enzyme_display_name: isocitrate dehydrogenase (NADP+)

organism: Rhodomicrobium vannielii


enzyme_display_name: isocitrate dehydrogenase (NADP(+))

substrate_name: NADP+

source_db: oed

verification_status: unverified

ki_display: Not reported

mutation_signature: Unknown

protein_accession_database: UniProt

source_license: CC BY 4.0

km_unit: mM


organism: Bifidobacterium longum

kcat_over_km_origin: calculated


verification_status: corrected


organism: Escherichia coli

substrate_name: isocitrate


organism: Acidithiobacillus thiooxidans

substrate_name: NAD+


organism: Bifidobacterium longum subsp. infantis


organism: Streptomyces lividans


enzyme_display_name: Isocitrate dehydrogenase [NADP]

organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)

substrate_name: NADP(+) (for native enzyme)

source_db: uniprot

kcat_display: Not reported

kcat_over_km_display: Not reported


substrate_name: isocitrate (for native enzyme)


organism: Thermus thermophilus

substrate_name: homoisocitrate

verification_status: verified


enzyme_display_name: isocitrate dehydrogenase (NAD(+))

organism: Hydrogenobacter thermophilus


organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)

substrate_name: D-threo-isocitrate


substrate_name: NADP(+)


enzyme_display_name: isocitrate dehydrogenase (NAD+)

organism: Methylococcus capsulatus

source_db: brenda


organism: Microcystis aeruginosa

substrate_name: DL-isocitrate


enzyme_display_name: L-iditol 2-dehydrogenase

organism: Bos taurus

substrate_name: D-fructose/L-sorbose


substrate_name: D-ribulose


substrate_name: NADH


organism: Caldococcus noboribetus


organism: Chlamydomonas reinhardtii


organism: Archaeoglobus fulgidus


organism: Mycolicibacterium phlei


organism: Methylobacillus flagellatus


substrate_name: Oxalosuccinate

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)


organism: Yarrowia lipolytica


enzyme_display_name: Isocitrate dehydrogenase [NADP], mitochondrial

organism: Sus scrofa

substrate_name: manganese


enzyme_display_name: L-lactate dehydrogenase

organism: Lactiplantibacillus pentosus

substrate_name: pyruvate (at pH 5)


enzyme_display_name: malate dehydrogenase (decarboxylating)

organism: Arabidopsis thaliana


enzyme_display_name: Isocitrate dehydrogenase [NADP] cytoplasmic

organism: Homo sapiens

substrate_name: magnesium chloride


km_display: Not reported


substrate_name: NADPH


substrate_name: NADP+


substrate_name: isocitrate


organism: Acinetobacter baumannii


organism: Saccharomyces cerevisiae

substrate_name: D-isocitrate


organism: Haloferax volcanii


substrate_name: NAD+


organism: Xylella fastidiosa


organism: Escherichia coli


ki_unit: mM


enzyme_display_name: phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

organism: Dicentrarchus labrax


enzyme_display_name: phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)


organism: Moorella thermoacetica


organism: Thermotoga maritima


substrate_name: D,L-isocitrate


substrate_name: oxalosuccinate


enzyme_display_name: phosphogluconate 2-dehydrogenase

organism: Burkholderia cepacia


organism: Avena fatua


organism: Zea mays


organism: Candida tropicalis


organism: Ricinus communis


organism: Catharanthus roseus


organism: Corynebacterium glutamicum

substrate_name: NADP+; 6-Phospho-D-gluconate


organism: Arthrospira platensis


organism: Burkholderia multivorans

substrate_name: NAD+; 6-Phospho-D-gluconate


organism: Beta vulgaris


organism: Corylus avellana


organism: Strongylocentrotus purpuratus


organism: Pseudomonas fluorescens


organism: Homo sapiens

substrate_name: Unknown


organism: Petroselinum crispum


organism: [Candida] boidinii


organism: Gryllus firmus


organism: Glycine max


substrate_name: 6-Phospho-D-gluconate; NADP+


organism: Lathyrus oleraceus


organism: Spinacia oleracea


organism: Neomoorella thermoacetica


organism: Synechocystis sp.


organism: Thermotoga maritima


organism: Ctenopharyngodon idella


organism: Limnospira platensis


enzyme_display_name: UniProt Q8IKT2

organism: Plasmodium falciparum

source_db: skid

source_license: CC BY-NC-ND 4.0


organism: Cyberlindnera jadinii


substrate_name: xylitol


substrate_name: L-threitol


enzyme_display_name: UniProt P52209


enzyme_display_name: UniProt P00349

organism: Ovis aries


enzyme_display_name: UniProt P00350

organism: Escherichia coli

source_license: CC BY 4.0; CC BY-NC-ND 4.0


enzyme_display_name: UniProt P38720

organism: Saccharomyces cerevisiae


organism: Moorella thermoacetica


organism: Dictyostelium discoideum


organism: [Candida] boidinii


organism: Oryctolagus cuniculus


organism: [Brevibacterium] flavum


organism: Trypanosoma brucei


organism: Dicentrarchus labrax


organism: Homo sapiens


organism: Trypanosoma cruzi


enzyme_display_name: isocitrate dehydrogenase (NADP+)

organism: Rhodopseudomonas palustris


enzyme_display_name: 6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic

organism: Spinacia oleracea

substrate_name: NADP


organism: Arabidopsis thaliana


organism: Nicotiana tabacum


organism: Pseudomonas sp.


organism: Saccharolobus solfataricus


organism: Mycobacterium tuberculosis

substrate_name: DL-isocitrate


organism: Rattus norvegicus


organism: Cupriavidus necator


organism: Microcystis aeruginosa


organism: Leishmania mexicana


organism: Pseudomonas psychrophila


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)(+)]

organism: Priestia megaterium

substrate_name: D-glucose


enzyme_display_name: Glucose 1-dehydrogenase

organism: Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4)

substrate_name: NAD(+) (at 40 degrees Celsius and pH 8.8)


substrate_name: NADP(+) (at 40 degrees Celsius and pH 8.8)


enzyme_display_name: Galactose 1-dehydrogenase

organism: Pseudomonas fluorescens

substrate_name: NADP(+)


substrate_name: D-galactose


organism: Leuconostoc mesenteroides


substrate_name: NADP+


substrate_name: D-glucose (at 40 degrees Celsius and pH 8.8)


substrate_name: D-xylose (at 40 degrees Celsius and pH 8.8)


organism: Dictyostelium discoideum


substrate_name: D-glucose 6-phosphate


organism: Trypanosoma cruzi


organism: Saccharomyces cerevisiae

substrate_name: D-Glucose 6-phosphate


substrate_name: glucose 6-phosphate


organism: Comamonas testosteroni

substrate_name: Fusidic acid


substrate_name: Isatin


organism: Escherichia coli


substrate_name: isocitrate


organism: Arabidopsis thaliana


organism: Bifidobacterium longum subsp. infantis


substrate_name: NAD+


organism: Archaeoglobus fulgidus


organism: Homo sapiens


organism: Plasmodium falciparum


organism: Colwellia maris


organism: Mesocricetus auratus


substrate_name: androsterone


substrate_name: benzenedihydrodiol


organism: Sus scrofa

substrate_name: NADPH


substrate_name: D-galactose 6-phosphate


organism: Mus musculus

substrate_name: 3-oxo-5beta-cholan-24-oic acid


substrate_name: glycolithocholic acid


substrate_name: cholic acid


substrate_name: Camphorquinone


substrate_name: geraniol


substrate_name: cis-benzene dihydrodiol


substrate_name: NADH


substrate_name: NADP+


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)+]

organism: Oncorhynchus mykiss


substrate_name: 2-deoxy-D-glucose 6-phosphate


substrate_name: D-xylose


organism: Pseudomonas putida


substrate_name: deoxycholate


substrate_name: cholate


organism: Bacillus sp. (in: Bacteria)

substrate_name: D-glucose


substrate_name: NAD+


organism: Rattus norvegicus


substrate_name: testosterone


organism: Priestia megaterium

substrate_name: beta-D-glucose


enzyme_display_name: L-gulonate 3-dehydrogenase

organism: Schwanniomyces occidentalis


substrate_name: D-gluconate


substrate_name: L-gulonate


substrate_name: 3-oxo-5beta-cholan-24-oic acid


substrate_name: NADPH


substrate_name: glycolithocholic acid


substrate_name: androsterone


substrate_name: Camphorquinone


protein_accession_database: NCBI Protein


substrate_name: androstanedione


organism: Meleagris gallopavo

substrate_name: NADP+


substrate_name: D-glucose 6-phosphate


substrate_name: allopregnanolone


substrate_name: geranylgeraniol


substrate_name: Cyclohexanol


substrate_name: dehydroepiandrosterone


substrate_name: farnesol


substrate_name: beta-ionol


enzyme_display_name: D-galactose 1-dehydrogenase

organism: Azotobacter vinelandii

substrate_name: NAD+


substrate_name: D-galactose


organism: Digitalis purpurea


substrate_name: NADH


substrate_name: D-glucose


substrate_name: deamino-NADP+


substrate_name: D-galactose 6-phosphate


substrate_name: Unknown


organism: Coriandrum sativum


organism: Cavia porcellus

substrate_name: testosterone


enzyme_display_name: glucose 1-dehydrogenase

organism: Lagothrix lagotricha

substrate_name: beta-D-Glucose; NAD+


organism: Homo sapiens


substrate_name: NADP+


enzyme_display_name: L-arabinose 1-dehydrogenase

organism: Haloferax volcanii


organism: Paralabrax clathratus


organism: Scomber scombrus

substrate_name: NAD+; beta-D-Glucose


substrate_name: NADP+; D-Glucose


organism: Pituophis catenifer


organism: Salmo salar


organism: Roseateles saccharophilus


organism: Sus scrofa

substrate_name: NADPH


organism: Alburnus tarichi


organism: Canis lupus familiaris


organism: Gallus gallus


organism: Rattus norvegicus

substrate_name: pregnenolone


organism: Ictalurus punctatus


organism: [Clostridium] innocuum


enzyme_display_name: 3alpha-hydroxycholanate dehydrogenase

organism: Clostridium perfringens


organism: Bifidobacterium sp.


organism: Pseudomonas sp. B-0831

substrate_name: cholate


substrate_name: dehydrocholate


enzyme_display_name: Aldo-keto reductase family 1 member C2

organism: Homo sapiens

substrate_name: (s)-tetralol (oxidation)


substrate_name: benzene dihydrodiol (oxidation)


substrate_name: prostaglandin D2 (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member C1

substrate_name: (s)-tetralol


organism: Zymomonas mobilis subsp. mobilis


substrate_name: D-glucose 6-phosphate


organism: Mus musculus


organism: Digitalis lanata


substrate_name: NAD+


substrate_name: NADH


organism: Comamonas testosteroni

substrate_name: androsterone


enzyme_display_name: Aldo-keto reductase family 1 member C4


substrate_name: progesterone (reduction)


substrate_name: testosterone (oxidation)


substrate_name: Cyclohexanol


substrate_name: androstenol


organism: Thermoproteus tenax

substrate_name: beta-D-glucose


substrate_name: NADP+


substrate_name: xylose


organism: Thermotoga maritima


substrate_name: 2-deoxy-D-glucose 6-phosphate


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase

organism: Gluconobacter oxydans (strain 621H)

substrate_name: glucose 6-phosphate


substrate_name: NADP(+)


substrate_name: NAD(+)


enzyme_display_name: L-iditol 2-dehydrogenase

substrate_name: xylitol (at pH 10.0)


substrate_name: L-threitol (at pH 10.0)


substrate_name: (2R,3R)-2,3-butanediol (at pH 10.0)


organism: Bos taurus

substrate_name: NADH (at pH 7.4)


substrate_name: 3-pyridinealdehyde adenine dinucleotide


substrate_name: NAD+


substrate_name: Thionicotinamide adenine dinucleotide


substrate_name: 3-acetylpyridine adenine dinucleotide


organism: Macaca fuscata fuscata


organism: Priestia megaterium

substrate_name: NAD(+) (at pH 8.0 and 25 degrees Celsius)


substrate_name: D-glucose (at pH 8.0 and 25 degrees Celsius)


substrate_name: NADP(+) (at pH 8.0 and 25 degrees Celsius)


organism: Taenia crassiceps

substrate_name: D-glucose 6-phosphate


substrate_name: NADP+


substrate_name: NADPH


substrate_name: allopregnanolone (oxidation)


organism: Koliella antarctica


organism: Rattus norvegicus

substrate_name: Dehydrolithocholic acid


substrate_name: diacetyl


substrate_name: isatin


organism: Drosophila melanogaster


organism: Meyerozyma guilliermondii


enzyme_display_name: Glucose 1-dehydrogenase 4


enzyme_display_name: Glucose 1-dehydrogenase 1


enzyme_display_name: Glucose 1-dehydrogenase 3


enzyme_display_name: Glucose 1-dehydrogenase 2


substrate_name: NADP(+) (at pH 8.0)


organism: Pseudomonas sp. B-0831

substrate_name: cholate


substrate_name: dehydrocholate


enzyme_display_name: mannitol-1-phosphate 5-dehydrogenase

organism: Acinetobacter baumannii


substrate_name: NADH


substrate_name: androsterone


substrate_name: NAD+


substrate_name: 2-deoxy-D-glucose 6-phosphate


substrate_name: glucose (at pH 6.0 and 37 degrees Celsius)


enzyme_display_name: UniProt P39485

substrate_name: D-glucose


enzyme_display_name: Name not preserved

organism: Trypanosoma cruzi


organism: Aspergillus aculeatus


enzyme_display_name: Glucose 1-dehydrogenase

substrate_name: NADP(+) (at pH 8.0 and 25 degrees Celsius)


substrate_name: NAD(+) (at pH 8.0 and 25 degrees Celsius)


substrate_name: D-glucose 6-phosphate


substrate_name: NADP+


organism: Digitalis lanata


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)+]

organism: Thermoplasma acidophilum


substrate_name: beta-D-glucose


organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

substrate_name: glucose


substrate_name: NADP(+)


organism: Eggerthella lenta


substrate_name: cholic acid


organism: Comamonas testosteroni


substrate_name: 3-pyridinealdehyde adenine dinucleotide


substrate_name: (s)-tetralol


organism: Homo sapiens

substrate_name: xylitol (at pH 10.0)


substrate_name: L-threitol (at pH 10.0)


substrate_name: (2R,3R)-2,3-butanediol (at pH 10.0)


organism: Bos taurus

substrate_name: NADH (at pH 7.4)


substrate_name: D-fructose (at pH 7.4)


enzyme_display_name: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

organism: Arabidopsis thaliana

substrate_name: pyruvate


substrate_name: (S)-malate


enzyme_display_name: UniProt P93819

substrate_name: oxaloacetate


substrate_name: NADH


substrate_name: (s)-indan-1-ol (oxidation)


substrate_name: 5alpha-androstan-3,17-dione (reduction)


enzyme_display_name: L-xylulose reductase

organism: Trichoderma reesei

substrate_name: NADPH


organism: Ascaris suum

substrate_name: L-malate


substrate_name: NADP+


enzyme_display_name: malate dehydrogenase (decarboxylating)


substrate_name: NAD+


organism: Halobacterium salinarum

substrate_name: beta-D-glucose


enzyme_display_name: UniProt Q8GQE7

organism: Burkholderia cepacia


substrate_name: NADP(+)


organism: Taenia crassiceps

substrate_name: D-glucose 6-phosphate


enzyme_display_name: UniProt P11413


substrate_name: NADP


substrate_name: xylitol (at pH 10.0)


substrate_name: L-threitol (at pH 10.0)


substrate_name: (2R,3R)-2,3-butanediol (at pH 10.0)


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase

organism: Gluconobacter oxydans (strain 621H)

substrate_name: NAD(+)


organism: Rattus norvegicus

substrate_name: androsterone


substrate_name: glycolithocholic acid


enzyme_display_name: Aldo-keto reductase family 1 member C2


substrate_name: progesterone (reduction)


enzyme_display_name: 3-beta-hydroxysteroid dehydrogenase

organism: Mycolicibacterium neoaurum

substrate_name: testosterone


enzyme_display_name: L-iditol 2-dehydrogenase

substrate_name: D-ribulose (at pH 7.4)


enzyme_display_name: 3alpha-hydroxysteroid dehydrogenase

organism: Eggerthella lenta (strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC 3265 / NCTC 11813 / VPI 0255 / 1899 B)

substrate_name: deoxycholate


enzyme_display_name: L-gulonate 3-dehydrogenase

organism: Drosophila melanogaster

substrate_name: L-gulonate


organism: Leuconostoc mesenteroides

substrate_name: NADP+


substrate_name: glucose 6-phosphate


substrate_name: NAD+


organism: Mesocricetus auratus


substrate_name: dehydroepiandrosterone


substrate_name: farnesol


substrate_name: geraniol


substrate_name: geranylgeraniol


substrate_name: nerol


substrate_name: beta-ionol


substrate_name: cis-benzene dihydrodiol


substrate_name: Cyclohexanol


substrate_name: Isatin


enzyme_display_name: TBER1 / novel rat cytoplasmic 17beta-hydroxysteroid dehydrogenase

substrate_name: 9alpha,11beta-Prostaglandin F2


substrate_name: Dimethylglyoxal


substrate_name: p-Nitrobenzaldehyde


substrate_name: chenodeoxycholate


substrate_name: Benzene dihydrodiol


substrate_name: Camphorquinone


substrate_name: m-Nitrobenzaldehyde


substrate_name: trans-benzene dihydrodiol


substrate_name: testosterone


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 17beta-hydroxy-5alpha-androstan-3-one (5-alpha-dihydrotestosterone) (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: 17-beta-estradiol (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 5alpha-pregnan-20beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate (also known as isoursodeoxycholate or 7beta-hydroxyisolithocholate) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NAD (in the presence of aldosterone, at pH 9.3 and 25 degrees Celsius)


organism: Trypanosoma cruzi

substrate_name: D-glucose 6-phosphate


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)(+)]

organism: Sulfolobus solfataricus

substrate_name: D-Xylose


substrate_name: D-Galactose


substrate_name: D-Glucose


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


enzyme_display_name: GDH/6PGL endoplasmic bifunctional protein

organism: Mus musculus

substrate_name: D-glucose (at pH 7.1 in the presence of NAD)


substrate_name: D-glucose 6-phosphate (at pH 9.6 in the presence of NADP)


substrate_name: 2-deoxy-D-glucose 6-phosphate (at pH 7.1 in the presence of NADP)


substrate_name: D-galactopyranose 6-phosphate (at pH 7.1 in the presence of NADP)


substrate_name: NADP (at pH 7.1 in the presence of galactose 6-phosphate)


substrate_name: NAD (at pH 7.1 in the presence of D-glucose)


organism: Priestia megaterium

substrate_name: D-glucose


organism: Bacillus megaterium


substrate_name: NADP+


organism: Comamonas testosteroni

substrate_name: Fusidic acid


substrate_name: cholic acid


substrate_name: androstanedione


substrate_name: metyrapone


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase 1, chloroplastic

organism: Arabidopsis thaliana

substrate_name: NADP


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase 3, chloroplastic


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase 6, cytoplasmic


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase 2, chloroplastic


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase 5, cytoplasmic


organism: Homo sapiens


enzyme_display_name: Galactose 1-dehydrogenase

organism: Pseudomonas fluorescens

substrate_name: NAD(+)


substrate_name: NADP(+)


substrate_name: D-galactose


substrate_name: NAD+


organism: Aspergillus nidulans

substrate_name: NADPH


substrate_name: D-glucose 6-phosphate


organism: Escherichia coli

substrate_name: D-Glucose 6-phosphate


substrate_name: glucose 6-phosphate


organism: Pseudomonas sp

substrate_name: androsterone


substrate_name: fusidic acid


substrate_name: (3S)-3-hydroxybutanoyl-CoA (beta-hydroxybutyryl-CoA) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: Lambda-crystallin homolog

substrate_name: NAD


substrate_name: NADH


enzyme_display_name: Lambda-crystallin

organism: Oryctolagus cuniculus


substrate_name: D-Galactose


substrate_name: D-Glucose


enzyme_display_name: Glucose 1-dehydrogenase

organism: Saccharolobus solfataricus

substrate_name: NAD(+) (at 70 degrees Celsius and pH 8)


substrate_name: NADP(+) (at 70 degrees Celsius and pH 8)


substrate_name: NADP+


organism: Drosophila melanogaster

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)+]

organism: Halobacterium salinarum


organism: Mesocricetus auratus

substrate_name: NAD+


organism: Trypanosoma cruzi


organism: Rattus norvegicus

substrate_name: NADPH


organism: Neurospora crassa


substrate_name: D-glucose 6-phosphate


enzyme_display_name: L-arabinose 1-dehydrogenase (NAD(P)(+))

organism: Azospirillum brasilense

substrate_name: NADP(+) (at 30 degrees Celsius and pH 9.0)


substrate_name: NAD(+) (at 30 degrees Celsius and pH 9.0)


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: glucose-6-phosphate (at 25 degrees Celsius)


substrate_name: NADP(+) (at 25 degrees Celsius)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 1


substrate_name: estrone


organism: Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1)

substrate_name: NADP(+) (at 70 degrees Celsius and pH 7)


substrate_name: beta-D-glucose


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase

substrate_name: glucose 6-phosphate


substrate_name: testosterone


organism: Priestia megaterium


organism: Homo sapiens

substrate_name: NAADP


substrate_name: D-glucose


substrate_name: D-xylose


substrate_name: beta-D-galactose


enzyme_display_name: L-gulonate 3-dehydrogenase


substrate_name: L-gulonate


substrate_name: NAD+


substrate_name: NADP+


substrate_name: NADH


substrate_name: L-threonate


substrate_name: acetoacetate


organism: Sus scrofa


substrate_name: beta-keto-L-gulonate


substrate_name: L-Idonate


organism: Corynebacterium sp.


substrate_name: gentiobiose


substrate_name: cellobiose


substrate_name: D-glucose 6-phosphate


substrate_name: 2-deoxy-D-glucose 6-phosphate


substrate_name: deamino-NADP+


substrate_name: Unknown


substrate_name: D-glucose


substrate_name: dihydrotestosterone


substrate_name: testosterone


substrate_name: estradiol


organism: Canis lupus familiaris


organism: Bacillus amyloliquefaciens


substrate_name: NAD+


substrate_name: NADP+


organism: Lysinibacillus sphaericus


substrate_name: beta-D-glucose


organism: Bacillus thuringiensis serovar kurstaki


organism: Bacillus subtilis


substrate_name: D-glucosamine


organism: Bos taurus


organism: Bacillus sp. (in: firmicutes)


organism: Ovis aries


organism: Arabidopsis thaliana


organism: Nicotiana tabacum


enzyme_display_name: isocitrate dehydrogenase (NADP+)

organism: Staphylococcus aureus

substrate_name: isocitrate


substrate_name: D-isocitrate


substrate_name: D,L-isocitrate


organism: Trypanosoma cruzi

substrate_name: DL-isocitrate


organism: Thermus aquaticus


organism: Archaeoglobus fulgidus


organism: Lathyrus oleraceus


enzyme_display_name: phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

organism: Enterococcus faecalis


organism: Klebsiella pneumoniae


organism: Priestia megaterium


organism: Phormidium sp.


organism: Saccharolobus solfataricus


organism: Nostoc sp.


organism: Escherichia coli


organism: Bos taurus


organism: Bacillus subtilis


enzyme_display_name: D-galactose 1-dehydrogenase

organism: Pseudomonas fluorescens

substrate_name: D-galactose


organism: Mus musculus


substrate_name: D-glucose 6-phosphate


organism: Hordeum vulgare


organism: Cavia porcellus


enzyme_display_name: 17beta-estradiol 17-dehydrogenase

organism: Curvularia lunata

substrate_name: NADPH


enzyme_display_name: mannitol 2-dehydrogenase

organism: Tetraselmis subcordiformis

substrate_name: D-mannitol


substrate_name: D-fructose


enzyme_display_name: Aldo-keto reductase family 1 member C3

organism: Homo sapiens


substrate_name: testosterone (oxidation)


organism: Leuconostoc pseudomesenteroides


organism: Rattus norvegicus


substrate_name: Dimethylglyoxal


substrate_name: NADH


substrate_name: p-Nitrobenzaldehyde


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

organism: Drosophila melanogaster

substrate_name: (3S)-3-hydroxybutanoyl-CoA (beta-hydroxybutyryl-CoA) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 5alpha-pregnan-20beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate (also known as isoursodeoxycholate or 7beta-hydroxyisolithocholate) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NAD (in the presence of aldosterone, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: 4-hydroxybutyrate dehydrogenase

organism: Clostridium kluyveri

substrate_name: succinic semialdehyde


substrate_name: NAD


substrate_name: testosterone


enzyme_display_name: isocitrate dehydrogenase (NAD+)

organism: Saccharomyces cerevisiae

substrate_name: D,L-isocitrate


organism: Aspergillus niger

substrate_name: NADP+


substrate_name: D-glucose 6-phosphate


substrate_name: Unknown


organism: Plasmodium falciparum


enzyme_display_name: estradiol 17beta-dehydrogenase

substrate_name: NADPH; H+; Estrone

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: NAD+


organism: Pseudomonas sp.


organism: Mycobacterium tuberculosis

substrate_name: isocitrate


organism: Bos taurus


organism: Bacillus sp. (in: firmicutes)


enzyme_display_name: pyridoxine 4-dehydrogenase

organism: Schizosaccharomyces pombe

substrate_name: pyridoxal


organism: Sus scrofa


enzyme_display_name: Dehydrogenase/reductase SDR family member 11

substrate_name: 5-alpha-androstan-3-alpha-ol-17-one (at 37 degrees Celsius)


substrate_name: dehydroepiandrosterone (DHEA) (at 37 degrees Celsius)


substrate_name: DHEA sulfate (at 37 degrees Celsius)


substrate_name: dehydrolithocholic acid (at 37 degrees Celsius)


substrate_name: 20-alpha-hydroxyprogesterone (at 37 degrees Celsius)


substrate_name: taurodehydrocholic acid (at 37 degrees Celsius)


substrate_name: dehydrocholic acid (at 37 degrees Celsius)


substrate_name: 5-beta-dihydrotestosterone (DHT) (at 37 degrees Celsius)


substrate_name: Isatin


substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: (3S)-3-hydroxybutanoyl-CoA (beta-hydroxybutyryl-CoA) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 17beta-hydroxy-5alpha-androstan-3-one (5-alpha-dihydrotestosterone) (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: 17-beta-estradiol (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 5alpha-pregnan-20beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate (also known as isoursodeoxycholate or 7beta-hydroxyisolithocholate) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of aldosterone, at pH 9.3 and 25 degrees Celsius)


organism: Aspergillus fumigatus

substrate_name: D-mannitol


substrate_name: D-Xylulose


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Mus musculus

substrate_name: all-trans-retinol


organism: Pseudomonas fluorescens

substrate_name: D-arabitol


organism: Gallus gallus


organism: Homo sapiens


substrate_name: testosterone


substrate_name: androsterone


substrate_name: D-fructose


substrate_name: estrone


organism: Aeropyrum pernix

substrate_name: NADP+


organism: Cavia porcellus


enzyme_display_name: 2-hydroxy-3-oxopropionate reductase

organism: Mycosarcoma maydis


substrate_name: NADH


substrate_name: D-glycerate


substrate_name: L-Glycerate


organism: Pseudomonas putida


organism: Rhodococcus sp. P14


organism: Thermotoga maritima


substrate_name: NAD+


substrate_name: NADPH


organism: Levilactobacillus brevis


organism: Absidia glauca


organism: Curvularia lunata


organism: Leuconostoc mesenteroides


organism: Bradyrhizobium japonicum


organism: Porphyromonas gingivalis

substrate_name: succinate semialdehyde


organism: Tetraselmis subcordiformis


organism: Montipora capitata


organism: Sus scrofa


organism: Fructilactobacillus sanfranciscensis


substrate_name: androstenedione


substrate_name: benzene dihydrodiol


organism: Canis lupus familiaris

substrate_name: Unknown


organism: Thermotoga neapolitana


organism: Homo sapiens

substrate_name: NAD


substrate_name: NADP


substrate_name: all-trans-retinol


substrate_name: allopregnanolone


substrate_name: androsterone


substrate_name: dehydroepiandrosterone


enzyme_display_name: Aldo-keto reductase family 1 member C4


substrate_name: testosterone (oxidation)


enzyme_display_name: Aldo-keto reductase family 1 member C1

substrate_name: progesterone (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member C2


substrate_name: (s)-tetralol


substrate_name: (s)-tetralol (oxidation)


substrate_name: benzene dihydrodiol (oxidation)


substrate_name: prostaglandin D2 (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member B15

substrate_name: all-trans-retinal


substrate_name: D,L-glyceraldehyde


substrate_name: hexanal


substrate_name: acrolein


substrate_name: farnesal


substrate_name: NADPH


organism: Rattus norvegicus


substrate_name: dihydrotestosterone


substrate_name: testosterone


substrate_name: estradiol


substrate_name: NAD


substrate_name: NADP


enzyme_display_name: UniProt O93874


substrate_name: NADP+


substrate_name: NAD+


substrate_name: NADH


organism: Aspergillus fumigatus

substrate_name: L-sorbitol


substrate_name: D-xylulose


substrate_name: D-fructose


substrate_name: D-arabinitol


organism: Escherichia coli

substrate_name: Succinic semialdehyde


substrate_name: methylglyoxal


substrate_name: gamma-hydroxybutyrate


substrate_name: androsterone (tested with isoform 1 in the reductive reaction)


substrate_name: delta-4-androstenedione (tested with isoform 1 in the reductive reaction)


substrate_name: estrone (tested with isoform 1 in the reductive reaction)


substrate_name: acetoacetyl-CoA (tested with isoform 1 in the reductive reaction)


substrate_name: testosterone (tested with isoform 1 in the oxidative reaction)


substrate_name: 17-beta-estradiol (tested with isoform 1 in the oxidative reaction)


substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 7.0 and 25 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: isoursodeoxycholic acid (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: dehydrocorticosterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of beta-hydroxybutyryl-CoA, at pH 9.3 and 25 degrees Celsius)


substrate_name: testosterone (oxidation)


organism: Macaca fuscata fuscata


substrate_name: NADPH


substrate_name: NADP(+)


substrate_name: allopregnanolone (oxidation)


enzyme_display_name: 3-sulfolactaldehyde reductase

organism: Escherichia coli (strain K12)


substrate_name: NADH


organism: Leuconostoc pseudomesenteroides

substrate_name: D-mannitol


substrate_name: D-fructose


organism: Cupriavidus necator


substrate_name: NAD(+)


enzyme_display_name: UniProt Q9BPX1


substrate_name: progesterone


substrate_name: androstanediol


substrate_name: tetramyristoyl cardiolipin


substrate_name: tetralinoleoyl cardiolipin


enzyme_display_name: UniProt P14061

substrate_name: estrone


substrate_name: (s)-indan-1-ol (oxidation)


substrate_name: (s)-tetralol


substrate_name: progesterone (reduction)


substrate_name: 5alpha-androstan-3,17-dione (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member C3

substrate_name: prostaglandin H2


enzyme_display_name: mannitol 2-dehydrogenase

organism: Eimeria tenella


enzyme_display_name: Pyridoxine 4-dehydrogenase


enzyme_display_name: 17beta-estradiol 17-dehydrogenase


organism: Pseudomonas fluorescens

substrate_name: D-Arabitol


substrate_name: 9alpha,11beta-Prostaglandin F2


substrate_name: 5-beta-androstane-3,17-dione (at 37 degrees Celsius)


substrate_name: 4-androstene-3,17-dione (at 37 degrees Celsius)


substrate_name: progesterone (at 37 degrees Celsius)


substrate_name: 5-beta-pregnane-3,20-dione (at 37 degrees Celsius)


substrate_name: 17-beta-estradiol (at 37 degrees Celsius)


substrate_name: testosterone (at 37 degrees Celsius)


substrate_name: 5-alpha-androstane-3-alpha,17-beta-diol (at 37 degrees Celsius)


substrate_name: isolithocholic acid (at 37 degrees Celsius)


substrate_name: 1-phenyl-1,2-propanedione (at 37 degrees Celsius)


substrate_name: 2,3-hexanedione (at 37 degrees Celsius)


substrate_name: Dimethylglyoxal


substrate_name: Isatin


substrate_name: NAD+


substrate_name: NADH


substrate_name: NADPH


substrate_name: p-Nitrobenzaldehyde


substrate_name: 2,3-heptanedione (at 37 degrees Celsius)


substrate_name: 3,4-hexanedione (at 37 degrees Celsius)


substrate_name: alpha-tetralone (at 37 degrees Celsius)


substrate_name: loxoprofen (at 37 degrees Celsius)


substrate_name: estrone (at 37 degrees Celsius)


substrate_name: 5-alpha-androstan-3-alpha-ol-17-one (at 37 degrees Celsius)


substrate_name: dehydroepiandrosterone (DHEA) (at 37 degrees Celsius)


substrate_name: DHEA sulfate (at 37 degrees Celsius)


substrate_name: dehydrolithocholic acid (at 37 degrees Celsius)


substrate_name: 20-alpha-hydroxyprogesterone (at 37 degrees Celsius)


substrate_name: taurodehydrocholic acid (at 37 degrees Celsius)


substrate_name: dehydrocholic acid (at 37 degrees Celsius)


substrate_name: 5-beta-dihydrotestosterone (DHT) (at 37 degrees Celsius)


substrate_name: meso-erythritol


substrate_name: D-Arabitol


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

organism: Drosophila melanogaster

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: (3S)-3-hydroxybutanoyl-CoA (beta-hydroxybutyryl-CoA) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 17beta-hydroxy-5alpha-androstan-3-one (5-alpha-dihydrotestosterone) (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: 17-beta-estradiol (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 5alpha-pregnan-20beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate (also known as isoursodeoxycholate or 7beta-hydroxyisolithocholate) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of aldosterone, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 2

substrate_name: estradiol


substrate_name: testosterone


substrate_name: dihydrotestosterone


substrate_name: androstenedione


substrate_name: estrone


substrate_name: 5alpha-androstane 3alpha,17beta-diol


substrate_name: androsterone


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH7

substrate_name: 10-OH-decanoic acid (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: hexanol (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: hexanal (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 2-hexenol (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 2-hexenal (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 4-hydroxynonenal (with 0.1 M sodium phosphate at pH 7.5)


enzyme_display_name: pyridoxine 4-dehydrogenase

organism: Schizosaccharomyces pombe


substrate_name: p-Nitrobenzaldehyde


substrate_name: Pyridoxal


substrate_name: all-trans-retinol


substrate_name: all-trans-retinal


enzyme_display_name: 4-hydroxybutyrate dehydrogenase

organism: Clostridium kluyveri


substrate_name: NADH


substrate_name: succinate semialdehyde


substrate_name: NAD+


substrate_name: D-arabinitol


substrate_name: D-fructose


substrate_name: D-mannitol


substrate_name: D-Xylulose


substrate_name: L-Sorbitol


organism: Bos taurus

substrate_name: prostaglandin D2


substrate_name: menadione


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Mus musculus


substrate_name: androsterone


substrate_name: estradiol


substrate_name: D-Arabitol


substrate_name: meso-erythritol


enzyme_display_name: (3R)-3-hydroxyacyl-CoA dehydrogenase


substrate_name: testosterone


substrate_name: estrone


substrate_name: dihydrotestosterone


organism: Saccharomyces cerevisiae

substrate_name: NADPH


substrate_name: NADP+


substrate_name: pyridoxal


substrate_name: pyridoxol


enzyme_display_name: 2-hydroxy-3-oxopropionate reductase

organism: Haemophilus influenzae

substrate_name: (R)-beta-hydroxybutyrate


substrate_name: D-threonine


substrate_name: D-glycerate


organism: Homo sapiens

substrate_name: NAD


substrate_name: NADP


enzyme_display_name: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7


organism: Hyphomicrobium sp.

substrate_name: tartronate semialdehyde


organism: Aspergillus fumigatus

substrate_name: NAD+


substrate_name: NADH


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 1


enzyme_display_name: Very-long-chain 3-oxoacyl-CoA reductase


organism: Rattus norvegicus


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase 13


substrate_name: prostaglandin D2


substrate_name: menadione


substrate_name: androstenedione


enzyme_display_name: Pyridoxal reductase

organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)


enzyme_display_name: Mannitol dehydrogenase DSF1

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: mannitol


enzyme_display_name: mannitol 2-dehydrogenase

substrate_name: D-mannitol


substrate_name: meso-erythritol


substrate_name: D-arabitol


substrate_name: D-Mannitol


substrate_name: polyethylenimine-NH-succinyl-NADH


substrate_name: D-fructose


enzyme_display_name: omega-hydroxydecanoate dehydrogenase

organism: Sus scrofa


organism: Pseudomonas putida

substrate_name: NADPH


substrate_name: D-glycerate


organism: Cupriavidus necator


substrate_name: Unknown


enzyme_display_name: 17beta-estradiol 17-dehydrogenase

substrate_name: equilin


substrate_name: equilenin


substrate_name: estradiol 3-methyl ether


substrate_name: NADH


substrate_name: malonic semialdehyde


organism: Oryctolagus cuniculus

substrate_name: estradiol


substrate_name: NAD+


substrate_name: NADP+


substrate_name: dehydroepiandrosterone


substrate_name: estrone


substrate_name: dihydrotestosterone


substrate_name: androstenedione


organism: Escherichia coli


substrate_name: L-Glycerate


enzyme_display_name: estradiol 17beta-dehydrogenase

substrate_name: NADPH; H+; Estrone


substrate_name: NADPH


substrate_name: benzene diohydrodiol


substrate_name: testosterone


substrate_name: benzene dihydrodiol


organism: Pseudomonas fluorescens

substrate_name: NAD(P)H


substrate_name: allopregnanolone


enzyme_display_name: isocitrate dehydrogenase (NADP+)

substrate_name: Unknown


organism: Gallus gallus


substrate_name: NADH


enzyme_display_name: phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)


organism: Spinacia oleracea


substrate_name: NADP+; 6-Phospho-D-gluconate


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)+]

organism: Saccharolobus solfataricus

substrate_name: beta-D-glucose


organism: Burkholderia cepacia


organism: Bacillus subtilis

substrate_name: NAD+


substrate_name: beta-D-xylose


organism: Ovis aries


enzyme_display_name: D-galactose 1-dehydrogenase


substrate_name: L-arabinose


organism: Homo sapiens

substrate_name: 2-deoxyglucose 6-phosphate


organism: Priestia megaterium


substrate_name: NADP+


organism: Aquifex aeolicus

substrate_name: D-glucose 6-phosphate


organism: Oncorhynchus mykiss


organism: Camelus dromedarius


organism: Hordeum vulgare


organism: Equus caballus


substrate_name: dehydroepiandrosterone


organism: Bos taurus


substrate_name: estrone


organism: Pseudomonas sp.

substrate_name: D-mannitol


organism: Saccharomyces cerevisiae


organism: Cereibacter sphaeroides

substrate_name: D-arabitol


enzyme_display_name: isocitrate dehydrogenase (NAD+)

organism: Rhodomicrobium vannielii

substrate_name: Isocitrate; NAD+


organism: Hydrogenobacter thermophilus

substrate_name: NAD+; Isocitrate


organism: Escherichia coli


organism: Bifidobacterium longum


organism: Ostreococcus tauri


organism: Phaeodactylum tricornutum


enzyme_display_name: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

organism: Homo sapiens


organism: Sus scrofa

substrate_name: Isocitrate; NADP+

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Rattus norvegicus


substrate_name: NADP+; Isocitrate


organism: Pisum sativum


organism: Bacillus subtilis


organism: Halobacterium volcanii


organism: Aspergillus nidulans

substrate_name: D-Isocitrate; NADP+


organism: Thermus thermophilus

substrate_name: Homoisocitrate; NAD+


organism: Mycobacterium tuberculosis


organism: Saccharopolyspora erythraea

substrate_name: DL-isocitrate


organism: Synechocystis sp.

substrate_name: D,L-isocitrate


organism: Chlamydomonas reinhardtii


organism: Caldococcus noboribetus


organism: Mycolicibacterium phlei


enzyme_display_name: UniProt O29610

organism: Archaeoglobus fulgidus


enzyme_display_name: UniProt Q4E4L7

organism: Trypanosoma cruzi


enzyme_display_name: Isocitrate dehydrogenase [NADP], mitochondrial

substrate_name: Unknown


enzyme_display_name: Isocitrate dehydrogenase [NADP] 2

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: D,L-isocitrate (in the presence of Mg(2+))


enzyme_display_name: Isocitrate dehydrogenase [NADP]

organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)


organism: Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)

substrate_name: D,L-isocitrate (in the presence of Mn(2+))


organism: Enterococcus faecalis

substrate_name: 6-Phospho-D-gluconate; NADP+


organism: Lactococcus lactis subsp. cremoris


organism: Homo sapiens

substrate_name: NADP+; 6-Phospho-D-gluconate


organism: Rattus norvegicus


organism: Dicentrarchus labrax


organism: Ovis aries

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Corynebacterium glutamicum


organism: Haemophilus influenzae


organism: Saccharomyces cerevisiae


organism: Spinacia oleracea


organism: Klebsiella pneumoniae


organism: Escherichia coli


organism: Synechocystis sp.


organism: Moorella thermoacetica


organism: Thermotoga maritima


organism: Trypanosoma brucei


organism: Ctenopharyngodon idella


enzyme_display_name: L-gulonate 3-dehydrogenase

organism: Oryctolagus cuniculus

substrate_name: NAD+; L-Gulonate


organism: Drosophila melanogaster


enzyme_display_name: glucose 1-dehydrogenase

organism: Homo sapiens

substrate_name: beta-D-Glucose; NAD+


organism: Mus musculus


organism: Columba sp.


organism: Gallus gallus


organism: Bacillus megaterium

substrate_name: D-Glucose; NAD+


substrate_name: NAD+; D-Glucose


organism: Rattus norvegicus

substrate_name: NADP+; Glucose 6-phosphate


organism: Sulfolobus solfataricus

substrate_name: D-Glucose; NADP+


organism: Bacillus subtilis


enzyme_display_name: Glucose 1-dehydrogenase

organism: Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1)

substrate_name: glucose (in the presence of NADP(+), at 70 degrees Celsius and pH 7)


organism: Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4)

substrate_name: beta-D-glucose (in the presence of NADP(+), at 40 degrees Celsius and pH 8.8)


enzyme_display_name: galactose 1-dehydrogenase

substrate_name: D-Galactose 6-phosphate; NADP+


enzyme_display_name: L-arabinose 1-dehydrogenase (NAD(P)(+))

organism: Azospirillum brasilense

substrate_name: L-arabinose (in the presence of NAD(+), at 30 degrees Celsius and pH 9.0)


organism: Saccharolobus solfataricus

substrate_name: D-glucose (in the presence of NAD(+), at 70 degrees Celsius and pH 8)


organism: Thermotoga maritima

substrate_name: thio-NAD+


organism: Taenia crassiceps

substrate_name: Unknown


organism: Aspergillus aculeatus


organism: Brugia malayi


substrate_name: 2-Deoxy-D-glucose 6-phosphate


substrate_name: NAD+


substrate_name: NADP+


substrate_name: thio-NADP+


substrate_name: glucose 6-phosphate


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: 6-phosphoglucono-gamma-lactone (at 25 degrees Celsius)


enzyme_display_name: Glucose-6-phosphate 1-dehydrogenase

organism: Gluconobacter oxydans (strain 621H)


organism: Comamonas testosteroni

substrate_name: NADH


substrate_name: androstandione


organism: Pseudomonas sp


enzyme_display_name: Aldo-keto reductase family 1 member C4

organism: Homo sapiens


enzyme_display_name: Aldo-keto reductase family 1 member C2


enzyme_display_name: Aldo-keto reductase family 1 member C1


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

organism: Drosophila melanogaster

substrate_name: NAD (in the presence of (3S)-3-hydroxybutanoyl-CoA, at pH 9.3 and 25 degrees Celsius)


organism: Macaca fuscata fuscata


enzyme_display_name: 2-hydroxy-3-oxopropionate reductase

organism: Escherichia coli

substrate_name: NADH; 2-Hydroxy-3-oxopropanoate; H+


substrate_name: NAD+; D-Glycerate


organism: Haemophilus influenzae

substrate_name: D-Glycerate; NAD+


enzyme_display_name: 4-hydroxybutyrate dehydrogenase

substrate_name: 3-hydroxypropane sulfonate


enzyme_display_name: estradiol 17beta-dehydrogenase

organism: Rattus norvegicus


substrate_name: Estrone; H+; NADPH


substrate_name: H+; NADPH; Estrone


organism: Mus musculus

substrate_name: Estradiol-17beta; NAD+


substrate_name: NAD+; Estradiol-17beta


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

substrate_name: Unknown


substrate_name: 5-alpha-pregnan-20-beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase 13


enzyme_display_name: Dehydrogenase/reductase SDR family member 11

substrate_name: 5-alpha-androstan-3-beta-ol-17-one (at 37 degrees Celsius)


enzyme_display_name: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7


substrate_name: NADP+; Testosterone


substrate_name: Testosterone; NADP+


substrate_name: NADPH; H+; Androst-4-ene-3,17-dione


enzyme_display_name: Aldo-keto reductase family 1 member B15

substrate_name: 3-alpha,17-beta-androstandiol (tested with isoform 1 in the oxidative reaction)


enzyme_display_name: pyridoxine 4-dehydrogenase

organism: Schizosaccharomyces pombe

substrate_name: Pyridoxal; H+; NADPH


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH7

substrate_name: 12-OH-dodecanoic acid (with 0.1 M sodium phosphate at pH 7.5)


enzyme_display_name: mannitol 2-dehydrogenase

organism: Pseudomonas fluorescens

substrate_name: NADH; H+; D-Fructose


organism: Aspergillus fumigatus

substrate_name: D-Mannitol; NAD+


enzyme_display_name: Mannitol dehydrogenase DSF1

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


enzyme_display_name: isocitrate dehydrogenase (NAD+)

organism: Phycomyces blakesleeanus

substrate_name: NAD+; Isocitrate


enzyme_display_name: isocitrate dehydrogenase (NADP+)

organism: Streptococcus suis

substrate_name: Isocitrate; NADP+


enzyme_display_name: glucose 1-dehydrogenase

organism: Bos taurus

substrate_name: NAD+; beta-D-Glucose


organism: Sus scrofa

substrate_name: beta-D-Glucose; NAD+


organism: Gallus gallus

substrate_name: NADP+; Estradiol-17beta


enzyme_display_name: 3-hydroxypropionate dehydrogenase

organism: Bacillus cereus


substrate_name: NADP+


substrate_name: NAD+


enzyme_display_name: allyl-alcohol dehydrogenase


substrate_name: allyl-alcohol


organism: Candida albicans


substrate_name: L-serine


substrate_name: NAD+; 3-Hydroxypropanoate


enzyme_display_name: lactaldehyde reductase (NADPH)

substrate_name: H+; Lactaldehyde; NADPH


substrate_name: L-lactaldehyde


enzyme_display_name: ribitol 2-dehydrogenase

organism: Gluconobacter oxydans

substrate_name: NADH


substrate_name: D-ribulose


substrate_name: ribitol


organism: Pseudomonas putida


substrate_name: benzyl alcohol


substrate_name: 3-aminobenzyl alcohol


substrate_name: (R)-(+)-perillyl alcohol


substrate_name: cinnamyl alcohol


organism: Sphingomonas sp.


substrate_name: D-ribitol


organism: Nicotiana tabacum

substrate_name: (S)-pulegone


organism: Homo sapiens

substrate_name: NAD


substrate_name: NADPH


substrate_name: NADP


substrate_name: all-trans-retinol


substrate_name: allopregnanolone


substrate_name: androsterone


substrate_name: dehydroepiandrosterone


organism: Providencia alcalifaciens

substrate_name: NAD+


substrate_name: all-trans-retinal


substrate_name: D,L-glyceraldehyde


substrate_name: hexanal


substrate_name: acrolein


substrate_name: farnesal


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 7.0 and 25 degrees Celsius)


substrate_name: beta-hydroxybutyryl-CoA (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: isoursodeoxycholic acid (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: dehydrocorticosterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of beta-hydroxybutyryl-CoA, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Rattus norvegicus


substrate_name: dihydrotestosterone


substrate_name: testosterone


substrate_name: estradiol


substrate_name: NAD


substrate_name: NADP


organism: Agathobaculum desmolans

substrate_name: cortisone


substrate_name: androsterone (tested with isoform 1 in the reductive reaction)


substrate_name: delta-4-androstenedione (tested with isoform 1 in the reductive reaction)


substrate_name: estrone (tested with isoform 1 in the reductive reaction)


substrate_name: acetoacetyl-CoA (tested with isoform 1 in the reductive reaction)


substrate_name: testosterone (tested with isoform 1 in the oxidative reaction)


substrate_name: 17-beta-estradiol (tested with isoform 1 in the oxidative reaction)


enzyme_display_name: Aldo-keto reductase family 1 member C1

substrate_name: (s)-tetralol


enzyme_display_name: Aldo-keto reductase family 1 member C4


enzyme_display_name: Aldo-keto reductase family 1 member C3


substrate_name: testosterone (oxidation)


substrate_name: progesterone (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member B1

substrate_name: acrolein


substrate_name: D,L-glyceraldehyde


substrate_name: glucose


substrate_name: all-trans-retinal


enzyme_display_name: Aldo-keto reductase family 1 member B10


organism: Mus musculus


enzyme_display_name: Aldo-keto reductase family 1 member A1

substrate_name: D,L glyceraldehyde


substrate_name: D-glucuronic acid


substrate_name: methylglyoxal


substrate_name: D-glucurono-gamma-lactone


substrate_name: D-xylose


substrate_name: D-glucose


substrate_name: D-glucuronate


enzyme_display_name: gluconate 5-dehydrogenase

substrate_name: NADPH


substrate_name: NADP+


substrate_name: D-gluconate


enzyme_display_name: Sorbitol dehydrogenase

substrate_name: xylitol (at pH 10.0)


substrate_name: L-threitol (at pH 10.0)


substrate_name: (2R,3R)-2,3-butanediol (at pH 10.0)


substrate_name: D-fructose (at pH 7.1)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: androsterone


substrate_name: progesterone


enzyme_display_name: alcohol dehydrogenase [NAD(P)+]

organism: Saccharomyces cerevisiae

substrate_name: Butanal


substrate_name: ethanol


organism: Acinetobacter calcoaceticus


substrate_name: benzyl alcohol


organism: Pyrococcus horikoshii


substrate_name: NAD+


substrate_name: propanal


substrate_name: pentanal


substrate_name: NADH


organism: Thermococcus sibiricus


substrate_name: Pyruvaldehyde


organism: Acetivibrio thermocellus

substrate_name: acetaldehyde


substrate_name: NADPH


organism: Ralstonia sp.


substrate_name: NADP+


substrate_name: Cyclohexanol


substrate_name: cyclohexanone


substrate_name: benzaldehyde


organism: Haloferax volcanii


organism: Halobacterium salinarum


organism: Thermococcus kodakarensis


substrate_name: acetoin


organism: Solanum tuberosum


substrate_name: hexanal


substrate_name: Salicylaldehyde


organism: Leuconostoc mesenteroides


enzyme_display_name: glycerol dehydrogenase (NADP+)


substrate_name: D-glyceraldehyde


substrate_name: glycerol


organism: Neurospora crassa


organism: Cucumis melo


organism: Gluconacetobacter liquefaciens


substrate_name: D-gluconate


organism: Halobacterium sp.


substrate_name: ethanol


organism: Gluconobacter oxydans


substrate_name: L-arabitol


substrate_name: D-xylose


organism: Oryctolagus cuniculus

substrate_name: H+; D-Glyceraldehyde; NADPH


organism: Haloarcula marismortui


enzyme_display_name: octanol dehydrogenase

organism: Saccharomyces cerevisiae

substrate_name: NAD+


enzyme_display_name: (R)-aminopropanol dehydrogenase

organism: Bacillus subtilis


organism: Moniezia expansa


substrate_name: methylglyoxal


organism: Clostridium beijerinckii

substrate_name: Butanal


organism: Pseudomonas sp.


substrate_name: NADP+


organism: Lactobacillus delbrueckii


organism: Rattus norvegicus


organism: Lactiplantibacillus plantarum


substrate_name: D-glucuronate


organism: Lactobacillus acidophilus


enzyme_display_name: Carbonyl reductase [NADPH] 1

organism: Sus scrofa

substrate_name: prostaglandin E2


substrate_name: menadione


substrate_name: NADPH


organism: Homo sapiens

substrate_name: all-trans-retinal


substrate_name: all-trans-retinol


substrate_name: NADH


enzyme_display_name: Glycerol dehydrogenase

organism: Escherichia coli (strain K12)

substrate_name: glycerol (at 25 degrees Celsius and pH 7)


substrate_name: dihydroxyacetone (at 25 degrees Celsius and pH 7)


substrate_name: glycolaldehyde (at 25 degrees Celsius and pH 7)


substrate_name: methylglyoxal (at 25 degrees Celsius and pH 7)


substrate_name: S-nitroso-CoA


substrate_name: D,L-glyceraldehyde


enzyme_display_name: ribitol 2-dehydrogenase

organism: Cereibacter sphaeroides

substrate_name: NAD+


substrate_name: D-ribulose


substrate_name: ribitol


organism: Pantoea agglomerans


substrate_name: allitol


substrate_name: sorbitol


substrate_name: NAD(+)


substrate_name: NAD(+) (with DL-1,2-propanediol as substrate)


organism: Gluconobacter oxydans

substrate_name: D-arabitol


substrate_name: D-sorbitol


substrate_name: D-gluconic acid


organism: Macaca fuscata fuscata


substrate_name: (s)-tetralol


organism: Streptomyces exfoliatus

substrate_name: progesterone


substrate_name: NADH


substrate_name: all-trans-retinal


substrate_name: androstanediol


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: tetramyristoyl cardiolipin


substrate_name: tetralinoleoyl cardiolipin


organism: Klebsiella aerogenes

substrate_name: NAD+


organism: Arabidopsis thaliana


enzyme_display_name: malate dehydrogenase (NADP+)

organism: Cicer arietinum

substrate_name: NADPH


substrate_name: NADP+


substrate_name: oxaloacetate


substrate_name: (S)-malate


organism: Danio rerio

substrate_name: cortisone


enzyme_display_name: (S,S)-butanediol dehydrogenase

organism: Klebsiella pneumoniae


enzyme_display_name: glyoxylate reductase (NADP(+))

substrate_name: glyoxylate


organism: Malus domestica


substrate_name: Succinic semialdehyde


enzyme_display_name: hydroxypyruvate reductase


substrate_name: Hydroxypyruvate


substrate_name: phenylpyruvate


organism: Spinacia oleracea

substrate_name: NADPH; Oxaloacetate; H+


substrate_name: Oxaloacetate; NADPH; H+


substrate_name: NADPH; H+; Oxaloacetate


enzyme_display_name: lactaldehyde reductase

organism: Rattus norvegicus

substrate_name: acetaldehyde


substrate_name: ethanol


substrate_name: DL-lactaldehyde


enzyme_display_name: isopropanol dehydrogenase (NADP+)

organism: Trichomonas vaginalis

substrate_name: Butanone


substrate_name: acetone


substrate_name: NADPH


enzyme_display_name: glyoxylate reductase (NADP+)

organism: Neurospora crassa


substrate_name: NADH


organism: Methylotuvimicrobium alcaliphilum


organism: Methylococcus capsulatus


enzyme_display_name: methylglyoxal reductase (NADH)

organism: Capra hircus


substrate_name: Phenylglyoxal


substrate_name: methylglyoxal


organism: Bacillus licheniformis


substrate_name: diacetyl


organism: Bos taurus


substrate_name: D-glycerate


substrate_name: NAD+; Lactaldehyde


substrate_name: NAD+


organism: Methylosinus trichosporium

substrate_name: glyoxylate


organism: Acetobacter aceti

substrate_name: glycolate


organism: Pyrococcus horikoshii OT3


organism: Zea mays

substrate_name: 3-Hydroxypyruvate; H+; NADPH


substrate_name: Hydroxypyruvate


organism: Euglena gracilis


organism: Aspergillus fumigatus


substrate_name: n-butanol


substrate_name: NADP+


organism: Aeropyrum pernix


substrate_name: (S)-malate


organism: Hordeum vulgare


organism: Pseudomonas putida


organism: Thermus thermophilus


substrate_name: oxaloacetate


organism: Mycobacterium sp.

substrate_name: (R,S)-acetoin


organism: Bacillus subtilis


organism: Methanothermobacter thermautotrophicus

substrate_name: NADPH


organism: Pseudomonas aeruginosa


organism: Populus gelrica


substrate_name: 3-Hydroxypyruvate; H+; NADH


organism: Spinacia oleracea


organism: Pyrococcus horikoshii


organism: Sinorhizobium meliloti

substrate_name: pyruvate


organism: Clostridium autoethanogenum

substrate_name: acetone


organism: Escherichia coli

substrate_name: H+; Oxaloacetate; NADH


organism: Bos taurus


organism: Pyrococcus yayanosii


organism: Pyrococcus furiosus


organism: Arabidopsis thaliana


substrate_name: Succinic semialdehyde


organism: Saccharomyces cerevisiae


organism: Corynebacterium glutamicum


substrate_name: NADH


enzyme_display_name: Glyoxylate/hydroxypyruvate reductase A

organism: Escherichia coli (strain K12)

substrate_name: glyoxylate (at 25 degrees Celsius and pH 7)


substrate_name: hydroxypyruvate (at 25 degrees Celsius and pH 7)


enzyme_display_name: Glyoxylate/hydroxypyruvate reductase B

substrate_name: hydroxypyruvate (at pH 7.5)


substrate_name: glyoxylate (at pH 7.5)


enzyme_display_name: UniProt Q92LZ4


substrate_name: glyoxylate


substrate_name: phenylpyruvate


enzyme_display_name: UniProt Q92T34


enzyme_display_name: Aldo-keto reductase family 1 member C3

organism: Homo sapiens

substrate_name: prostaglandin H2


enzyme_display_name: Aldo-keto reductase family 1 member C4


substrate_name: Hydroxypyruvate


organism: Hyphomicrobium methylovorum GM2


enzyme_display_name: Aldo-keto reductase family 1 member C1


enzyme_display_name: UniProt Q9SLN8

organism: Nicotiana tabacum

substrate_name: (R)-pulegone


enzyme_display_name: Aldo-keto reductase family 1 member A1

substrate_name: S-nitroso-glutathione


substrate_name: S-nitroso-CoA


enzyme_display_name: D-mannonate oxidoreductase

organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: D-mannonate


enzyme_display_name: UniProt Q48436

organism: Klebsiella pneumoniae


organism: Paecilomyces sp. 'thermophila'


organism: Rattus norvegicus

substrate_name: mevaldate


organism: Delftia acidovorans


enzyme_display_name: Aldo-keto reductase family 1 member B1


organism: Spinacia oleracea


organism: Streptomyces exfoliatus

substrate_name: cortisone


enzyme_display_name: UniProt F8AEA4


enzyme_display_name: UniProt Q8U3Y2


enzyme_display_name: Hydroxypyruvate reductase

organism: Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33)

substrate_name: hydroxypyruvate


enzyme_display_name: alcohol dehydrogenase [NAD(P)(+)]

organism: Pyrococcus horikoshii

substrate_name: propanal


substrate_name: Butanal


substrate_name: NAD+


substrate_name: NADH


substrate_name: NADPH


substrate_name: pentanal


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

organism: Drosophila melanogaster

substrate_name: acetoacetyl-CoA (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: (3S)-3-hydroxybutanoyl-CoA (beta-hydroxybutyryl-CoA) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: androsterone (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 17beta-hydroxy-5alpha-androstan-3-one (5-alpha-dihydrotestosterone) (in the presence of 0.2 mM NADH, at pH 6.4 and 25 degrees Celsius)


substrate_name: 17-beta-estradiol (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 5alpha-pregnan-20beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate (also known as isoursodeoxycholate or 7beta-hydroxyisolithocholate) (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


substrate_name: NADH (in the presence of acetoacetyl-CoA, at pH 7.0 and 25 degrees Celsius)


substrate_name: NAD (in the presence of aldosterone, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: allopregnanolone


substrate_name: dehydroepiandrosterone


substrate_name: androsterone


substrate_name: dihydrotestosterone


enzyme_display_name: glycerol dehydrogenase (NADP(+))

organism: Trichoderma reesei

substrate_name: Acetoin


substrate_name: D-Glucose


substrate_name: Dihydroxyacetone


substrate_name: Dimethylglyoxal


substrate_name: D-Ribose


substrate_name: D-Xylose


substrate_name: Glyoxal


substrate_name: L-Glyceraldehyde


substrate_name: NADPH


substrate_name: methylglyoxal


organism: Clostridium beijerinckii


substrate_name: isopropanol


substrate_name: acetone


enzyme_display_name: Retinol dehydrogenase 16


substrate_name: NAD


substrate_name: NADP


substrate_name: all-trans-retinol


enzyme_display_name: Alcohol dehydrogenase 1

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: isobutanol


organism: Thermococcus sibiricus


substrate_name: NADP+


substrate_name: Pyruvaldehyde


enzyme_display_name: (S,S)-butanediol dehydrogenase


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Mus musculus


substrate_name: androsterone


substrate_name: estradiol


enzyme_display_name: Aldo-keto reductase family 1 member C3

organism: Bos taurus

substrate_name: prostaglandin D2


substrate_name: menadione


enzyme_display_name: 3-hydroxypropionate dehydrogenase

organism: Candida albicans


substrate_name: L-serine


substrate_name: NAD(+)


substrate_name: ethanol


substrate_name: acetaldehyde


substrate_name: NADH


enzyme_display_name: Carbonyl reductase [NADPH] 1

organism: Homo sapiens

substrate_name: prostaglandin E1


substrate_name: phenylglyoxal


enzyme_display_name: alcohol dehydrogenase


organism: Vitis vinifera

substrate_name: 2-keto-L-gulonate (in presence of NADPH)


substrate_name: hydroxypyruvate (in presence of NADPH)


substrate_name: glyoxylate (in presence of NADPH)


substrate_name: pyruvate (in presence of NADPH)


enzyme_display_name: hydroxypyruvate reductase

organism: Methylococcus capsulatus


substrate_name: glyoxylate


substrate_name: NADPH


organism: Acetivibrio thermocellus


substrate_name: prostaglandin E2


substrate_name: daunorubicin


enzyme_display_name: malate dehydrogenase (NADP(+))

organism: Zea mays

substrate_name: L-Malate


substrate_name: NADP+


substrate_name: oxaloacetate


enzyme_display_name: Tartrate dehydrogenase/decarboxylase

organism: Pseudomonas putida

substrate_name: D-malate


substrate_name: (+)-tartrate


substrate_name: NAD(+) (for D-malate oxidation)


substrate_name: butanal


organism: Rattus norvegicus

substrate_name: menadione


enzyme_display_name: 5-keto-D-gluconate 5-reductase

organism: Escherichia coli (strain K12)


substrate_name: D-gluconate


enzyme_display_name: glyoxylate reductase (NADP+)

organism: Saccharomyces cerevisiae

substrate_name: NADH


substrate_name: Hydroxypyruvate


organism: Delftia acidovorans


organism: Spinacia oleracea


organism: Sorghum bicolor


organism: Streptomyces exfoliatus


enzyme_display_name: glyoxylate reductase (NADP(+))

organism: Arabidopsis thaliana

substrate_name: Glyoxylate


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


organism: Mycobacterium sp.

substrate_name: (R,S)-acetoin


enzyme_display_name: Aldo-keto reductase family 1 member A1

organism: Mus musculus

substrate_name: D-glucuronate


organism: Escherichia coli


organism: Homo sapiens

substrate_name: S-nitrosoglutathione


organism: Pyrococcus furiosus


organism: Pyrococcus yayanosii


enzyme_display_name: L-2,3-butanediol dehydrogenase

organism: Corynebacterium glutamicum

substrate_name: (S)-acetoin (at pH 6.0)


enzyme_display_name: malate dehydrogenase (NADP+)

organism: Sorghum sp.

substrate_name: NADPH


substrate_name: glyoxylate


mutation_signature: recombinant truncated enzyme


organism: Mycobacterium tuberculosis

substrate_name: progesterone


substrate_name: androsterone


enzyme_display_name: 3-isopropylmalate dehydrogenase

organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: 3-isopropylmalate (at pH 8 and 60 degrees Celsius)


enzyme_display_name: ketol-acid reductoisomerase (NADP(+))

organism: Streptococcus pneumoniae


organism: Zea mays

substrate_name: oxaloacetate


substrate_name: NADP+


substrate_name: NAD+


substrate_name: (S)-malate


organism: Streptomyces coelicolor


organism: Streptomyces lividans


substrate_name: pyruvate


enzyme_display_name: aryl-alcohol dehydrogenase

organism: Streptomyces sp.

substrate_name: cinnamyl alcohol


substrate_name: coniferyl alcohol


substrate_name: coniferyl aldehyde


enzyme_display_name: aryl-alcohol dehydrogenase (NADP+)

organism: Solanum tuberosum

substrate_name: p-fluorobenzaldehyde


substrate_name: o-fluorobenzaldehyde


substrate_name: p-methylbenzaldehyde


substrate_name: benzaldehyde


substrate_name: p-chlorobenzaldehyde


substrate_name: m-fluorobenzaldehyde


substrate_name: m-hydroxybenzaldehyde


substrate_name: benzyl alcohol


enzyme_display_name: homoisocitrate dehydrogenase

organism: Thermococcus kodakarensis

substrate_name: homoisocitrate


organism: Acinetobacter calcoaceticus

substrate_name: 4-Hydroxybenzyl alcohol


substrate_name: perillyl alcohol


substrate_name: 4-methoxybenzyl alcohol


substrate_name: 4-Isopropylbenzyl alcohol


substrate_name: 3-Methoxybenzyl alcohol


substrate_name: 3,4-dimethoxybenzyl alcohol


substrate_name: 2-hydroxybenzyl alcohol


substrate_name: 2-Methoxybenzyl alcohol


substrate_name: NADPH


substrate_name: p-Hydroxybenzaldehyde


substrate_name: m-chlorobenzaldehyde


substrate_name: m-bromobenzaldehyde


substrate_name: NADP+


substrate_name: o-chlorobenzaldehyde


substrate_name: m-nitrobenzaldehyde


substrate_name: cinnamic aldehyde


substrate_name: p-bromobenzaldehyde


substrate_name: o-bromobenzaldehyde


organism: Deinococcus radiodurans


substrate_name: homoisocitrate


substrate_name: isocitrate


substrate_name: isopropylmalate


substrate_name: (2R,3S)-3-propylmalic acid


organism: Neurospora crassa


substrate_name: 4-methoxybenzyl alcohol


substrate_name: acetaldehyde


organism: Saccharomyces cerevisiae


substrate_name: Heptanal


substrate_name: hexanal


organism: Brassica napus subsp. rapifera

substrate_name: NADH


substrate_name: NADPH


substrate_name: coniferyl aldehyde


substrate_name: coniferyl alcohol


substrate_name: D-malate


substrate_name: NAD+


organism: Yokenella sp. WZY002

substrate_name: benzyl alcohol


substrate_name: crotonyl alcohol


substrate_name: NADP+


substrate_name: benzaldehyde


substrate_name: crotonaldehyde


enzyme_display_name: dimethylmalate dehydrogenase

organism: Pseudomonas fluorescens


organism: Pseudomonas sp.


enzyme_display_name: hydroxymethylglutaryl-CoA reductase

organism: Mycobacterium sp.

substrate_name: CoA


substrate_name: DL-mevalonate


organism: Thermus thermophilus


organism: synthetic construct


substrate_name: isocitrate


organism: Saccharum officinarum

substrate_name: sinapyl alcohol


organism: Cupriavidus necator


organism: Mycobacterium tuberculosis

substrate_name: p-aminobenzyl alcohol


organism: Phanerodontia chrysosporium


substrate_name: 3,4-dimethoxybenzyl alcohol


substrate_name: 4-hydroxy-3-methoxy-benzyl alcohol


substrate_name: phenylacetaldehyde


substrate_name: trans-cinnamaldehyde


substrate_name: NADPH


substrate_name: Unknown


organism: Thauera sp.


substrate_name: NAD+


substrate_name: 4-Hydroxybenzyl alcohol


organism: Taiwanofungus camphoratus

substrate_name: veratraldehyde


enzyme_display_name: Ketol-acid reductoisomerase (NADP(+))

organism: Escherichia coli (strain K12)

substrate_name: magnesium (with S2AL and NADPH as substrates)


substrate_name: pyruvate (at pH 8 and 37 degrees Celsius)


substrate_name: 3-hydroxypyruvate (at pH 8 and 37 degrees Celsius)


substrate_name: 2-ketovalerate (at pH 8 and 37 degrees Celsius)


substrate_name: 2-ketobutyrate (at pH 8 and 37 degrees Celsius)


substrate_name: 2-ketoisovalerate (at pH 8 and 37 degrees Celsius)


organism: Shewanella oneidensis


enzyme_display_name: ketol-acid reductoisomerase (NADP+)

organism: Alicyclobacillus acidocaldarius subsp. acidocaldarius


substrate_name: NADH


organism: Sulfurisphaera tokodaii


organism: Arabidopsis thaliana


enzyme_display_name: UniProt P93832


enzyme_display_name: 3-isopropylmalate dehydrogenase 1, chloroplastic


enzyme_display_name: 3-isopropylmalate dehydrogenase 3, chloroplastic


organism: Streptomyces avermitilis


substrate_name: Hydroxypyruvate


substrate_name: pyruvate


organism: Streptomyces ambofaciens


organism: Shewanella benthica


organism: Corynebacterium glutamicum


organism: Methanococcus aeolicus


enzyme_display_name: UniProt P9WKJ7


enzyme_display_name: 3-isopropylmalate dehydrogenase 2, chloroplastic

substrate_name: 3-isopropylmalate (at pH 7.5 and 25 degrees Celsius)


substrate_name: 3-isopropylmalate (at pH 7.5 and in reduced form)


substrate_name: NAD(+) (at pH 7.5 and in reduced form)


substrate_name: D-malate (at pH 7.5 and in reduced form)


organism: Sulfolobus acidocaldarius

substrate_name: homoisocitrate


substrate_name: NAD+


substrate_name: NADPH


substrate_name: Heptanal


substrate_name: hexanal


enzyme_display_name: UniProt C0IR58

organism: Ralstonia sp.


substrate_name: NADP+


organism: Methanocaldococcus jannaschii


substrate_name: D-malate


organism: Neurospora crassa


enzyme_display_name: UniProt Q2FWK4

organism: Staphylococcus aureus


enzyme_display_name: UniProt Q5SIY4

organism: Thermus thermophilus


substrate_name: 2-ketopantoate (at pH 8 and 37 degrees Celsius)


substrate_name: 2-acetolactate (at pH 8 and 37 degrees Celsius)


substrate_name: NADP


substrate_name: NADH


organism: Slackia exigua (strain ATCC 700122 / DSM 15923 / CIP 105133 / JCM 11022 / KCTC 5966 / S-7)

substrate_name: NADPH (at pH 7)


substrate_name: NADH (at pH 7)


organism: Spinacia oleracea


organism: Saccharomyces cerevisiae

substrate_name: (2R,3S)-3-propylmalic acid


organism: Pyrococcus horikoshii


substrate_name: isocitrate


organism: Lactococcus lactis subsp. lactis (strain IL1403)


enzyme_display_name: UniProt C8WR67

organism: Alicyclobacillus acidocaldarius subsp. acidocaldarius


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: NADPH (with HP as substrate)


substrate_name: HP


substrate_name: alpha-ketoadipate


enzyme_display_name: UniProt D2YZL2


enzyme_display_name: UniProt P50455

organism: Sulfurisphaera tokodaii


enzyme_display_name: 3-isopropylmalate dehydrogenase

substrate_name: malate


organism: Arabidopsis thaliana


organism: Corynebacterium glutamicum


enzyme_display_name: homoisocitrate dehydrogenase


substrate_name: NAD+


enzyme_display_name: UniProt Q5SIJ1


substrate_name: homoisocitrate


enzyme_display_name: Aldo-keto reductase family 1 member A1

organism: Rattus norvegicus

substrate_name: acrolein


enzyme_display_name: UniProt Q8E9N3

organism: Shewanella oneidensis


organism: Escherichia coli (strain K12)

substrate_name: NAD (at 40 degrees Celsius)


enzyme_display_name: Ketol-acid reductoisomerase (NADP(+))

substrate_name: NADPH


enzyme_display_name: aryl-alcohol dehydrogenase

organism: Lactiplantibacillus plantarum WCFS1

substrate_name: benzyl alcohol


enzyme_display_name: ketol-acid reductoisomerase (NADP+)


enzyme_display_name: aryl-alcohol dehydrogenase (NADP(+))

organism: Ralstonia sp.


enzyme_display_name: ketol-acid reductoisomerase (NADP(+))

organism: Escherichia coli


substrate_name: NADP+


substrate_name: alpha-Ketovaline


substrate_name: pyruvate


organism: Streptomyces avermitilis


substrate_name: Hydroxypyruvate


organism: Acidithiobacillus ferrooxidans


substrate_name: NAD


substrate_name: D-malate


substrate_name: L-malate


organism: Sulfolobus acidocaldarius

substrate_name: NADH


organism: Thermus thermophilus


organism: Meiothermus ruber


organism: Streptomyces ambofaciens


organism: Yokenella sp. WZY002

substrate_name: benzaldehyde


substrate_name: crotonaldehyde


substrate_name: crotonyl alcohol


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: beta-isopropylmalate


substrate_name: isocitrate


substrate_name: homoisocitrate


organism: Mycobacterium tuberculosis


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


organism: Saccharomyces cerevisiae


enzyme_display_name: Homoisocitrate dehydrogenase


substrate_name: NAD+


substrate_name: threo-D,L-isopropylmalate


substrate_name: NADPH


substrate_name: NADP+


organism: Streptococcus pneumoniae


enzyme_display_name: hydroxymethylglutaryl-CoA reductase

organism: Pseudomonas sp. 'mevalonii'

substrate_name: CoASH


substrate_name: (R,S)-mevalonate


substrate_name: Tartrate


substrate_name: malate


substrate_name: isopropylmalate


organism: Bacillus subtilis


organism: Arabidopsis thaliana


enzyme_display_name: glyoxylate reductase (NADP+)

organism: Oryza sativa Japonica Group


substrate_name: glyoxylate


substrate_name: NADH


substrate_name: Unknown


enzyme_display_name: hydroxypyruvate reductase

organism: Methylorubrum extorquens AM1


substrate_name: Hydroxypyruvate


substrate_name: glycerate


organism: Oryza sativa


substrate_name: Succinic semialdehyde


substrate_name: CoA


organism: Malus domestica


organism: Staphylococcus aureus


organism: Thermus thermophilus


mutation_signature: stopped flow experiment


substrate_name: glycolate


organism: Saccharolobus solfataricus


organism: Escherichia coli


enzyme_display_name: phosphoglycerate dehydrogenase

organism: Bombyx mori


enzyme_display_name: tartrate dehydrogenase

organism: Sus scrofa

substrate_name: NADH; H+; 2-Hydroxy-3-oxosuccinate


organism: Pseudomonas putida


enzyme_display_name: diiodophenylpyruvate reductase

organism: Bos taurus


substrate_name: NAD+


substrate_name: D-malate


substrate_name: H+; NADH; 2-Oxoglutarate


substrate_name: NADH; H+; 2-Oxoglutarate


substrate_name: 2-Oxoglutarate; H+; NADH


substrate_name: H+; 2-Oxoglutarate; NADH


substrate_name: oxaloacetate


enzyme_display_name: 3-hydroxybenzyl-alcohol dehydrogenase

organism: Penicillium urticae

substrate_name: 3-Hydroxybenzyl alcohol


enzyme_display_name: UniProt Q76KF5

organism: Entamoeba histolytica


substrate_name: phosphohydroxypyruvate


substrate_name: NADPH


substrate_name: NADH


organism: Sulfurisphaera tokodaii


enzyme_display_name: UniProt O43175

organism: Homo sapiens


enzyme_display_name: D-3-phosphoglycerate dehydrogenase


organism: Rickettsia prowazekii


substrate_name: glycerone phosphate


substrate_name: reduced nicotinamide hypoxanthine dinucleotide


organism: Mycobacterium tuberculosis


substrate_name: Dihydroxyfumarate


enzyme_display_name: D-3-phosphoglycerate dehydrogenase 1

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


enzyme_display_name: D-3-phosphoglycerate dehydrogenase 2


enzyme_display_name: UniProt P0A9T0


organism: Escherichia coli (strain K12)

substrate_name: NADP(+)


substrate_name: acetylpyridine


substrate_name: Thionicotinamide


organism: Streptomyces coelicolor


substrate_name: L-Tartrate


substrate_name: D-malate


substrate_name: beta-isopropylmalate


organism: Aphanothece halophytica


substrate_name: NAD+


substrate_name: Glycerate 3-phosphate


enzyme_display_name: D-3-phosphoglycerate dehydrogenase 2, chloroplastic

organism: Arabidopsis thaliana

substrate_name: 3-phosphonooxypyruvate (at pH 7.1)


substrate_name: NADH (at pH 7.1)


substrate_name: Unknown


organism: Cereibacter sphaeroides


substrate_name: oxaloacetate


organism: Escherichia coli


substrate_name: pyridinealdehyde adenine dinucleotide


organism: Glycine max

substrate_name: NADH


substrate_name: NADPH


enzyme_display_name: ketol-acid reductoisomerase (NADP+)

substrate_name: Hydroxypyruvate


organism: Campylobacter jejuni


organism: Triticum aestivum


enzyme_display_name: aryl-alcohol dehydrogenase

organism: Streptomyces sp.


substrate_name: cinnamyl alcohol


substrate_name: coniferyl aldehyde


substrate_name: alpha-ketoglutarate


enzyme_display_name: fructuronate reductase

substrate_name: D-fructuronate


substrate_name: D-mannonate


enzyme_display_name: lactaldehyde reductase

substrate_name: L-lactaldehyde


enzyme_display_name: (R)-aminopropanol dehydrogenase


enzyme_display_name: 3-isopropylmalate dehydrogenase

substrate_name: D-malate


organism: Pseudomonas fluorescens

substrate_name: NAD+


substrate_name: (R)-malate


enzyme_display_name: malate dehydrogenase (NADP+)

organism: Sorghum bicolor


organism: Thermus thermophilus

substrate_name: isopropylmalate


substrate_name: tert-butylmalate


organism: Pseudomonas aeruginosa

substrate_name: erythro-Lg-beta-isopropylmalate


organism: Salmonella enterica subsp. enterica serovar Typhimurium


enzyme_display_name: L-threonine 3-dehydrogenase

organism: Thermoplasma volcanium

substrate_name: L-threonine


substrate_name: L-serine


substrate_name: L-threoninol


enzyme_display_name: acylglycerone-phosphate reductase

organism: Cavia porcellus

substrate_name: NADPH


substrate_name: Hexadecyldihydroxyacetone phosphate


organism: uncultured archaeon


substrate_name: 1-O-Hexadecyl glycerone phosphate; NADPH; H+


substrate_name: NADH


organism: Carthamus tinctorius

substrate_name: acetoacetyl-[acyl-carrier protein]


organism: Aquarana catesbeiana


enzyme_display_name: all-trans-retinol dehydrogenase (NAD+)

organism: Branchiostoma floridae

substrate_name: all-trans-retinal


enzyme_display_name: pantoate 4-dehydrogenase

organism: Pseudomonas sp. P2

substrate_name: D-pantoate


substrate_name: ketopantoate


organism: Kangiella koreensis


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6

organism: Rattus norvegicus


substrate_name: androsterone


substrate_name: dihydrotestosterone


substrate_name: testosterone


substrate_name: estradiol


substrate_name: NAD


substrate_name: NADP


organism: Pyrococcus horikoshii

substrate_name: NAD+


substrate_name: L-threonine


organism: Homo sapiens


substrate_name: all-trans-retinol


substrate_name: allopregnanolone


substrate_name: dehydroepiandrosterone


enzyme_display_name: UniProt Q97BK3


substrate_name: L-serine


enzyme_display_name: pyridoxal 4-dehydrogenase

organism: Microbacterium luteolum

substrate_name: pyridoxal


substrate_name: L-fucose


substrate_name: L-Xylose


substrate_name: D-arabinose


substrate_name: NADP+


organism: Saccharomyces cerevisiae

substrate_name: NADPH


substrate_name: acetoacetyl-CoA


organism: Mus musculus


enzyme_display_name: UniProt P14697

organism: Cupriavidus necator


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: acetoacetyl-CoA (at 25 degrees Celsius and at pH 7.0)


substrate_name: NADPH (at 25 degrees Celsius and at pH 7.0)


organism: Arthrobacter sp.


organism: Pyrococcus furiosus


enzyme_display_name: UniProt D6PBM7


enzyme_display_name: Dehydrogenase/reductase SDR family member 6


organism: Mesorhizobium loti


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)


organism: Thermococcus kodakarensis KOD1


organism: Cytophaga sp.


enzyme_display_name: UniProt Q8KZM4


substrate_name: NAD


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH7

substrate_name: 10-OH-decanoic acid (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: hexanol (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: hexanal (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 2-hexenol (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 2-hexenal (with 0.1 M sodium phosphate at pH 7.5)


substrate_name: 4-hydroxynonenal (with 0.1 M sodium phosphate at pH 7.5)


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH1B

substrate_name: all-trans-4-hydroxyretinol (in allele ADH1B*1)


substrate_name: all-trans-4-oxoretinal (in allele ADH1B*1)


substrate_name: all-trans-retinol


substrate_name: all-trans-retinal


enzyme_display_name: Retinol dehydrogenase 16


substrate_name: NADP


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: allopregnanolone


substrate_name: dehydroepiandrosterone


substrate_name: androsterone


substrate_name: dihydrotestosterone


organism: Thermoplasma volcanium

substrate_name: L-serine


substrate_name: L-Threonine


substrate_name: estradiol


substrate_name: L-threonine


substrate_name: NAD(+)


substrate_name: D-Arabinose


substrate_name: L-Fucose


substrate_name: L-Xylose


substrate_name: Pyridoxal


substrate_name: NADPH (with homotetramer)


substrate_name: 1,4-benzoquinone (with homotetramer)


substrate_name: acetoacetyl-CoA


substrate_name: NADPH


enzyme_display_name: Fatty acid synthase

substrate_name: acetyl-CoA


substrate_name: malonyl-CoA


substrate_name: butanoyl-CoA


organism: Persea americana


substrate_name: acetoacetyl-N-acetylcysteamine


enzyme_display_name: NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: p-nitrophenylacetate


substrate_name: p-nitrophenylbutyrate


substrate_name: Retinol


substrate_name: all-trans-retinaldehyde (in allele ADH1B*2)


substrate_name: all-trans-retinol (in allele ADH1B*2)


enzyme_display_name: L-threonine 3-dehydrogenase

organism: Escherichia coli (strain K12)

substrate_name: L-threonine (at 37 degrees Celsius and pH 8.4)


substrate_name: NAD(+) (at 37 degrees Celsius and pH 8.4)


enzyme_display_name: 4-oxoproline reductase

organism: Oryctolagus cuniculus


substrate_name: NADH


organism: Pyrococcus horikoshii

substrate_name: NAD+


substrate_name: NADP+


organism: Homo sapiens

substrate_name: all-trans-Retinal


organism: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

substrate_name: NADP(+) (at 65 degrees Celsius)


organism: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

substrate_name: butan-2,3-diol (at 70 degrees Celsius)


organism: Escherichia coli


enzyme_display_name: All-trans-retinol dehydrogenase [NAD(+)] ADH4

substrate_name: all-trans-retinol


substrate_name: all-trans-retinal


organism: Kangiella koreensis


organism: Mus musculus


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase 13


enzyme_display_name: ketol-acid reductoisomerase (NADP+)

organism: Oryza sativa


substrate_name: NADPH


substrate_name: Hydroxypyruvate


organism: Mycobacterium tuberculosis


enzyme_display_name: hydroxymethylglutaryl-CoA reductase

organism: Burkholderia cenocepacia


organism: Pseudomonas sp. 'mevalonii'


enzyme_display_name: phosphoglycerate dehydrogenase


organism: Bacillus subtilis


substrate_name: Unknown


organism: Mycolicibacterium smegmatis


organism: Arabidopsis thaliana


enzyme_display_name: carnitine 3-dehydrogenase

organism: Xanthomonas translucens

substrate_name: carnitine


substrate_name: L-carnitine


enzyme_display_name: apiose 1-reductase

organism: Micrococcus sp.


substrate_name: D-apiitol


substrate_name: D-apiose


organism: Klebsiella aerogenes


enzyme_display_name: aromatic 2-oxoacid reductase

organism: Candida maltosa


substrate_name: p-hydroxyphenylpyruvate


substrate_name: Indolepyruvate


substrate_name: p-hydroxyphenyllactate


substrate_name: D-phenyllactate


substrate_name: NAD+


substrate_name: indolelactate


enzyme_display_name: ribose 1-dehydrogenase (NADP+)

organism: Sus scrofa

substrate_name: D-xylose


substrate_name: D-arabinose


organism: Rhizobium meliloti (strain 1021)


substrate_name: NAD(+)


substrate_name: L-carnitinyl-CoA


substrate_name: betainyl-CoA


enzyme_display_name: Aldo-keto reductase family 1 member C2

organism: Homo sapiens

substrate_name: (s)-tetralol (oxidation)


substrate_name: benzene dihydrodiol (oxidation)


substrate_name: prostaglandin D2 (reduction)


enzyme_display_name: Aldo-keto reductase family 1 member C1

substrate_name: (s)-tetralol


substrate_name: NADPH


substrate_name: NADP(+)


substrate_name: allopregnanolone (oxidation)


substrate_name: carnitine


enzyme_display_name: L-carnitine dehydrogenase

organism: Pseudomonas sp


organism: Streptomyces viridifaciens


substrate_name: Hydroxypyruvate


substrate_name: pyruvate


substrate_name: (s)-indan-1-ol (oxidation)


substrate_name: 5alpha-androstan-3,17-dione (reduction)


substrate_name: progesterone (reduction)


substrate_name: NADH


substrate_name: testosterone (oxidation)


organism: Alcaligenes sp.

substrate_name: NAD+


substrate_name: L-carnitine


enzyme_display_name: indanol dehydrogenase


enzyme_display_name: Aromatic 2-oxoacid reductase

organism: Clostridium sporogenes (strain ATCC 7955 / DSM 767 / NBRC 16411 / NCIMB 8053 / NCTC 8594 / PA 3679)

substrate_name: phenylpyruvate


organism: Rhizobium sp

substrate_name: NAD(+)


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: L-carnitine (at pH 9.5)


substrate_name: 3-dehydrocarnitine (at pH 7.2)


substrate_name: NADH (at pH 7.2)


organism: Clostridium sporogenes (strain ATCC 15579)

substrate_name: p-hydroxyphenylpyruvate


substrate_name: NADH (in the presence of indolepyruvate)


substrate_name: indolelactate


substrate_name: p-hydroxyphenyllactate


substrate_name: NAD(+) (in the presence of indolelactate)


enzyme_display_name: D-arabinose 1-dehydrogenase (NAD+)

organism: Pseudomonas sp.

substrate_name: NADP+


substrate_name: L-fucose


substrate_name: D-arabinose


enzyme_display_name: UniProt Q96ZY1

organism: Sulfurisphaera tokodaii


substrate_name: D-glucose


enzyme_display_name: UniProt Q977U7

organism: Haloferax mediterranei

substrate_name: NAD(P)+


substrate_name: beta-D-glucose


enzyme_display_name: glucose 1-dehydrogenase (NADP(+))


enzyme_display_name: UniProt Q5SLC4

organism: Thermus thermophilus HB8

substrate_name: (R)-indanol


substrate_name: alpha-tetralone


substrate_name: D-fucose


substrate_name: D-xylose


substrate_name: D-talose


substrate_name: D-galactosamine


substrate_name: cellobiose


substrate_name: cis-benzene dihydrodiol


substrate_name: isatin


enzyme_display_name: UniProt Q9HK51

organism: Thermoplasma acidophilum

substrate_name: D-mannose


enzyme_display_name: D-threo-aldose 1-dehydrogenase

organism: Agrobacterium tumefaciens

substrate_name: D-galactose


substrate_name: L-fucose (at 37 degrees Celsius)


substrate_name: L-galactose (at 37 degrees Celsius)


substrate_name: D-arabinose (at 37 degrees Celsius)


substrate_name: NADP(+) (at 37 degrees Celsius)


substrate_name: NAD(+) (at 37 degrees Celsius)


enzyme_display_name: aldose 1-dehydrogenase (NAD+)

substrate_name: (R)-tetralol


substrate_name: L-fucose


substrate_name: (R)-indanol


substrate_name: alpha-tetralone


substrate_name: D-fucose


enzyme_display_name: glucose 1-dehydrogenase (NADP+)

substrate_name: D-glucose


substrate_name: NADP+


substrate_name: NAD+


enzyme_display_name: galactose 1-dehydrogenase (NADP+)

organism: Pseudomonas putida


enzyme_display_name: D-arabinose 1-dehydrogenase [NAD(P)+]

organism: Candida albicans


substrate_name: D-arabinose


substrate_name: L-galactose


substrate_name: Unknown


enzyme_display_name: glucose 1-dehydrogenase (NAD+)

organism: Saccharolobus solfataricus


substrate_name: D-xylose


organism: Gluconobacter cerinus


substrate_name: NADPH


substrate_name: D-mannose


organism: Sus scrofa


substrate_name: digitoxose


substrate_name: D-ribose


enzyme_display_name: glucose 1-dehydrogenase (NAD(+))

organism: synthetic construct


enzyme_display_name: glucose 1-dehydrogenase [NAD(P)(+)]


substrate_name: D-altrose


organism: Aureobasidium pullulans


substrate_name: NAD(P)+


organism: Halococcus saccharolyticus


organism: Ovis aries aries


organism: Acinetobacter sp.


substrate_name: L-fucose


enzyme_display_name: sorbose 5-dehydrogenase (NADP+)

organism: Saccharomyces cerevisiae


substrate_name: 5-Keto-D-fructose 1-phosphate


organism: Neurospora crassa


organism: Trinickia caryophylli


substrate_name: L-Glucose


organism: Pseudomonas sp.


organism: Filobasidium uniguttulatum


organism: Rattus norvegicus


organism: Clostridium pasteurianum


substrate_name: D-galactose


enzyme_display_name: aldose 1-dehydrogenase

organism: Pseudomonas reinekei

substrate_name: D-Glucose; NAD+


organism: Corynebacterium sp.


substrate_name: NADP+


organism: Oryctolagus cuniculus

substrate_name: NAD+


enzyme_display_name: L-fucose dehydrogenase

organism: Homo sapiens

substrate_name: NAD(+)


enzyme_display_name: Glucose 1-dehydrogenase

organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)

substrate_name: glucose


substrate_name: NADP(+)


enzyme_display_name: D-arabinose 1-dehydrogenase (NAD+)

substrate_name: D-arabinose


organism: Gluconobacter oxydans


substrate_name: D-glucose


substrate_name: oestradiol


organism: Rhizobium leguminosarum bv. trifolii


organism: Bemisia argentifolii

substrate_name: fructose


organism: Agrobacterium tumefaciens


organism: Saccharolobus solfataricus

substrate_name: NAD(+) (at 70 degrees Celsius and pH 8)


substrate_name: NADP(+) (at 70 degrees Celsius and pH 8)


enzyme_display_name: aldose 1-dehydrogenase (NAD(+))

organism: Thermus thermophilus

substrate_name: L-Arabinose


substrate_name: D-Talose


substrate_name: cellobiose


substrate_name: cis-benzene dihydrodiol


substrate_name: D-galactose


organism: Dickeya chrysanthemi

substrate_name: NADH


substrate_name: lactose


substrate_name: (R)-indanol


substrate_name: (R)-tetralol


substrate_name: (S)-indanol


substrate_name: (S)-tetralol


substrate_name: L-Fucose


substrate_name: D-Glucosamine


substrate_name: D-Galactosamine


substrate_name: D-Xylose


substrate_name: D-Fucose


enzyme_display_name: fructose 5-dehydrogenase (NADP+)

substrate_name: NADPH


organism: Gluconobacter cerinus


substrate_name: NADP+


substrate_name: 5-Keto-D-fructose 1-phosphate


substrate_name: D-fructose


organism: Pseudomonas sp.


enzyme_display_name: 3-dehydro-L-gulonate 2-dehydrogenase

organism: Klebsiella aerogenes


organism: Escherichia coli (strain K12)


enzyme_display_name: (R)-aminopropanol dehydrogenase

organism: Escherichia coli


enzyme_display_name: fructuronate reductase

substrate_name: D-tagaturonate


enzyme_display_name: mannitol 2-dehydrogenase (NADP+)

organism: Agaricus bisporus


enzyme_display_name: L-arabinose 1-dehydrogenase (NAD(P)(+))

organism: Azospirillum brasilense

substrate_name: NADP(+) (at 30 degrees Celsius and pH 9.0)


substrate_name: NAD(+) (at 30 degrees Celsius and pH 9.0)


enzyme_display_name: ketol-acid reductoisomerase (NADP+)


organism: Agaricus campestris


substrate_name: D-mannitol


organism: Starmerella magnoliae


substrate_name: NADH


substrate_name: ribose


substrate_name: D-mannose


substrate_name: Unknown


organism: Uromyces viciae-fabae


organism: Limosilactobacillus reuteri


substrate_name: NAD+


organism: Fusarium graminearum


organism: Aspergillus parasiticus


substrate_name: D-arabinitol


organism: Erwinia sp.


substrate_name: D-arabinose


enzyme_display_name: UDP-N-acetylglucosamine 6-dehydrogenase

substrate_name: UDP-N-acetyl-D-glucosamine


organism: Pseudomonas aeruginosa

substrate_name: UDP-N-acetyl-D-glucosamine; NAD+; H2O


organism: Micrococcus luteus


organism: Salmonella enterica subsp. enterica serovar Typhi


enzyme_display_name: ribitol-5-phosphate 2-dehydrogenase

organism: Lacticaseibacillus casei


substrate_name: D-ribitol 5-phosphate


enzyme_display_name: GDP-mannose 6-dehydrogenase

organism: Saccharina japonica


substrate_name: GDP-D-mannose


organism: Alcaligenes sp.


organism: Penicillium chrysogenum

substrate_name: NADP+


organism: Gluconobacter oxydans

substrate_name: NADPH


substrate_name: D-fructose


organism: Lactobacillus casei

substrate_name: D-Ribulose 5-phosphate; NADH; H+


organism: Diplodia viticola Desm.


organism: Lactobacillus intermedius


organism: Tuber borchii


organism: Escherichia coli (strain K12)


substrate_name: D-gluconate


substrate_name: NAD(+)


substrate_name: UDP-GlcNAc


substrate_name: NADP(+)


enzyme_display_name: Probable NADP-dependent mannitol dehydrogenase

organism: Yarrowia lipolytica (strain CLIB 122 / E 150)


substrate_name: ribulose


organism: Agaricus bisporus

substrate_name: D-mannitol


substrate_name: NADP(+) (refolded enzyme)


organism: Cladosporium herbarum


organism: Salmonella typhi


enzyme_display_name: dTDP-4-dehydrorhamnose reductase

organism: Acanthamoeba polyphaga Mimivirus


organism: Lactiplantibacillus plantarum


substrate_name: D-ribulose 5-phosphate


organism: Salmonella typhimurium


substrate_name: NADH


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


organism: Arabidopsis thaliana


organism: Aneurinibacillus thermoaerophilus


enzyme_display_name: NADP-dependent mannitol dehydrogenase

organism: Alternaria alternata


organism: Davidiella tassiana

substrate_name: NADP(+) (at pH 7.5)


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: dTDP-6-deoxy-L-mannose (at pH 6.5)


enzyme_display_name: hydroxymethylglutaryl-CoA reductase

organism: Pseudomonas sp. 'mevalonii'

substrate_name: mevalonate


organism: Oryza sativa Japonica Group

substrate_name: Unknown


organism: Oryza sativa


enzyme_display_name: phosphoglycerate dehydrogenase

organism: Escherichia coli


substrate_name: DL-mevalonate


enzyme_display_name: aryl-alcohol dehydrogenase

organism: Streptomyces sp.

substrate_name: coniferyl alcohol


organism: Mycobacterium tuberculosis


organism: Homo sapiens


enzyme_display_name: glyoxylate reductase (NADP+)

organism: Zea mays

substrate_name: NADH; Glyoxylate; H+


enzyme_display_name: malate dehydrogenase (NADP+)

organism: Sorghum bicolor

substrate_name: Oxaloacetate; H+; NADPH


enzyme_display_name: L-threonine 3-dehydrogenase

organism: Capra hircus

substrate_name: NAD+; L-Threonine


organism: Dictyostelium discoideum

substrate_name: Sepiapterin; NADPH; H+


organism: Streptomyces exfoliatus


enzyme_display_name: Aldo-keto reductase family 1 member C4


enzyme_display_name: Dehydrogenase/reductase SDR family member 9

substrate_name: NADH tested with dihydrotestosterone


enzyme_display_name: Aldo-keto reductase family 1 member C3


enzyme_display_name: Aldo-keto reductase family 1 member C1


enzyme_display_name: Retinol dehydrogenase 16

substrate_name: CRBP-all-trans-retinol


enzyme_display_name: 3-hydroxyacyl-CoA dehydrogenase type-2

substrate_name: 5-alpha-pregnan-20-beta-ol-3-one (in the presence of 1 mM NAD, at pH 9.3 and 25 degrees Celsius)


enzyme_display_name: 17-beta-hydroxysteroid dehydrogenase type 6


organism: Drosophila melanogaster

substrate_name: NAD (in the presence of (3S)-3-hydroxybutanoyl-CoA, at pH 9.3 and 25 degrees Celsius)


organism: Rattus norvegicus


enzyme_display_name: Retinol dehydrogenase 5

organism: Bos taurus


organism: Mus musculus


organism: Macaca fuscata fuscata


enzyme_display_name: Aldo-keto reductase family 1 member B1


enzyme_display_name: Aldo-keto reductase family 1 member B10

substrate_name: GS-acrolein


enzyme_display_name: Aldo-keto reductase family 1 member B15

substrate_name: 3-alpha,17-beta-androstandiol (tested with isoform 1 in the oxidative reaction)


enzyme_display_name: Aldo-keto reductase family 1 member A1


enzyme_display_name: Carbonyl reductase [NADPH] 1

organism: Sus scrofa

substrate_name: 9,1 O-phenanthrene-quinone


enzyme_display_name: glycerol dehydrogenase (NADP+)

organism: Trichoderma reesei

substrate_name: H+; NADPH; Dihydroxyacetone


enzyme_display_name: Glycerol dehydrogenase

organism: Escherichia coli (strain K12)


enzyme_display_name: (S,S)-butanediol dehydrogenase

organism: Corynebacterium glutamicum

substrate_name: L-acetoin


enzyme_display_name: glyoxylate reductase (NADP+)

substrate_name: H+; NADPH; 3-Hydroxypyruvate


substrate_name: Glyoxylate; H+; NADH


organism: Saccharomyces cerevisiae

substrate_name: NADPH; H+; Glyoxylate


organism: Escherichia coli

substrate_name: NADPH; Glyoxylate; H+


substrate_name: H+; NADPH; Glyoxylate


organism: Spinacia oleracea

substrate_name: Glyoxylate; H+; NADPH


organism: Arabidopsis thaliana


organism: Thermus thermophilus

substrate_name: NADH


substrate_name: NADPH