_display_name: beta-phosphoglucomutase

substrate_name: beta-D-glucose 1-phosphate


substrate_name: D-allose


substrate_name: Unknown


enzyme_display_name: cysteine--tRNA ligase


substrate_name: tRNA(Cys); ATP; L-Cysteine


substrate_name: L-Cysteine


substrate_name: L-Cysteine; ATP; tRNA(Cys)


substrate_name: ATP; L-Cysteine; tRNA(Cys)


substrate_name: tRNA(Cys); L-Cysteine; ATP


enzyme_display_name: proline--tRNA ligase

organism: Delonix regia

substrate_name: L-Pro


substrate_name: L-thiazolidine-4-carboxylic acid


substrate_name: N-methylglycine


organism: Hemerocallis fulva


substrate_name: L-azetidine-2-carboxylic acid


enzyme_display_name: phenylalanine--tRNA ligase

organism: Escherichia coli

substrate_name: tRNA(Phe); ATP; L-Phenylalanine


enzyme_display_name: histidine--tRNA ligase

substrate_name: L-Histidine


substrate_name: L-Histidine; ATP; tRNA(His)


organism: Ranunculus bulbosus


organism: Parkinsonia aculeata


substrate_name: L-Cysteine; tRNA(Cys); ATP


enzyme_display_name: glutamate--tRNA ligase

substrate_name: tRNA(Glu); L-Glutamate; ATP


organism: Saccharomyces cerevisiae


substrate_name: ATP; tRNA(Glu); L-Glutamate


organism: Bacillus subtilis

substrate_name: ATP; L-Phenylalanine; tRNA(Phe)


organism: Astragalus crotalariae


substrate_name: Cys


substrate_name: selenocysteine


substrate_name: 2-aminobutyric acid


organism: Astragalus lentiginosus

substrate_name: tRNA(Cys); ATP; L-Cysteine


organism: Convallaria majalis


organism: Astragalus racemosus


substrate_name: tRNAPhe


substrate_name: ATP


organism: Arabidopsis thaliana

substrate_name: L-proline


organism: Magnetospirillum magnetotacticum

substrate_name: ATP; L-Proline; tRNA(Pro)


organism: Methanothermobacter thermautotrophicus

substrate_name: L-Proline


substrate_name: L-Cysteine


substrate_name: tRNA(Pro); ATP; L-Proline


substrate_name: L-phenylalanine


organism: Paracoccus denitrificans


substrate_name: L-Cys


substrate_name: diphosphate


enzyme_display_name: glycine--tRNA ligase

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: glycine (at 25 degrees Celsius)


organism: Cytophaga hutchinsonii

substrate_name: L-cysteine


organism: Methanocaldococcus jannaschii


organism: Homo sapiens

substrate_name: glycine


organism: Neurospora crassa

substrate_name: His


substrate_name: L-tyrosine


organism: Escherichia coli (strain K12)


enzyme_display_name: arginine--tRNA ligase

organism: Canavalia ensiformis

substrate_name: L-canavanine


organism: Escherichia coli

source_license: CC BY 4.0; CC BY-NC-ND 4.0


substrate_name: DL-m-tyrosine


organism: Aquifex aeolicus

substrate_name: L-Proline; ATP; tRNA(Pro)


organism: Borrelia burgdorferi

substrate_name: tRNA(Pro); L-Proline; ATP


organism: Clostridium sticklandii


substrate_name: L-Proline; tRNA(Pro); ATP


organism: Beta vulgaris

substrate_name: L-Pro


organism: Staphylococcus aureus

substrate_name: ATP


substrate_name: Gly


substrate_name: L-proline


organism: Acetoanaerobium sticklandii


substrate_name: L-Cysteine


organism: Deinococcus radiodurans


organism: Paramagnetospirillum magnetotacticum


organism: Methanothermobacter thermautotrophicus


organism: Novosphingobium aromaticivorans

substrate_name: ATP; L-Proline; tRNA(Pro)


organism: Rhodopseudomonas palustris


organism: Thermus thermophilus


organism: Astragalus bisulcatus

substrate_name: ATP; L-Cysteine; tRNA(Cys)


organism: Homo sapiens

substrate_name: tRNA(Cys)


substrate_name: L-arginine


substrate_name: L-cysteine


organism: Saccharomyces cerevisiae

substrate_name: L-tryptophan


substrate_name: L-phenylalanine


organism: Oryctolagus cuniculus

substrate_name: tRNACys


organism: Bacillus subtilis

substrate_name: L-Glutamate; tRNA(Glu); ATP


organism: Escherichia coli

substrate_name: tRNA(Glu); L-Glutamate; ATP


substrate_name: tRNA(Glu)


organism: Mycobacterium tuberculosis

substrate_name: L-glutamate


organism: Thermosynechococcus elongatus

substrate_name: L-Glutamate; ATP; tRNA(Glu)


enzyme_display_name: glutamine--tRNA ligase

substrate_name: L-Glutamine; tRNA(Gln); ATP

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


substrate_name: tRNA(Arg); ATP; L-Arginine


organism: Mycolicibacterium smegmatis

substrate_name: tRNAArg


substrate_name: ATP; L-Histidine; tRNA(His)


substrate_name: Cys


substrate_name: 2-aminobutyric acid


substrate_name: ATP


substrate_name: L-histidine


substrate_name: histidine


organism: Methanocaldococcus jannaschii

substrate_name: tRNAPro


organism: Escherichia coli (strain K12)

substrate_name: tRNA(Cys)


organism: Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)


organism: Halobacterium sp.

substrate_name: tRNACys


substrate_name: ATP; tRNA(Gly); Glycine


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: tRNA(Gly) (at 25 degrees Celsius)


organism: Staphylococcus aureus

substrate_name: tRNAGly


organism: Deinococcus radiodurans

substrate_name: ATP; L-Proline; tRNA(Pro)


mutation_signature: C-terminal deletion mutant


organism: Vigna radiata var. radiata

substrate_name: Unknown


organism: Canavalia ensiformis

substrate_name: tRNAArg(ACG)


organism: Cricetulus griseus

substrate_name: tRNA(Arg); L-Arginine; ATP


organism: Pyrococcus horikoshii

substrate_name: tRNAArg


organism: Homo sapiens

substrate_name: tRNA(Phe)


substrate_name: tRNAPhe


organism: Saccharomyces cerevisiae


organism: Caulobacter vibrioides

substrate_name: tRNAHis


substrate_name: ATP


substrate_name: tRNA(His)


organism: Neurospora crassa


organism: Salmonella typhimurium

substrate_name: tRNA(His); ATP; L-Histidine


substrate_name: L-Arginine


organism: Escherichia coli


substrate_name: L-Histidine


substrate_name: L-Glutamine


substrate_name: arginine (ATP-PPi exchange at 37 degrees Celsius)


substrate_name: ATP (ATP-PPi exchange at 37 Celsius)


substrate_name: proline


substrate_name: alanine


substrate_name: cysteine


substrate_name: L-alanine


substrate_name: L-proline


substrate_name: DL-m-tyrosine


substrate_name: L-tyrosine


organism: Methanothermobacter thermautotrophicus

substrate_name: L-cysteine


substrate_name: L-Cysteine


substrate_name: L-Proline


organism: Aquifex aeolicus


organism: Borrelia burgdorferi


organism: Clostridium sticklandii


organism: Aquifex aeolicus (strain VF5)

substrate_name: proline (at 60 degrees Celsius)


substrate_name: cysteine (at 60 degrees Celsius)


organism: Cytophaga hutchinsonii


organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)


organism: Deinococcus radiodurans


substrate_name: glycine


organism: Novosphingobium aromaticivorans


organism: Methanocaldococcus jannaschii


organism: Rhodopseudomonas palustris


organism: Oryctolagus cuniculus


substrate_name: ATP


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)


organism: Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)


substrate_name: L-Glutamate


organism: Thermus thermophilus


organism: Methanococcus maripaludis


organism: Homo sapiens

substrate_name: L-Phenylalanine


organism: Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)


organism: Mycolicibacterium smegmatis

substrate_name: Arg


substrate_name: tubercidin 5'-triphosphate


organism: Escherichia coli (strain K12)

substrate_name: Glu


organism: Escherichia coli

substrate_name: Alanine


substrate_name: L-glutamine


substrate_name: L-glutamate


substrate_name: L-Phe


substrate_name: His


substrate_name: tRNAPro


substrate_name: L-alanine


substrate_name: L-proline


organism: Bombyx mori

substrate_name: Gly


mutation_signature: N55-truncation mutant


substrate_name: tRNAGly

mutation_signature: N55-truncation mutant enzyme


substrate_name: tRNAArg


substrate_name: ATP


substrate_name: Pro


substrate_name: tRNAHis


substrate_name: L-histidine


substrate_name: L-arginine


mutation_signature: Δ1


organism: Phaseolus vulgaris

substrate_name: L-Pro


substrate_name: L-azetidine-2-carboxylic acid


substrate_name: thiazolidine-4-carboxylic acid


substrate_name: N-methylglycine


substrate_name: N-Methyl-L-alanine


organism: Plasmodium falciparum

substrate_name: L-phenylalanine


substrate_name: Unknown


substrate_name: tRNAPhe


organism: Methanosarcina mazei


substrate_name: synthetic tRNAHis A-1


substrate_name: tRNACys


substrate_name: L-cysteine


mutation_signature: truncated enzyme form NcatHisRS / aminoacylation truncated enzyme form NcatHisRS


mutation_signature: truncated enzyme form NcatHisRS / ATP-diphosphate exchange truncated enzyme form NcatHisRS


substrate_name: His


substrate_name: ATP

mutation_signature: Unknown


substrate_name: L-glutamine


mutation_signature: truncated mutant PheRSDELTAB2A294G


substrate_name: tRNAHis


substrate_name: tRNAGln


substrate_name: L-alanine


substrate_name: L-proline


mutation_signature: recombinant His-tagged deletion mutant


organism: Methanosarcina barkeri

substrate_name: 2-Chloroadenosine 5'-triphosphate


substrate_name: N6-methyladenosine 5'-triphosphate


substrate_name: 3'-Deoxyadenosine 5'-triphosphate


organism: Saccharomyces cerevisiae

mutation_signature: full-length enzyme and truncated enzyme full-length enzyme and truncated enzyme


substrate_name: Gln


organism: Cricetulus griseus

substrate_name: L-arginine


substrate_name: tRNAArg


substrate_name: L-glutamate


substrate_name: Arg


substrate_name: tRNAGly


substrate_name: Gly


substrate_name: tubercidin 5'-triphosphate


substrate_name: 2'-deoxyadenosine 5'-triphosphate


substrate_name: selenocysteine


substrate_name: L-cysteine


substrate_name: L-tyrosine


substrate_name: DL-m-tyrosine


substrate_name: L-proline


organism: Pseudomonas aeruginosa

substrate_name: tRNAPhe


substrate_name: ATP


substrate_name: L-phenylalanine


substrate_name: tRNAPro


substrate_name: tRNAHis


substrate_name: L-histidine


organism: Gallus gallus


substrate_name: Phe


organism: Rattus norvegicus

substrate_name: Arg


substrate_name: tRNAArg


substrate_name: RNA microhelix


substrate_name: Pro


substrate_name: gamma-thiaproline


substrate_name: Cys


substrate_name: diphosphate


mutation_signature: truncated DELTANhcArgRS / truncated DELTANhcArgRS


substrate_name: L-arginine


substrate_name: His


substrate_name: 2'-deoxyadenosine 5'-triphosphate


substrate_name: 3'-Deoxyadenosine 5'-triphosphate


substrate_name: L-tyrosine


substrate_name: L-phenylalanine


organism: Salmonella enterica subsp. enterica serovar Typhimurium


substrate_name: ATP


substrate_name: tRNAGly


substrate_name: Gly


organism: Streptococcus pneumoniae

substrate_name: tRNAPhe


organism: Borreliella burgdorferi

substrate_name: L-cysteine


substrate_name: L-proline


organism: Saccharomyces pastorianus

substrate_name: tRNAArgIII


substrate_name: Arg


organism: Vigna radiata var. radiata

substrate_name: selenocysteine


substrate_name: Cys


substrate_name: 2-aminobutyric acid


organism: Cricetulus sp.

substrate_name: tRNAArg


organism: Escherichia coli


substrate_name: Glu


organism: Thermus thermophilus

substrate_name: tRNAGlu


substrate_name: L-Glu


substrate_name: 2'-deoxyadenosine 5'-triphosphate


organism: Glycine max

substrate_name: L-arginine


substrate_name: L-canavanine


organism: Geobacillus stearothermophilus


substrate_name: Phe


substrate_name: ATP


organism: Methanothermobacter thermautotrophicus


organism: Homo sapiens

substrate_name: L-alanine


organism: Mus musculus


substrate_name: Unknown


organism: Oryctolagus cuniculus

substrate_name: tRNAHisII


substrate_name: L-His


organism: Phaseolus vulgaris


organism: Plasmodium falciparum

substrate_name: tRNAGln


organism: Rhodopseudomonas palustris

substrate_name: L-cysteine


substrate_name: L-proline


organism: Saccharomyces cerevisiae


enzyme_display_name: threonine--tRNA ligase

substrate_name: tRNAThr


substrate_name: tRNAHis


substrate_name: tRNAGly


substrate_name: glycine


substrate_name: L-glutamine


substrate_name: L-phenylalanine


substrate_name: tubercidin 5'-triphosphate


enzyme_display_name: UniProt Q8PWY1

organism: Methanosarcina mazei

substrate_name: N-acetyl-L-lysine


organism: Staphylococcus aureus


substrate_name: tRNAGlu mutant C36G


enzyme_display_name: D-alanine--(R)-lactate ligase

substrate_name: D-lactate


substrate_name: D-Ala


enzyme_display_name: glutamate--tRNA(Gln) ligase


substrate_name: L-Glu


substrate_name: ATP


enzyme_display_name: pyrrolysine--tRNA(Pyl) ligase


substrate_name: L-glutamate


enzyme_display_name: aspartate--tRNA(Asn) ligase

organism: Halalkalibacterium halodurans

substrate_name: tRNAAsn


organism: Thermosynechococcus vestitus

substrate_name: tRNAGln


organism: Bacillus subtilis


organism: Enterococcus faecalis


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: L-aspartate (at 37 degrees Celsius)


substrate_name: ATP (at 37 degrees Celsius)


organism: Escherichia coli


substrate_name: L-tyrosine


organism: Chlamydia trachomatis

substrate_name: L-Aspartate; tRNA(Asn); ATP


substrate_name: L-Glutamate; ATP; tRNA(Gln)


substrate_name: tRNA(Glu)


enzyme_display_name: serine--tRNA ligase

organism: Methanothermobacter thermautotrophicus

substrate_name: tRNASer


substrate_name: tRNAArg


organism: Mycobacterium tuberculosis


substrate_name: tRNAGlu


substrate_name: tRNA(Asp) (at 37 degrees Celsius)


organism: Desulfitobacterium hafniense

substrate_name: tRNAPyl


substrate_name: more


organism: Methanosarcina barkeri

substrate_name: L-Pyrrolysine; ATP


enzyme_display_name: O-phosphoserine--tRNA ligase

organism: Methanocaldococcus jannaschii

substrate_name: tRNA(Cys); ATP; O-Phospho-L-serine


substrate_name: tRNACys


enzyme_display_name: asparagine--tRNA ligase

organism: Escherichia coli (strain K12)

substrate_name: ATP


organism: Deinococcus radiodurans

substrate_name: tRNAAsp


organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)

substrate_name: tRNA(Asp)


organism: Helicobacter pylori (strain ATCC 700392 / 26695)


organism: Methanosarcina mazei

substrate_name: O-phospho-L-threonine


substrate_name: O-phospho-L-serine


substrate_name: asparagine


substrate_name: N-acetyl-L-lysine


substrate_name: Asn


substrate_name: L-Pyrrolysine


organism: Vigna radiata var. radiata

substrate_name: S-adenosyl-L-methionine


substrate_name: isoasparagine


organism: Cricetulus griseus

substrate_name: tRNAAsn


substrate_name: L-pyrrolysine


organism: Enterococcus faecium

substrate_name: D-lactate


substrate_name: D-Ala


organism: Helicobacter pylori


organism: Thermus thermophilus


substrate_name: aspartate


organism: Archaeoglobus fulgidus

substrate_name: tRNACys


organism: Plasmodium falciparum


substrate_name: L-asparagine


substrate_name: ATP


substrate_name: L-phenylalanine


substrate_name: L-Glu


organism: Escherichia coli


substrate_name: Unknown


organism: Bacillus subtilis


organism: Bombyx mori


organism: Bdellovibrio bacteriovorus


organism: Bos taurus


substrate_name: Phe


organism: Cricetulus sp.

substrate_name: tRNAArg


substrate_name: Gly


organism: Triticum aestivum

substrate_name: tRNAGlu


substrate_name: Glu


organism: Chlamydomonas reinhardtii


substrate_name: L-alanine


enzyme_display_name: UniProt Q9VCC6

organism: Drosophila melanogaster

substrate_name: lauric acid


substrate_name: linoleic acid


enzyme_display_name: UniProt Q9P2R7

organism: Homo sapiens

substrate_name: succinate


enzyme_display_name: succinate--CoA ligase (GDP-forming)

organism: Blastocystis hominis

substrate_name: GTP


enzyme_display_name: acetate--CoA ligase

organism: Pyrococcus furiosus

substrate_name: acetyl-CoA


substrate_name: CoA


substrate_name: ADP


substrate_name: ATP


substrate_name: phosphate


substrate_name: acetate


substrate_name: ATP; Coenzyme A; Acetate


organism: Saccharomyces cerevisiae

substrate_name: Coenzyme A; ATP; Acetate


substrate_name: Coenzyme A; ATP; Acrylate


organism: Columba livia

substrate_name: GTP; Succinate; Coenzyme A


substrate_name: Succinyl-CoA; GDP; Phosphate


organism: Sus scrofa


substrate_name: GTP; Coenzyme A; Succinate


enzyme_display_name: succinate--CoA ligase (ADP-forming)

organism: Thermococcus kodakarensis


organism: Alcanivorax borkumensis

substrate_name: Itaconate


substrate_name: L-malate


substrate_name: D-Malate


substrate_name: Succinyl-CoA; ADP; Phosphate


substrate_name: Coenzyme A; Succinate; ATP


organism: Escherichia coli K-12

substrate_name: succinate


organism: Calliphoridae

substrate_name: coenzyme A


substrate_name: succinyl-CoA


substrate_name: ADP


substrate_name: ATP


substrate_name: CoA


enzyme_display_name: long-chain-fatty-acid--CoA ligase

organism: Rattus norvegicus

substrate_name: oleate


substrate_name: palmitate


enzyme_display_name: medium-chain acyl-CoA ligase

organism: Pseudomonas aeruginosa


organism: Aedes togoi

substrate_name: acetyl-CoA


organism: Nipponoluciola cruciata

substrate_name: lauric acid


substrate_name: arachidonate


organism: Advenella mimigardefordensis


organism: Methanosarcina acetivorans


organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)

substrate_name: butyrate


substrate_name: propionate


substrate_name: valerate


substrate_name: acetate


organism: Penicillium chrysogenum

substrate_name: phenylacetate


substrate_name: Phenoxyacetate


substrate_name: trans-cinnamic acid


substrate_name: myristic acid


substrate_name: propionic acid


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: CoA (at pH 8 and at 37 degrees Celsius)


substrate_name: palmitic acid (at pH 8 and at 37 degrees Celsius)


substrate_name: ATP (at pH 8 and at 37 degrees Celsius)


substrate_name: 3-oxo-4-cholesten-26-oate (at pH 7.3 and 22 degrees Celsius)


organism: Populus trichocarpa

substrate_name: Sodium acetate


substrate_name: CoA


substrate_name: palmitate


substrate_name: oleate


substrate_name: arachidonate


substrate_name: ATP


substrate_name: butyrate


substrate_name: propionate


substrate_name: valerate


substrate_name: acetate


organism: Arabidopsis thaliana

substrate_name: 16-hydroxypalmitic acid


organism: Bacillus brevis

substrate_name: ATP; Coenzyme A; Phenylalanine


substrate_name: Coenzyme A; ATP; Tyrosine


substrate_name: Coenzyme A; Phenylalanine; ATP


organism: Bacillus subtilis

substrate_name: Coenzyme A; ATP; D-Alanine


substrate_name: ATP; 2,3-Dihydroxybenzoate; Coenzyme A


substrate_name: Acetate; Coenzyme A; ATP


organism: Escherichia coli

substrate_name: Acetate; ATP; Coenzyme A


organism: Methanothrix thermoacetophila


organism: Saccharomyces cerevisiae

substrate_name: Coenzyme A; Acetate; ATP


organism: Salmonella enterica

substrate_name: Propanoate; Coenzyme A; ATP


organism: Bos taurus

substrate_name: ATP (with (R)-lipoate as substrate)


organism: Chromochloris zofingiensis

substrate_name: Sodium acetate


substrate_name: potassium acetate


organism: Lathyrus oleraceus

substrate_name: Unknown


organism: Homo sapiens


organism: Mycobacterium avium


organism: Rattus norvegicus


substrate_name: ATP; Coenzyme A; Palmitate


substrate_name: ATP; Palmitate; Coenzyme A


substrate_name: Palmitate; Coenzyme A; ATP


substrate_name: ATP; Benzoate; Coenzyme A


substrate_name: Coenzyme A; Palmitate; ATP


substrate_name: Coenzyme A; Hexanoate; ATP


substrate_name: ATP; Coenzyme A; Hexanoate


substrate_name: Coenzyme A; Octanoate; ATP


organism: Sus scrofa


organism: Blastocystis sp. subtype 1 (strain ATCC 50177 / NandII)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: Coenzyme A; ATP; Palmitate


substrate_name: Palmitate; ATP; Coenzyme A


substrate_name: palmitate


substrate_name: ATP (Isoform 1)


substrate_name: CoA (Isoform 1)


substrate_name: palmitate (Isoform 1)


substrate_name: oleate (Isoform 1)


substrate_name: arachidonate (Isoform 1)


substrate_name: benzoate


substrate_name: butyrate


substrate_name: decanoate


substrate_name: hexanoate


substrate_name: laurate


substrate_name: phenylacetate


substrate_name: salicylate


substrate_name: ATP


substrate_name: CoA


substrate_name: oleate


substrate_name: arachidonate


substrate_name: 3-oxo-4-cholesten-26-oate (at pH 7.3 and 22 degrees Celsius)


substrate_name: succinate


substrate_name: dodecanoate


substrate_name: Octanoate


substrate_name: Decanoate


substrate_name: octanoic acid


substrate_name: decanoic acid


substrate_name: dodecanoic acid


substrate_name: linoleate


substrate_name: stearate


organism: Thermus thermophilus


substrate_name: GTP


organism: Plasmodium knowlesi

substrate_name: palmitate


substrate_name: stearate (when expressed in bacteria)


substrate_name: oleate (when expressed in bacteria)


substrate_name: linoleate (when expressed in bacteria)


substrate_name: arachidonate (when expressed in bacteria)


organism: Columba livia

substrate_name: succinate (for A-SCS)


substrate_name: CoA (for A-SCS)


substrate_name: succinyl-CoA (for A-SCS)


substrate_name: phosphate (for A-SCS)


substrate_name: ATP


substrate_name: ADP


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: ATP (at pH 7.5 and at 37 degrees Celsius)


substrate_name: CoA (at pH 7.5 and at 37 degrees Celsius)


substrate_name: acetate (at pH 7.5 and at 37 degrees Celsius)


substrate_name: propionate (at pH 7.5 and at 37 degrees Celsius)


substrate_name: glycine (at pH 7.5 and at 37 degrees Celsius)


substrate_name: GTP


substrate_name: GDP


substrate_name: CoA (at pH 8 and at 37 degrees Celsius)


substrate_name: acetate (at pH 8 and at 37 degrees Celsius)


substrate_name: propionate (at pH 8 and at 37 degrees Celsius)


substrate_name: ATP (at pH 8 and at 37 degrees Celsius)


substrate_name: butyrate (at pH 8 and at 37 degrees Celsius)


organism: Mus musculus

substrate_name: acetate


substrate_name: propionate


substrate_name: acetyl-CoA


substrate_name: ATP


substrate_name: CoA


substrate_name: palmitate


substrate_name: oleate


substrate_name: arachidonate


substrate_name: butyrate


substrate_name: hexanoate


substrate_name: octanoate


substrate_name: isobutyrate


substrate_name: (R)-lipoate with ATP as phosphate donor


substrate_name: ATP (with hexanoate as substrate)


substrate_name: stearate (when expressed in bacteria)


substrate_name: linoleate (when expressed in bacteria)


organism: Methanosarcina acetivorans


substrate_name: myristate


enzyme_display_name: olefin beta-lactone synthetase

organism: Stenotrophomonas maltophilia

substrate_name: (2S,3R)-2-hexyl-3-hydroxydecanoic acid


organism: Stenotrophomonas maltophilia (strain K279a)


substrate_name: hexadecanoate (palmitate)


substrate_name: cholate


organism: Escherichia coli (strain K12)

substrate_name: ATP (at pH 8.5 and 37 degrees Celsius)


substrate_name: CoA (at pH 8.5 and 37 degrees Celsius)


substrate_name: acetate (at pH 8.5 and 37 degrees Celsius)


substrate_name: (9Z)-octadecenoate (oleate)


substrate_name: succinate


substrate_name: CoA


substrate_name: ATP


substrate_name: GTP


substrate_name: palmitic acid (at pH 7.5)


organism: Arabidopsis thaliana


substrate_name: Butyrate


substrate_name: Isobutyrate


substrate_name: acetate


substrate_name: propionate


substrate_name: valerate


substrate_name: Heptanoate


substrate_name: hexanoate


substrate_name: Octanoate


substrate_name: chenodeoxycholic acid


substrate_name: butyrate


organism: Methanothermobacter thermautotrophicus


organism: Brassica napus


substrate_name: tetradecanoate


substrate_name: hexadecanoate


substrate_name: (6Z,12Z, 15Z)-octadecatrienoate


substrate_name: octadecanoate


substrate_name: dodecanoate


organism: Salmonella enterica

substrate_name: ATP


substrate_name: CoA


organism: Rattus norvegicus


substrate_name: palmitate


organism: Escherichia coli

substrate_name: Undecanoate


substrate_name: palmitoleate


substrate_name: Pentadecanoate


substrate_name: tridecanoate


substrate_name: heptadecanoate


substrate_name: hexanoate


substrate_name: Heptanoate


substrate_name: Oleate


substrate_name: stearate


substrate_name: myristate


substrate_name: laurate


substrate_name: Octanoate


substrate_name: Decanoate


organism: Paecilomyces variotii


substrate_name: Butyrate


substrate_name: pentanoate


substrate_name: Isopentanoate


substrate_name: Isobutyrate


substrate_name: propionate


substrate_name: CoA


substrate_name: succinyl-CoA


substrate_name: ATP


substrate_name: ADP


substrate_name: phosphate


substrate_name: succinate


organism: Pigeon

substrate_name: GDP


substrate_name: GTP


organism: Escherichia coli K-12


substrate_name: D-malate


substrate_name: Itaconate


substrate_name: L-malate


organism: Yarrowia lipolytica


substrate_name: dephospho-CoA


substrate_name: pantetheine


organism: Archaeoglobus fulgidus

substrate_name: Butyrate


substrate_name: acetate


organism: Alcanivorax borkumensis


organism: Acetobacter aceti


substrate_name: propanoate


substrate_name: acetyl-CoA


organism: Bradyrhizobium japonicum


substrate_name: CoA


substrate_name: dATP


organism: Advenella mimigardefordensis


substrate_name: ATP


organism: Plasmodium falciparum


substrate_name: propionate


organism: Mus musculus

substrate_name: n-tetracosanoic acid


substrate_name: palmitate


organism: Cereibacter sphaeroides


substrate_name: Acrylate


enzyme_display_name: L-3-cyanoalanine synthase

organism: Spinacia oleracea

substrate_name: NaCN


substrate_name: succinate


organism: Bos taurus

substrate_name: benzoate


substrate_name: GTP


substrate_name: Unknown


organism: Methanothrix thermoacetophila


organism: Homo sapiens


organism: Rattus norvegicus


substrate_name: linolenate


substrate_name: palmitoleate


substrate_name: linoleate


organism: Nitrosomonas europaea


organism: Pseudomonas aeruginosa


substrate_name: oleic acid


substrate_name: coenzyme A


organism: Oryctolagus cuniculus

substrate_name: CoA


substrate_name: acetate


organism: Penicillium chrysogenum


substrate_name: ATP


organism: Ovis aries


substrate_name: Butyrate


substrate_name: propanoate


organism: Saccharomyces cerevisiae


substrate_name: oleate


organism: Sus scrofa

substrate_name: Octanoate


organism: Dunaliella tertiolecta

substrate_name: potassium acetate


substrate_name: Sodium acetate


organism: Drosophila melanogaster

substrate_name: lauric acid


substrate_name: linoleic acid


organism: Salmonella enterica


organism: Geobacillus thermodenitrificans

substrate_name: caproate


substrate_name: palmitate


substrate_name: acetyl-CoA


substrate_name: tripolyphosphate


substrate_name: GTP


substrate_name: succinate


substrate_name: CoA


organism: Glycine max


organism: Methanothrix soehngenii


substrate_name: acetate


substrate_name: fluoroacetate


substrate_name: ATP


organism: Caulobacter vibrioides

substrate_name: octadecanoate


organism: Bos taurus


substrate_name: Unknown


substrate_name: Acrylate


enzyme_display_name: phenylalanine--tRNA ligase

organism: Enterococcus faecalis

substrate_name: L-Phe


enzyme_display_name: arginine--tRNA ligase

organism: Escherichia coli

substrate_name: L-arginine


enzyme_display_name: glutamate--tRNA ligase

substrate_name: tRNAGlu


enzyme_display_name: UniProt Q941M3

organism: Populus tomentosa

substrate_name: cinnamate


substrate_name: ferulate


substrate_name: caffeate


enzyme_display_name: 6-carboxyhexanoate-CoA ligase

organism: Ectopseudomonas mendocina


organism: Priestia megaterium

substrate_name: heptanedioate


enzyme_display_name: UniProt O67575

organism: Aquifex aeolicus


enzyme_display_name: UniProt P53559

organism: Bacillus subtilis


substrate_name: Glutarate


substrate_name: suberate


substrate_name: adipate


substrate_name: Octanoate


substrate_name: Heptanoate


substrate_name: benzofuranylalanine


enzyme_display_name: proline--tRNA ligase

substrate_name: ATP


substrate_name: Butyrate


enzyme_display_name: glutamine--tRNA ligase

substrate_name: Gln


enzyme_display_name: 4-coumarate--CoA ligase

organism: Arabidopsis thaliana

substrate_name: 4-Coumarate; Coenzyme A; ATP


substrate_name: Coenzyme A; ATP; Sinapate


organism: Pueraria montana var. lobata


substrate_name: trans-cinnamate


organism: Sorbus aucuparia


enzyme_display_name: acetate--CoA ligase (ADP-forming)

organism: Pyrococcus furiosus

substrate_name: Phosphate; ADP; Acetyl-CoA


substrate_name: ADP; Acetyl-CoA; Phosphate


substrate_name: Isobutanoate


substrate_name: GTP


substrate_name: ADP; Phosphate; Acetyl-CoA


substrate_name: ADP


substrate_name: phenylacetic acid


substrate_name: Acetyl-CoA


substrate_name: Acetate


substrate_name: GDP


substrate_name: Phosphate


substrate_name: Phenylacetyl-CoA


substrate_name: Phosphate; Acetyl-CoA; ADP


substrate_name: ATP


substrate_name: Coenzyme A


substrate_name: phenylacetyl-CoA


substrate_name: isobutyryl-CoA


substrate_name: Isobutyrate


substrate_name: acetyl-CoA


substrate_name: CoA


substrate_name: indoleacetate


substrate_name: acetate


substrate_name: phenylacetate


substrate_name: ADP


substrate_name: phosphate


substrate_name: GTP


organism: Thermococcus kodakarensis


substrate_name: CoASH


substrate_name: sinapoate


substrate_name: isoferulate


organism: Chloroflexus aurantiacus


enzyme_display_name: acid--CoA ligase (GDP-forming)

organism: Rattus norvegicus

substrate_name: Octanoate


substrate_name: Butyrate


substrate_name: oleate


substrate_name: palmitate


enzyme_display_name: biotin--CoA ligase

organism: Mycoplana sp.


substrate_name: (+/-)-dethiobiotin


substrate_name: (+)-biotin


substrate_name: DL-actithiazic acid


substrate_name: ATP


organism: Piper nigrum

substrate_name: cinnamate


substrate_name: ferulate


substrate_name: piperate


organism: Oryza sativa


substrate_name: caffeate


substrate_name: sinapate


organism: Physcomitrium patens


enzyme_display_name: cholate--CoA ligase

organism: Ophiodon elongatus

substrate_name: lithocholate


substrate_name: cholate


substrate_name: deoxycholate


substrate_name: chenodeoxycholate


enzyme_display_name: oxalate--CoA ligase

substrate_name: oxalate


organism: Glycine max


organism: Populus x canadensis


substrate_name: sinapoate


organism: Forsythia suspensa

substrate_name: CoA


organism: Giardia duodenalis

substrate_name: acetyl-CoA


substrate_name: ADP


substrate_name: phosphate


organism: Pyrobaculum aerophilum

substrate_name: isobutyryl-CoA


substrate_name: phenylacetyl-CoA


organism: Erythrina crista-galli


organism: Ruta graveolens


substrate_name: cinnamate


substrate_name: dADP


organism: Salix babylonica

substrate_name: ferulate


organism: Phycomyces blakesleeanus

substrate_name: acetate


substrate_name: propionate


organism: Eubacterium sp.


substrate_name: ATP


organism: unidentified archaeon


organism: Cavia porcellus

substrate_name: cholate


organism: Entamoeba histolytica


organism: Escherichia coli

substrate_name: tRNAArg


organism: Oryza sativa subsp. japonica


substrate_name: caffeate


substrate_name: sinapate


organism: Thermococcus kodakarensis

substrate_name: Isobutyrate


substrate_name: CoA


substrate_name: thioglycolate


organism: Arabidopsis thaliana

substrate_name: trans-cinnamate


substrate_name: p-coumarate


organism: Populus tomentosa


organism: Solanum lycopersicum


organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

substrate_name: phenylacetyl-CoA (at 80 degrees Celsius)


substrate_name: ATP (at 80 degrees Celsius)


substrate_name: GTP (at 80 degrees Celsius)


substrate_name: CoA (at 80 degrees Celsius)


substrate_name: acetate (at 80 degrees Celsius)


substrate_name: isobutyrate (at 80 degrees Celsius)


substrate_name: indoleacetate (at 80 degrees Celsius)


substrate_name: phenylacetate (at 80 degrees Celsius)


substrate_name: ADP (at 80 degrees Celsius)


substrate_name: GDP (at 80 degrees Celsius)


substrate_name: phosphate (at 80 degrees Celsius)


substrate_name: acetyl-CoA (at 80 degrees Celsius)


substrate_name: isobutyryl-CoA (at 80 degrees Celsius)


substrate_name: ADP


substrate_name: acetyl-CoA


substrate_name: phosphate


substrate_name: acetate


substrate_name: ATP


substrate_name: CoA


substrate_name: ATP (at 80 degrees Celsius)


substrate_name: GTP (at 80 degrees Celsius)


substrate_name: CoA (at 80 degrees Celsius)


substrate_name: acetate (at 80 degrees Celsius)


substrate_name: isobutyrate (at 80 degrees Celsius)


organism: Physcomitrium patens


substrate_name: caffeate


substrate_name: cinnamate


substrate_name: ferulate


organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

substrate_name: phenylacetyl-CoA


substrate_name: phenylacetate


organism: Medicago truncatula

substrate_name: oxalate


substrate_name: 4-Coumarate; Coenzyme A; ATP


substrate_name: ATP; 4-Coumarate; Coenzyme A


substrate_name: ATP; Coenzyme A; 3,4-Dihydroxy-trans-cinnamate


substrate_name: Coenzyme A; ATP; 4-Coumarate


organism: Archaeoglobus fulgidus

substrate_name: Phosphate; ADP; Acetyl-CoA


organism: Petunia hybrida

substrate_name: trans-cinnamic acid


substrate_name: 4-coumaric acid


substrate_name: caffeic acid


substrate_name: CoA


substrate_name: ferulic acid


substrate_name: benzoic acid


organism: Methanocaldococcus jannaschii

substrate_name: Acetyl-CoA; Phosphate; ADP


organism: Rattus norvegicus

substrate_name: 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate; ATP; Coenzyme A


organism: Nicotiana tabacum


substrate_name: sinapinate


substrate_name: caffeate


substrate_name: ferulate


organism: Anthoceros agrestis

substrate_name: isoferulate


substrate_name: cinnamate


substrate_name: ATP


organism: Plagiochasma appendiculatum


substrate_name: Unknown


substrate_name: adenosine 5'-tetraphosphate


organism: Glycine max


organism: Entamoeba histolytica

substrate_name: phosphate


substrate_name: ADP


substrate_name: GDP


substrate_name: GTP


substrate_name: acetyl-CoA


substrate_name: acetate


substrate_name: CoA


organism: Homo sapiens


organism: Arabidopsis thaliana


enzyme_display_name: 6-carboxyhexanoate--CoA ligase

organism: Bacillus subtilis

substrate_name: Octanoate


substrate_name: Heptanoate


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


enzyme_display_name: malate--CoA ligase

organism: Sus scrofa


substrate_name: tetradecanoate


substrate_name: propionyl-CoA


substrate_name: propionate


substrate_name: caffeate


substrate_name: cinnamate


substrate_name: ferulate


substrate_name: ATP


organism: Columba livia

substrate_name: succinate (for A-SCS)


substrate_name: CoA (for A-SCS)


substrate_name: succinyl-CoA (for A-SCS)


substrate_name: phosphate (for A-SCS)


substrate_name: ADP


substrate_name: sinapinate


organism: Solanum lycopersicum

substrate_name: oxalate


organism: Ocimum tenuiflorum


substrate_name: trans-cinnamate


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: acetyl-CoA


substrate_name: phosphate


organism: Lysinibacillus sphaericus

substrate_name: CoASH


substrate_name: pimelate


substrate_name: sinapate


organism: Clostridium scindens (strain JCM 10418 / VPI 12708)

substrate_name: cholate


organism: Acetobacterium woodii

substrate_name: CoA


substrate_name: caffeate


organism: Vigna umbellata


organism: Lathyrus oleraceus


substrate_name: ATP


substrate_name: hexadecanoate (palmitate)


organism: Pyrococcus furiosus


substrate_name: acetate


substrate_name: succinate


organism: Rattus norvegicus

substrate_name: chenodeoxycholic acid


organism: Nicotiana tabacum


substrate_name: ferulate


organism: Petroselinum crispum

substrate_name: Coenzyme A; 4-Coumarate; ATP


substrate_name: isoferulate


substrate_name: cinnamate


substrate_name: azelate


substrate_name: suberate


substrate_name: Glutarate


substrate_name: adipate


organism: Haloarcula marismortui

substrate_name: ADP


substrate_name: acetyl-CoA


substrate_name: phosphate


organism: Solanum tuberosum


substrate_name: caffeate


substrate_name: p-methoxycinnamate


organism: Thermococcus kodakarensis

substrate_name: thioglycolate


substrate_name: phenylacetate


substrate_name: acetate


substrate_name: Isobutyrate


substrate_name: CoA


substrate_name: ATP


organism: Pinus taeda


substrate_name: ferulate


substrate_name: cinnamate


organism: Arabidopsis thaliana


organism: Haloferax volcanii


organism: Populus tomentosa


organism: Sorbus aucuparia


organism: Pueraria montana var. lobata

substrate_name: trans-cinnamate


organism: Populus trichocarpa


organism: Lysinibacillus sphaericus


substrate_name: heptanedioate


organism: Halococcus saccharolyticus


organism: Populus trichocarpa x Populus deltoides


organism: Populus tremuloides


organism: Aquifex aeolicus


organism: Rattus norvegicus

substrate_name: chenodeoxycholate


substrate_name: oxalate


organism: Escherichia coli

substrate_name: L-glutamine


organism: Corynebacterium amycolatum


organism: Camellia sinensis var. sinensis


substrate_name: L-proline


substrate_name: tRNAArg(ACG)


enzyme_display_name: cysteine--tRNA ligase

substrate_name: L-cysteine


substrate_name: tRNAGlu


substrate_name: L-Glutamine; ATP; tRNA(Gln)


enzyme_display_name: phenylalanine--tRNA ligase

organism: Gallus gallus

substrate_name: 2'-deoxyadenosine 5'-triphosphate


enzyme_display_name: glycine--tRNA ligase


enzyme_display_name: arginine--tRNA ligase

organism: Geobacillus stearothermophilus


enzyme_display_name: propionate--CoA ligase

organism: Ralstonia solanacearum

substrate_name: Acrylate


substrate_name: Butyrate


substrate_name: propionate


substrate_name: CoA


substrate_name: acetate


substrate_name: L-Cysteinyl-tRNACys


organism: Rhodotorula glutinis

substrate_name: linoleic acid


substrate_name: oleic acid


substrate_name: stearic acid


substrate_name: palmitic acid


substrate_name: ATP


enzyme_display_name: [citrate (pro-3S)-lyase] ligase

organism: Clostridium sphenoides

substrate_name: ATP; Citrate (pro-3S)-lyase (thiol form); Acetate


enzyme_display_name: acetoacetate--CoA ligase

organism: Zoogloea ramigera

substrate_name: Coenzyme A; Acetoacetate; ATP


substrate_name: acetoacetate


organism: Synechococcus elongatus


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: hexanoic acid


substrate_name: decanoic acid


substrate_name: lauric acid


organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)

substrate_name: butyrate


substrate_name: valerate


substrate_name: propionate


organism: Sulfurisphaera tokodaii


substrate_name: decanoate


substrate_name: dodecanoate


substrate_name: tetradecanoate


organism: Humulus lupulus


substrate_name: CoA


organism: Vibrio harveyi

substrate_name: palmitoleic acid


substrate_name: Unknown


substrate_name: MbtL-holo


organism: Lacrimispora sphenoides

substrate_name: citrate lyase


organism: Rubrivivax gelatinosus


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


substrate_name: hexadecanoate


substrate_name: ATP


enzyme_display_name: arachidonate--CoA ligase

organism: Homo sapiens


organism: Rattus norvegicus


substrate_name: palmitate


substrate_name: oleate


substrate_name: arachidonate


organism: Mycobacterium marinum (strain ATCC BAA-535 / M)


substrate_name: Acetoacetate; ATP; Coenzyme A


substrate_name: Coenzyme A; Acetate; ATP


substrate_name: acyl-carrier protein


substrate_name: arachidonate (Isoform 1)


substrate_name: acetate


substrate_name: butyrate


substrate_name: propionate


organism: Mus musculus


organism: Chloroflexus aurantiacus


substrate_name: NADPH


substrate_name: CoA


substrate_name: ATP (Isoform 1)


substrate_name: CoA (Isoform 1)


substrate_name: palmitate (Isoform 1)


substrate_name: oleate (Isoform 1)


substrate_name: linoleate (when expressed in bacteria)


substrate_name: arachidonate (when expressed in bacteria)


substrate_name: stearate (when expreesed in bacteria)


substrate_name: linoleate (when expreesed in bacteria)


substrate_name: stearate


substrate_name: oleate


substrate_name: linoleate


substrate_name: arachidonate


substrate_name: isobutyrate


substrate_name: ATP


substrate_name: acetate


organism: Ralstonia solanacearum


substrate_name: Coenzyme A


substrate_name: hexadecanoate (palmitate)


substrate_name: palmitic acid (at pH 7.5)


substrate_name: (9Z)-octadecenoate (oleate)


organism: Salmonella enterica

substrate_name: ATP; Coenzyme A; Propanoate


substrate_name: Butyrate


substrate_name: CoA


substrate_name: Acrylate


substrate_name: propionate


organism: Escherichia coli

substrate_name: stearic acid


substrate_name: myristic acid


substrate_name: palmitoleic acid


substrate_name: lauric acid


substrate_name: Decanoic acid


substrate_name: octanoic acid


organism: Metallosphaera sedula


substrate_name: propanoate


substrate_name: ATP


substrate_name: arachidonate


substrate_name: palmitic acid


substrate_name: oleic acid


substrate_name: acetoacetate


organism: Klebsiella aerogenes


substrate_name: acetyl adenylate


substrate_name: acetate


substrate_name: CoA


organism: Oryctolagus cuniculus


organism: Streptomyces lividans


substrate_name: Butyrate


organism: Bos taurus


organism: Cavia porcellus


substrate_name: propionyl-AMP


substrate_name: diphosphate


organism: Geobacillus stearothermophilus

substrate_name: L-arginine


organism: Glycine max

substrate_name: tRNAArg(ACG)


substrate_name: E. coli acyl-carrier protein


organism: Haemophilus influenzae

substrate_name: L-Phe


organism: Sinorhizobium meliloti


enzyme_display_name: glutamate--tRNA ligase

organism: Homo sapiens

substrate_name: tRNAGlu


enzyme_display_name: 4-coumarate--CoA ligase

substrate_name: sinapate


substrate_name: propanoate


substrate_name: Unknown


organism: Helicobacter pylori


enzyme_display_name: succinate--CoA ligase (ADP-forming)

substrate_name: succinate


enzyme_display_name: beta-phosphoglucomutase

organism: Lactobacillus delbrueckii subsp. lactis

substrate_name: beta-D-glucose 1-phosphate


enzyme_display_name: DNA 3'-5' helicase

organism: Lathyrus oleraceus


enzyme_display_name: glutamine synthetase


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: glucose 6-phosphate


enzyme_display_name: oxalate--CoA ligase

organism: Glycine soja

substrate_name: oxalate


enzyme_display_name: cysteine-S-conjugate beta-lyase

organism: Latilactobacillus sakei

substrate_name: L-cysteine


enzyme_display_name: cysteine--tRNA ligase

substrate_name: ATP


enzyme_display_name: peptidylprolyl isomerase

organism: Legionella pneumophila


enzyme_display_name: lactoylglutathione lyase

organism: Leishmania donovani

substrate_name: reduced trypanothione


enzyme_display_name: phenylalanine--tRNA ligase

substrate_name: L-phenylalanine


enzyme_display_name: DNA topoisomerase (ATP-hydrolyzing)


organism: Lathyrus sativus


organism: Leishmania major

substrate_name: alpha-D-glucose 1-phosphate


substrate_name: L-glutamate


organism: Levilactobacillus brevis


enzyme_display_name: L-arabinose isomerase

substrate_name: L-arabinose


organism: Leishmania mexicana mexicana

substrate_name: D-fructose 6-phosphate


enzyme_display_name: triose-phosphate isomerase

organism: Leishmania mexicana


enzyme_display_name: glutamate racemase

organism: Limosilactobacillus fermentum

substrate_name: D-Glu


enzyme_display_name: coproporphyrin ferrochelatase

organism: Listeria monocytogenes


enzyme_display_name: serine racemase

organism: Macrostomum lignano

substrate_name: D-serine


substrate_name: D-glyceraldehyde 3-phosphate


organism: Malus domestica

substrate_name: L-arginine


enzyme_display_name: maltose epimerase

substrate_name: beta-maltose


substrate_name: (R,S)-S-adenosylmethionine


organism: Mesocricetus auratus


enzyme_display_name: UDP-glucose 4-epimerase

organism: Magallana gigas

substrate_name: UDP-alpha-D-galactose


organism: Manihot esculenta


organism: Methanococcus maripaludis

substrate_name: UDP-alpha-D-glucose


organism: Methanocaldococcus jannaschii


enzyme_display_name: lysine 2,3-aminomutase

substrate_name: L-lysine


enzyme_display_name: lysine--tRNA ligase

substrate_name: Escherichia coli tRNALys CNBr-treated


enzyme_display_name: serine--tRNA ligase

organism: Methanosarcina barkeri

substrate_name: tRNASer(GGA)


enzyme_display_name: arachidonate--CoA ligase

organism: Rattus norvegicus

substrate_name: CoA


substrate_name: ATP


substrate_name: L-serine


organism: Metallosphaera sedula


enzyme_display_name: O-phosphoserine--tRNA ligase

substrate_name: tRNACys


enzyme_display_name: proline--tRNA ligase

organism: Methanothermobacter thermautotrophicus

substrate_name: tRNAPro


enzyme_display_name: glutamate--tRNA ligase

substrate_name: tRNAGln(UUG)


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: D-cysteine desulfhydrase

organism: Methylorubrum extorquens

substrate_name: D-cysteine


enzyme_display_name: methylmalonyl-CoA mutase


enzyme_display_name: methionine gamma-lyase

organism: Micromonospora echinospora

substrate_name: L-methionine


enzyme_display_name: medium-chain acyl-CoA ligase

organism: Mus musculus

substrate_name: Unknown


enzyme_display_name: pyrrolysine--tRNA(Pyl) ligase

organism: Methanosarcina thermophila

substrate_name: more


enzyme_display_name: prostaglandin-D synthase


enzyme_display_name: serine racemase

substrate_name: L-aspartate


enzyme_display_name: protoporphyrin ferrochelatase

substrate_name: protoporphyrin IX


enzyme_display_name: glutamine synthetase


enzyme_display_name: lactoylglutathione lyase


enzyme_display_name: plus-end-directed kinesin ATPase


enzyme_display_name: peptidylprolyl isomerase


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


enzyme_display_name: cysteine-S-conjugate beta-lyase


enzyme_display_name: long-chain-fatty-acid--CoA ligase

substrate_name: oleate


enzyme_display_name: alanine racemase

organism: Mycobacterium avium

substrate_name: D-Ala


substrate_name: arachidonate


organism: Mycobacterium tuberculosis

substrate_name: (R)-pantoate


organism: Mimosa pudica

substrate_name: cystathionine


enzyme_display_name: triose-phosphate isomerase

substrate_name: D-glyceraldehyde 3-phosphate


enzyme_display_name: adenylate cyclase

substrate_name: ATP


enzyme_display_name: ribose-5-phosphate isomerase

substrate_name: D-ribose 5-phosphate


enzyme_display_name: DNA 3'-5' helicase


enzyme_display_name: chorismate mutase

substrate_name: chorismate


enzyme_display_name: alpha-methylacyl-CoA racemase


enzyme_display_name: UDP-galactopyranose mutase


enzyme_display_name: 3-oxocholest-4-en-26-oate--CoA ligase


substrate_name: (R)-pristanoyl-CoA


enzyme_display_name: o-succinylbenzoate--CoA ligase


enzyme_display_name: coproporphyrin ferrochelatase

substrate_name: coproporphyrin III


substrate_name: dihydroxyacetone phosphate


organism: Bacillus anthracis


organism: Nitrosopumilus maritimus (strain SCM1)

substrate_name: Unknown


enzyme_display_name: UniProt P14900

organism: Escherichia coli


enzyme_display_name: UniProt P9WJL3


substrate_name: meso-diaminopimelic acid


organism: Pseudomonas aeruginosa (strain UCBPP-PA14)

substrate_name: salicylate


substrate_name: acetate


substrate_name: propionate


enzyme_display_name: isochorismate synthase


organism: Erysipelothrix rhusiopathiae

substrate_name: L-alanine


organism: Thermotoga maritima


substrate_name: D-Lysine


substrate_name: L-ornithine


enzyme_display_name: long-chain fatty acid adenylase/transferase FadD23

substrate_name: palmitate


substrate_name: laurate


enzyme_display_name: dihydrofolate synthase

organism: Serratia indica


substrate_name: L-Glu


organism: Lathyrus oleraceus


substrate_name: ATP


substrate_name: Glu


organism: Lacticaseibacillus casei

substrate_name: D-Ala


organism: Streptococcus pyogenes


enzyme_display_name: enterobactin synthase

organism: Escherichia coli (strain K12)

substrate_name: L-serine


substrate_name: O-acetyl-L-serine


substrate_name: L-beta-chloroalanine


substrate_name: S-methyl-L-cysteine


substrate_name: salicylic acid


substrate_name: 4-aminosalicylic acid


organism: Lactobacillus casei


substrate_name: ATP (in the assay for DHFS activity)


substrate_name: glutamate (in the assay for DHFS activity)


organism: Nitrosopumilus maritimus

substrate_name: CoA


substrate_name: Butanoate


enzyme_display_name: carnosine synthase

organism: Rattus norvegicus

substrate_name: beta-Ala


enzyme_display_name: marinolic acid--CoA ligase

organism: Pseudoalteromonas sp. (strain SANK 73390)

substrate_name: pseudomonic acid A


substrate_name: octanoic acid


substrate_name: salicylate (at pH 7.8 and 25 degrees Celsius)


substrate_name: D-pantetheine (at pH 7.8 and 25 degrees Celsius)


substrate_name: D-Glu


substrate_name: UDP-N-acetylmuramoyl-L-alanine


organism: Pseudoalteromonas sp. SANK 73390

substrate_name: pseudomonic acid C


substrate_name: 4,5-dihydroisochorismate (at pH 7 and 37 degrees Celsius)


source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


organism: Mycobacterium tuberculosis


organism: Enterococcus faecalis


organism: Haemophilus influenzae


organism: Staphylococcus aureus


organism: Escherichia coli


organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)


organism: Gallus gallus

substrate_name: L-Histidine; ATP; beta-Alanine


organism: Homo sapiens

substrate_name: L-Histidine; beta-Alanine; ATP


organism: Mus musculus


substrate_name: ATP; L-Histidine; beta-Alanine


substrate_name: ATP; L-Glutamate; Dihydropteroate


organism: Plasmodium falciparum

substrate_name: Unknown


organism: Nostoc sp. PCC 7120 = FACHB-418

substrate_name: DL-meso-diaminopimelic acid


organism: Physcomitrium patens


substrate_name: phosphopantetheinylated EntB


substrate_name: D-Glutamate


substrate_name: ATP


substrate_name: beta-Alanine


substrate_name: L-histidine


substrate_name: L-lysine


substrate_name: L-ornithine


substrate_name: N-methylhistidine


organism: Erysipelothrix rhusiopathiae


substrate_name: L-alanine


organism: Escherichia coli (strain K12)


substrate_name: tetrahydrofolate


substrate_name: beta-alanine


substrate_name: dihydropteroate


substrate_name: glutamate


substrate_name: isochorismate (at pH 7 and 37 degrees Celsius)


substrate_name: meso-diaminopimelate


substrate_name: meso-lanthionine


organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)


substrate_name: D-alanyl-D-alanine


substrate_name: D-glutamate


mutation_signature: N-terminal deletion mutant


substrate_name: UDP-MurNAc-L-Ala-D-Glu


substrate_name: ATP


substrate_name: beta-Alanine


organism: Bacillus cereus


substrate_name: UDP-N-MurNAc-L-Ala-D-Glu


substrate_name: Glu


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


substrate_name: meso-diaminopimelic acid


organism: Pseudomonas aeruginosa


substrate_name: UDP-N-acetylmuramoyl-L-Ala


substrate_name: D-Glu


organism: Corynebacterium sp.


substrate_name: L-Glu


organism: Neisseria gonorrhoeae


substrate_name: D-Alanyl-D-alanine


substrate_name: D-Alanyl-D-lactate


substrate_name: D-Alanyl-D-methionine


substrate_name: D-Alanyl-D-phenylalanine


substrate_name: L-Histidine; ATP; beta-Alanine


substrate_name: L-His


organism: Acinetobacter baumannii

substrate_name: Unknown


substrate_name: L-Ser


enzyme_display_name: glutamine--tRNA ligase

substrate_name: L-glutamine


substrate_name: ATP


enzyme_display_name: isoleucine--tRNA ligase

substrate_name: L-isoleucine


substrate_name: chorismate


enzyme_display_name: steroid Delta-isomerase


enzyme_display_name: acetate--CoA ligase (ADP-forming)

organism: Archaeoglobus fulgidus

substrate_name: ADP


substrate_name: acetyl-CoA


substrate_name: phosphate


enzyme_display_name: 4-chlorobenzoate--CoA ligase

organism: Arthrobacter sp.


substrate_name: CoA


enzyme_display_name: NAD(P)H-hydrate epimerase

organism: Arabidopsis thaliana


enzyme_display_name: phosphoglucosamine mutase

organism: Methanococcus maripaludis

substrate_name: alpha-D-glucose 1-phosphate


substrate_name: alpha-D-glucosamine 1-phosphate


substrate_name: UDP-N-acetyl-D-glucosamine


organism: Homo sapiens

substrate_name: dehydroepiandrosterone


organism: Escherichia coli

substrate_name: D-Glu


substrate_name: isochorismate


substrate_name: UDP-N-MurNAc-L-Ala-D-Glu


substrate_name: meso-lanthionine


substrate_name: UDP-N-acetylmuramoyl-L-Ala


substrate_name: UDP-N-acetylmuramoyl-L-alanine


enzyme_display_name: chorismate mutase

organism: Mycobacterium tuberculosis


enzyme_display_name: glutamate racemase

substrate_name: Unknown


substrate_name: D-glutamate


substrate_name: UDP-N-acetylmuramoyl L-alanine


substrate_name: ATP


enzyme_display_name: D-alanine--D-alanine ligase


enzyme_display_name: methionine--tRNA ligase

substrate_name: tRNAMet


organism: Mycolicibacterium smegmatis

substrate_name: L-cysteine


enzyme_display_name: L-arabinose isomerase

substrate_name: L-arabinose


enzyme_display_name: prokaryotic ubiquitin-like protein ligase

substrate_name: [IdeR]-L-lysine


enzyme_display_name: adenylate cyclase

organism: Mytilus galloprovincialis


enzyme_display_name: glutamine synthetase

substrate_name: Glu


enzyme_display_name: maltose alpha-D-glucosyltransferase

organism: Myxococcus sp. V11

substrate_name: maltose


organism: Neurospora crassa


enzyme_display_name: glucose-6-phosphate isomerase

organism: Oryctolagus cuniculus

substrate_name: fructose 6-phosphate


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


enzyme_display_name: 4-coumarate--CoA ligase

organism: Nicotiana tabacum

substrate_name: 4-coumaric acid


enzyme_display_name: inositol-3-phosphate synthase

organism: Oryza coarctata

substrate_name: D-glucose 6-phosphate


organism: Oryza sativa


enzyme_display_name: cysteine-S-conjugate beta-lyase


enzyme_display_name: lactoylglutathione lyase

organism: Oryza sativa Japonica Group


organism: Nicotiana sylvestris

substrate_name: chorismate


substrate_name: (R)-S-lactoylglutathione


enzyme_display_name: D-cysteine desulfhydrase

substrate_name: D-cysteine


enzyme_display_name: mannose-6-phosphate isomerase

substrate_name: D-mannose 6-phosphate


enzyme_display_name: GDP-mannose 3,5-epimerase

substrate_name: GDP-D-mannose


organism: Ovis aries

substrate_name: Unknown


enzyme_display_name: xylose isomerase

organism: Parabacteroides sp.

substrate_name: alpha-D-xylopyranose


enzyme_display_name: prostaglandin-E synthase

substrate_name: prostaglandin H2


organism: Paramecium tetraurelia


organism: Pediococcus pentosaceus

substrate_name: D-galactose


enzyme_display_name: serine racemase

organism: Penaeus monodon

substrate_name: D-serine


enzyme_display_name: alanine racemase

organism: Peribacillus psychrosaccharolyticus

substrate_name: D-Ala


organism: Phaseolus vulgaris

substrate_name: L-glutamate


enzyme_display_name: L-arabinose isomerase

organism: Parageobacillus thermoglucosidasius


enzyme_display_name: long-chain-fatty-acid--CoA ligase

organism: Photinus pyralis

substrate_name: lauric acid


organism: Paracoccus denitrificans

substrate_name: cystathionine


enzyme_display_name: steroid Delta-isomerase

organism: Bos taurus


enzyme_display_name: adenylate cyclase

organism: Phycomyces blakesleeanus

substrate_name: ATP


enzyme_display_name: leucine--tRNA ligase

substrate_name: Leu-tRNALeu


organism: Piromyces sp. E2


organism: Plasmodium falciparum


enzyme_display_name: chorismate mutase

organism: Physcomitrium patens


enzyme_display_name: tyrosine--tRNA ligase

substrate_name: tRNATyr


organism: Piromyces sp.

substrate_name: D-xylose


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


enzyme_display_name: methylmalonyl-CoA mutase

organism: Propionibacterium freudenreichii subsp. shermanii

substrate_name: succinyl-CoA


enzyme_display_name: glutamate--cysteine ligase

organism: Proteus mirabilis


organism: Pseudomonas aeruginosa

substrate_name: L-cysteine


enzyme_display_name: triose-phosphate isomerase

substrate_name: D-glyceraldehyde 3-phosphate


enzyme_display_name: methionine gamma-lyase

organism: Porphyromonas gingivalis


enzyme_display_name: isochorismate synthase

substrate_name: chorismate


enzyme_display_name: UDP-glucose 4-epimerase

substrate_name: UDP-alpha-D-glucose


enzyme_display_name: phenylalanine--tRNA ligase

organism: Plasmodium vivax

substrate_name: Unknown


enzyme_display_name: 4-hydroxyproline epimerase


enzyme_display_name: anthranilate--CoA ligase


enzyme_display_name: mannose-6-phosphate isomerase

substrate_name: mannose 6-phosphate


enzyme_display_name: alanine racemase


enzyme_display_name: glutamate--tRNA ligase

substrate_name: tRNAGlu


enzyme_display_name: aspartate--tRNA(Asn) ligase

substrate_name: tRNAAsn


substrate_name: D-galactose


substrate_name: mannose 1-phosphate


enzyme_display_name: glutamine--tRNA ligase

substrate_name: tRNAGln


organism: Pseudomonas fluorescens

substrate_name: D-alanine


organism: Pseudomonas putida

substrate_name: L-alanine


enzyme_display_name: 2-hydroxymuconate tautomerase


enzyme_display_name: amino-acid racemase

substrate_name: D-Met


substrate_name: D-mannose 6-phosphate


substrate_name: D-ornithine


substrate_name: L-Ala


enzyme_display_name: maleate isomerase

substrate_name: Maleate


enzyme_display_name: steroid Delta-isomerase

organism: Pseudomonas sp.


enzyme_display_name: muconate cycloisomerase

organism: Pseudomonas reinekei

substrate_name: cis,cis-muconate


enzyme_display_name: prostaglandin-D synthase

organism: Rattus norvegicus


enzyme_display_name: lanosterol synthase


enzyme_display_name: methylmalonyl-CoA epimerase

organism: Pyrococcus horikoshii

substrate_name: methylmalonyl-CoA


enzyme_display_name: alkylmercury lyase

substrate_name: p-chloromercuribenzoic acid


enzyme_display_name: cholate--CoA ligase

substrate_name: cholate


enzyme_display_name: glutamate--cysteine ligase

substrate_name: glutamate


enzyme_display_name: alpha-methylacyl-CoA racemase

substrate_name: (S)-ibuprofenoyl-CoA


substrate_name: Unknown


enzyme_display_name: glutamine synthetase


enzyme_display_name: guanylate cyclase


substrate_name: Prostaglandin H2


enzyme_display_name: selenocysteine lyase


enzyme_display_name: DNA topoisomerase (ATP-hydrolyzing)

substrate_name: ATP


substrate_name: CoA


substrate_name: L-Cys


substrate_name: guanyl-imidodiphosphate


enzyme_display_name: lysine--tRNA ligase

substrate_name: tRNALys


enzyme_display_name: arachidonate--CoA ligase

substrate_name: arachidonate


enzyme_display_name: inositol-3-phosphate synthase

substrate_name: glucose 6-phosphate


enzyme_display_name: glutathione synthase

substrate_name: N-acetyl-L-Cys


enzyme_display_name: long-chain-fatty-acid--CoA ligase

substrate_name: eicosapentaenoate


enzyme_display_name: pancreatic ribonuclease

substrate_name: cyclic 2',3'-UMP


substrate_name: GTP


substrate_name: AMP


enzyme_display_name: leukotriene-C4 synthase

substrate_name: leukotriene A4


substrate_name: D-glucose 6-phosphate


enzyme_display_name: medium-chain acyl-CoA ligase

substrate_name: Butyrate


substrate_name: stearate


enzyme_display_name: adenylate cyclase


enzyme_display_name: prostaglandin-E synthase

substrate_name: Prostaglandin H2


enzyme_display_name: phosphomannomutase

substrate_name: mannose 1-phosphate


substrate_name: Coenzyme A; ATP; Palmitate


enzyme_display_name: triose-phosphate isomerase

organism: Rhipicephalus microplus

substrate_name: D-glyceraldehyde 3-phosphate


enzyme_display_name: serine racemase

substrate_name: L-serine


organism: Rhizobium etli

substrate_name: ATP


enzyme_display_name: chaperonin ATPase

organism: Rhizobium leguminosarum


enzyme_display_name: aldose 1-epimerase

organism: Rhizopus stolonifer

substrate_name: alpha-D-glucose


enzyme_display_name: maleate isomerase

organism: Rhodococcus jostii

substrate_name: Maleate


enzyme_display_name: muconate cycloisomerase


enzyme_display_name: muconolactone Delta-isomerase

organism: Rhodococcus sp. (in: high G+C Gram-positive bacteria)

substrate_name: muconolactone


enzyme_display_name: ribose-5-phosphate isomerase

organism: Rhodospirillum rubrum

substrate_name: D-ribose 5-phosphate


enzyme_display_name: cellobiose epimerase

organism: Roseburia intestinalis

substrate_name: cellobiose


enzyme_display_name: L-cysteate sulfo-lyase

organism: Ruegeria pomeroyi

substrate_name: L-cysteate


organism: Rhodothermus marinus


organism: Ruminococcus albus

substrate_name: lactose


enzyme_display_name: 3-(methylthio)propionate--CoA ligase


organism: Saccharolobus shibatae

substrate_name: maltohexaose


enzyme_display_name: DNA 3'-5' helicase

organism: Saccharolobus solfataricus


enzyme_display_name: aliphatic aldoxime dehydratase

organism: Rhodococcus sp. N-771


enzyme_display_name: aspartate--tRNA ligase

organism: Saccharomyces cerevisiae

substrate_name: tRNAAsp


enzyme_display_name: tyrosine--tRNA ligase

substrate_name: native yeast tRNATyr


enzyme_display_name: glutamate--cysteine ligase

organism: Rattus norvegicus


enzyme_display_name: phenylalanine--tRNA ligase

substrate_name: L-phenylalanine


substrate_name: Glucose 1-phosphate


enzyme_display_name: lactoylglutathione lyase


enzyme_display_name: glutamine synthetase


enzyme_display_name: lanosterol synthase

substrate_name: Unknown


enzyme_display_name: peptidylprolyl isomerase


enzyme_display_name: tetrahydrofolate synthase

organism: Neurospora crassa


substrate_name: glutathione


substrate_name: L-Tyr


enzyme_display_name: glucose-6-phosphate 1-epimerase

substrate_name: beta-D-glucose 6-phosphate


enzyme_display_name: leucine--tRNA ligase

substrate_name: tRNALeu


substrate_name: Glycerate 3-phosphate


enzyme_display_name: glutamate--tRNA ligase

substrate_name: tRNAGlu


organism: Datura inoxia


substrate_name: ATP


substrate_name: L-Glu


organism: Escherichia coli


organism: Homo sapiens

substrate_name: aminopterin


substrate_name: L-Glutamic acid


enzyme_display_name: phosphopentomutase

substrate_name: alpha-D-ribose 1-phosphate


substrate_name: n-1 n-1 n-1 ATP; 10-Formyltetrahydrofolyl L-glutamate; n-1 n-1 n-1 L-Glutamate


organism: Mus musculus


organism: Plasmodium falciparum


organism: Escherichia coli (strain K12)


substrate_name: tetrahydrofolate


organism: Lacticaseibacillus casei


organism: Lactobacillus casei

substrate_name: n-1 n-1 n-1 L-Glutamate; (6R)-5,10-Methylene-5,6,7,8-tetrahydropteroyl-diglutamate; n-1 n-1 n-1 ATP


substrate_name: glutamic acid


organism: Hapsidospora chrysogena

substrate_name: L-aminoadipate


substrate_name: L-valine


enzyme_display_name: UniProt Q5JIZ8

organism: Thermococcus kodakarensis

substrate_name: beta-Alanine


substrate_name: 5,6,7,8-tetrahydrofolic acid


organism: Bos taurus


substrate_name: methotrexate


organism: Sus scrofa


substrate_name: dATP


substrate_name: ITP


substrate_name: UTP


organism: Acinetobacter calcoaceticus

substrate_name: ATP


substrate_name: L-aspartic acid


substrate_name: L-arginine


substrate_name: L-glutamate (isoform 2 at 37 degrees Celsius in the presence of 1 mM ATP and 2 mM L-glutamate)


substrate_name: MgATP (isoform 2 at 37 degrees Celsius in the presence of 1 mM ATP and 2 mM L-glutamate)


substrate_name: pteroylglutamic acid (PteGlu) (isoform 2 at 37 degrees Celsius in the presence of 1 mM ATP and 2 mM L-glutamate)


substrate_name: aminopterin (isoform 2 at 37 degrees Celsius in the presence of 1 mM ATP and 2 mM L-glutamate)


substrate_name: methotrexate (isoform 2, at 37 degrees Celsius in the presence of 10 mM ATP and pH 8.5)


substrate_name: glutamate


substrate_name: UDP-N-acetyl-alpha-D-muramate


enzyme_display_name: dapdiamide synthase

organism: Enterobacter agglomerans

substrate_name: valine


substrate_name: isoleucine


substrate_name: leucine


substrate_name: 5,10-dideazatetrahydrofolic acid


substrate_name: aminopterin


enzyme_display_name: D-alanine--D-serine ligase

organism: Enterococcus casseliflavus

substrate_name: D-serine


substrate_name: D-asparagine


organism: Enterococcus faecalis

substrate_name: CTP


substrate_name: L-cysteine


substrate_name: fumarate


substrate_name: succinate


enzyme_display_name: jasmonoyl--L-amino acid ligase

organism: Arabidopsis thaliana

substrate_name: L-Ile


substrate_name: L-Phe


substrate_name: L-Leu


substrate_name: L-Val


enzyme_display_name: L-2,3-diaminopropanoate--citrate ligase

organism: Staphylococcus aureus

substrate_name: citrate


organism: Geminocystis herdmanii PCC 6308

substrate_name: ATP


substrate_name: D-alanine (at pH 7.5)


substrate_name: D-threonine (at pH 7.5)


substrate_name: D-homoserine (at pH 7.5)


organism: Methanocaldococcus jannaschii

substrate_name: ATP; Coenzyme gamma-F420-2; L-Glutamate


substrate_name: GTP; L-Glutamate; Coenzyme F420-1


enzyme_display_name: [amino-group carrier protein]--L-2-aminoadipate ligase

organism: Thermus thermophilus


enzyme_display_name: tenuazonic acid synthetase

organism: Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

substrate_name: N-acetoacetyl-L-Ile-SNAC (for the KS domain)


enzyme_display_name: beta-tubulin-glutamate ligase

organism: Mus musculus

substrate_name: [beta-tubulin]-L-glutamate


substrate_name: L-glutamate


enzyme_display_name: tubulin-glutamate ligase

organism: Crithidia fasciculata

substrate_name: [alpha/beta-tubulin]-L-glutamate


substrate_name: [modified porcine brain tubulin]-L-glutamate


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: L-lysine (at pH 9.4)


substrate_name: meso-diaminopimelate (at pH 9.4)


substrate_name: L-ornithine (at pH 9.4)


organism: Hapsidospora chrysogena

substrate_name: cysteine


enzyme_display_name: 4-phosphopantoate--beta-alanine ligase

organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: Unknown


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


organism: Escherichia coli (strain K12)


substrate_name: N-beta-fumaramoyl-DAP


enzyme_display_name: L-alanine--L-anticapsin ligase

organism: Bacillus subtilis (strain 168)


organism: Homo sapiens


enzyme_display_name: UniProt P13000

organism: Escherichia coli

substrate_name: (7R,8S)-7,8-diaminopelargonic acid


enzyme_display_name: UniProt P9WPQ5

organism: Mycobacterium tuberculosis


enzyme_display_name: UniProt P0DJQ7

organism: Streptomyces clavuligerus


substrate_name: L-Arg


substrate_name: ATP


enzyme_display_name: tetrahydrofolate synthase

substrate_name: H(2)PteGlu (isoform 2 at 37 degrees Celsius in the presence of 1 mM ATP and 2 mM L-glutamate)


organism: Lacticaseibacillus casei


organism: Neurospora crassa


organism: Synechocystis sp.

substrate_name: [L-Asp(4-L-Arg)]n; L-Aspartate; ATP


enzyme_display_name: coenzyme F420-0:L-glutamate ligase

organism: Methanocaldococcus jannaschii

substrate_name: GTP; Coenzyme F420-0; L-Glutamate


organism: Thermus thermophilus


organism: Arabidopsis thaliana


organism: Bacillus subtilis

substrate_name: L-alanine


substrate_name: L-glutamine


organism: Amycolatopsis lactamdurans

substrate_name: L-cysteine


substrate_name: L-valine


enzyme_display_name: 5-formyltetrahydrofolate cyclo-ligase

organism: Mycoplasmoides pneumoniae


enzyme_display_name: dethiobiotin synthase


substrate_name: CTP


substrate_name: GTP


substrate_name: ITP


substrate_name: UTP


substrate_name: TTP


enzyme_display_name: O-ureido-D-serine cyclo-ligase

organism: Streptomyces lavendulae

substrate_name: D-homocysteine


substrate_name: O-ureido-D-serine


substrate_name: L-phenylalanine


enzyme_display_name: carbapenam-3-carboxylate synthase

organism: Pectobacterium carotovorum


organism: Mus musculus


organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)


organism: Cryptococcus neoformans (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)

substrate_name: phosphoribosyl-amine (at 37 degrees Celsius)


substrate_name: Unknown


substrate_name: 5-FTHF (at pH 6 and 37 degrees Celsius)


organism: Oryctolagus cuniculus


organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)

substrate_name: 5-CHO-THF (at pH 7.3 and 30 degrees Celsius)


substrate_name: ATP


organism: Escherichia coli


organism: Mycobacterium tuberculosis


organism: Streptomyces clavuligerus


organism: Geminocystis herdmanii PCC 6308

substrate_name: L-Asp


organism: Lacticaseibacillus casei

substrate_name: araATP


organism: Escherichia coli (strain K12)

substrate_name: DAPA (at pH 7.5, 37 degrees Celsius)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: DAPA (at pH 8.5 and at 20 degrees Celsius)


organism: Streptococcus pyogenes serotype M1

substrate_name: Glu (at pH 7.3 and 30 degrees Celsius)


organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)


substrate_name: ATP (at 37 degrees Celsius)


substrate_name: glycine (at 37 degrees Celsius)


substrate_name: GTP


substrate_name: CTP


substrate_name: ATPgammaS


substrate_name: dATP


substrate_name: UTP


substrate_name: dTTP


substrate_name: ITP


organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: beta-alanine


substrate_name: L-cysteine


substrate_name: L-valine


substrate_name: L-aminoadipate


organism: Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)


organism: Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

substrate_name: isoleucine


substrate_name: acetoacetyl-CoA


substrate_name: ATP


organism: Arabidopsis thaliana


substrate_name: 5-CHO-THF-Glu3 (at pH 7.3 and 30 degrees Celsius)


substrate_name: 5-CHO-THF (at pH 7.3 and 30 degrees Celsius)


substrate_name: Unknown


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


enzyme_display_name: dapdiamide synthase

organism: Pantoea agglomerans


organism: Homo sapiens


substrate_name: fumarate


substrate_name: succinate


organism: Mycoplasma pneumoniae


organism: Streptomyces lavendulae

substrate_name: D-homocysteine


substrate_name: O-ureido-D-serine


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: L-arginine


organism: Methanocaldococcus jannaschii

substrate_name: coenzyme gamma-F420-2


organism: Geminocystis herdmanii (strain PCC 6308)

substrate_name: L-aspartic acid


organism: Streptomyces clavuligerus


enzyme_display_name: D-alanine--D-serine ligase

organism: Enterococcus casseliflavus


enzyme_display_name: jasmonoyl--L-amino acid ligase

substrate_name: (-)-jasmonate


organism: Bacillus cereus


organism: Hapsidospora chrysogena


organism: Escherichia coli


substrate_name: 5,6,7,8-tetrahydrofolic acid


substrate_name: L-Glu


organism: Lacticaseibacillus casei


organism: Bacillus subtilis

substrate_name: L-alanine


substrate_name: L-phenylalanine


substrate_name: L-Ala-D-Glu


substrate_name: L-Ala-gamma-D-Glu-L-Lys


substrate_name: L-Ala-gamma-D-Glu-L-Lys-D-Ala


substrate_name: ATP


substrate_name: UDP-N-alpha-D-acetylmuramate


substrate_name: methotrexate


substrate_name: Glu


organism: Mycobacterium tuberculosis


substrate_name: succinate


substrate_name: fumarate


substrate_name: L-valine


substrate_name: L-isoleucine


substrate_name: L-leucine


substrate_name: TTP


substrate_name: GTP


substrate_name: UTP


substrate_name: CTP


substrate_name: ITP


organism: Salmonella enterica


organism: Lysinibacillus sphaericus


enzyme_display_name: tubulin--tyrosine ligase

organism: Bos taurus

substrate_name: untyrosinated tubulin


substrate_name: L-Tyr


enzyme_display_name: N-acetylaspartylglutamate synthase

organism: Mus musculus

substrate_name: N-acetyl-L-aspartate


substrate_name: ATP


substrate_name: L-glutamate


substrate_name: citrate


substrate_name: L-glutamine


substrate_name: L-alanine


substrate_name: (7R,8S)-7,8-diaminopelargonic acid


organism: Lathyrus oleraceus


substrate_name: L-Glu


organism: Homo sapiens


substrate_name: aminopterin


substrate_name: L-Phe


substrate_name: tyramine


organism: Penicillium chrysogenum

substrate_name: L-aminoadipate


substrate_name: L-cysteine


substrate_name: L-valine


substrate_name: ATPgammaS


organism: Oryctolagus cuniculus


substrate_name: CTP


substrate_name: UTP


substrate_name: (6RS)-5,6,7,8-tetrahydrofolic acid


substrate_name: ATP


organism: Gallus gallus


organism: Ovis aries


organism: Rattus norvegicus


organism: Saccharomyces cerevisiae


organism: Synechocystis sp. PCC 6803


substrate_name: L-aspartic acid


organism: Sus scrofa

substrate_name: dihydroaminopterin


substrate_name: pteroylmonoglutamate


organism: Arabidopsis thaliana

mutation_signature: truncated recombinant enzyme


substrate_name: L-tyrosine


substrate_name: Glu


enzyme_display_name: staphyloferrin B synthase

organism: Staphylococcus aureus


organism: Corynebacterium sp.

substrate_name: Tetrahydropteroyl-L-glutamate; n-1 n-1 n-1 L-Glutamate; n-1 n-1 n-1 ATP


substrate_name: methotrexate-Glu


organism: Escherichia coli

substrate_name: Unknown


substrate_name: methotrexate


organism: Pantoea agglomerans


enzyme_display_name: oxalate--CoA ligase

substrate_name: oxalate


enzyme_display_name: lanosterol synthase


organism: Lacticaseibacillus casei


enzyme_display_name: arginine--tRNA ligase

substrate_name: Arg


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


enzyme_display_name: phosphoribosylanthranilate isomerase


enzyme_display_name: inositol-3-phosphate synthase


enzyme_display_name: serine--tRNA ligase

substrate_name: L-seryl-tRNASer


enzyme_display_name: leucine--tRNA ligase


substrate_name: D-glucose 6-phosphate


enzyme_display_name: methionine--tRNA ligase

substrate_name: Met


enzyme_display_name: mannose-6-phosphate isomerase

substrate_name: mannose 6-phosphate


enzyme_display_name: DNA 5'-3' helicase

substrate_name: ATP


enzyme_display_name: adenylate cyclase


substrate_name: dATP


enzyme_display_name: tyrosine--tRNA ligase

substrate_name: tRNACUA


enzyme_display_name: cellobiose epimerase

organism: Saccharophagus degradans

substrate_name: lactose


enzyme_display_name: methylmalonyl-CoA mutase

organism: Saccharopolyspora erythraea


enzyme_display_name: 3-(methylthio)propionate--CoA ligase

organism: Sagittula stellata


enzyme_display_name: dTDP-4-dehydrorhamnose 3,5-epimerase

organism: Salmonella enterica


enzyme_display_name: glutamine synthetase

organism: Salmonella enterica subsp. enterica serovar Typhimurium


enzyme_display_name: acetate--CoA ligase

substrate_name: acetate


enzyme_display_name: alanine racemase

organism: Salmonella enteritidis PT4 P125109

substrate_name: D-alanine


substrate_name: D-Ala


enzyme_display_name: D-cysteine desulfhydrase

substrate_name: D-cysteine


enzyme_display_name: triose-phosphate isomerase

organism: Schistosoma japonicum

substrate_name: D-glyceraldehyde 3-phosphate


enzyme_display_name: cysteine-S-conjugate beta-lyase

substrate_name: cystathionine


enzyme_display_name: chorismate mutase

organism: Selaginella moellendorffii

substrate_name: chorismate


organism: Shigella dysenteriae


organism: Schizosaccharomyces pombe


enzyme_display_name: alkylmercury lyase

organism: Serratia marcescens

substrate_name: p-hydroxymercuribenzoate


enzyme_display_name: 4-hydroxyproline epimerase

organism: Sinorhizobium meliloti


organism: Solanum chacoense


enzyme_display_name: serine racemase

organism: Solanum lycopersicum

substrate_name: L-serine


enzyme_display_name: L-3-cyanoalanine synthase

organism: Solanum tuberosum

substrate_name: Sulfide


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: hydantoin racemase

substrate_name: L-benzylhydantoin


substrate_name: Chorismate


enzyme_display_name: holocytochrome-c synthase

organism: Saccharomyces cerevisiae

substrate_name: Unknown


enzyme_display_name: ribose-5-phosphate isomerase

organism: Spinacia oleracea

substrate_name: D-ribose 5-phosphate


organism: Sorghum sp.


enzyme_display_name: phosphomannomutase

organism: Sphingomonas sanxanigenens

substrate_name: alpha-D-mannose 1-phosphate


enzyme_display_name: ribulose-phosphate 3-epimerase


substrate_name: D-ribulose 5-phosphate


substrate_name: S-adenosyl-L-methionine


enzyme_display_name: glutamate racemase

organism: Staphylococcus aureus

substrate_name: D-glutamate


enzyme_display_name: methionine--tRNA ligase


enzyme_display_name: adenylate cyclase

organism: Spodoptera frugiperda

substrate_name: ATP


substrate_name: D-alanine


enzyme_display_name: isoleucine--tRNA ligase

substrate_name: tRNAIle


substrate_name: alpha-D-Glucose 1-phosphate


organism: Staphylococcus haemolyticus

substrate_name: L-cystathionine


enzyme_display_name: UDP-N-acetylmuramate--L-alanine ligase


organism: Streptococcus mutans


enzyme_display_name: alanine--tRNA ligase

organism: Streptococcus pneumoniae

substrate_name: lipid II L-Ser


enzyme_display_name: asparagine--tRNA ligase

substrate_name: tRNAAsn


enzyme_display_name: o-succinylbenzoate--CoA ligase


enzyme_display_name: acetate--CoA ligase

substrate_name: acetate


enzyme_display_name: alanine racemase


organism: Streptococcus pyogenes


enzyme_display_name: UDP-glucose 4-epimerase

substrate_name: UDPgalactose


enzyme_display_name: nephthenol synthase

organism: Streptomyces sp.

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: xylose isomerase

organism: Streptomyces corchorusii

substrate_name: D-glucose


organism: Streptococcus iniae


enzyme_display_name: chorismate mutase

organism: Streptomyces venezuelae

substrate_name: chorismate


enzyme_display_name: N-acylglucosamine 2-epimerase

organism: Sus scrofa

substrate_name: N-acetyl-D-mannosamine


enzyme_display_name: selenocysteine lyase

substrate_name: L-selenocysteine


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: inositol-3-phosphate synthase

substrate_name: glucose 6-phosphate


organism: Streptomyces violaceoruber

substrate_name: D-xylose


enzyme_display_name: succinate--CoA ligase (GDP-forming)

substrate_name: succinate


enzyme_display_name: tubulin--tyrosine ligase

substrate_name: L-Dopa


enzyme_display_name: tetrahydrofolate synthase

substrate_name: ATP


enzyme_display_name: microtubule-severing ATPase

organism: Strongylocentrotus purpuratus


enzyme_display_name: thromboxane-A synthase


substrate_name: L-Phe


substrate_name: Unknown


enzyme_display_name: mannose-6-phosphate isomerase

substrate_name: mannose 6-phosphate


enzyme_display_name: cellobiose epimerase

organism: Teredinibacter turnerae

substrate_name: cellobiose


enzyme_display_name: phosphoacetylglucosamine mutase

substrate_name: N-acetylglucosamine 1-phosphate


substrate_name: glucose 1-phosphate


enzyme_display_name: glutamate--tRNA ligase

organism: Tetradesmus obliquus

substrate_name: Glu


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


enzyme_display_name: guanylate cyclase

organism: Tetrahymena pyriformis

substrate_name: GTP


substrate_name: lactose


enzyme_display_name: methionine racemase

organism: Thermococcus litoralis

substrate_name: L-methionine


enzyme_display_name: arginine--tRNA ligase

organism: Thermus thermophilus

substrate_name: tRNAArg


enzyme_display_name: chaperonin ATPase

organism: Thermoplasma acidophilum


enzyme_display_name: alanine--tRNA ligase

substrate_name: tmRNA


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: aspartate--tRNA ligase

substrate_name: tRNAAsn


enzyme_display_name: maltose alpha-D-glucosyltransferase

substrate_name: maltose


enzyme_display_name: threonine--tRNA ligase

substrate_name: tRNAThr


enzyme_display_name: glycine--tRNA ligase

substrate_name: tRNAGly


enzyme_display_name: isoleucine--tRNA ligase

substrate_name: tRNAIle


enzyme_display_name: methionine gamma-lyase

organism: Treponema denticola


substrate_name: Asp


substrate_name: L-cysteine


enzyme_display_name: glutamate racemase

substrate_name: D-glutamate


enzyme_display_name: triose-phosphate isomerase

organism: Trichomonas vaginalis

substrate_name: D-glyceraldehyde 3-phosphate


organism: Trichormus variabilis ATCC 29413

substrate_name: L-Arg


enzyme_display_name: glutamine synthetase

organism: Triticum aestivum

substrate_name: ATP


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


organism: Trichormus variabilis

substrate_name: Glu


organism: Trypanosoma brucei

substrate_name: Variant-surface-glycoprotein


enzyme_display_name: long-chain-fatty-acid--CoA ligase

substrate_name: tetradecanoate


enzyme_display_name: UniProt Q9NRF8

organism: Homo sapiens

substrate_name: L-Gln


substrate_name: UTP


enzyme_display_name: UniProt P0A7D4

organism: Escherichia coli

substrate_name: hydroxylamine


enzyme_display_name: lysine--tRNA ligase

substrate_name: Unknown


enzyme_display_name: serine--tRNA ligase

substrate_name: tRNASecUCA


organism: Trypanosoma brucei brucei


organism: Oryctolagus cuniculus

substrate_name: 5-phosphoribosyl diphosphate


substrate_name: imidazoleacetate


enzyme_display_name: adenylate cyclase

organism: Trypanosoma cruzi


enzyme_display_name: ribose-5-phosphate--ammonia ligase

organism: Gallus gallus


enzyme_display_name: adenylosuccinate synthase

organism: Rattus norvegicus

substrate_name: Asp


substrate_name: GTP


substrate_name: IMP


enzyme_display_name: urea carboxylase

organism: Oleomonas sagaranensis

substrate_name: ATP; Urea; Hydrogencarbonate


substrate_name: L-aspartate


substrate_name: aspartate


substrate_name: alpha-D-glucose 6-phosphate


enzyme_display_name: CTP synthase (glutamine hydrolyzing)


substrate_name: glutamine


substrate_name: ATP


substrate_name: L-glutamine


organism: Kluyveromyces lactis

substrate_name: Urea


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


substrate_name: UTP


substrate_name: XTP


substrate_name: ITP


organism: Plasmodium falciparum


substrate_name: L-Asp


substrate_name: Gln


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: L-glutamine (at unsaturating levels of ATP and UTP (0.5 mM))


enzyme_display_name: formate--tetrahydrofolate ligase

organism: Clostridium cylindrosporum

substrate_name: ADP


substrate_name: tetrahydrofolate


substrate_name: formate


substrate_name: GTP


substrate_name: IMP


substrate_name: Asp


organism: Dictyostelium discoideum


substrate_name: guanosine 5'-tetraphosphate


substrate_name: 6-thioguanosine 5'-triphosphate


substrate_name: glutamine


substrate_name: ATP


enzyme_display_name: argininosuccinate synthase

organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)

substrate_name: citrulline (at 38 degrees Celsius and pH 9.0)


substrate_name: aspartate (at 38 degrees Celsius and pH 9.0)


substrate_name: ATP (at 38 degrees Celsius and pH 9.0)


organism: Leishmania major

substrate_name: Formate; ATP; 5,6,7,8-Tetrahydrofolate


organism: Methylobacterium extorquens


organism: Mus musculus


organism: Schizosaccharomyces pombe

substrate_name: GTP; IMP; L-Aspartate


organism: Zea mays

substrate_name: GTP; L-Aspartate; IMP


organism: Bos taurus

substrate_name: L-Citrulline; ATP; L-Aspartate


organism: Homo sapiens

substrate_name: L-Aspartate; ATP; L-Citrulline


organism: Escherichia coli

substrate_name: Unknown


substrate_name: allopurinol ribonucleotide


substrate_name: IMP; GTP; L-Aspartate


substrate_name: Gln-OH


substrate_name: NH3; UTP; ATP


substrate_name: One carbon pool; 5,6,7,8-Tetrahydrofolate


substrate_name: ADP


substrate_name: tetrahydrofolate


organism: Toxoplasma gondii

substrate_name: UTP


organism: Methanocaldococcus jannaschii


organism: Saccharolobus solfataricus


organism: Kluyveromyces lactis

substrate_name: Urea


organism: Lactococcus lactis subsp. cremoris

substrate_name: UTP; H2O; ATP; L-Glutamine


organism: Lactococcus lactis subsp. lactis

substrate_name: H2O; L-Glutamine; ATP; UTP


organism: Mycobacterium tuberculosis


organism: Saccharomyces cerevisiae

substrate_name: H2O; UTP; L-Glutamine; ATP


organism: Clostridium cylindrosporum


substrate_name: THF monoglutamate


organism: Lactococcus lactis

substrate_name: L-Glutamine


substrate_name: L-Asp


substrate_name: GTP


substrate_name: L-Aspartate


substrate_name: L-aspartate


substrate_name: ATP


substrate_name: formate


substrate_name: IMP


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: L-glutamine


organism: Azotobacter vinelandii


substrate_name: Asp


organism: Ovis aries


substrate_name: tetrahydrofolate


organism: Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)


organism: Schizosaccharomyces pombe


substrate_name: L-citrulline


organism: Zea mays


organism: Plasmodium falciparum


organism: Lactococcus lactis subsp. cremoris (strain MG1363)


substrate_name: ammonia


organism: Escherichia coli


organism: Leishmania major


substrate_name: Formate


organism: Toxoplasma gondii


organism: Dictyostelium discoideum


organism: Homo sapiens

substrate_name: citrulline (at pH 7.0 and 37 degrees Celsius)


substrate_name: aspartate (at pH 7.0 and 37 degrees Celsius)


organism: Oleomonas sagaranensis

substrate_name: Formamide


substrate_name: acetamide


substrate_name: Urea


substrate_name: Carbamoyl phosphate


organism: Lactococcus lactis subsp. lactis

substrate_name: GTP


substrate_name: Unknown


organism: Clostridium cylindrosporum

substrate_name: phosphate


substrate_name: L-Gln


substrate_name: UTP


substrate_name: ATP


substrate_name: citrulline


substrate_name: Asp


organism: Cyberlindnera jadinii


organism: Neomoorella thermoacetica


substrate_name: formate


organism: Clostridium perfringens


organism: Gallus gallus


substrate_name: IMP


organism: Helicobacter pylori


substrate_name: L-aspartate


organism: Rattus norvegicus

substrate_name: diphosphate


substrate_name: AMP


substrate_name: argininosuccinate


organism: Lactococcus lactis


organism: Lathyrus oleraceus


substrate_name: tetrahydrofolate


organism: Trypanosoma brucei