organism: Escherichia coli

substrate_name: ceftazidime


enzyme_display_name: beta-lactamase

substrate_name: nitrocefin

source_db: brenda

ki_display: Not reported

kcat_over_km_display: Not reported

mutation_signature: Unknown

protein_accession_database: UniProt

source_license: CC BY 4.0; CC BY-NC-ND 4.0

km_unit: mM


organism: Pseudomonas aeruginosa

substrate_name: penicillin G

source_db: skid

kcat_display: Not reported

source_license: CC BY-NC-ND 4.0


organism: Serratia marcescens


organism: Psychrobacter immobilis

substrate_name: ampicillin

source_license: CC BY 4.0


enzyme_display_name: caffeine synthase

organism: Coffea arabica

substrate_name: Theobromine


organism: Theobroma cacao


substrate_name: S-adenosyl-L-methionine


organism: Paullinia cupana


source_db: uniprot


organism: Camellia sinensis var. assamica

substrate_name: 1,3,7-trimethyluric acid


enzyme_display_name: carbonic anhydrase

organism: Candida albicans


organism: Homo sapiens


km_display: Not reported


organism: Methanosarcina thermophila


organism: Oncorhynchus mykiss

substrate_name: 4-nitrophenyl acetate


enzyme_display_name: 5-aminolevulinate synthase

organism: Unknown

substrate_name: succinyl-CoA


substrate_name: glycine


organism: Gallus gallus


organism: Mus musculus


substrate_name: butanoyl-CoA


organism: Caulobacter vibrioides


organism: Cereibacter sphaeroides


substrate_name: Unknown

ki_unit: mM


organism: Escherichia coli


organism: Rhodopseudomonas palustris

substrate_name: butyryl-CoA


organism: Saccharomyces cerevisiae


organism: Serratia plymuthica


organism: Paracoccus denitrificans


organism: Plasmodium falciparum


organism: Rattus norvegicus


organism: Rhodobacter capsulatus


enzyme_display_name: protein farnesyltransferase

substrate_name: farnesyl diphosphate


organism: Aspergillus fumigatus

substrate_name: (2E,6E)-farnesyl diphosphate


substrate_name: Thr-Lys-Cys-Val-Ile-Met


organism: Homo sapiens

substrate_name: HOM-GPP


substrate_name: dansyl-GCVKS


substrate_name: dansyl-GCVDS


substrate_name: YRASNRSCAIM


substrate_name: dansyl-GCQL


enzyme_display_name: glycogen phosphorylase

organism: Dictyostelium discoideum

substrate_name: phosphate


organism: Locusta migratoria

substrate_name: glycogen


organism: Solanum tuberosum

substrate_name: alpha-D-Glucan


organism: Typha latifolia

substrate_name: maltoheptaose


organism: Ipomoea batatas


organism: Lathyrus oleraceus


organism: Lethenteron camtschaticum

substrate_name: AMP


organism: Manduca sexta


organism: Mizuhopecten yessoensis

substrate_name: alpha-D-glucose 1-phosphate


organism: Musa x paradisiaca

substrate_name: glucose 1-phosphate


organism: Oryctolagus cuniculus


organism: Oryza sativa

substrate_name: amylopectin


organism: Papiliotrema laurentii


organism: Pyrococcus furiosus

substrate_name: maltotriose


organism: Rattus norvegicus

substrate_name: Unknown


enzyme_display_name: Glycogen phosphorylase

organism: Aquifex aeolicus

substrate_name: maltotetraose


enzyme_display_name: Alpha-1,4 glucan phosphorylase

organism: Chlamydomonas reinhardtii


organism: Corynebacterium callunae

substrate_name: maltopentaose


enzyme_display_name: Glycogen phosphorylase, liver form

organism: Homo sapiens


enzyme_display_name: Glycogen phosphorylase, muscle form


enzyme_display_name: Alpha-glucan phosphorylase, H isozyme

organism: Triticum aestivum


organism: Sulfurisphaera tokodaii str. 7


substrate_name: starch


organism: Sus scrofa


organism: Thermus thermophilus


organism: Voandzeia subterranea


organism: Zea mays


organism: Saccharolobus solfataricus


organism: Saccharomyces cerevisiae


organism: Solanum tuberosum


organism: Spinacia oleracea


organism: Streptococcus salivarius

substrate_name: KF


organism: Acetivibrio thermocellus

substrate_name: dextrin DP19


organism: Agrobacterium tumefaciens


organism: Badhamia polycephala


organism: Chlorella vulgaris

substrate_name: maltodecaheptaose


organism: Clostridium pasteurianum


organism: Corynebacterium callunae


substrate_name: dextrin DP11


organism: Cuscuta reflexa


enzyme_display_name: ornithine carbamoyltransferase

substrate_name: L-ornithine


organism: Squalus acanthias


organism: Sus scrofa


organism: Enterococcus faecalis


organism: Escherichia coli

substrate_name: L-ornithine, Carbamoyl phosphate


substrate_name: Carbamoyl phosphate, L-ornithine


organism: Lathyrus oleraceus


organism: Moritella abyssi


organism: Mycobacterium tuberculosis variant bovis

substrate_name: Carbamoyl phosphate


organism: Ovis aries


organism: Piaractus mesopotamicus


organism: Pseudomonas aeruginosa

substrate_name: ornithine


organism: Pseudomonas savastanoi

substrate_name: Diaminobutane


organism: Pyrococcus furiosus


organism: Rattus norvegicus


enzyme_display_name: Ornithine carbamoyltransferase

enzyme_name_source: UniProtKB:P05150 targeted protein-name/EC/organism lookup

organism: Saccharomyces cerevisiae


organism: Homo sapiens


organism: Pyrococcus abyssi


organism: Thermus thermophilus


organism: Alnus glutinosa


organism: Bacillus subtilis


organism: Chlorella vulgaris var. autotrophica


organism: Escherichia coli


organism: Giardia duodenalis

substrate_name: L-citrulline


organism: Methanosarcina thermophila


enzyme_display_name: cholinesterase

substrate_name: Benzoylcholine


substrate_name: butyrylthiocholine


substrate_name: succinylthiocholine


enzyme_display_name: GDP-fucose protein O-fucosyltransferase 1

enzyme_name_source: UniProtKB P83337

organism: Cricetulus griseus

substrate_name: factor VII EGF


organism: Amblyomma americanum

substrate_name: butanoylthiocholine


organism: Berryteuthis magister

substrate_name: propionylthiocholine


organism: Chelidonichthys lucerna


organism: Diopatra neapolitana


organism: Eisenia andrei

substrate_name: propionylthiocholine iodide


organism: Equus caballus


organism: Gallotia galloti

substrate_name: butyrylthiocholine iodide


organism: Gambusia yucatana


organism: Homo sapiens


organism: Bos taurus

substrate_name: Unknown


substrate_name: Butyrylthiocholine

source_db: oed

verification_status: unverified

kcat_over_km_origin: calculated


substrate_name: (-)-cocaine


substrate_name: benzoylthiocholine


substrate_name: acetylthiocholine


substrate_name: cocaine


substrate_name: Acetylcholine


substrate_name: butyryl thiocholine iodide


substrate_name: N-methylindoxyl acetate


substrate_name: Benzoylcholine


organism: Lumbriculus variegatus

substrate_name: butyrylthiocholine


organism: Mus musculus


organism: Oncorhynchus gorbuscha


organism: Oncorhynchus keta


organism: Oncorhynchus kisutch


organism: Oncorhynchus nerka


organism: Oreochromis niloticus


organism: Oryctolagus cuniculus


organism: Oryza sativa


organism: Potamopyrgus antipodarum


substrate_name: heroin

verification_status: corrected


substrate_name: Acetylthiocholine


organism: Sus scrofa


enzyme_display_name: peptide-O-fucosyltransferase

organism: Arabidopsis thaliana

substrate_name: GDP-beta-L-fucose


organism: Cricetulus griseus


substrate_name: F7 EGF domain


substrate_name: GDP-fucose


substrate_name: Thr-216 of MMRN1 protein


substrate_name: butyrylthiocholine (at 25 degrees Celsius)


organism: Pseudomonas aeruginosa

substrate_name: propionylthiocholine


organism: Pseudopleuronectes yokohamae


organism: Rattus norvegicus


organism: Salmo salar


organism: Sardina pilchardus

substrate_name: butanoylthiocholine


organism: Scomber scombrus


organism: Sparus aurata


organism: Trichinella spiralis

substrate_name: acetylcholine iodide


organism: Valvata piscinalis


organism: Vigna radiata var. radiata


substrate_name: factor VII EGF


organism: Homo sapiens


enzyme_display_name: GDP-fucose protein O-fucosyltransferase 3

substrate_name: GDP-L-fucose


enzyme_display_name: GDP-fucose protein O-fucosyltransferase 2


enzyme_display_name: GDP-fucose protein O-fucosyltransferase 4


enzyme_display_name: sucrose alpha-glucosidase

organism: Bacillus subtilis

substrate_name: p-nitrophenyl-alpha-D-glucoside


organism: Gallus gallus

substrate_name: sucrose


substrate_name: maltose


organism: Mus musculus


organism: Oryctolagus cuniculus


organism: Pyrococcus furiosus

substrate_name: panose


organism: Xanthomonas axonopodis


organism: Perna viridis


organism: Platyrrhini


organism: Rattus rattus


organism: Saccharomyces cerevisiae


organism: Streptococcus salivarius


organism: Sus scrofa

substrate_name: Unknown


organism: Xanthomonas campestris pv. campestris


enzyme_display_name: undecaprenyl-diphosphate phosphatase

organism: Escherichia coli (strain K12)

substrate_name: undecaprenyl pyrophosphate


organism: Escherichia coli

substrate_name: undecaprenyl diphosphate


organism: Micrococcus luteus


substrate_name: farnesyl diphosphate


organism: Vibrio vulnificus


enzyme_display_name: beta-lactamase

substrate_name: cefalotin


substrate_name: ceftazidime


organism: Klebsiella pneumoniae

substrate_name: ticarcillin


organism: Pseudomonas aeruginosa

substrate_name: cefepime


substrate_name: Imipenem


substrate_name: meropenem


organism: Pseudomonas putida


organism: Bacteroides fragilis


organism: Enterobacter cloacae


substrate_name: aztreonam


organism: Serratia marcescens

substrate_name: nitrocefin


organism: Shewanella algae

substrate_name: Cloxacillin


organism: Shewanella frigidimarina

substrate_name: cefaloridine


organism: Shewanella livingstonensis

substrate_name: piperacillin


organism: Psychrobacter immobilis

substrate_name: benzylpenicillin


substrate_name: cefoxitin


organism: Mycobacterium tuberculosis


organism: Burkholderia pseudomallei


organism: Citrobacter freundii

substrate_name: cefazolin


organism: Elizabethkingia meningoseptica

substrate_name: cefotaxime


organism: Escherichia coli

substrate_name: ampicillin


substrate_name: penicillin G


organism: Fluoribacter gormanii

substrate_name: Unknown


organism: plasmid pBG66


substrate_name: cephalexin


organism: plasmid pGEM-T-easy


substrate_name: cephalothin


organism: plasmid pQE32Chl17


organism: plasmid RGN238

substrate_name: cephaloridine


organism: Proteus penneri


organism: [Haemophilus] ducreyi


organism: Janthinobacterium lividum


organism: Klebsiella aerogenes


organism: Klebsiella pneumoniae


organism: Kluyvera ascorbata


organism: Moraxella catarrhalis

substrate_name: Loracarbef


organism: Morganella morganii


organism: Mycobacterium tuberculosis


organism: plasmid pBC


substrate_name: Imipenem


organism: Streptomyces cacaoi


organism: Streptomyces sp.


organism: synthetic construct


organism: Yersinia enterocolitica

substrate_name: cefalotin


organism: Providencia stuartii


organism: Pseudomonas aeruginosa


organism: Psychrobacter immobilis


organism: Serratia fonticola

substrate_name: ceftazidime


organism: Serratia marcescens


organism: Staphylococcus aureus

substrate_name: cefamandole


organism: Stenotrophomonas maltophilia

substrate_name: cefprozil


organism: Streptomyces albus

substrate_name: carbenicillin


organism: Acinetobacter sp.


organism: Aeromonas sobria


organism: Aeromonas veronii


organism: Bacillus anthracis


organism: Bacillus cereus

substrate_name: cephalosporin C


organism: Bacillus licheniformis

substrate_name: nitrocefin


substrate_name: phenoxymethylpenicillin


organism: Bacillus sp. (in: firmicutes)


organism: Bacteroides fragilis


organism: Burkholderia pseudomallei


enzyme_display_name: carbonic anhydrase

organism: Bos taurus

substrate_name: COS


organism: Elephas trogontherii

substrate_name: p-nitrophenyl acetate


organism: Homo sapiens


organism: Mus musculus


organism: Solanum tuberosum


organism: Stylophora pistillata


organism: Unknown


organism: Pseudoalteromonas haloplanktis ANT/505


organism: Sordaria macrospora


organism: Sulfurihydrogenibium azorense


organism: Sulfurihydrogenibium sp. YO3AOP1


organism: Synechocystis sp. PCC 6803 / Kazusa


mutation_signature: recombinant truncated CcaA220 enzyme / CO2 hydration reaction recombinant truncated CcaA220 enzyme


organism: Thermovibrio ammonificans


organism: Trichomonas vaginalis


organism: Mesorhizobium loti

substrate_name: CO2, H2CO3


organism: Methanosarcina thermophila


organism: Methanothermobacter thermautotrophicus


substrate_name: Unknown


organism: Mycobacterium tuberculosis


organism: Mytilus galloprovincialis


organism: Oncorhynchus mykiss


organism: Persephonella marina

substrate_name: CO2; H2CO3


organism: Plasmodium falciparum

mutation_signature: truncated form PfCA1 / truncated form PfCA1


mutation_signature: truncated mutant PfCA1


organism: Porphyromonas gingivalis


organism: Acipenser gueldenstaedtii


organism: Aedes aegypti


organism: Anguilla anguilla


organism: Arabidopsis thaliana


organism: Astrosclera willeyana


organism: Bacillus subtilis

substrate_name: 4-nitrophenyl acetate


organism: Caenorhabditis elegans


organism: Candida albicans


organism: Cavia porcellus


organism: Chionodraco hamatus


organism: Clostridium perfringens


organism: Coccomyxa sp.


organism: Columba livia


organism: Conticribra weissflogii


organism: Corynebacterium flavescens


organism: Cryptococcus neoformans


organism: Cyprinus carpio


organism: Drosophila melanogaster


organism: Dunaliella salina


organism: Entamoeba histolytica


organism: Felis catus


organism: Flaveria bidentis


organism: Gyrodactylus salaris


organism: Halomonas sp.


organism: Halothiobacillus neapolitanus


organism: Helicobacter pylori


organism: Homo sapiens


organism: Lacticaseibacillus rhamnosus


organism: Lathyrus oleraceus


organism: Leishmania chagasi


organism: Macropus eugenii desmarest


organism: Malassezia globosa


organism: Malassezia pachydermatis


organism: Malassezia restricta


organism: Methanosarcina thermophila


organism: Brucella suis


organism: Colwellia psychrerythraea


organism: Conticribra weissflogii


organism: Danio rerio


organism: Dunaliella salina


organism: Enterobacter sp. B13


organism: Escherichia coli


organism: Helicobacter pylori


organism: Homo sapiens


organism: Nostoc commune


organism: Nostoc sp.


organism: Oncorhynchus mykiss


organism: Oryctolagus cuniculus


organism: Oryza sativa


organism: Ovis aries


organism: Petromyzon marinus


organism: Petroselinum crispum


organism: Plasmodium falciparum


organism: Populus tremula


organism: Porphyromonas gingivalis


organism: Python bivittatus


organism: Rattus norvegicus


organism: Rhodospirillum rubrum


organism: Saccharomyces cerevisiae


organism: Salmo labrax


organism: Salmo trutta Labrax Coruhensis


organism: Sander vitreus


organism: Struthio camelus


organism: Sulfurihydrogenibium azorense


organism: Sulfurihydrogenibium yellowstonense


organism: Sus scrofa


organism: Tectona grandis


organism: Thalassiosira pseudonana


organism: Methanosarcina thermophila


organism: Methanothermobacter thermautotrophicus


organism: Micropterus salmoides


organism: Mus musculus


organism: Trachurus trachurus


organism: Trematomus bernacchii


organism: Trypanosoma cruzi


organism: Vibrio cholerae serotype O1


mutation_signature: truncated form of carbonic anhydrase VII lacking the amino-terminal 23 residues of recombinant enzyme truncated form of carbonic anhydrase VII lacking the amino


organism: Mycobacterium tuberculosis


organism: Nakaseomyces glabratus

substrate_name: histamine


organism: Neisseria gonorrhoeae


organism: Homo sapiens


organism: Cryptococcus neoformans


organism: Saccharomyces cerevisiae


organism: Brucella suis


organism: Mesorhizobium loti


organism: Persephonella marina


organism: Plasmodium falciparum


enzyme_display_name: tyrosinase

organism: Priestia megaterium

substrate_name: L-Dopa


substrate_name: L-tyrosine


organism: Charybdis japonica


organism: Solanum tuberosum


enzyme_display_name: versatile peroxidase

organism: Pleurotus eryngii

substrate_name: syringol


organism: Pleurotus ostreatus


substrate_name: Reactive Black 5


organism: Pseudomonas putida

substrate_name: Acid Blue 62


organism: Stereum ostrea

substrate_name: Phenol red


organism: Pleurotus sapidus

substrate_name: beta-carotene


organism: Rhodococcus jostii


substrate_name: catechol


organism: Bjerkandera adusta

substrate_name: veratryl alcohol


substrate_name: Reactive Violet 5


organism: Bjerkandera fumosa


organism: Bjerkandera sp.


enzyme_display_name: coagulation factor Xa

organism: Unknown


organism: Rattus norvegicus


organism: Bos taurus


organism: Camelus bactrianus


organism: Canis lupus familiaris


organism: Homo sapiens


substrate_name: prothrombin


organism: Mammalia


organism: Mus musculus


organism: Oryctolagus cuniculus


enzyme_display_name: phosphatidylserine decarboxylase

substrate_name: phosphatidylserine


substrate_name: phosphatidyl-L-serine


organism: Tetrahymena pyriformis


organism: Toxoplasma gondii


organism: Plasmodium falciparum

substrate_name: dioleoyl phosphatidylserine


organism: Toxoplasma gondii (strain ATCC 50853 / GT1)


organism: Escherichia coli


substrate_name: Phosphatidylserine

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: Dipalmitoyl phosphatidylserine


substrate_name: Dioleoyl phosphatidylserine


verification_status: verified


organism: Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)

substrate_name: Unknown


organism: Thermus brockianus

substrate_name: maltotriose


organism: Thermus thermophilus


substrate_name: maltotetraose


substrate_name: maltopentaose


organism: Aquifex aeolicus


organism: Corynebacterium glutamicum


organism: Ipomoea batatas


organism: Lathyrus oleraceus


organism: Manihot esculenta


organism: Paenibacillus macerans

substrate_name: dodecyl-beta-maltoside


organism: Pyrobaculum aerophilum


organism: Saccharolobus solfataricus

substrate_name: maltosyl-beta-cyclodextrin


organism: Saccharomyces cerevisiae

substrate_name: phi-dextrin


organism: Stutzerimonas stutzeri


organism: Arabidopsis thaliana


substrate_name: starch


substrate_name: starch; maltotriose


substrate_name: maltoheptaose


substrate_name: Maltotriose


substrate_name: Maltohexaose


substrate_name: Maltotriose; D-Glucose; Maltopentaose; Maltotetraose; Maltotetraose; Maltotetraose; Maltoheptaose; Maltopentaose; Maltopentaose; Malto-oligosaccharide; Maltohexaose


organism: Thermococcus litoralis

source_db: brenda;skid


organism: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)


organism: Homo sapiens

substrate_name: UTP


substrate_name: N-acetyl-D-galactosamine 1-phosphate


substrate_name: UDP-N-acetyl-alpha-D-galactosamine


substrate_name: UDP-N-acetylglucosamine


enzyme_display_name: oryzalexin D synthase

organism: Oryza sativa subsp. japonica

substrate_name: ent-cassadiene


organism: Oryza sativa

substrate_name: H+; NADPH; O2; ent-Sandaracopimaradiene


substrate_name: ent-kaurene


organism: Mus musculus

substrate_name: histone octamer


enzyme_display_name: magnesium protoporphyrin IX methyltransferase

organism: Chlorobaculum tepidum

substrate_name: magnesium protoporphyrin


organism: Hordeum vulgare

substrate_name: magnesium protoporphyrin IX


organism: Synechocystis sp.

substrate_name: S-adenosyl-L-methionine


organism: Triticum aestivum


organism: Rhodobacter capsulatus


substrate_name: S-Adenosyl-L-methionine


substrate_name: [histone H3]-L-lysine36


substrate_name: recombinant nucleosome


enzyme_display_name: formimidoylglutamase

organism: Bacillus subtilis (strain 168)

substrate_name: Unknown


organism: Trypanosoma cruzi

substrate_name: N-formimidoyl-L-glutamate


enzyme_display_name: 5-deoxyribulose 1-phosphate aldolase

organism: Bacillus thuringiensis serovar kurstaki

substrate_name: 5-deoxy-D-ribulose 1-phosphate


organism: Sulfurisphaera tokodaii

substrate_name: alpha-D-galactosamine 1-phosphate


mutation_signature: DC005 with a deletion of the C-terminal 5 residues of the ST0452 protein


mutation_signature: DC011 with a deletion of the C-terminal 11 residues of the ST0452 protein


substrate_name: N-Acetylglucosamine 6-sulfate; H2O


enzyme_display_name: DNA primase AEP

substrate_name: ATP


organism: Pyrococcus abyssi

substrate_name: dNTP


organism: Saccharolobus solfataricus

substrate_name: NTP


organism: Sulfolobus islandicus


substrate_name: dATP


enzyme_display_name: deoxyribodipyrimidine photo-lyase

organism: Escherichia coli

substrate_name: cis-syn Cyclobutadipyrimidine


organism: Homo sapiens

substrate_name: dTTP (in presence of 2 mM of Mn(2+))


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: dNTPs


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


organism: Escherichia coli O45:K1 (strain S88 / ExPEC)


organism: Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)


enzyme_display_name: abieta-7,13-dien-18-ol hydroxylase

organism: Abies grandis

substrate_name: abietadienol


organism: Pinus taeda

substrate_name: isopimaradienol


organism: Bos taurus

substrate_name: N-acetyl-D-glucosamine 6-sulfate


organism: Capra hircus

substrate_name: 4-Methylumbelliferyl sulfate


substrate_name: glucose 6-sulfate


organism: Bacillus subtilis


organism: Pseudomonas putida


substrate_name: S-methyl-5-thio-D-ribulose 1-phosphate


organism: Rhodospirillum rubrum

substrate_name: ribulose 1-phosphate


substrate_name: pyrimidine dimer in DNA


organism: Vibrio cholerae serotype O1

substrate_name: cyclobutadipyrimidine in DNA


organism: Saccharolobus islandicus


enzyme_display_name: adrenodoxin-NADP(+) reductase

organism: Rattus norvegicus

substrate_name: NADPH


organism: Arabidopsis thaliana

substrate_name: H+; NADPH; Oxidized adrenal ferredoxin


enzyme_display_name: hygromycin-B 7''-O-kinase

organism: Streptomyces hygroscopicus

substrate_name: hygromycin B


substrate_name: ATP


enzyme_display_name: diglucosyl diacylglycerol synthase (1,6-linking)

organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)

substrate_name: UDP-glucose


enzyme_display_name: oleuropein beta-glucosidase

organism: Olea europaea

substrate_name: oleuropein


organism: Mycoplasma genitalium


substrate_name: UDP-alpha-D-glucose


substrate_name: UDP-alpha-D-galactose


organism: Mycoplasmoides genitalium


substrate_name: Oleuropein; H2O


organism: Streptomyces sp.


organism: Prunus dulcis


organism: Saccharolobus solfataricus


organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)

substrate_name: magnesium ion


organism: Bacteroides thetaiotaomicron

substrate_name: N-acetylneuraminic acid 9-phosphate


enzyme_display_name: phenylethanolamine N-methyltransferase

organism: Unknown

substrate_name: Unknown


organism: Bos taurus


organism: Columba livia

substrate_name: S-adenosyl-L-methionine


organism: Homo sapiens

substrate_name: phenylethanolamine


substrate_name: norepinephrine


organism: Oryctolagus cuniculus


organism: Rattus norvegicus


organism: Macaca mulatta

substrate_name: normetanephrine


substrate_name: normetanephrine (enzyme found in the brain)


substrate_name: octopamine


source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


enzyme_display_name: 7-deoxyloganetin glucosyltransferase

organism: Catharanthus roseus


organism: Gardenia jasminoides

substrate_name: genipin


enzyme_display_name: tagatose-6-phosphate kinase


organism: Lactococcus lactis subsp. lactis

substrate_name: ATP; D-Tagatose 6-phosphate


organism: Staphylococcus aureus

substrate_name: ATP


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: fructose 6-phosphate


enzyme_display_name: beta-N-acetylgalactosaminidase

organism: Paenibacillus sp.


organism: Bacillus sp. (in: firmicutes)


organism: Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc)

substrate_name: pNP-GlcNAc (at pH 7.0 and 37 degrees Celsius)


organism: Mycobacterium tuberculosis

substrate_name: NADH


enzyme_display_name: 5-aminolevulinate synthase

substrate_name: succinyl-CoA


substrate_name: glycine


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: succinyl-CoA; glycine


organism: Mus musculus


organism: Rhodobacter capsulatus

substrate_name: glycine; succinyl-CoA


enzyme_display_name: glutamine kinase

organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

substrate_name: L-glutamine (at pH 8.0 and 25 degrees Celsius)


organism: Campylobacter jejuni


substrate_name: L-Glutamine; ATP; H2O

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: D-Glutamine


substrate_name: gamma-L-glutamyl hydrazide


substrate_name: L-glutamine


substrate_name: gamma-L-glutamyl hydroxamate


enzyme_display_name: trimethyltridecatetraene synthase

organism: Zea mays


organism: Arabidopsis thaliana

substrate_name: (6E,10E)-Geranyllinalool; O2; NADPH; H+


substrate_name: H+; NADPH; O2; (6E,10E)-Geranyllinalool


enzyme_display_name: vancomycin aglycone glucosyltransferase

organism: Amycolatopsis orientalis

substrate_name: UDP-alpha-D-glucose


substrate_name: vancomycin aglycone


substrate_name: UDP-glucose


enzyme_display_name: dehydrogluconokinase

organism: Klebsiella aerogenes


organism: Cupriavidus necator

substrate_name: ATP


substrate_name: ATP; 2-Dehydro-D-gluconate


enzyme_display_name: 2-aminobenzoylacetyl-CoA thioesterase

organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: S-ethyl-acetothioacetate


organism: Pseudomonas aeruginosa


substrate_name: acetoacetyl-CoA


enzyme_display_name: L-galactose 1-phosphate phosphatase

substrate_name: D-myoinositol 3-phosphate


organism: Actinidia deliciosa

substrate_name: L-Galactose 1-phosphate; H2O


substrate_name: beta-L-galactose 1-phosphate


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (at pH 7.5 and at 25 degrees Celsius)


organism: Gallus gallus


organism: Treponema denticola


substrate_name: 4-carboxy-5-aminoimidazole ribonucleotide; CO2; 5-aminoimidazole ribonucleotide


organism: Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)

substrate_name: CO(2) (at 10 degrees Celsius)


enzyme_display_name: D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,4-lactone-forming)

organism: Haloarcula marismortui

substrate_name: D-ribose


substrate_name: D-Xylose


substrate_name: D-glucose


substrate_name: D-ribose; D-xylose; D-glucose; NAD+; NADP+


organism: Haloferax volcanii

substrate_name: NAD+; D-xylose; NADP+; D-glucose


organism: Eupatorium cannabinum

substrate_name: NAD+


organism: Senecio vernalis

substrate_name: putrescine


substrate_name: Spermidine


substrate_name: Putrescine; Spermidine


substrate_name: Putrescine


enzyme_display_name: tetrahydrocannabinolic acid synthase

organism: Cannabis sativa

substrate_name: cannabigerolate


substrate_name: cannabigerolic acid


enzyme_display_name: sphingomyelin phosphodiesterase D

organism: Corynebacterium pseudotuberculosis

substrate_name: H2O; 1-Oleoylglycerophosphocholine


organism: Loxosceles intermedia

substrate_name: sphingomyelin


organism: Loxosceles laeta


organism: Rattus norvegicus


enzyme_display_name: protein arginine phosphatase

substrate_name: [culpeine]-Nomega-phospho-L-arginine


organism: Bacillus subtilis (strain 168)

substrate_name: p-nitrophenyl-phosphate (at 37 degrees Celsius and pH 5.5)


organism: Geobacillus stearothermophilus

substrate_name: p-nitrophenyl-phosphate (at 25 degrees Celsius and pH 7.6)


organism: Drosophila melanogaster

substrate_name: phospho-L-arginine


substrate_name: 4-nitrophenyl phosphate


enzyme_display_name: chondroitin 4-sulfotransferase

organism: Homo sapiens

substrate_name: PAPS


mutation_signature: with deletion of C-terminal glycosylation site


substrate_name: 3'-phosphoadenylyl sulfate


organism: Mus musculus

substrate_name: 3'-Phosphoadenylyl sulfate; Chondroitin


enzyme_display_name: CMP-N-acetylneuraminate monooxygenase

organism: Asterias rubens

substrate_name: CMP-N-acetylneuraminate


organism: Sus scrofa


substrate_name: CMP-NeuAc


substrate_name: H+; O2; Ferrocytochrome b5; CMP-N-acetylneuraminate


substrate_name: Ferrocytochrome b5; H+; O2; CMP-N-acetylneuraminate


substrate_name: cytochrome b5


enzyme_display_name: nucleoside-phosphate kinase

substrate_name: dAMP


substrate_name: ATP; AMP


organism: Gallus gallus

substrate_name: ATP


substrate_name: AMP with ATP as phosphate donor


substrate_name: AMP (with ATP as phosphate donor)


substrate_name: ThDP


substrate_name: O-(alpha-L-iduronic acid 2-sulfate)-(1-4)-D-O-(alpha 2-sulfaminoglucosamine 6-sulfate)-(1-4)-L-O-(alpha-L-iduronic acid 2-sulfate)-D-O-2,5-anhydro-mannitol 6-sulfate


substrate_name: O-(alpha-L-Idopyranosyluronic acid 2-sulfate)-(1->4)-2,5-anhydro-D-mannitol 6-sulfate; H2O


substrate_name: sphingomyelin


enzyme_display_name: 2-acylglycerol O-acyltransferase

organism: Arachis hypogaea

substrate_name: oleoyl-CoA


organism: Locusta migratoria


organism: Zonotrichia albicollis

substrate_name: linoleoyl-CoA


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: oleoyl-CoA; 1-oleoyl-sn-glycerol


substrate_name: sn-1-Monooleoylglycerol; Oleoyl-CoA


enzyme_display_name: heparanase

substrate_name: fondaparinux


substrate_name: M09 S05a, a heparin sulfate analog with a nonasaccharide with N-sulfation and a single GlcNS(6S) toward the reducing end


substrate_name: fondaparinux / heparan sulfate disaccharide source labels unresolved


enzyme_display_name: allantoinase

organism: Phaseolus vulgaris

substrate_name: allantoin


organism: Unknown

substrate_name: (S)-allantoin


organism: Cajanus cajan


organism: Escherichia coli


organism: Glycine max

substrate_name: H2O; (S)(+)-Allantoin


organism: Lathyrus sativus


organism: Pseudomonas aeruginosa


organism: Ricinus communis


organism: Salmonella enterica


organism: Vigna radiata


organism: Vigna unguiculata subsp. cylindrica


organism: Arabidopsis thaliana


organism: Escherichia coli (strain K12)

substrate_name: allantoin (at 40 degrees Celsius and pH 8.0)


organism: Pseudomonas fluorescens


substrate_name: (S)(+)-Allantoin


organism: Bacillus licheniformis


substrate_name: H2O; Allantoin


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Mycobacterium tuberculosis


organism: Mycolicibacterium smegmatis


enzyme_display_name: very-long-chain 3-oxoacyl-CoA synthase

organism: Saccharomyces cerevisiae

substrate_name: lauroyl-CoA


organism: Homo sapiens

substrate_name: alpha-Linolenoyl-CoA; Malonyl-CoA


substrate_name: palmitoyl-CoA


substrate_name: Malonyl-CoA; Octanoyl-CoA


substrate_name: hexadecanoyl-CoA (at 37 degrees Celsius and pH 6.8)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: octanoyl-CoA


enzyme_display_name: inosine kinase

organism: Helianthus tuberosus

substrate_name: Inosine


organism: Limnospira platensis


organism: Mus musculus


substrate_name: guanosine


organism: Exiguobacterium acetylicum


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: ATP (at 70 degrees Celsius)


organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

substrate_name: guanosine (at pH 8.0 and 22 degrees Celsius)


enzyme_display_name: trehalose 2-sulfotransferase

organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: 3'-phosphoadenylyl sulfate


substrate_name: alpha,alpha-trehalose


organism: Escherichia coli

substrate_name: dATP


organism: Rattus norvegicus


substrate_name: Unknown


organism: Arachis hypogaea

substrate_name: oleoyl-CoA


enzyme_display_name: succinyl-CoA:mesaconate CoA transferase

organism: Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)

substrate_name: succinyl-CoA (in the presence of 10 mM mesaconate)


organism: Haloarcula hispanica

substrate_name: mesaconate


substrate_name: succinyl-CoA


enzyme_display_name: FMN hydrolase

organism: Arabidopsis thaliana

substrate_name: FMN


organism: Capra hircus


substrate_name: riboflavin (at pH 7.5)


enzyme_display_name: D-dopachrome decarboxylase

substrate_name: D-dopachrome


enzyme_display_name: cellobiose phosphorylase

organism: Unknown

substrate_name: cellobiose


organism: Acetivibrio thermocellus


organism: Caldicellulosiruptor bescii


organism: Cellulomonas uda

substrate_name: lactose


organism: Thermoclostridium stercorarium


organism: Thermosipho africanus

substrate_name: D-glucose


substrate_name: cellopentaose; D-xylose; cellotriose; D-glucose; cellotetraose; cellobiose; alpha-D-glucose 1-phosphate


substrate_name: cellopentaose


substrate_name: D-Xylose


substrate_name: cellotetraose


substrate_name: cellotriose


substrate_name: alpha-D-glucose 1-phosphate


organism: Thermotoga neapolitana


substrate_name: Phosphate; Cellobiose; Phosphate; Cellobiose; D-Glucose; D-Glucose 1-phosphate


substrate_name: Cellobiose


organism: Cellulomonas gilvus


substrate_name: methyl beta-D-glucoside


organism: Ruminococcus albus


enzyme_display_name: FAD diphosphatase

substrate_name: FAD; H2O


organism: Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)


organism: Chlamydomonas reinhardtii

substrate_name: FMN / FAD (30 degrees Celsius, pH 7.0)


organism: Homo sapiens

substrate_name: multiple FMN/FAD/ATP/NaPPi contexts


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: FAD with magnesium or cobalt ions (30 degrees Celsius, pH 7.0)


substrate_name: FAD


substrate_name: D-mannose


substrate_name: D-glucosamine


organism: Saccharophagus degradans

substrate_name: cellobiose


organism: Thermotoga maritima

substrate_name: D-glucose


organism: unidentified


organism: Rattus norvegicus


enzyme_display_name: ferredoxin--NAD(+) reductase

organism: Bacillus subtilis

substrate_name: NADH; Oxidized ferredoxin


organism: Acidaminococcus fermentans

substrate_name: oxidized [2Fe-2S] ferredoxin


organism: Acinetobacter sp.

substrate_name: NADH


organism: Clostridium acetobutylicum

substrate_name: NAD+; Reduced ferredoxin; H+


organism: Methylosinus trichosporium OB3b


organism: Mycobacterium sp.

substrate_name: oxidized ferredoxin


substrate_name: ferricytochrome c


organism: Pseudomonas putida


organism: Pseudomonas sp.


enzyme_display_name: feruloyl-CoA hydratase/lyase

organism: Pseudomonas fluorescens

substrate_name: feruloyl-CoA


enzyme_display_name: allantoicase

substrate_name: allantoate


organism: Burkholderia cepacia

substrate_name: (-)-Ureidoglycolate; H2O; Allantoate


organism: Chlamydomonas reinhardtii

substrate_name: Allantoate


substrate_name: H2O; Allantoate; Ureidoglycolate


organism: Mus musculus


organism: Xenopus laevis

substrate_name: H2O; Allantoate


organism: Streptomyces viridiviolaceus


enzyme_display_name: 13-deoxydaunorubicin hydroxylase

organism: Streptomyces sp. (strain C5)

substrate_name: daunorubicin (at pH 7.5 and 30 degrees Celsius)


organism: Streptomyces sp.


substrate_name: daunorubicin


organism: Aquifex aeolicus


enzyme_display_name: chlorate reductase

organism: Azospira oryzae

substrate_name: bromate


organism: Haloferax mediterranei

substrate_name: Chlorate


organism: Triticum aestivum

substrate_name: S-Adenosyl-L-methionine; Tricetin


substrate_name: tricetin


enzyme_display_name: (R,S)-reticuline 7-O-methyltransferase

organism: Papaver somniferum

substrate_name: guaiacol


substrate_name: (R)-reticuline


substrate_name: (S)-reticuline


enzyme_display_name: hydroxyethylthiazole kinase

organism: Staphylococcus aureus


enzyme_display_name: alkylglycerone-phosphate synthase

organism: Cavia porcellus


organism: Trypanosoma brucei

substrate_name: Palmitoyldihydroxyacetone phosphate


enzyme_display_name: S-methyl-5-thioribose kinase

organism: Bacillus subtilis

substrate_name: ATP; 5-Methylthio-D-ribose


organism: Oryza sativa


enzyme_display_name: inositol-1,3,4-trisphosphate 5/6-kinase

organism: Arabidopsis thaliana


organism: Bos taurus


organism: Homo sapiens


enzyme_display_name: pyruvate kinase

substrate_name: Phosphoenolpyruvate; ADP


organism: Zea mays

substrate_name: ATP


enzyme_display_name: glucuronokinase

substrate_name: D-glucuronic acid


enzyme_display_name: hydroxylysine kinase

substrate_name: (5R)-5-hydroxy-L-lysine (in the presence of 2 mM ATP)


organism: Unknown


organism: Aquifex aeolicus (strain VF5)


organism: Escherichia coli (strain K12)


organism: Stutzerimonas chloritidismutans

substrate_name: chlorate


substrate_name: palmitoyl-dihydroxyacetonephosphate (in the presence of 0.5 mM of hexadecanol)


organism: Rattus norvegicus

substrate_name: hexadecanol


organism: Glycine max


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) (with methyl viologen as electron donor and at 30 degrees Celsius)


organism: Papaver somniferum


organism: Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73)


organism: Escherichia coli O45:K1 (strain S88 / ExPEC)


substrate_name: thiazole


organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

substrate_name: D-glycero-alpha-D-manno-heptose 1-phosphate (at pH 7.4 and 25 degrees Celsius)


organism: Aquifex aeolicus

substrate_name: Unknown


organism: Burkholderia glumae


organism: Escherichia coli


organism: Azospira oryzae

substrate_name: Chlorate


substrate_name: reduced benzyl viologen


organism: Cavia porcellus


substrate_name: octadecanol


organism: Bacillus subtilis


organism: Klebsiella aerogenes


organism: Klebsiella pneumoniae


organism: Lupinus luteus


organism: Bos taurus


organism: Saccharomyces cerevisiae


organism: Saccharomyces pastorianus


organism: Schistosoma mansoni


organism: Spinacia oleracea


organism: Streptococcus mutans


organism: Streptococcus sanguis


organism: Synechococcus elongatus


organism: Toxoplasma gondii


organism: Trachemys scripta


organism: Trypanosoma brucei


organism: Trypanosoma cruzi


organism: Zapus hudsonius


organism: Danio rerio

substrate_name: D-glucuronate


organism: Lilium longiflorum


organism: Rattus norvegicus

substrate_name: GTP; 5-Hydroxy-L-lysine


enzyme_display_name: beta-lactamase

organism: Serratia fonticola

substrate_name: ceftazidime


organism: Vigna radiata var. radiata

substrate_name: NADH


organism: Homo sapiens


organism: Bos taurus

substrate_name: Phosphoenolpyruvate; ADP


organism: Brassica napus


organism: Canis familiaris


organism: Columba livia


organism: Coprinopsis lagopus


organism: Cupriavidus necator


organism: Mus musculus


organism: Mustela vison


organism: Ricinus communis


organism: Unknown

substrate_name: H2O; Cephalothin


organism: Escherichia coli

substrate_name: H2O; Nitrocefin

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


substrate_name: H2O; Cephaloridine


substrate_name: cefpirome


substrate_name: cefoxitin


substrate_name: nitrocefin


organism: Pseudomonas putida

substrate_name: H2O; Ampicillin


substrate_name: moxalactam


organism: Shewanella livingstonensis

substrate_name: H2O; Amoxicillin


organism: Stenotrophomonas maltophilia


organism: Klebsiella pneumoniae

substrate_name: ceftaxidime


substrate_name: temocillin


organism: Aeromonas sobria

substrate_name: H2O; Imipenem


organism: Enterobacter cloacae


organism: Haemophilus ducreyi


substrate_name: H2O; Benzylpenicillin


organism: Mycobacterium tuberculosis


organism: Proteus vulgaris


organism: Pseudomonas aeruginosa

substrate_name: Cefdinir; H2O


substrate_name: ceftazidime


organism: Pseudomonas fluorescens

substrate_name: carbenicillin


enzyme_display_name: deoxycytidine kinase

organism: Homo sapiens

substrate_name: cytidine


substrate_name: gemcitabine


substrate_name: Zalcitabine


substrate_name: Cytarabine


substrate_name: ATP

mutation_signature: residues 65-79 deletion mutant with 2-deoxycytidine as cosubstrate


mutation_signature: residues 65-79 deletion mutant with 1-beta-D-arabinofuranosylcytosine as cosubstrate


mutation_signature: residues 65-79 deletion mutant with ATP as cosubstrate


mutation_signature: residues 65-79 deletion mutant with UTP as cosubstrate


substrate_name: UTP


substrate_name: Phosphoenolpyruvate; ADP


organism: Saccharomyces cerevisiae


organism: Trichomonas vaginalis


organism: Trypanosoma brucei


organism: Arabidopsis thaliana

substrate_name: ATP; D-Glucuronate


organism: Bacillus subtilis

substrate_name: GTP; 2'-Deoxycytidine


organism: Gallus gallus

substrate_name: deoxycytidine


organism: Unknown

substrate_name: deoxyguanosine


substrate_name: L-thymidine


substrate_name: D-thymidine


substrate_name: 2'-Deoxycytidine; ATP


substrate_name: thymidine


enzyme_display_name: Beta-lactamase

organism: Acinetobacter baumannii

substrate_name: Imipenem


substrate_name: Cefotaxime; H2O


substrate_name: 7-aminocephalosporanic acid


organism: Bacillus subtilis (strain 168)

substrate_name: deoxyadenosine (with GTP at pH 8.5 and at 37 degrees Celsius)


substrate_name: deoxycytidine (dC)


organism: Mus musculus


organism: Bos taurus

substrate_name: cytosine arabinoside


substrate_name: troxacitabine


substrate_name: gemcitabine


organism: Aeromonas hydrophila

substrate_name: benzylpenicillin


substrate_name: biapenem


substrate_name: nitrocefin


substrate_name: H2O; Ampicillin


organism: Aeromonas veronii

substrate_name: Unknown


organism: Aeromonas veronii bv. sobria


organism: Achromobacter sp. sallbros1

substrate_name: piperacillin


organism: Achromobacter xylosoxidans

substrate_name: cephalothin


substrate_name: ampicillin


substrate_name: ticarcillin


substrate_name: Imipenem


organism: Acinetobacter baylyi


organism: Acinetobacter bereziniae


organism: Acinetobacter pittii


organism: Aeromonas enteropelogenes

substrate_name: cefotaxime


substrate_name: H2O; Imipenem


enzyme_display_name: Beta-lactamase OXA-9

organism: Enterobacter aerogenes

substrate_name: H2O; Nitrocefin


organism: Enterobacter cloacae

substrate_name: Cefotaxime; H2O


substrate_name: ceftazidime


substrate_name: 7-aminocephalosporanic acid


enzyme_display_name: Imipenem-hydrolyzing beta-lactamase

substrate_name: Penicillin G; H2O


organism: Escherichia coli

substrate_name: H2O; Cephaloridine


enzyme_display_name: Beta-lactamase Toho-1

substrate_name: Benzylpenicillin; H2O


substrate_name: cefpirome


enzyme_display_name: Beta-lactamase TEM


enzyme_display_name: Beta-lactamase CTX-M-25

substrate_name: H2O; Benzylpenicillin


substrate_name: H2O; Penicillin G


enzyme_display_name: Beta-lactamase OXA-1


substrate_name: cefepime


substrate_name: cefalotin


substrate_name: CENTA; H2O


substrate_name: cephalothin


substrate_name: Imipenem


substrate_name: cefoxitin


substrate_name: nitrocefin


substrate_name: H2O; Cefuroxime


substrate_name: H2O; Ampicillin


organism: Fluoribacter gormanii


organism: Fusobacterium nucleatum

substrate_name: ampicillin


organism: Homo sapiens

substrate_name: H2O; Cefotaxime


substrate_name: H2O; Imipenem


organism: Klebsiella aerogenes

substrate_name: Unknown


substrate_name: benzylpenicillin


organism: Pseudomonas aeruginosa


substrate_name: ertapenem


substrate_name: ceftazidime


substrate_name: cephalotin


substrate_name: H2O; Nitrocefin


substrate_name: H2O; Penicillin G


organism: Pseudomonas fluorescens

substrate_name: carbenicillin


organism: Pseudomonas luteola

substrate_name: ticarcillin


organism: Pseudomonas putida

substrate_name: cefepime


organism: Riemerella anatipestifer


organism: Serratia fonticola

substrate_name: moxalactam


substrate_name: H2O; Benzylpenicillin


organism: Klebsiella oxytoca


organism: Klebsiella pneumoniae


substrate_name: ceftaxidime


substrate_name: aztreonam


substrate_name: cefalothin


substrate_name: temocillin


substrate_name: ampicillin


substrate_name: nitrocefin


substrate_name: piperacillin


substrate_name: cefoperazone


substrate_name: H2O; Imipenem


substrate_name: Nitrocefin; H2O


substrate_name: H2O; Nitrocefin


substrate_name: ATP; 2'-Deoxycytidine


organism: Lactobacillus acidophilus

substrate_name: ATP; Deoxycytidine


organism: Macaca fascicularis


organism: Mus musculus


organism: Mycoplasma mycoides


organism: Rattus norvegicus


organism: Xenopus laevis

substrate_name: deoxyguanosine


substrate_name: ATP; 5-Hydroxy-L-lysine


organism: Burkholderia pseudomallei

substrate_name: D-glucose 1-phosphate


substrate_name: GTP


organism: Yersinia pseudotuberculosis


substrate_name: alpha-D-mannose 1-phosphate


organism: Mycolicibacterium smegmatis

substrate_name: Bocillin-FL


organism: Nocardia asteroides

substrate_name: H2O; Penicillin G


organism: Nocardia farcinica


organism: Ochrobactrum anthropi


organism: Pectobacterium carotovorum

substrate_name: cefoxitin


organism: Proteus mirabilis


organism: Providencia stuartii


organism: Pseudomonas aeruginosa

substrate_name: carbenicillin


substrate_name: cephalotin


substrate_name: cefotaxime


organism: Klebsiella pneumoniae


substrate_name: Imipenem


organism: Klebsiella pneumoniae subsp. ozaenae


organism: Kluyvera ascorbata


organism: Laribacter hongkongensis

substrate_name: cephalothin


organism: Metapseudomonas otitidis


organism: Moraxella catarrhalis

substrate_name: Amoxicillin; H2O


organism: Morganella morganii

substrate_name: H2O; Ampicillin


substrate_name: Benzylpenicillin; H2O


organism: Morganella morganii subsp. morganii


substrate_name: piperacillin


organism: Mycobacterium tuberculosis

substrate_name: H2O; Nitrocefin


organism: Serratia marcescens

substrate_name: nitrocefin


substrate_name: benzylpenicillin


substrate_name: H2O; Cephaloridine


organism: Shewanella algae


organism: Shewanella frigidimarina

substrate_name: H2O; Amoxicillin


organism: Shewanella livingstonensis


organism: Shigella sonnei


organism: Shouchella clausii

substrate_name: ceftazidime


organism: Shouchella lehensis

substrate_name: ampicilin


organism: Staphylococcus aureus


organism: Stenotrophomonas maltophilia


substrate_name: ampicillin


organism: Arabidopsis thaliana

substrate_name: ADP


organism: Corynebacterium glutamicum


organism: Entamoeba histolytica

substrate_name: phosphoenolpyruvate


substrate_name: Unknown


organism: Treponema pallidum

substrate_name: Penicillin G; H2O


organism: Yersinia enterocolitica

substrate_name: cefalotin


organism: Yersinia ruckeri

substrate_name: cefuroxime


organism: Homo sapiens

substrate_name: Phosphoenolpyruvate; ADP


substrate_name: ADP; Phosphoenolpyruvate


organism: Lactococcus lactis subsp. cremoris


organism: Lactococcus lactis subsp. lactis


organism: Leishmania mexicana


organism: Mus musculus


organism: Oncorhynchus mykiss

substrate_name: Phosphoenolpyruvate; Phosphate; AMP


organism: Oryctolagus cuniculus

substrate_name: Phosphoenolpyruvate; dADP


organism: Plasmodium falciparum


organism: Rattus norvegicus


organism: Bacillus licheniformis

substrate_name: H2O; Phenoxymethylpenicillin


substrate_name: penicillin G


organism: Bacteroides fragilis


organism: Brachyspira pilosicoli

substrate_name: carbenicillin


organism: Burkholderia cenocepacia

substrate_name: ticarcillin


organism: Burkholderia pseudomallei

substrate_name: H2O; Nitrocefin


organism: Chryseobacterium indologenes

substrate_name: Sulbactam


organism: Citrobacter diversus

substrate_name: H2O; Benzylpenicillin


organism: Citrobacter freundii

substrate_name: Imipenem


organism: Stenotrophomonas maltophilia

substrate_name: biapenem


substrate_name: Nitrocefin; H2O


substrate_name: nitrocefin


organism: Saccharolobus solfataricus

substrate_name: phosphoenolpyruvate


organism: Saccharomyces cerevisiae


organism: Selenomonas ruminantium


organism: Thermofilum pendens

substrate_name: ADP


organism: Toxoplasma gondii

substrate_name: Unknown


organism: Trachemys scripta elegans


organism: Trichomonas vaginalis

substrate_name: Phosphoenolpyruvate; ADP


organism: Trypanosoma brucei


organism: Trypanosoma brucei brucei


organism: Trypanosoma congolense


organism: Ustilago maydis


organism: Vibrio cholerae serotype O1


organism: Zymomonas mobilis


organism: Aeromonas veronii bv. sobria


organism: Aliivibrio salmonicida


organism: Bacillus cereus

substrate_name: H2O; Cefotaxime


substrate_name: 6-Aminopenicillanate; H2O


substrate_name: H2O; Ampicillin


enzyme_display_name: thioredoxin-disulfide reductase (NADPH)

organism: Drosophila melanogaster


organism: Mus musculus

substrate_name: 5,5'-dithiobis(2-nitrobenzoic acid)


substrate_name: 5,5'-Dithiobis(2-nitrobenzoic acid)


substrate_name: H+; NADPH; 5,5'-Dithiobis(2-nitrobenzoic acid)


substrate_name: Hydroxyethyl disulfide


substrate_name: hydrogen peroxide


substrate_name: thioredoxin


substrate_name: thioredoxin disulfide


mutation_signature: truncated mutant enzyme (missing residues CUG from the C-terminus) so that Gly521 is the C-terminal amino acid


organism: Plasmodium falciparum

substrate_name: H+; NADPH; Methyl methanethiolsulfonate


substrate_name: Methyl methanethiolsulfonate


organism: Pseudomonas fluorescens

substrate_name: H+; NADPH; Oxidized thioredoxin


organism: Rattus norvegicus

substrate_name: Dithionitrobenzoic acid; NADPH; H+


substrate_name: Lipoamide


organism: Hordeum vulgare subsp. vulgare

substrate_name: Hordeum vulgare thioredoxin 2 mutant E86A


substrate_name: Hordeum vulgare thioredoxin 2


substrate_name: Arabidopsis thaliana thioredoxin 3


substrate_name: Hordeum vulgare thioredoxin 2 mutant I51G


organism: Leptospira biflexa serovar Patoc

substrate_name: NADPH


organism: Medicago truncatula

substrate_name: 5,5'-dithiobis(2-nitrobenzoic acid)


organism: Methanosarcina acetivorans

substrate_name: H+; NADH; 5,5'-Dithiobis(2-nitrobenzoic acid)


organism: Arabidopsis thaliana


organism: Arthrospira platensis

substrate_name: H+; NADPH; 5,5'-Dithiobis(2-nitrobenzoic acid)


organism: Babesia bovis

substrate_name: 5,5'-dithio-bis(2-nitrobenzoic acid)


organism: Bos taurus

substrate_name: Oxidized glutaredoxin; NADPH; H+


mutation_signature: truncated enzyme (missing residues CCS from the C-terminus) so that Ser488 is the C-terminal amino acid truncated enzyme (missing residues CCS from the C-termin


organism: Escherichia coli


organism: Euglena gracilis


substrate_name: NADH

mutation_signature: truncated mutant


organism: Saccharolobus solfataricus

substrate_name: thioredoxin


organism: Triticum aestivum


enzyme_display_name: arginine kinase

organism: Cissites cephalotes

substrate_name: L-Arg; ATP


organism: Daphnia magna

substrate_name: ATP; L-arginine


organism: Euphausia superba

substrate_name: L-arginine; ATP


substrate_name: L-Arginine


organism: Fenneropenaeus chinensis

substrate_name: L-Arginine; ATP; L-Arginine; ATP; L-Arginine phosphate; ADP


organism: Frankliniella occidentalis

substrate_name: L-Arginine; ATP; L-Arginine; ATP; L-Arginine phosphate; ADP; L-arginine

source_db: sabio_rk; brenda


organism: Haemonchus contortus


organism: Limulus polyphemus

substrate_name: L-Arginine phosphate


substrate_name: ADP


substrate_name: L-Arginine phosphate; ADP; L-Arginine phosphate; ADP; L-Arginine; ATP; ADP; L-Arginine phosphate


organism: Metapenaeus ensis

substrate_name: ATP (at pH 8.5 and 30 degrees Celsius)


organism: Penaeus vannamei

substrate_name: ATP (at pH 8.6 and 30 degrees Celsius)


organism: Tetrahymena pyriformis

substrate_name: ATP


organism: Toxocara canis

substrate_name: L-Arg


organism: Tribolium castaneum


substrate_name: Nomega-phospho-L-arginine


organism: Trypanosoma brucei brucei


organism: Trypanosoma cruzi


organism: Abyssogena kaikoi


organism: Anthopleura japonica


organism: Ascaris suum


organism: Caenorhabditis elegans


enzyme_display_name: Arginine kinase


organism: Locusta migratoria manilensis

substrate_name: L-arginine


organism: Lucilia cuprina


enzyme_display_name: Arginine kinase Met e 2

substrate_name: ATP; L-Arginine


organism: Nautilus pompilius


organism: Neocaridina denticulata


organism: Octopus vulgaris


organism: Polybetes pythagoricus


organism: Sabellastarte spectabilis


organism: Sepioteuthis lessoniana


organism: Teladorsagia circumcincta


organism: Tetrahymena pyriformis


organism: Bos taurus

substrate_name: thioredoxin


organism: Drosophila melanogaster

substrate_name: NADPH (at pH 7.4)


organism: Homo sapiens


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: TRX1 (at pH 7.4)


organism: Rattus norvegicus


organism: Gallus gallus

substrate_name: deoxyguanosine


substrate_name: deoxycytidine


organism: Xenopus laevis


enzyme_display_name: peptide deformylase

organism: Arabidopsis thaliana

substrate_name: N-Formyl-Met-Ala-Ser


substrate_name: H2O; Formyl-L-methionyl peptide


substrate_name: N-Formyl-Met-Ser-Asn-Glu


substrate_name: N-Formyl-Nle-Ala-Ser


substrate_name: N-Formyl-Nva-Ala-Ser


substrate_name: N-Formyl-Met-Leu-Phe


substrate_name: N-Formyl-Met-Leu-Glu


substrate_name: Formyl-L-methionyl peptide


substrate_name: N-Formyl-Phe-Ala-Ser


substrate_name: Formyl-L-methionyl peptide; H2O


substrate_name: H2O; N-Formyl-Met-Leu-p-nitroanilide


organism: Escherichia coli


substrate_name: formyl-Met-Ala-Ser


substrate_name: N-Formyl-Met-Leu


substrate_name: N-Formyl-L-methionine


substrate_name: H2O; N-Formyl-L-methionine


organism: Helicobacter pylori


substrate_name: N-formyl-Met-Leu-rho-nitroanilide


organism: Leptospira interrogans

substrate_name: N-formyl-Met-Ala-Ser


organism: Mycobacterium tuberculosis

substrate_name: N-formyl-Met-Ala


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Solanum lycopersicum


substrate_name: 5,5'-dithiobis(2-nitrobenzoic acid)


substrate_name: Lipoamide


organism: Hordeum vulgare

substrate_name: Hordeum vulgare thioredoxin disulfide h2


organism: Medicago truncatula


organism: Meleagris gallopavo

substrate_name: NADPH


organism: Methanosarcina acetivorans


organism: Mus musculus

substrate_name: thioredoxin


mutation_signature: truncated thioredoxin reductase missing its final eight amino acids


organism: Plasmodium berghei

substrate_name: dithionitrobenzene


organism: Plasmodium falciparum

substrate_name: methylseleninate


substrate_name: DTNB


substrate_name: H2O; Formyl-L-methionyl peptide


substrate_name: Formyl-L-methionyl peptide; H2O


organism: Staphylococcus epidermidis

substrate_name: N-formyl-L-Met-L-Ala-L-Ser


organism: Streptococcus agalactiae

substrate_name: Unknown


organism: Vibrio phage VP16T

substrate_name: formyl-Met-Ala-Ser


organism: Drosophila melanogaster


organism: Entamoeba histolytica


organism: Escherichia coli

substrate_name: glutaredoxin 4


substrate_name: thioredoxin-R


organism: Haemonchus contortus


organism: Homo sapiens


enzyme_display_name: pyruvate kinase

organism: Bos taurus

substrate_name: Phosphoenolpyruvate; ADP


organism: Ricinus communis


organism: Spinacia oleracea


organism: Unknown

substrate_name: ATP


substrate_name: N-formylmethionyl-Leu-p-nitroanilide


substrate_name: H2O; Cephalothin


organism: Apostichopus japonicus

substrate_name: L-Arg


organism: Cissites cephalotes


organism: Corbicula japonica


organism: Triticum aestivum

substrate_name: NADPH


organism: Saccharomyces cerevisiae


organism: Streptococcus mutans


organism: Toxoplasma gondii


organism: Trypanosoma brucei


organism: Abyssogena kaikoi


organism: Anthopleura japonica


substrate_name: L-arginine


organism: Anopheles gambiae

substrate_name: 5,5'-dithiobis(2-nitrobenzoic acid)


organism: Arabidopsis thaliana

substrate_name: thioredoxin


organism: Caenorhabditis elegans


organism: Cereibacter sphaeroides

substrate_name: reductase


organism: Corynebacterium nephridii

substrate_name: thioredoxin C-2


organism: Drosophila melanogaster

substrate_name: methylseleninate


organism: Plasmodium falciparum

substrate_name: DTNB


organism: Rattus norvegicus


substrate_name: thioredoxin 3


substrate_name: thioredoxin 2


organism: Schistosoma mansoni

mutation_signature: truncated recombinant enzyme (lacking the last two amino acids Sec597-Gly598)


mutation_signature: Unknown


organism: Solanum lycopersicum

substrate_name: Insulin; Reduced thioredoxin


organism: Spinacia oleracea


organism: Limulus polyphemus

substrate_name: ADP


organism: Locusta migratoria

substrate_name: Unknown


organism: Locusta migratoria manilensis

substrate_name: ATP


organism: Corbicula japonica


organism: Crassostrea sp.


organism: Ctenocephalides felis


organism: Desulfotalea psychrophila


enzyme_display_name: peroxidase

organism: Aggregatibacter actinomycetemcomitans


organism: Amphitrite ornata


organism: Amycolatopsis sp.


organism: Armoracia rusticana

substrate_name: H2O2; 2,4-Dichlorophenol


substrate_name: N-Acetyl-L-tryptophanamide


substrate_name: 2-Chloro-4-methoxyphenol; H2O2


substrate_name: L-Dopa; H2O2


substrate_name: guaiacol


substrate_name: H2O2 / 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid)


substrate_name: 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid); H2O2 / 2,2'-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) / H2O2 / H2O / Oxidized 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) / Guaiacol; H2O2 / Guaiacol / Oxidized donor / 4-Cresol; H2O2 / 4-Cresol / 4-Methylcatechol


substrate_name: Guaiacol


organism: Chromolaena odorata

substrate_name: pyrogallol


organism: Fagopyrum esculentum

substrate_name: ascorbic acid


organism: Ficus carica


organism: Nicotiana tabacum


organism: Arabidopsis thaliana

substrate_name: phosphoenolpyruvate (for the phosphatase activity)


organism: Auricularia auricula-judae

substrate_name: 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) (Dye-decolorizing peroxidase AauDyP1, at pH 4.5)


organism: Bubalus bubalis

substrate_name: 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (at pH 6.0 and 60 degrees Celsius)


organism: Exidia glandulosa


organism: Mycena epipterygia


organism: Mycetinis scorodonius


organism: Sus scrofa

substrate_name: cloride


organism: Taiwanofungus camphoratus

substrate_name: veratryl alcohol


organism: Anabaena sp.

substrate_name: Reactive Blue 5


substrate_name: 4-Methoxyphenol; H2O2


organism: Armoracia sp.


organism: Artocarpus heterophyllus


organism: Beta vulgaris


organism: Bjerkandera adusta

substrate_name: Pentachlorophenol


organism: Boucerosia umbellata


organism: Brassica napus


organism: Brassica oleracea

substrate_name: H2O2; Guaiacol


organism: Euphorbia characias


organism: Homo sapiens

substrate_name: 3,3',5,5'-Tetramethylbenzidine; H2O2


organism: Lepidium draba


organism: Neisseria gonorrhoeae


organism: Pleurotus eryngii


substrate_name: Reactive Black 5


organism: Trachycarpus fortunei


organism: Brassica oleracea var. capitata f. rubra

substrate_name: guaiacol


organism: Brassica rapa


organism: Calotropis procera

substrate_name: o-Dianisidine


organism: Camellia sinensis


organism: Capsicum annuum


organism: Citrus jambhiri


organism: Commiphora gileadensis


organism: Coprinopsis cinerea

substrate_name: 2,2'-Dihydroxyazobenzene; H2O2


organism: Cucumis melo

substrate_name: 3,4-dihydroxyphenylacetic acid


organism: Cucumis melo var. cantalupo


organism: Cucumis melo var. inodorus


organism: Cynara cardunculus

substrate_name: ferulic acid


organism: Amycolatopsis sp. (strain ATCC 39116 / 75iv2)

substrate_name: ABTS


organism: Zea mays

substrate_name: Unknown


organism: Zinnia elegans

substrate_name: p-coumaryl alcohol (in the presence of 10.2 uM H2O2, for a partially glycosylated enzyme)


organism: Armoracia rusticana


substrate_name: Guaiacol


organism: Bacillus altitudinis

substrate_name: Sinapoylcholine


substrate_name: sinapate


substrate_name: H2O2; Sinapate


organism: Bos taurus

substrate_name: N-Acetyl-L-tryptophanamide


organism: Cucumis sativus

substrate_name: H2O2; 4-Methoxy-alpha-naphthol


organism: Euphorbia characias


organism: Cytisus multiflorus


organism: Elais guineensis


organism: Elizabethkingia meningoseptica


organism: Escherichia coli

substrate_name: L-tyrosine


organism: Fragaria vesca


organism: Fragaria x ananassa


organism: Glycine max


organism: Homo sapiens

substrate_name: Br-


organism: Ipomoea carnea


organism: Lepidium sativum


organism: Lupinus albus

substrate_name: H2O2; Guaiacol


organism: Momordica charantia


organism: Locusta migratoria manilensis

substrate_name: L-Arg


organism: Manduca sexta

substrate_name: L-(+)-(S)-canavanine


organism: Molpadia arenicola


organism: Musca domestica


organism: Myzostoma cirriferum

substrate_name: ATP


organism: Paracentrotus lividus

substrate_name: ADP


organism: Paramecium tetraurelia

substrate_name: L-arginine


organism: Penaeus chinensis


organism: Periplaneta americana


organism: Sabella pavonina

substrate_name: D-Arg


organism: Sabellastarte spectabilis


organism: Mycobacterium avium


organism: Neurospora crassa


organism: Oryza sativa


organism: Ovis aries

substrate_name: SCN-


organism: Pelargonium graveolens


organism: Persea americana

substrate_name: pyrogallol


organism: Plasmodium falciparum

substrate_name: guaiacol


organism: Pleurotus ostreatus

substrate_name: sinapinic acid


organism: Prunus persica


organism: Pyrococcus furiosus

substrate_name: rubredoxin


organism: Raphanus sativus


organism: Raphanus sativus var. niger


organism: Steinernema carpocapsae


organism: Sthenoteuthis oualaniensis


organism: Sulfurovum lithotrophicum


organism: Torpedo californica

substrate_name: ADP; L-Arginine phosphate


organism: Tribolium castaneum


organism: Trypanosoma brucei


organism: Trypanosoma cruzi

substrate_name: Unknown


organism: Arabidopsis thaliana

substrate_name: N-formyl-Met-Leu-Glu


organism: Sclerocarya birrea


organism: Solanum betaceum


organism: Solanum melongena


organism: Sorghum bicolor


organism: Streptomyces lividans


organism: Triticum aestivum


organism: Vigna radiata


organism: Locusta migratoria manilensis


organism: Bacillus subtilis

substrate_name: N-formyl-Met-Ala-Ser


organism: Borreliella burgdorferi


organism: Chlamydia trachomatis


organism: Escherichia coli


substrate_name: N-formyl-phenylglycinol


substrate_name: N-formylmethionylleucyl-p-nitroanilide


substrate_name: N-formyl-L-Met-L-Val

mutation_signature: truncated zinc deformylase truncated zinc deformylase


mutation_signature: truncated cobalt deformylase truncated cobalt deformylase


mutation_signature: truncated Zn-PDF truncated Zn-PDF


mutation_signature: truncated Co-PDF truncated Co-PDF


organism: Haemophilus influenzae

substrate_name: formyl-Met-Ala-Ser


organism: Homo sapiens

substrate_name: formyl-L-Met-Leu-p-nitroanilide


organism: Legionella pneumophila


organism: Mycobacterium tuberculosis

substrate_name: N-formyl-L-Met-L-Ala


substrate_name: formyl-Met-Ala


organism: Solanum lycopersicum


organism: Staphylococcus aureus


organism: Streptococcus pneumoniae


organism: Trypanosoma cruzi


organism: Aeromonas sobria

substrate_name: H2O; Imipenem


organism: Enterobacter cloacae

substrate_name: H2O; Nitrocefin


organism: Klebsiella pneumoniae

substrate_name: H2O; Benzylpenicillin


organism: Stenotrophomonas maltophilia

substrate_name: Cefdinir; H2O


enzyme_display_name: methionine adenosyltransferase

organism: Methanocaldococcus jannaschii

substrate_name: L-methionine


substrate_name: ATP


organism: Mus musculus


substrate_name: Phosphoenolpyruvate; ADP


substrate_name: phosphoenolpyruvate


organism: Saccharomyces cerevisiae


organism: Bacillus subtilis

substrate_name: ATP; H2O; L-Methionine


organism: Catharanthus roseus


organism: Corynebacterium glutamicum


organism: Escherichia coli

substrate_name: L-Methionine; ATP; H2O


substrate_name: tripolyphosphate


substrate_name: L-Methionine


organism: Mycolicibacterium smegmatis

substrate_name: L-methionine; ATP


organism: Plasmodium falciparum

substrate_name: ATP; L-methionine


organism: Pyrococcus furiosus


organism: Rattus norvegicus

substrate_name: ATP; methionine


substrate_name: methionine; ATP


substrate_name: L-Methionine; ATP; H2O; L-Methionine; ATP; H2O; Diphosphate; S-Adenosyl-L-methionine; Phosphate


organism: Homo sapiens


substrate_name: S-(-)-methioninol


organism: Saccharolobus solfataricus


substrate_name: L-ethionine


organism: Streptomyces avermitilis


organism: Thermococcus kodakarensis


organism: Thermus thermophilus


enzyme_display_name: S-adenosylmethionine synthase isoform type-2


enzyme_display_name: S-adenosylmethionine synthase

organism: Leishmania donovani


organism: Methanocaldococcus jannaschii


organism: Trichomonas vaginalis


organism: Trypanosoma brucei


organism: Ustilago maydis


organism: Zymomonas mobilis


enzyme_display_name: beta-lactamase

organism: Pseudomonas aeruginosa

substrate_name: H2O; Penicillin G


organism: Mus musculus

substrate_name: Unknown


organism: Unknown

substrate_name: L-methionine


organism: Catharanthus roseus


organism: Escherichia coli (strain K12)


organism: Mammalia


organism: Saccharomyces cerevisiae


organism: Streptomyces xinghaiensis

substrate_name: ATP


organism: Trypanosoma brucei brucei


organism: Acacia koa

substrate_name: L-methionine (at 50 degrees Celsius)


organism: Bacteroides fragilis


organism: Bos taurus


organism: Cryptosporidium parvum


organism: Escherichia coli


substrate_name: S-adenosyl-L-methionine


organism: Felis catus


organism: Homo sapiens


organism: Lactiplantibacillus paraplantarum


organism: Lactiplantibacillus plantarum


organism: Lathyrus oleraceus


organism: Leishmania infantum


organism: Limosilactobacillus fermentum


organism: Limosilactobacillus reuteri


organism: Macaca mulatta


enzyme_display_name: carbonic anhydrase


organism: Methanosarcina thermophila


organism: Methanothermobacter thermautotrophicus


enzyme_display_name: GDP-D-glucose phosphorylase

organism: Caenorhabditis elegans

substrate_name: GDP-D-glucose (at 26 degrees Celsius)


substrate_name: GDP-D-glucose (at 31 degrees Celsius)


substrate_name: phosphate


substrate_name: GDP-alpha-D-glucose


enzyme_display_name: beta-glucosidase

organism: Acetivibrio thermocellus


organism: Agroathelia rolfsii


organism: Agrobacterium tumefaciens


organism: Alternaria alternata

substrate_name: cellobiose


organism: Aspergillus fumigatus


organism: Aspergillus japonicus


organism: Fusarium proliferatum

substrate_name: ginsenoside Rg3


organism: Saccharomyces cerevisiae

substrate_name: Phosphoenolpyruvate; ADP


organism: Amycolatopsis methanolica


organism: Arabidopsis thaliana


organism: Bos taurus


organism: Chlamydia trachomatis


organism: Corynebacterium glutamicum


organism: Escherichia coli


organism: Homo sapiens


organism: Rattus norvegicus


organism: Ricinus communis


enzyme_display_name: xylulokinase

organism: Escherichia coli (strain K12)

substrate_name: D-xylulose


organism: Klebsiella aerogenes


organism: Saccharococcus caldoxylosilyticus


organism: Scheffersomyces stipitis


organism: Toxoplasma gondii


substrate_name: D-xylulose (at pH 8)


organism: Aspergillus niger


substrate_name: ATP; D-Xylulose


substrate_name: D-arabitol


organism: Halorhabdus utahensis


substrate_name: D-Xylulose


organism: Mucor circinelloides


organism: Thermotoga maritima


substrate_name: (Polyphosphate)n


enzyme_display_name: kojibiose phosphorylase

organism: Pyrococcus sp.


organism: Citrus maxima

substrate_name: UDP-L-rhamnose; Prunin


organism: Amycolatopsis orientalis

substrate_name: UDP-L-epi-vancosamine


substrate_name: desvancosaminyl-vancomycin


substrate_name: dTDP-beta-L-daunosamine


organism: Gardenia jasminoides

substrate_name: beta-D-glucosyl crocetin


substrate_name: bis(beta-D-glucosyl) crocetin


organism: Panax ginseng

substrate_name: ginsenoside C-K


substrate_name: (20S)-ginsenoside Rh2


enzyme_display_name: taxadiene 5alpha-hydroxylase

organism: Taxus cuspidata


substrate_name: O2; Reduced acceptor; Taxa-4(5),11(12)-diene


organism: Homo sapiens


substrate_name: Piceid


substrate_name: H+; NADPH; Testosterone; O2


substrate_name: Resveratroloside


enzyme_display_name: ent-sandaracopimaradiene 3-hydroxylase

organism: Oryza sativa

substrate_name: ent-Cassa-12,15-diene; O2; H+; NADPH


enzyme_display_name: phenylacetonitrile alpha-monooxygenase

organism: Chamberlinius hualienensis

substrate_name: 3-methyl phenylacetonitrile


substrate_name: 2-methyl phenylacetonitrile


substrate_name: phenylacetonitrile


enzyme_display_name: pentalenic acid synthase

organism: Streptomyces avermitilis

substrate_name: Compactin


substrate_name: diclofenac


enzyme_display_name: isopenicillin-N synthase

organism: Cephalosporium acremonium


enzyme_display_name: (-)-pinoresinol reductase

organism: Arabidopsis thaliana

substrate_name: (-)-pinoresinol


organism: Camellia sinensis var. sinensis


enzyme_display_name: NAD(P)H oxidase (H2O-forming)

organism: Thermococcus kodakarensis

substrate_name: NADH


organism: Thermococcus profundus

substrate_name: NADPH


enzyme_display_name: caffeoyl-CoA O-methyltransferase

substrate_name: eriodictyol


enzyme_display_name: MMP 1-O-methyltransferase

organism: Mycolicibacterium hassiacum


enzyme_display_name: pinosylvin synthase

organism: Pinus sylvestris

substrate_name: Malonyl-CoA; Cinnamoyl-CoA


enzyme_display_name: demethoxycurcumin synthase

organism: Curcuma longa


enzyme_display_name: glycine C-acetyltransferase

organism: Escherichia coli

substrate_name: Glycine; Acetyl-CoA


organism: Thermus thermophilus


enzyme_display_name: trehalose 6-phosphate phosphorylase

organism: Badhamia polycephala

substrate_name: alpha,alpha-trehalose 6-phosphate


organism: Lactococcus lactis

substrate_name: beta-D-glucose 1-phosphate


organism: Lactococcus lactis subsp. lactis

substrate_name: Phosphate; Trehalose 6-phosphate


substrate_name: Phosphate; Kojibiose


enzyme_display_name: gallate dioxygenase

organism: Sphingobium sp. SYK-6

substrate_name: gallate


enzyme_display_name: Gallate dioxygenase

organism: Sphingomonas paucimobilis


organism: Synechocystis sp.

substrate_name: O2; all-trans-8'-apo-beta-Carotenal


organism: Streptomyces coeruleorubidus


enzyme_display_name: Methylxanthine N1-demethylase NdmA

organism: Pseudomonas putida

substrate_name: theophylline


substrate_name: Caffeine


substrate_name: paraxanthine


enzyme_display_name: Methylxanthine N3-demethylase NdmB


substrate_name: Theobromine


enzyme_display_name: Tabersonine 16-hydroxylase 1

organism: Catharanthus roseus

substrate_name: H+; NADPH; O2; Tabersonine


substrate_name: tabersonine


organism: Arabidopsis thaliana


organism: Goniophlebium amoenum

substrate_name: caffeoyl-CoA


substrate_name: quercetin


organism: Linum usitatissimum


organism: Mesembryanthemum crystallinum

substrate_name: eriodictyol


substrate_name: quercetagetin


organism: Plagiochasma appendiculatum


organism: Pyrus x bretschneideri


organism: Escherichia coli


substrate_name: D-mannitol[side 1]


organism: Methanocaldococcus jannaschii

substrate_name: GTP


substrate_name: Adenosyl cobinamide phosphate


enzyme_display_name: cardiolipin synthase (CMP-forming)

substrate_name: CDP-dioleoylglycerol


organism: Saccharomyces cerevisiae


enzyme_display_name: thiosulfate--thiol sulfurtransferase

organism: Homo sapiens

substrate_name: thiosulfate


organism: Ommastrephes sloanei

substrate_name: 3'-Phosphoadenylyl sulfate; Chondroitin sulfate A


organism: Rhodococcus erythropolis


enzyme_display_name: S-inosyl-L-homocysteine hydrolase

substrate_name: Inosine


enzyme_display_name: C5a peptidase

organism: Streptococcus pyogenes

substrate_name: Peptide; H2O


substrate_name: C75-BODIPY-labeled recombinant human C5a peptide


substrate_name: H2O; CXCL8


enzyme_display_name: complement subcomponent C1r

substrate_name: N-Acetyl-Gly-Lys methyl ester


substrate_name: N-Acetyl-Gly-Lys methyl ester; H2O


organism: Mus musculus

substrate_name: Fetuin glycopeptide I; H2O


enzyme_display_name: arylformamidase

organism: Bacillus anthracis

substrate_name: N-formyl-L-kynurenine


organism: Burkholderia cenocepacia


organism: Cupriavidus metallidurans

substrate_name: L-Formylkynurenine


substrate_name: H2O; L-Formylkynurenine


organism: Drosophila melanogaster


enzyme_display_name: caffeoyl-CoA O-methyltransferase

organism: Vanilla planifolia

substrate_name: tricetin


organism: Vitis vinifera

substrate_name: cyanidin 3-O-glucoside


enzyme_display_name: methionine S-methyltransferase

organism: Wollastonia biflora

substrate_name: L-Methionine; S-Adenosyl-L-methionine


organism: Medicago sativa


enzyme_display_name: indole-3-acetate O-methyltransferase

organism: Arabidopsis thaliana


organism: Oryza sativa Japonica Group

substrate_name: S-adenosyl-L-methionine


enzyme_display_name: MMP 1-O-methyltransferase

organism: Mycolicibacterium hassiacum


organism: Panax ginseng

substrate_name: ginsenoside F2


organism: Homo sapiens


organism: Streptomyces hygroscopicus subsp. limoneus

substrate_name: GDP-valienol


enzyme_display_name: alkylcobalamin dealkylase

substrate_name: Methylcobalamin; Glutathione


enzyme_display_name: 3-aminobutanoyl-CoA transaminase

organism: Candidatus Cloacimonas acidaminovorans


substrate_name: pyruvate


organism: Bacillus subtilis


organism: Zea mays


enzyme_display_name: diaminobutyrate--pyruvate transaminase

organism: Pseudomonas aeruginosa


substrate_name: Pyruvate; L-2,4-Diaminobutanoate


organism: Staphylococcus aureus

substrate_name: 2',3'-Cyclic GMP


substrate_name: H2O; Bis-4-nitrophenyl phosphate


substrate_name: Bis-4-nitrophenyl phosphate


substrate_name: 2',3'-Cyclic AMP


organism: Bifidobacterium longum


organism: Kribbella flavida


enzyme_display_name: exo beta-1,2-glucooligosaccharide sophorohydrolase (non-reducing end)

organism: Parabacteroides distasonis


organism: Streptococcus pyogenes

substrate_name: Peptide


substrate_name: ATP


enzyme_display_name: glycerate 2-kinase

organism: Escherichia coli


substrate_name: ATP; D-Glycerate


substrate_name: D-Glycerate


organism: Escherichia coli K-12


substrate_name: (R)-glycerate


organism: Picrophilus torridus


organism: Pyrococcus horikoshii

substrate_name: D-glycerate


organism: Saccharolobus solfataricus


organism: Synechocystis sp.


organism: Thermoplasma acidophilum


organism: Thermoproteus tenax


organism: Thermotoga maritima


organism: Berberis koetineana


organism: Medicago truncatula

substrate_name: isoliquiritigenin


enzyme_display_name: pinosylvin synthase

organism: Pinus densiflora

substrate_name: p-Coumaroyl-CoA


organism: Unknown

substrate_name: di-p-nitrophenyl phosphate


enzyme_display_name: cyanoalanine nitrilase

organism: Sorghum bicolor


enzyme_display_name: porphobilinogen synthase

organism: Homo sapiens

substrate_name: 5-aminolevulinic acid


organism: Pseudomonas aeruginosa


organism: Methanocaldococcus jannaschii

substrate_name: L-homocysteine


substrate_name: Inosine


substrate_name: S-Inosyl-L-homocysteine


enzyme_display_name: retinoid isomerohydrolase

organism: Bos taurus

substrate_name: H2O; All-trans-Retinyl palmitate


organism: Danio rerio

substrate_name: an all-trans retinyl ester


organism: Acinetobacter baumannii

substrate_name: D-mannitol 1-phosphate


enzyme_display_name: pseudouridine 5'-phosphatase

substrate_name: Pseudouridine 5'-phosphate; H2O


organism: Escherichia coli

substrate_name: p-nitrophenyl phosphate


substrate_name: bis-4-nitrophenyl phosphate


substrate_name: CDP-choline


enzyme_display_name: tabersonine 16-hydroxylase

organism: Catharanthus roseus

substrate_name: tabersonine


enzyme_display_name: (-)-pinoresinol reductase

organism: Arabidopsis thaliana

substrate_name: (-)-pinoresinol


substrate_name: (+)-pinoresinol


organism: Petunia hybrida

substrate_name: Unknown


organism: Medicago sativa

substrate_name: isoliquiritigenin


substrate_name: indole-3-acetic acid (IAA)


organism: Pinus strobus

substrate_name: cinnamoyl-CoA


organism: Pinus sylvestris


enzyme_display_name: glycine C-acetyltransferase

organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: L-glycine (with acetyl-CoA at pH 6 and at 70 degrees Celsius)


enzyme_display_name: kojibiose phosphorylase

organism: Thermoanaerobacter brockii

substrate_name: kojibiose


organism: Citrus maxima

substrate_name: prunin


substrate_name: UDP-alpha-D-galactose


organism: Mus musculus


organism: Homo sapiens


organism: Escherichia coli (strain K12)

substrate_name: glycerate


organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)

substrate_name: glycerate (at 50 degrees Celsius and at pH 7.3)


organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

substrate_name: glycerate (at 45 degrees Celsius and at pH 7.0)


organism: Streptomyces coeruleorubidus


enzyme_display_name: methylxanthine N(1)-demethylase

organism: Pseudomonas putida

substrate_name: theophylline (at pH 7.5 and 30 degrees Celsius)


enzyme_display_name: methylxanthine N(3)-demethylase

substrate_name: 3-methylxanthine (at pH 7.5 and 30 degrees Celsius)


substrate_name: tabersonine in a T16H/16OMT coupled system


enzyme_display_name: ent-sandaracopimaradiene 3-hydroxylase

organism: Oryza sativa subsp. japonica

substrate_name: ent-cassadiene


enzyme_display_name: phenylacetonitrile alpha-monooxygenase

organism: Prunus mume

substrate_name: phenylacetaldoxime (in the presence of NADPH at pH 7.6 and 30 degrees Celsius)


enzyme_display_name: NAD(P)H oxidase (H2O-forming)

organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: NADH


enzyme_display_name: kaempferol 4'-O-methyltransferase

organism: Solanum habrochaites

substrate_name: myricetin (in the presence of S-adenosylmethionine)


enzyme_display_name: MMP 1-O-methyltransferase

organism: Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849)


enzyme_display_name: demethoxycurcumin synthase

organism: Curcuma longa

substrate_name: feruloyl-CoA


substrate_name: kojibiose (at pH 7.5, 30 degrees Celsius)


organism: Amycolatopsis orientalis

substrate_name: devancoaminyl-vancomycin


enzyme_display_name: inosine/xanthosine triphosphatase

organism: Escherichia coli

substrate_name: xanthosine 5'-triphosphate


substrate_name: guanosine 5'-triphosphate


substrate_name: 2'-deoxyinosine 5'-triphosphate


substrate_name: inosine 5'-triphosphate


enzyme_display_name: D-ornithine/D-lysine decarboxylase

organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: D-Lysine


substrate_name: D-ornithine


enzyme_display_name: carboxynorspermidine decarboxylase

organism: Vibrio vulnificus

substrate_name: Carboxynorspermidine


substrate_name: carboxyspermidine


substrate_name: carboxynorspermidine


enzyme_display_name: 2-dehydro-3-deoxy-D-gluconate aldolase

organism: Picrophilus oshimae


organism: Picrophilus torridus


enzyme_display_name: porphobilinogen synthase


enzyme_display_name: arylformamidase

organism: Mus musculus

substrate_name: H2O; L-Formylkynurenine; H2O; L-Formylkynurenine; Formate; L-Kynurenine


substrate_name: N-formyl-L-kynurenine


organism: Pseudomonas aeruginosa


organism: Saccharomyces cerevisiae

source_db: brenda; skid


organism: Streptomyces coelicolor


enzyme_display_name: N-substituted formamide deformylase

organism: Arthrobacter pascens

substrate_name: N-benzylformamide; N-butylformamide


substrate_name: N-Benzylformamide; H2O; N-Benzylformamide; H2O; Formate; Benzylamine; N-Butylformamide; H2O; N-Butylformamide; Butylamine


enzyme_display_name: cyanoalanine nitrilase

organism: Lupinus angustifolius

substrate_name: H2O; 3-Cyano-L-alanine; H2O; 3-Cyano-L-alanine; L-Aspartate; NH3


enzyme_display_name: ADP-sugar diphosphatase

organism: Arabidopsis thaliana

substrate_name: ADP-ribose; H2O; ADP-ribose; H2O; AMP; D-Ribose 5-phosphate; ADPglucose; H2O; ADPglucose; D-Glucose 1-phosphate


enzyme_display_name: UDP-2,3-diacylglucosamine diphosphatase

organism: Caulobacter vibrioides


organism: Haemophilus influenzae


organism: Klebsiella pneumoniae

substrate_name: Unknown


organism: Klebsiella pneumoniae subsp. pneumoniae


organism: Escherichia coli (strain K12)

substrate_name: mannitol phosphorylation


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: adenosylcobinamide phosphate


enzyme_display_name: cardiolipin synthase (CMP-forming)

substrate_name: phosphatidylglycerol (dioleoyl species)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: phosphatidylglycerol


enzyme_display_name: thiosulfate--thiol sulfurtransferase

organism: Homo sapiens

substrate_name: glutathione


organism: Nototodarus sloanii

substrate_name: PAPS


enzyme_display_name: retinoid isomerohydrolase

organism: Bos taurus

substrate_name: all-trans-retinyl palmitate


organism: Danio rerio

substrate_name: 11-cis retinol


organism: Gallus gallus


enzyme_display_name: pseudouridine 5'-phosphatase


organism: Bacillus subtilis (strain 168)

substrate_name: unsaturated rhamnogalacturonan disaccharide (at pH 6 and 30 degrees Celsius)


enzyme_display_name: adenylylsulfatase

substrate_name: P(1)-P(3)-bis(5'-adenosyl) triphosphate


organism: Vibrio alginolyticus

substrate_name: carboxynorspermidine (at 37 degrees Celsius and pH 8.25)


organism: Vibrio vulnificus (strain CMCP6)

substrate_name: carboxynorspermidine


organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)

substrate_name: KDG (at 60 degrees Celsius and pH 6.2)


substrate_name: 5-aminolevulinic acid


substrate_name: 5-aminolevulinate at pH 7


organism: Gardenia jasminoides

substrate_name: beta-D-glucosyl crocetin


organism: Panax ginseng

substrate_name: protopanaxadiol (at pH 7 and 35 degrees Celsius)


substrate_name: ginsenoside Rh2 (at pH 8 and 40 degrees Celsius)


organism: Streptomyces hygroscopicus subsp. limoneus

substrate_name: GDP-valienol


enzyme_display_name: alkylcobalamin dealkylase


enzyme_display_name: 3-aminobutanoyl-CoA transaminase

organism: Cloacimonas acidaminovorans (strain Evry)


substrate_name: KMTB


substrate_name: PtdIns (in the absence of phosphatidylserine)


enzyme_display_name: glycerate 2-kinase

organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: ATP


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: adenosylcobinamide


organism: Rhodococcus qingshengii

substrate_name: HBPS


enzyme_display_name: S-inosyl-L-homocysteine hydrolase

organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: inosine (at pH 7.0 and 70 degrees Celsius)


substrate_name: unsaturated rhamnogalacturonan disaccharide (at pH 4 and 30 degrees Celsius)


organism: Mus musculus

substrate_name: fetuin glycopeptide I


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: asialofetuin


substrate_name: N-formyl-L-kynurenine


organism: Arthrobacter pascens

substrate_name: N-benzylformamide


organism: Arabidopsis thaliana

substrate_name: Ala(CN) (for the nitrilase activity)


organism: Lupinus angustifolius

substrate_name: Ala(CN)


substrate_name: ADP-D-ribose


organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)


organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)


substrate_name: adenosine 5'-phosphoramidate (at pH 6.8)


enzyme_display_name: isopenicillin-N synthase

organism: Hapsidospora chrysogena

substrate_name: Unknown


enzyme_display_name: (-)-pinoresinol reductase

organism: Thuja plicata

substrate_name: (-)-pinoresinol


enzyme_display_name: NAD(P)H oxidase (H2O-forming)

organism: Giardia duodenalis

substrate_name: NADH


enzyme_display_name: caffeoyl-CoA O-methyltransferase

organism: Ammi majus

substrate_name: quercetin


organism: Azadirachta indica

substrate_name: caffeic acid


organism: Camellia sinensis


organism: Citrus reticulata

substrate_name: tricetin


organism: Citrus sinensis

substrate_name: caffeoyl-CoA


organism: Medicago sativa


organism: Nicotiana tabacum


organism: Oryza sativa


organism: Triticum aestivum


enzyme_display_name: kaempferol 4'-O-methyltransferase

organism: Dianthus caryophyllus

substrate_name: S-Adenosyl-L-methionine; Kaempferol


enzyme_display_name: indole-3-acetate O-methyltransferase

organism: Illicium anisatum


organism: Populus trichocarpa

substrate_name: S-adenosyl-L-methionine


enzyme_display_name: MMP 1-O-methyltransferase

organism: Mycolicibacterium smegmatis


enzyme_display_name: pinosylvin synthase

organism: Pinus sylvestris

substrate_name: phenylpropionyl-CoA


enzyme_display_name: gallate dioxygenase

organism: Pseudomonas putida

substrate_name: gallate


organism: Sphingobium sp. SYK-6


enzyme_display_name: tabersonine 16-hydroxylase

organism: Catharanthus roseus

substrate_name: NADPH


enzyme_display_name: taxadiene 5alpha-hydroxylase

organism: Taxus cuspidata


organism: Taxus media


organism: Homo sapiens

substrate_name: taurochenodeoxycholate


enzyme_display_name: ent-sandaracopimaradiene 3-hydroxylase

substrate_name: ent-cassadiene


organism: Actinomyces sp.


organism: Amycolatopsis lactamdurans


organism: Flavobacterium sp.


enzyme_display_name: demethoxycurcumin synthase

organism: Curcuma longa


enzyme_display_name: glycine C-acetyltransferase

organism: Bos taurus

substrate_name: acetyl-CoA


organism: Escherichia coli

substrate_name: propionyl-CoA


organism: Thermus thermophilus


enzyme_display_name: trehalose 6-phosphate phosphorylase

organism: Lactococcus lactis ssp. lactis

substrate_name: glucose 6-phosphate


enzyme_display_name: kojibiose phosphorylase

substrate_name: D-glucose


organism: Lactobacillus acidophilus


organism: Thermoanaerobacter brockii

substrate_name: kojibiose


substrate_name: phosphate


substrate_name: beta-D-glucose 1-phosphate


organism: Citrus maxima

substrate_name: UDP-L-rhamnose


organism: Dipsacus asperoides

substrate_name: UDP-beta-L-rhamnose


organism: Panax major

substrate_name: protopanaxadiol


organism: Salinispora tropica

substrate_name: UDP-alpha-D-glucose


organism: Gallus gallus


organism: Mus musculus


organism: Oryctolagus cuniculus


organism: Rattus norvegicus


enzyme_display_name: alkylcobalamin dealkylase

organism: Homo sapiens

substrate_name: nitrocobalamin


organism: Solanum lycopersicum


enzyme_display_name: diaminobutyrate--pyruvate transaminase

organism: Halomonas elongata

substrate_name: L-glutamate


organism: Halorhodospira halochloris


organism: Pseudomonas aeruginosa

substrate_name: pyruvate


substrate_name: ATP


enzyme_display_name: glycerate 2-kinase

organism: Escherichia coli


organism: Hyphomicrobium methylovorum


organism: Picrophilus oshimae


organism: Pyrococcus horikoshii

substrate_name: (R)-glycerate


organism: Thermoplasma acidophilum


substrate_name: D-mannitol[side 1]


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: 5'-deoxyadenosylcobinamide phosphate


enzyme_display_name: cardiolipin synthase (CMP-forming)

substrate_name: egg yolk phosphatidylglycerol


enzyme_display_name: thiosulfate--thiol sulfurtransferase

organism: Acinetobacter calcoaceticus

substrate_name: cyanide


organism: Saccharomyces cerevisiae

substrate_name: glutathione


organism: squid

substrate_name: 3'-phosphoadenylyl sulfate


organism: Paenibacillus sp.


organism: Rhodococcus erythropolis


enzyme_display_name: retinoid isomerohydrolase

organism: Bos taurus

substrate_name: all-trans-retinyl palmitate


organism: Gallus gallus


organism: Homo sapiens

substrate_name: an all-trans-retinyl ester


organism: Sus scrofa


organism: Aspergillus nidulans

substrate_name: mannitol 1-phosphate


organism: Caloglossa continua

substrate_name: D-mannitol 1-phosphate


organism: Ectocarpus siliculosus


organism: Eimeria tenella


organism: Pyricularia oryzae


organism: Escherichia coli (strain K12)

substrate_name: fructose-1-P (with magnesium ions as cofactor and at pH 9)


substrate_name: 2-deoxyglucose-6-P (with manganese ions as cofactor and at pH 9)


enzyme_display_name: pseudouridine 5'-phosphatase

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: XMP


organism: Bacillus subtilis (strain 168)


substrate_name: Unknown


organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)

substrate_name: PEP (at pH 6.5)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)


organism: Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)

substrate_name: cyclobis-(1-6)-alpha-nigerosyl (CNN)


enzyme_display_name: exo beta-1,2-glucooligosaccharide sophorohydrolase (non-reducing end)

organism: Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)


enzyme_display_name: arylformamidase

organism: Bacillus anthracis

substrate_name: N-formyl-L-kynurenine


organism: Streptococcus bovis

substrate_name: H2O; D-Mannitol 1-phosphate


organism: Homo sapiens

substrate_name: pseudouridine 5'-phosphate


organism: Bacillus sp. (in: firmicutes)

substrate_name: bis(p-nitrophenyl)phosphate


organism: Bacillus subtilis


organism: Escherichia coli


organism: Fusarium culmorum

substrate_name: cyclic 2',3'-GMP


organism: Haemophilus influenzae


organism: Mycobacterium tuberculosis

substrate_name: p-nitrophenyl phosphate


organism: Myxococcus xanthus

substrate_name: cyclic 2',3'-AMP


organism: Proteus mirabilis


organism: Proteus vulgaris


organism: Shigella sonnei


organism: Vibrio alginolyticus


organism: Bacteroides thetaiotaomicron


organism: Bifidobacterium longum


enzyme_display_name: C5a peptidase

organism: Streptococcus pyogenes

substrate_name: SQLRANISHKDMQLGR


enzyme_display_name: complement subcomponent C1r

substrate_name: N-acetyl-Arg methyl ester


organism: Elizabethkingia meningoseptica

substrate_name: Fetuin glycopeptide


organism: Mus musculus


organism: Prunus amygdalus var. dulcis

substrate_name: bromelain undecapeptide


organism: Saccharomyces cerevisiae

substrate_name: asialo fetuin glycopeptide I


organism: Sus scrofa

substrate_name: Beta-aspartylglycosylamine


organism: Bos taurus


organism: Drosophila melanogaster


organism: Gallus gallus


organism: Neurospora crassa


organism: Ogataea henricii


organism: Oncorhynchus mykiss

substrate_name: N-formyl-DL-kynurenine


organism: Rattus sp.


organism: Streptomyces parvulus


substrate_name: Unknown


enzyme_display_name: N-substituted formamide deformylase

organism: Arthrobacter pascens

substrate_name: N-benzylformamide


enzyme_display_name: cyanoalanine nitrilase

organism: Brassica rapa


organism: Pseudomonas sp.


organism: Zea mays


enzyme_display_name: ADP-sugar diphosphatase

organism: Escherichia coli

substrate_name: ADP-ribose


organism: Rattus norvegicus

substrate_name: ADP-Rib


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: ADP-glucose


enzyme_display_name: adenylylsulfatase

substrate_name: Adenosine 5'-phosphosulfate; H2O


organism: Comamonas terrigena

substrate_name: adenosine 5'-phosphosulfate


enzyme_display_name: carboxynorspermidine decarboxylase

organism: Campylobacter jejuni

substrate_name: carboxyspermidine


organism: Eshraghiella crossota


organism: Vibrio alginolyticus

substrate_name: carboxynorspermidine


organism: Vibrio vulnificus


enzyme_display_name: porphobilinogen synthase

organism: Bos taurus


organism: Cereibacter sphaeroides


organism: Coturnix japonica


organism: Drosophila melanogaster


organism: Homo sapiens


organism: Ictalurus punctatus


organism: Lathyrus oleraceus


organism: Mus musculus


organism: Mycolicibacterium phlei


organism: Neurospora crassa


organism: Plasmodium falciparum


organism: Pseudomonas aeruginosa


organism: Pyrobaculum calidifontis


organism: Rattus sp.

substrate_name: 5-aminolevulinic acid


organism: Rhodobacter capsulatus


organism: Saccharomyces cerevisiae


organism: Tetradesmus obliquus


organism: Toxoplasma gondii


organism: Zea mays


organism: Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)

substrate_name: N-formyl-L-kynurenine


organism: Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)


organism: Drosophila melanogaster


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


enzyme_display_name: UDP-2,3-diacylglucosamine diphosphatase

organism: Escherichia coli (strain K12)


enzyme_display_name: inosine/xanthosine triphosphatase

substrate_name: ITP


enzyme_display_name: D-ornithine/D-lysine decarboxylase

organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


organism: Campylobacter jejuni subsp. jejuni serotype O:6 (strain 81116 / NCTC 11828)


organism: Pisum sativum


organism: Lathyrus oleraceus


organism: Glycyrrhiza echinata


organism: Medicago truncatula


organism: Methanosarcina barkeri

substrate_name: methyl-CoM


substrate_name: methylmercaptopropionate


enzyme_display_name: 2-deoxystreptamine glucosyltransferase

organism: Streptomyces kanamyceticus

substrate_name: UDP-D-glucose


organism: Rhodothermus marinus

substrate_name: CTP


substrate_name: 2-Deoxystreptamine; UDP-D-glucose


organism: Archaeoglobus fulgidus

substrate_name: 1L-myo-inositol 1-phosphate


substrate_name: UDP-N-acetyl-alpha-D-glucosamine


organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

substrate_name: CTP (at pH 7 and 90 degrees Celsius)


enzyme_display_name: type I site-specific deoxyribonuclease

organism: Escherichia coli

substrate_name: ATP


organism: Micrococcus luteus

substrate_name: DNA; ATP; H2O


organism: Pseudomonas sp. (strain ADP)

substrate_name: hydroxyatrazine


organism: Pseudomonas sp.

substrate_name: Hydroxyatrazine


substrate_name: H2O; Hydroxyatrazine


organism: Streptococcus pneumoniae


enzyme_display_name: D-amino-acid N-acetyltransferase

organism: Saccharomyces cerevisiae

substrate_name: D-serine


organism: Streptococcus pneumoniae (strain ATCC BAA-255 / R6)

substrate_name: glycerol-3-phosphate (at 37 degrees Celsius and at pH 7.4)


substrate_name: Acetyl-CoA; D-Serine


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: D-Serine


organism: Homo sapiens

substrate_name: glucosylceramide


substrate_name: UDP-D-galactose; Glucosylceramide


organism: Catharanthus roseus

substrate_name: UDP-alpha-D-glucose


substrate_name: 7-deoxyloganetic acid


substrate_name: UDP-galactose


organism: Rattus norvegicus


organism: Unknown

substrate_name: NAD+


organism: Azospirillum brasilense


organism: Rhodospirillum rubrum

substrate_name: NAD


organism: Bacillus subtilis (strain 168)

substrate_name: Unknown


organism: Dickeya chrysanthemi


enzyme_display_name: Glucuronoxylanase XynC

organism: Bacillus subtilis

substrate_name: H2O; 4-O-Methyl-D-glucuronoxylan


enzyme_display_name: albendazole monooxygenase

substrate_name: trimethylamine (at pH 8.5)


organism: Dicrocoelium dendriticum

substrate_name: albendazole S-oxide


organism: Ictalurus punctatus

substrate_name: H+; NADPH; O2; Albendazole


organism: Oncorhynchus mykiss


organism: Oreochromis sp.


organism: Escherichia coli

substrate_name: UDP-glucose


substrate_name: UDPglucose


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: lipopolysaccharide


organism: Salmonella typhimurium

substrate_name: UDPglucose; Lipopolysaccharide


substrate_name: beta-Alanine


substrate_name: 2-Oxoglutarate; L-3-Amino-isobutanoate


enzyme_display_name: [pyruvate, phosphate dikinase] kinase

organism: Arabidopsis thaliana

substrate_name: Pyruvate, phosphate dikinase; ADP


enzyme_display_name: molybdenum cofactor sulfurtransferase

substrate_name: L-Cysteine; 1,4-Dithiothreitol


organism: Homo sapiens

substrate_name: Benzamidoxime; NADH; H+


organism: Sus scrofa


enzyme_display_name: CoA:oxalate CoA-transferase

substrate_name: acetyl-CoA


substrate_name: oxalate


substrate_name: NAD+


organism: Zea mays

substrate_name: ADP


enzyme_display_name: carbonic anhydrase


substrate_name: ADP (at pH 6.8)


substrate_name: L-cysteine


substrate_name: benzamidoxime


organism: Acetobacter aceti

substrate_name: oxalate (at pH 6.7 and 25 degrees Celsius)


organism: Escherichia coli (strain K12)

substrate_name: acetyl-CoA (at pH 6.7 and 25 degrees Celsius)


enzyme_display_name: mannosyl-3-phosphoglycerate phosphatase

organism: Pyrococcus horikoshii


organism: Thermus thermophilus


organism: Bacteroides thetaiotaomicron


enzyme_display_name: N(1)-aminopropylagmatine ureohydrolase

organism: Thermococcus kodakarensis


substrate_name: agmatine


enzyme_display_name: prephenate decarboxylase

organism: Bacillus subtilis

substrate_name: prephenate


organism: Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)

substrate_name: GPG (at 30 degrees Celsius)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: glucosyl-3-phosphoglycerate (at 37 degrees Celsius)


organism: Persephonella marina (strain DSM 14350 / EX-H1)

substrate_name: GPG (at 70 degrees Celsius)


enzyme_display_name: coccolysin

organism: Enterococcus faecalis

substrate_name: Substance P


organism: Enterococcus faecalis subsp. liquefaciens

substrate_name: Insulin B chain; H2O


organism: Planktothrix agardhii


organism: Salinispora tropica


organism: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)

substrate_name: alpha-HBP (at pH 7.5 and 25 degrees Celsius)


organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

substrate_name: D-glycero-alpha-D-manno-heptose 1,7-bisphosphate (at pH 7.4)