organism: Bacillus licheniformis

substrate_name: L-Arabinose


enzyme_display_name: L-arabinose isomerase

source_db: oed

ki_display: Not reported

protein_accession_database: UniProt

kcat_over_km_origin: calculated

source_license: CC BY 4.0

km_unit: mM


enzyme_display_name: mannose isomerase

organism: Escherichia coli

substrate_name: D-fructose

source_db: brenda

verification_status: corrected

mutation_signature: Unknown


protein_accession_database: NCBI Protein


substrate_name: D-Mannose


enzyme_display_name: mannose-6-phosphate isomerase

organism: Bacillus subtilis

substrate_name: D-Lyxose

verification_status: verified


substrate_name: D-ribose


substrate_name: L-allose


organism: Geobacillus thermodenitrificans

substrate_name: D-galactose

verification_status: unverified


enzyme_display_name: glucose-6-phosphate isomerase

organism: Aeropyrum pernix

substrate_name: D-fructose 6-phosphate

kcat_display: Not reported

kcat_over_km_display: Not reported


substrate_name: D-mannose 6-phosphate


substrate_name: D-glucose 6-phosphate


enzyme_display_name: ribose-5-phosphate isomerase

substrate_name: D-Allose 6-phosphate


substrate_name: D-Ribose 5-phosphate


organism: Thermoplasma acidophilum


organism: Bacillus halodurans


organism: Anoxybacillus flavithermus


enzyme_display_name: xylose isomerase

organism: Streptomyces rubiginosus

substrate_name: D-glyceraldehyde


substrate_name: D-Xylose


organism: Saccharomyces cerevisiae


organism: Vibrio sp.

substrate_name: D-glucose


organism: Pyrobaculum aerophilum


organism: Geobacillus stearothermophilus

substrate_name: L-arabinose

source_db: uniprot


organism: Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)

substrate_name: fructose 6-phosphate (at 50 degrees Celsius)


substrate_name: mannose 6-phosphate (at 80 degrees Celsius)


organism: Methanocaldococcus jannaschii


organism: Arabidopsis thaliana


substrate_name: glucose 6-phosphate (at 50 degrees Celsius)


organism: Mycobacterium tuberculosis


organism: Thermoanaerobacter mathranii

substrate_name: D-fucose


organism: Lactobacillus plantarum

substrate_name: D-Galactose


substrate_name: L-Arabinose


organism: Lactobacillus sakei


organism: Rattus norvegicus


organism: Thermoanaerobacter ethanolicus

substrate_name: D-xylose


organism: Escherichia coli (strain K12)

substrate_name: D-allose 6-phosphate


organism: Pyrococcus furiosus

substrate_name: L-talose

source_license: CC BY 4.0; CC BY-NC-ND 4.0


organism: [Clostridium] hylemonae

substrate_name: D-galactose


substrate_name: D-ribose 5-phosphate (at 37 degrees Celsius)


organism: Homo sapiens

substrate_name: D-mannose 6-phosphate


organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: fructose 6-phosphate


organism: Pseudoalteromonas haloplanktis


organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)


organism: Pseudomonas aeruginosa

substrate_name: D-Mannose 6-phosphate


organism: Saccharomyces cerevisiae


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


substrate_name: D-Fructose 6-phosphate


organism: Chlorella variabilis


organism: Oryctolagus cuniculus


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Mycobacterium tuberculosis

substrate_name: D-fructose 6-phosphate


organism: Geobacillus thermodenitrificans

substrate_name: L-arabinose


substrate_name: D-Glucose 6-phosphate


organism: Archaeoglobus fulgidus


organism: Alicyclobacillus hesperidum


organism: Thermus thermophilus

substrate_name: D-glucose


substrate_name: D-glucose; D-mannose


substrate_name: Unknown

km_display: Not reported

ki_unit: mM


organism: Limosilactobacillus fermentum


substrate_name: D-glucose 6-phosphate


organism: Actinoplanes missouriensis


substrate_name: D-fructose


organism: Streptomyces pseudogriseolus


organism: Thermococcus litoralis


substrate_name: D-xylose


organism: Bacillus licheniformis


organism: Geobacillus stearothermophilus


substrate_name: L-fucose


organism: Brucella anthropi

substrate_name: D-allose


substrate_name: L-ribulose


organism: Bacillus subtilis

substrate_name: D-ribose


substrate_name: L-allose


substrate_name: D-mannose


substrate_name: L-ribose


organism: Clostridioides difficile

substrate_name: L-talose


substrate_name: D-ribose 5-phosphate


organism: Streptomyces olivochromogenes

substrate_name: xylulose


substrate_name: D-fructose 6-phosphate


substrate_name: L-arabinose


substrate_name: D-galactose


organism: Escherichia coli


organism: Arthrobacter sp.

substrate_name: D-Lyxose


substrate_name: D-glucose


organism: Homo sapiens

substrate_name: fructose 6-phosphate


substrate_name: glucose 6-phosphate


organism: Geobacillus thermodenitrificans


substrate_name: Unknown


organism: Methanosarcina mazei


substrate_name: D-glucose 6-phosphate


organism: Oryctolagus cuniculus


organism: Sinorhizobium meliloti


organism: Spinacia oleracea


organism: Streptomyces sp.


substrate_name: D-xylose


organism: Streptomyces albus


substrate_name: L-rhamnose


organism: Thermoanaerobacterium saccharolyticum


substrate_name: D-fructose


organism: Lactococcus lactis


organism: Thermus thermophilus

substrate_name: D-mannose


organism: Alicyclobacillus acidocaldarius


organism: Alicyclobacillus hesperidum


organism: Salmonella enterica


organism: Anoxybacillus flavithermus


organism: Bacillus subtilis

substrate_name: L-aldose


substrate_name: L-ribulose


organism: Bacillus sp. (in: firmicutes)


organism: Bifidobacterium adolescentis


organism: Bifidobacterium longum


organism: Candida albicans

substrate_name: mannose 6-phosphate


organism: Brucella anthropi

substrate_name: D-allose


organism: Bacteroides stercoris


substrate_name: D-mannose 6-phosphate


organism: Cricetulus griseus


organism: Enterococcus faecium

substrate_name: L-arabinose


organism: Escherichia coli

substrate_name: D-ribose 5-phosphate


substrate_name: beta-D-mannose 6-phosphate


substrate_name: D-tagatose


substrate_name: D-galactose


organism: Geobacillus stearothermophilus


organism: Geobacillus kaustophilus


substrate_name: D-xylulose


organism: Halalkalibacterium halodurans


organism: Heyndrickxia coagulans


substrate_name: D-glucose


organism: Homo sapiens

substrate_name: D-fructose 6-phosphate


substrate_name: D-glucose 6-phosphate


organism: Klebsiella aerogenes


substrate_name: glucose 6-phosphate


substrate_name: Unknown


organism: Lactiplantibacillus plantarum


organism: Lentilactobacillus parabuchneri


organism: Latilactobacillus sakei


organism: Limosilactobacillus fermentum


organism: Levilactobacillus brevis

substrate_name: D-ribose


organism: Mus musculus

substrate_name: fructose 6-phosphate


organism: Limosilactobacillus reuteri


substrate_name: D-xylose


organism: Piromyces sp.


enzyme_display_name: glutamate racemase

organism: Pediococcus pentosaceus

substrate_name: L-Glu


organism: Lathyrus oleraceus

substrate_name: D-ribulose 5-phosphate


organism: Saccharomyces cerevisiae

substrate_name: D-mannose 6-phosphate


organism: Pseudomonas aeruginosa


organism: Streptomyces pseudogriseolus

substrate_name: D-glyceraldehyde


organism: Streptomyces sp. 32


organism: Streptomyces sp. 1


organism: Shewanella sp. ANA-3

substrate_name: L-arabinose


organism: Thermotoga petrophila


substrate_name: alpha-D-xylopyranose


enzyme_display_name: protein disulfide-isomerase

organism: Triticum aestivum

substrate_name: ribonuclease


organism: Thermus thermophilus

substrate_name: D-ribose 5-phosphate


organism: Arabidopsis thaliana


organism: Thermotoga neapolitana


substrate_name: D-galactose


organism: Bacillus amyloliquefaciens


organism: Bacillus cereus

substrate_name: UDP-N-acetyl-alpha-D-mannosamine


organism: Vibrio sp.

substrate_name: D-glucose


enzyme_display_name: phosphopentomutase


organism: Bacillus licheniformis


enzyme_display_name: L-rhamnose isomerase

organism: Thermobacillus composti

substrate_name: L-rhamnose


substrate_name: L-Mannose


substrate_name: D-psicose


substrate_name: D-allose


enzyme_display_name: UniProt Q75WH8

organism: Pseudomonas stutzeri

substrate_name: D-ribose

source_db: skid

source_license: CC BY-NC-ND 4.0


substrate_name: L-Lyxose


organism: Bacillus subtilis


substrate_name: L-Rhamnose


enzyme_display_name: D-lyxose ketol-isomerase

organism: Paenibacillus baekrokdamisoli

substrate_name: D-allulose


organism: Thermosediminibacter oceani

substrate_name: D-fructose


substrate_name: D-Lyxose


substrate_name: D-Mannose


enzyme_display_name: lysine 2,3-aminomutase

substrate_name: L-lysine


enzyme_display_name: beta-phosphoglucomutase

substrate_name: beta-D-glucose 1-phosphate


organism: Arthrobacter sp.


enzyme_display_name: ribulose-phosphate 3-epimerase

organism: Bacillus methanolicus

substrate_name: D-ribulose 5-phosphate


enzyme_display_name: S-ribosylhomocysteine lyase

substrate_name: S-ribosylhomocysteine


organism: Stutzerimonas stutzeri


enzyme_display_name: glucuronate isomerase

organism: Escherichia coli

substrate_name: D-Glucuronate


substrate_name: L-Xylose


substrate_name: D-glucose


substrate_name: D-altrose


substrate_name: D-xylose


substrate_name: L-rhamnulose


organism: Thermotoga maritima

substrate_name: L-rhamnose


substrate_name: L-Fructose


substrate_name: L-xylulose


substrate_name: L-Mannose


substrate_name: L-Lyxose


organism: Thermoprotei archaeon

substrate_name: D-fructose


substrate_name: D-mannose


substrate_name: D-Lyxose


substrate_name: L-ribose


enzyme_display_name: arabinose-5-phosphate isomerase

organism: Acidipropionibacterium acidipropionici

substrate_name: D-arabinose 5-phosphate


substrate_name: D-allose


organism: Clostridium tetani

substrate_name: D-ribulose 5-phosphate


organism: Caldanaerobius polysaccharolyticus


organism: Thermoflavimicrobium dichotomicum


organism: Thermofilum sp. ex4484_79


organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

substrate_name: ProFAR


organism: Bacteroides fragilis

substrate_name: Unknown


organism: Escherichia coli (strain K12)


organism: Cohnella laeviribosi


organism: Escherichia coli O157:H7


organism: Serratia proteamaculans


organism: Mesorhizobium loti

substrate_name: D-ribose


substrate_name: L-talose; L-mannose


substrate_name: L-lyxose


substrate_name: D-Mannose


substrate_name: D-xylulose


substrate_name: D-lyxose


substrate_name: D-Xylulose


organism: Thermofilum sp. (strain ex4484_79)


organism: Thermosediminibacter oceani


organism: Dictyoglomus turgidum


substrate_name: L-Fructose


substrate_name: L-xylulose


substrate_name: L-Mannose


substrate_name: L-rhamnose


substrate_name: L-Lyxose


organism: Pseudomonas stutzeri


substrate_name: L-Xylulose


substrate_name: L-Rhamnose


organism: Thermotoga maritima


organism: Caldicellulosiruptor obsidiansis


substrate_name: D-allose


organism: Caldicellulosiruptor saccharolyticus


substrate_name: D-mannose


substrate_name: L-gulose


organism: Thermoanaerobacterium saccharolyticum


substrate_name: D-ribose


substrate_name: L-ribose


substrate_name: D-Lyxose


substrate_name: D-Mannose


substrate_name: L-Ribose


substrate_name: D-fructose


organism: Thermoclostridium stercorarium


substrate_name: D-allulose


organism: Medicago truncatula

substrate_name: PrFAR


substrate_name: D-ribulose 5-phosphate


substrate_name: D-arabinose 5-phosphate


substrate_name: D-Arabinose 5-phosphate


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: D-galacturonate


substrate_name: L-Ribulose


substrate_name: D-Xylulose


organism: Bacillus licheniformis


organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

substrate_name: Ru5P (at pH 7.8 and at 37 degrees Celsius)


substrate_name: A5P (at pH 7.8 and at 37 degrees Celsius)


organism: Escherichia coli (strain K12)

substrate_name: Ru5P (at pH 8.25 and at 37 degrees Celsius)


substrate_name: A5P (at pH 8.25 and at 37 degrees Celsius)


organism: Clostridium tetani


substrate_name: Ru5P (at pH 8.5 and at 37 degrees Celsius)


substrate_name: A5P (at pH 8.5 and at 37 degrees Celsius)


substrate_name: L-rhamnose


substrate_name: L-rhamnulose


organism: Arabidopsis thaliana


organism: Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)


organism: Francisella tularensis


organism: Cohnella laeviribosi

substrate_name: D-Lyxose


substrate_name: L-lyxose


organism: Escherichia coli


organism: Serratia proteamaculans

substrate_name: D-fructose


substrate_name: D-Mannose


organism: Streptomyces coelicolor


substrate_name: D-glucuronate


organism: Thermofilum sp. (strain ex4484_79)


substrate_name: D-ribose


substrate_name: L-Mannose


substrate_name: D-allose


substrate_name: L-Lyxose


organism: Aeribacillus pallidus


substrate_name: D-mannose


substrate_name: D-xylulose


organism: Providencia stuartii


enzyme_display_name: L-arabinose isomerase

organism: Bacillus subtilis

substrate_name: L-arabinose


organism: Halalkalibacterium halodurans


organism: Dictyoglomus turgidum

substrate_name: L-ribulose


organism: Lactiplantibacillus plantarum

substrate_name: D-galactose


organism: Bacillus velezensis

substrate_name: L-ribose


substrate_name: D-arabinose 5-phosphate


substrate_name: Unknown


substrate_name: D-galacturonate


enzyme_display_name: UniProt O31662


substrate_name: L-rhamnose


enzyme_display_name: protoporphyrin ferrochelatase

substrate_name: deuteroporphyrin IX


enzyme_display_name: D-tagatose 3-epimerase

organism: Pseudomonas sp.

substrate_name: D-tagatose


enzyme_display_name: ribose isomerase

organism: Mycolicibacterium smegmatis


organism: Klebsiella aerogenes

substrate_name: D-Lyxose


substrate_name: mannose


enzyme_display_name: cysteine-S-conjugate beta-lyase

substrate_name: cystathionine


enzyme_display_name: phosphoribosylanthranilate isomerase

organism: Ogataea henricii


enzyme_display_name: corticosteroid side-chain-isomerase

organism: Mesocricetus auratus


enzyme_display_name: L-fucose isomerase

organism: Caldanaerobius polysaccharolyticus

substrate_name: L-fucose


enzyme_display_name: hydroxypyruvate isomerase

organism: Metabacillus fastidiosus

substrate_name: Hydroxypyruvate


organism: Thermotoga maritima


organism: Escherichia coli O45:K1 (strain S88 / ExPEC)


substrate_name: 5-deoxyribose 1-phosphate


organism: Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73)

substrate_name: 5-deoxy-alpha-D-ribose 1-phosphate


organism: Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)


organism: Methanocaldococcus jannaschii


organism: Caldicellulosiruptor saccharolyticus


organism: Bacillus subtilis (strain 168)

substrate_name: methylthioribose-1-phosphate (at pH 8.5 and 35 degrees Celsius)


organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

substrate_name: ProFAR


organism: Thermanaeromonas toyohensis


organism: Escherichia coli (strain K12)

substrate_name: hydroxypyruvate (at 37 degrees Celsius and pH 7.0)


substrate_name: 5-deoxy-D-ribose 1-phosphate


organism: Dictyoglomus turgidum

substrate_name: L-Fucose


organism: Klebsiella pneumoniae


substrate_name: D-arabinose


organism: Streptomyces coelicolor


enzyme_display_name: glutamate racemase

organism: Bacillus subtilis

substrate_name: D-glutamate


organism: Escherichia coli


organism: Raoultella sp.

substrate_name: L-Fuculose


substrate_name: D-ribulose


enzyme_display_name: UniProt P63224

substrate_name: D-sedoheptulose 7-phosphate


enzyme_display_name: UniProt Q93UJ2

organism: Burkholderia pseudomallei


enzyme_display_name: coproporphyrin ferrochelatase

substrate_name: coproporphyrin III


substrate_name: L-xylulose


organism: uncultured bacterium

substrate_name: D-arabino-hex-3-ulose 6-phosphate


substrate_name: D-fructose 6-phosphate


enzyme_display_name: chorismate mutase

substrate_name: chorismate


enzyme_display_name: sulfoquinovose isomerase

substrate_name: D-mannose


substrate_name: D-fructose


substrate_name: D-lyxose


substrate_name: D-xylulose


enzyme_display_name: D-sedoheptulose-7-phosphate isomerase


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


organism: Geobacillus thermopakistaniensis


organism: Thermotoga maritima


enzyme_display_name: amino-acid racemase

substrate_name: L-lysine


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


enzyme_display_name: galactose-6-phosphate isomerase

organism: Staphylococcus aureus

substrate_name: D-tagatose 6-phosphate


enzyme_display_name: UniProt Q6T1W8

organism: Aneurinibacillus thermoaerophilus


organism: Methylococcus capsulatus

substrate_name: D-arabino-3-hexulose 6-phosphate


enzyme_display_name: ribose-1,5-bisphosphate isomerase

organism: Thermococcus kodakarensis

substrate_name: alpha-D-ribose 1,5-bisphosphate


enzyme_display_name: peptidylprolyl isomerase

substrate_name: RNase T1


organism: Mycobacterium tuberculosis


substrate_name: D-Homocysteinesulfinate


enzyme_display_name: phenylpyruvate tautomerase

organism: Mycolicibacterium smegmatis


substrate_name: phenylenolpyruvate


organism: Streptomyces fradiae


organism: Pseudomonas pavonaceae

substrate_name: enol-phenylpyruvate


organism: Mus musculus


enzyme_display_name: oxaloacetate tautomerase

organism: Arabidopsis thaliana

substrate_name: enol-oxaloacetate


organism: Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

substrate_name: D-sedoheptulose 7-phosphate (at 30 degrees Celsius)


organism: Homo sapiens


organism: Escherichia coli (strain K12)

substrate_name: fumarate


substrate_name: sulfoquinovose


organism: Bos taurus


organism: Bacillus subtilis


substrate_name: keto-(p-hydroxyphenyl)pyruvate


substrate_name: enol-(p-hydroxyphenyl)pyruvate


organism: Trichinella spiralis

substrate_name: Unknown


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


organism: Bacillus subtilis (strain 168)


organism: Aneurinibacillus thermoaerophilus


substrate_name: oxaloacetate


substrate_name: acetylpyruvate


substrate_name: oxaloacetate (with oxaloacetate decarboxylase activity)


substrate_name: phenylpyruvate


substrate_name: p-hydroxyphenylpyruvate


substrate_name: D-tartrate


substrate_name: keto-oxaloacetate


substrate_name: keto-phenylpyruvate


substrate_name: (S)-malate


organism: Sus scrofa


enzyme_display_name: L-arabinose isomerase

organism: Bacillus velezensis

substrate_name: L-arabinose


enzyme_display_name: cellobiose epimerase

organism: Bacteroides fragilis

substrate_name: cellobiose


enzyme_display_name: UDP-glucose 4-epimerase

organism: Bifidobacterium bifidum

substrate_name: UDPgalactose


enzyme_display_name: adenylate cyclase

organism: Bombyx mori


organism: Bordetella pertussis


substrate_name: ATP


enzyme_display_name: aspartate racemase

substrate_name: D-Asp


substrate_name: enol-oxaloacetate


enzyme_display_name: lactoylglutathione lyase


enzyme_display_name: guanylate cyclase

substrate_name: UTP


substrate_name: GTP


enzyme_display_name: 2-hydroxymuconate tautomerase

organism: Leptothrix cholodnii

substrate_name: (2E)-2-Hydroxypenta-2,4-dienoic acid


organism: Pseudomonas putida


substrate_name: Unknown


enzyme_display_name: ribose-5-phosphate isomerase

substrate_name: D-ribose 5-phosphate


enzyme_display_name: lanosterol synthase


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


enzyme_display_name: thromboxane-A synthase

substrate_name: prostaglandin H2


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

organism: Choristoneura fumiferana

substrate_name: isopentenyl diphosphate


organism: Burkholderia lata


organism: Archaeoglobus fulgidus


substrate_name: phenylenolpyruvate


organism: Helicobacter pylori


organism: Gammaproteobacteria bacterium


substrate_name: propiolate


organism: Methylibium petroleiphilum


organism: Chloroflexus aurantiacus


organism: Cinchona robusta


substrate_name: dimethylallyl diphosphate


organism: Narcissus pseudonarcissus


enzyme_display_name: vinylacetyl-CoA Delta-isomerase

organism: Bos taurus

substrate_name: vinylacetyl-CoA


enzyme_display_name: steroid Delta-isomerase

organism: Nocardia erythropolis


organism: Saccharolobus shibatae


substrate_name: NADH


organism: Aedes aegypti


organism: Methanocaldococcus jannaschii


organism: Homo sapiens

substrate_name: dehydroepiandrosterone


organism: Rattus norvegicus

substrate_name: dihydrotestosterone (in the presence of NADPH)


organism: Streptomyces sp. (strain SA-COO)

substrate_name: cholesterol


organism: Pseudomonas putida


organism: Bacillus subtilis (strain 168)

substrate_name: (p-hydroxyphenyl)-enolpyruvate


organism: Comamonas testosteroni


organism: Escherichia coli (strain K12)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: 2-hydroxymuconate (with 2-oxo-4-hexenedioate as product)


substrate_name: isopentenyl


organism: Saccharomyces cerevisiae


organism: Chloroflexus aurantiacus


organism: Archaeoglobus fulgidus


organism: Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

substrate_name: IPP (at pH 7.6 and 37 degrees Celsius)


organism: Escherichia coli


organism: Microcystis aeruginosa

substrate_name: 2,3-diketo-5-methylthiopentyl-1-phosphate (at pH 8 and 37 degrees Celsius)


organism: Methylibium petroleiphilum


organism: Streptomyces sp.

substrate_name: Isopentenyl diphosphate


organism: Staphylococcus aureus


organism: Clostridium aminobutyricum


organism: Thermococcus kodakarensis


organism: Homo sapiens

substrate_name: dehydroepiandrosterone (in the presence of NAD(+))


substrate_name: pregnenolone (in the presence of NAD(+))


substrate_name: dihydrotestosterone (in the presence of NADH)


organism: Bacillus subtilis


substrate_name: Enol-Phenylpyruvate


organism: Pseudomonas putida


substrate_name: isopentenyl diphosphate


substrate_name: pregnenolone


substrate_name: NADPH


organism: Streptococcus pneumoniae


substrate_name: Unknown


organism: Comamonas testosteroni


enzyme_display_name: muconolactone Delta-isomerase

organism: Cupriavidus necator


enzyme_display_name: pancreatic ribonuclease

organism: Bos taurus

substrate_name: RNA


organism: Bombyx mori


substrate_name: 2',3'-cyclic UMP


substrate_name: uronic acid residues


enzyme_display_name: ribulose-phosphate 3-epimerase

substrate_name: D-ribulose 5-phosphate


substrate_name: UDPgalactose


enzyme_display_name: mandelate racemase

substrate_name: 2-hydroxy-3-butenoic acid


substrate_name: muconolactone


enzyme_display_name: protein disulfide-isomerase

substrate_name: scrambled ribonuclease


enzyme_display_name: methionine gamma-lyase

organism: Brevibacterium linens

substrate_name: L-methionine


enzyme_display_name: 4-hydroxyproline epimerase

organism: Brucella abortus


organism: Brucella suis


organism: Brucella anthropi

substrate_name: L-rhamnose


organism: Brucella melitensis


organism: Brugia malayi


substrate_name: D-allose


enzyme_display_name: mannose-6-phosphate isomerase

organism: Burkholderia cepacia

substrate_name: D-mannose 6-phosphate


enzyme_display_name: phosphoenolpyruvate mutase

organism: Burkholderia gladioli

substrate_name: Phosphonopyruvate


enzyme_display_name: glutamate racemase

organism: Burkholderia cenocepacia

substrate_name: D-glutamate


enzyme_display_name: UniProt Q2PS28

organism: Paraburkholderia acidicola

substrate_name: D-glucose


substrate_name: isomaltulose


substrate_name: Trehalulose


enzyme_display_name: UniProt D9MPF2

organism: Erwinia rhapontici

substrate_name: sucrose


enzyme_display_name: UniProt Q8KR84

organism: Klebsiella sp. LX3


organism: Saccharolobus solfataricus

substrate_name: maltoheptaose


substrate_name: maltohexaose


substrate_name: maltopentaose


substrate_name: maltotetraose


substrate_name: maltotriose


enzyme_display_name: maltose alpha-D-glucosyltransferase

organism: Deinococcus geothermalis

substrate_name: maltose


enzyme_display_name: alanine racemase

organism: Caldanaerobacter subterraneus subsp. tengcongensis

substrate_name: D-alanine


enzyme_display_name: UDP-glucose 4-epimerase

organism: Campylobacter jejuni subsp. jejuni

substrate_name: UDP-alpha-D-glucose


organism: Burkholderia pseudomallei


organism: Brevibacillus brevis

substrate_name: ATP


enzyme_display_name: isomaltulose synthase


organism: Erwinia sp. Ejp617


organism: Enterobacter hormaechei


substrate_name: alpha,alpha-trehalose


organism: Rhodococcus rhodochrous


enzyme_display_name: serine racemase

organism: Caenorhabditis elegans

substrate_name: L-serine


organism: Erwinia sp. D12


organism: Picrophilus oshimae


substrate_name: trehalose


enzyme_display_name: isobutyryl-CoA mutase

organism: Xanthobacter autotrophicus


source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)


organism: Pantoea dispersa


organism: Paraburkholderia acidicola

substrate_name: Unknown


organism: Raoultella terrigena


organism: Nostoc flagelliforme


organism: Saccharolobus solfataricus


organism: Serratia plymuthica


organism: Geobacillus kaustophilus (strain HTA426)

substrate_name: isobutyryl-CoA (in the absence of nucleotides, at pH 7.5 and 37 degrees Celsius)


substrate_name: GTP (at 37 degrees Celsius)


organism: Klebsiella pneumoniae


organism: Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)


organism: Arthrobacter ramosus


organism: Thermus aquaticus


organism: Sulfolobus acidocaldarius


organism: Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)


substrate_name: maltodextrin


substrate_name: short chain amylose


organism: Mycolicibacterium smegmatis

substrate_name: 2,4-dinitrophenyl alpha-D-glucoside (at pH 6.8 and 37 degrees Celsius)


organism: Escherichia coli

substrate_name: CO2; Aminoimidazole ribotide


enzyme_display_name: squalene--hopene cyclase

organism: Alicyclobacillus acidocaldarius

substrate_name: H2O; Squalene

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


substrate_name: Squalene


source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Klebsiella sp.

substrate_name: sucrose


organism: Pseudomonas reinekei


substrate_name: squalene


organism: Thermomonospora curvata

substrate_name: maltose


substrate_name: isovaleryl-CoA (at 37 degrees Celsius)


substrate_name: ATP (at 37 degrees Celsius)


organism: Enterobacter sp. FMB-1


organism: Raoultella planticola


organism: Cupriavidus metallidurans


organism: Cupriavidus necator


organism: Serratia plymuthica


organism: Pseudomonas putida


substrate_name: maltopentaose


substrate_name: maltotetraose


organism: Thermus antranikianii

substrate_name: alpha,alpha-trehalose


organism: Meiothermus ruber


organism: Saccharolobus solfataricus


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: 4-nitrophenyl alpha-D-glucoside (at pH 6.8 and 37 degrees Celsius)


substrate_name: alpha-glucosyl fluoride (at pH 6.8 and 37 degrees Celsius)


organism: Thermus thermophilus


organism: Mycolicibacterium smegmatis


organism: Acetobacter aceti


organism: Streptomyces virginiae

substrate_name: butanoyl-CoA


substrate_name: isovaleryl-CoA


organism: Escherichia coli (strain K12)


organism: Klebsiella sp.


organism: Arthrobacter ramosus


organism: Escherichia coli


organism: Arthrobacter sp.

substrate_name: maltoheptaose


substrate_name: maltohexaose


substrate_name: Unknown


enzyme_display_name: tRNA pseudouridine(38-40) synthase

substrate_name: tRNA uridine39


organism: Pseudarthrobacter chlorophenolicus


organism: Pseudomonas sp.


substrate_name: trehalose


enzyme_display_name: aldose 1-epimerase

organism: Canis lupus familiaris

substrate_name: alpha-D-glucose


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

organism: Capsicum annuum

substrate_name: isopentenyl diphosphate


enzyme_display_name: adenylate cyclase


substrate_name: ATP


enzyme_display_name: UDP-arabinopyranose mutase

organism: Oryza sativa

substrate_name: UDP-beta-L-arabinopyranose


substrate_name: UDP-beta-L-arabinofuranose


organism: Chlamydomonas reinhardtii


organism: Oryza sativa subsp. japonica


enzyme_display_name: tRNA pseudouridine(32) synthase

substrate_name: tRNA uridine32


enzyme_display_name: beta-amyrin synthase

organism: Euphorbia tirucalli


enzyme_display_name: glucose-6-phosphate isomerase

organism: Carassius auratus

substrate_name: D-fructose 6-phosphate


enzyme_display_name: UniProt P21638

organism: Pseudomonas denitrificans (nom. rej.)

substrate_name: Hydrogenobyrinate


enzyme_display_name: alpha-amyrin synthase

organism: Malus domestica


enzyme_display_name: protostadienol synthase

organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)


substrate_name: UDP-L-arabinofuranose


substrate_name: UDP-L-arabinopyranose


organism: Eriobotrya japonica


enzyme_display_name: 2-hydroxyisobutanoyl-CoA mutase

organism: Kyrpidia tusciae DSM 2912


enzyme_display_name: dTDP-fucopyranose mutase

substrate_name: dTDP-alpha-D-fucopyranose


enzyme_display_name: precorrin-8X methylmutase


organism: Sinorhizobium sp


enzyme_display_name: ethylmalonyl-CoA mutase

organism: Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)


organism: Aquincola tertiaricarbonis


substrate_name: isovaleryl-CoA


enzyme_display_name: cucurbitadienol synthase

organism: Siraitia grosvenorii


substrate_name: isobutanoyl-CoA


substrate_name: butanoyl-CoA


substrate_name: butyryl-CoA


substrate_name: isobutyryl-CoA


organism: Cereibacter sphaeroides


organism: Escherichia coli


organism: Catfish


organism: Oryza sativa


substrate_name: Unknown


enzyme_display_name: leukotriene-C4 synthase

organism: Cavia porcellus

substrate_name: leukotriene A4 methyl ester


enzyme_display_name: protoporphyrin ferrochelatase

substrate_name: 2,4-disulfonic deuteroporphyrin


enzyme_display_name: cysteine-S-conjugate beta-lyase


enzyme_display_name: methionine gamma-lyase

organism: Citrobacter freundii

substrate_name: DL-homocysteine


enzyme_display_name: alanine racemase

organism: Clostridioides difficile

substrate_name: L-alanine


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

organism: Claviceps sp.

substrate_name: isopentenyl diphosphate


enzyme_display_name: methylaspartate mutase

organism: Clostridium cochlearium


enzyme_display_name: adenylate cyclase

substrate_name: ATP


organism: Clostridium perfringens


enzyme_display_name: D-psicose 3-epimerase

organism: [Clostridium] scindens

substrate_name: D-fructose


substrate_name: pivalyl-CoA


organism: Clostridium sp.


enzyme_display_name: lysine 2,3-aminomutase

substrate_name: L-Lys


organism: Clostridium subterminale


organism: Clostridium tetanomorphum


enzyme_display_name: steroid Delta-isomerase

organism: Comamonas testosteroni


enzyme_display_name: UDP-galactopyranose mutase

organism: Corynebacterium diphtheriae


enzyme_display_name: 2-hydroxyisobutanoyl-CoA mutase

organism: Aquincola tertiaricarbonis


enzyme_display_name: (-)-kolavenyl diphosphate synthase

organism: Salvia divinorum

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: UniProt P23971

organism: Bacillus subtilis


substrate_name: CoA


enzyme_display_name: UniProt B4EL89

organism: Burkholderia cenocepacia


substrate_name: phenylacetate


organism: Cucurbita pepo

substrate_name: S-adenosyl-L-methionine


organism: Cucurbita maxima


enzyme_display_name: Delta(3)-Delta(2)-enoyl-CoA isomerase

organism: Cucumis sativus


enzyme_display_name: peptidylprolyl isomerase

organism: Corynebacterium glutamicum


enzyme_display_name: muconolactone Delta-isomerase

organism: Cupriavidus necator


enzyme_display_name: benzoate--CoA ligase

organism: Anaerobic bacterium

substrate_name: benzoate


substrate_name: CoASH


enzyme_display_name: dicarboxylate--CoA ligase

organism: Rattus norvegicus


substrate_name: dodecanedioic acid


enzyme_display_name: phenylacetate--CoA ligase

organism: Penicillium chrysogenum


substrate_name: Butyric acid


substrate_name: trans-cinnamic acid


substrate_name: myristic acid


substrate_name: propionic acid


organism: Clarkia breweri


substrate_name: palmitate


substrate_name: stearate


substrate_name: Phenoxyacetate


substrate_name: caprylate


substrate_name: caproate


substrate_name: caprate


organism: Petunia hybrida


substrate_name: 4-coumaric acid


substrate_name: caffeic acid


substrate_name: ferulic acid


substrate_name: benzoic acid


substrate_name: CoA


substrate_name: geranylgeranyl diphosphate


organism: Geobacter metallireducens

substrate_name: benzoate


substrate_name: Unknown


enzyme_display_name: phytanate--CoA ligase

organism: Homo sapiens


organism: Thauera aromatica


enzyme_display_name: 4-hydroxybenzoate--CoA ligase

organism: Pseudomonas sp.


organism: Bos taurus

substrate_name: ATP (with (R)-lipoate as substrate)


organism: Rhodopseudomonas palustris

substrate_name: Coenzyme A; ATP; Benzoate


substrate_name: ATP; Coenzyme A; 4-Hydroxybenzoate


organism: Azoarcus evansii

substrate_name: ATP; Coenzyme A; Phenylacetic acid


substrate_name: butyrate


substrate_name: decanoate


substrate_name: hexanoate


substrate_name: laurate


substrate_name: phenylacetate


substrate_name: salicylate


substrate_name: cyclohexane carboxylate


substrate_name: caprate


substrate_name: caproate


substrate_name: caprylate


substrate_name: palmitate


substrate_name: Phenoxyacetate


substrate_name: stearate


substrate_name: stearate (when expressed in bacteria)


substrate_name: oleate (when expressed in bacteria)


substrate_name: linoleate (when expressed in bacteria)


substrate_name: arachidonate (when expressed in bacteria)


organism: Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

substrate_name: benzoate


substrate_name: ATP


substrate_name: CoA


organism: Arabidopsis thaliana

substrate_name: trans-cinnamate


substrate_name: p-coumarate


substrate_name: ferulate


substrate_name: caffeate


substrate_name: (R)-lipoate with ATP as phosphate donor


substrate_name: hexanoate


substrate_name: ATP (with hexanoate as substrate)


organism: Magnetospirillum sp.


substrate_name: tetradecanoate


enzyme_display_name: o-succinylbenzoate--CoA ligase

organism: Mycolicibacterium phlei


substrate_name: CoASH


organism: Anthoceros agrestis


organism: Aromatoleum evansii

substrate_name: PA (aerobically at 37 degrees Celsius)


substrate_name: CoA (aerobically at 37 degrees Celsius)


substrate_name: ATP (aerobically at 37 degrees Celsius)


substrate_name: Coenzyme A


substrate_name: phenylacetic acid


organism: Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)

substrate_name: ATP (at 50 degrees Celsius and pH 7.5)


substrate_name: CoA (at 50 degrees Celsius and pH 7.5)


substrate_name: PA (at 50 degrees Celsius and pH 7.5)


substrate_name: hexadecanoate (palmitate)


substrate_name: ATP


substrate_name: coenzyme A


organism: Mus musculus


substrate_name: octanoate


organism: Pseudomonas putida

substrate_name: ATP (at 30 degrees Celsius and pH 8.2)


substrate_name: CoA (at 30 degrees Celsius and pH 8.2)


substrate_name: PA (at 30 degrees Celsius and pH 8.2)


substrate_name: CoA


substrate_name: o-succinylbenzoate


organism: Bacillus subtilis


substrate_name: benzoate


organism: Burkholderia cenocepacia


substrate_name: phenylacetate


organism: Bacillus anthracis


substrate_name: Unknown


organism: Escherichia coli


organism: Paraburkholderia xenovorans


organism: Pseudomonas sp.


organism: Rhodopseudomonas palustris


substrate_name: reduced CoA


organism: Rattus norvegicus

substrate_name: phytanic acid


organism: Thermus thermophilus


enzyme_display_name: 2-furoate--CoA ligase


organism: Cupriavidus necator


enzyme_display_name: anthranilate--CoA ligase


organism: Thauera aromatica


enzyme_display_name: 4-chlorobenzoate--CoA ligase

organism: Alcaligenes sp. AL3007


enzyme_display_name: 3-hydroxybenzoate--CoA ligase

organism: Centaurium erythraea


enzyme_display_name: trans-feruloyl-CoA synthase

organism: Streptomyces sp

substrate_name: ferulate (at pH 7.0 and 30 degrees Celsius)


substrate_name: Coenzyme A; 4-Chlorobenzoate; ATP


enzyme_display_name: 3-hydroxypropionyl-CoA synthase

organism: Metallosphaera sedula

substrate_name: 3-Hydroxypropanoate; Coenzyme A; ATP


organism: Sulfolobus tokodaii

substrate_name: ATP; Coenzyme A; 3-Hydroxypropanoate


substrate_name: 3-Hydroxybenzoate; ATP; Coenzyme A


organism: Arabidopsis thaliana


organism: Oryza sativa subsp. japonica


substrate_name: ferulic acid


organism: Nicotiana tabacum


substrate_name: (E)-caffeate


substrate_name: (E)-ferulate


substrate_name: (E)-sinapate


substrate_name: ATP


substrate_name: CoA


substrate_name: Coenzyme A


organism: Pseudomonas sp. (strain CBS-3)


substrate_name: benzoate


substrate_name: Acrylate


substrate_name: propionate


organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: anthranilate


substrate_name: caffeate


substrate_name: ferulate


substrate_name: sinapate


substrate_name: cinnamate


organism: Pseudomonas sp.


enzyme_display_name: ribose-5-phosphate isomerase

organism: Cyberlindnera jadinii

substrate_name: D-ribose 5-phosphate


enzyme_display_name: UDP-glucose 4-epimerase

organism: Davallia divaricata

substrate_name: UDP-alpha-D-galactose


organism: Arthrobacter sp


enzyme_display_name: maltose alpha-D-glucosyltransferase

organism: Deinococcus radiodurans

substrate_name: maltose


enzyme_display_name: cellobiose epimerase

organism: Dictyoglomus thermophilum

substrate_name: cellobiose


organism: Dianthus caryophyllus

substrate_name: S-adenosyl-L-methionine


organism: Pyrobaculum neutrophilum


substrate_name: Toluate


organism: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)


substrate_name: ATP


organism: Mycobacterium tuberculosis

substrate_name: CoA


organism: Streptomyces carzinostaticus

substrate_name: 2-hydroxynaphthalene-1-carboxylic acid


substrate_name: Naphthalene-1-carboxylic acid


organism: Metallosphaera sedula


enzyme_display_name: 3-(methylthio)propionate--CoA ligase

organism: Ruegeria pomeroyi

substrate_name: Butyrate


substrate_name: propionate


substrate_name: Acrylate


substrate_name: Unknown


enzyme_display_name: 3-oxocholest-4-en-26-oate--CoA ligase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Mycolicibacterium smegmatis


substrate_name: 3-oxo-4-cholesten-26-oate (at pH 7.3 and 22 degrees Celsius)


organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)


enzyme_display_name: L-allo-isoleucine--holo-[CmaA peptidyl-carrier protein] ligase

organism: Pseudomonas savastanoi pv. glycinea

substrate_name: DL-coronamic acid (at pH 7.5 and 25 degrees Celsius)


organism: Candidatus Pelagibacter ubique


organism: Candidatus Pelagibacter communis


organism: Unknown prokaryotic organism

substrate_name: ferulate


organism: Ruegeria lacuscaerulensis (strain DSM 11314 / KCTC 2953 / ITI-1157)

substrate_name: MMPA


organism: Ruegeria lacuscaerulensis


organism: Pseudomonas syringae

substrate_name: L-allo-isoleucine


substrate_name: L-leucine


substrate_name: L-Valine


substrate_name: L-Isoleucine


substrate_name: CoA (with MMPA)


substrate_name: ATP (with MMPA)


substrate_name: butyrate


substrate_name: acrylate


enzyme_display_name: E1 ubiquitin-activating enzyme

organism: Homo sapiens

substrate_name: ATP


substrate_name: ubiquitin


substrate_name: ubiquitin carrier protein E2


substrate_name: Acrylate


substrate_name: propionate


substrate_name: Butyrate


organism: Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)


substrate_name: valerate


substrate_name: acetate


substrate_name: Oregon Green-labeled ubiquitin


substrate_name: L-allo-isoleucine (at pH 7.5 and 25 degrees Celsius)


substrate_name: L-leucine (at pH 7.5 and 25 degrees Celsius)


substrate_name: L-valine (at pH 7.5 and 25 degrees Celsius)


organism: Dictyoglomus turgidum

substrate_name: lactose


enzyme_display_name: D-psicose 3-epimerase

organism: Dorea sp. CAG:317

substrate_name: D-fructose


organism: Diospyros kaki

substrate_name: S-adenosyl-L-methionine


organism: Dirofilaria immitis


organism: Echinococcus granulosus

substrate_name: D-ribose 5-phosphate


substrate_name: L-allo-isoleucine


substrate_name: L-valine


substrate_name: L-leucine


organism: Mycobacterium tuberculosis


organism: Dyadobacter fermentans


enzyme_display_name: UniProt Q8TBC4

substrate_name: ATP


substrate_name: diphosphate


enzyme_display_name: L-firefly luciferin--CoA ligase

organism: Zophobas atratus

substrate_name: L-firefly luciferin


organism: Aquatica lateralis

substrate_name: Ketoprofen


organism: Photinus pyralis


enzyme_display_name: (hydroxyamino)benzene mutase

organism: Ectopseudomonas oleovorans

substrate_name: (hydroxylamino)benzene


organism: Enterobacter cloacae

substrate_name: N-acetylglucosamine 6-phosphate


organism: Pseudomonas aeruginosa (strain UCBPP-PA14)

substrate_name: L-cysteine


enzyme_display_name: UniProt P10378

organism: Escherichia coli


organism: Pseudomonas syringae pv. syringae

substrate_name: L-serine


substrate_name: L-threonine


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: MbtL-holo


organism: Pseudomonas aeruginosa

substrate_name: L-Cysteine


enzyme_display_name: thioglycine synthase

organism: Methanosarcina acetivorans

substrate_name: RLGFFGFDLQD


organism: Streptomyces coelicolor

substrate_name: L-proline


organism: Bacillus cereus


substrate_name: L-alanine


substrate_name: D-Alanine


enzyme_display_name: malonate--CoA ligase

organism: Rhizobium leguminosarum


substrate_name: malonate


substrate_name: CoA


substrate_name: methylmalonate


substrate_name: ATP


enzyme_display_name: indoleacetate--CoA ligase

organism: Aromatoleum aromaticum

substrate_name: phenyl acetate


substrate_name: 2-naphthyl acetate


organism: Methanocaldococcus jannaschii

substrate_name: GGRLGFYGYDLQD


organism: Escherichia coli (strain K12)

substrate_name: D-pantetheine (at pH 7.8 and 25 degrees Celsius)


substrate_name: salicylate


substrate_name: holo-EntB (at pH 8.8 and 37 degrees Celsius)


organism: Arabidopsis thaliana

substrate_name: Unknown


organism: Bradyrhizobium japonicum


organism: Vibrio cholerae


organism: Amycolatopsis mediterranei

substrate_name: benzoate


substrate_name: hexanoic acid


substrate_name: decanoic acid


substrate_name: lauric acid


substrate_name: palmitic acid


organism: Pseudomonas fluorescens

substrate_name: L-proline


organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)

substrate_name: D-alanine


substrate_name: CoA


substrate_name: malonate


organism: Aromatoleum aromaticum (strain DSM 19018 / LMG 30748 / EbN1)

substrate_name: indoleacetate


substrate_name: phenylacetate


substrate_name: ATP (in the presence of 0.6 mM indoleacetate)


substrate_name: CoA (in the presence of 0.6 mM indoleacetate)


substrate_name: L-serine


substrate_name: ATP


substrate_name: O-acetyl-L-serine


substrate_name: L-beta-chloroalanine


substrate_name: S-methyl-L-cysteine


substrate_name: malonate (at pH 7.5)


organism: Escherichia coli


substrate_name: salicylate


enzyme_display_name: E1 NEDD8-activating enzyme

organism: Homo sapiens


substrate_name: ubiquitin


substrate_name: 2-hydroxybenzoic acid


substrate_name: 2,5-dihydroxybenzoic acid


substrate_name: 2,3-Dihydroxybenzoic acid


substrate_name: 2,4-dihydroxybenzoic acid


substrate_name: diphosphate


organism: Bacillus subtilis

substrate_name: Unknown


substrate_name: malonate


substrate_name: D-Ala


enzyme_display_name: glutamate racemase

organism: Enterococcus faecalis

substrate_name: D-glutamate


organism: Dinoroseobacter shibae


organism: Bacillus cereus


organism: Enterococcus faecium

substrate_name: L-glutamate / D-glutamate


enzyme_display_name: alanine racemase

substrate_name: D-alanine


organism: Enterocloster bolteae

substrate_name: D-tagatose


enzyme_display_name: dTDP-4-dehydrorhamnose 3,5-epimerase


enzyme_display_name: UDP-glucose 4-epimerase


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-galactose


enzyme_display_name: chorismate mutase


enzyme_display_name: L-arabinose isomerase

substrate_name: D-galactose


enzyme_display_name: bisphosphoglycerate mutase

organism: Equus caballus

substrate_name: Glycerate 1,3-bisphosphate


enzyme_display_name: glucuronate isomerase

substrate_name: D-tagaturonate


enzyme_display_name: arabinose-5-phosphate isomerase

substrate_name: D-arabinose 5-phosphate


substrate_name: D-glucuronate


enzyme_display_name: S-ribosylhomocysteine lyase

substrate_name: S-ribosylhomocysteine


enzyme_display_name: tRNA pseudouridine(32) synthase

substrate_name: tRNA uridine32


enzyme_display_name: aspartate-ammonia ligase

organism: Lactiplantibacillus plantarum

substrate_name: ATP


substrate_name: L-Asp


enzyme_display_name: glutamine synthetase

organism: Methylococcus capsulatus

substrate_name: ADP


enzyme_display_name: UniProt P12425


enzyme_display_name: lactoylglutathione lyase


enzyme_display_name: tRNA pseudouridine(13) synthase

substrate_name: tRNA uridine13


substrate_name: UDP-GlcNAc


enzyme_display_name: lysine 2,3-aminomutase

substrate_name: L-Lys


enzyme_display_name: glutamate racemase

substrate_name: L-glutamate


organism: Arabidopsis thaliana


substrate_name: L-Glu


enzyme_display_name: isochorismate synthase

substrate_name: Unknown


enzyme_display_name: glutamate--ethylamine ligase

substrate_name: L-cysteine


substrate_name: ethylamine


organism: Clarias batrachus


substrate_name: hydroxylamine


organism: Sphagnum fallax


organism: Xylanibacter ruminicola


substrate_name: L-glutamine


organism: Oryza sativa Japonica Group


substrate_name: NH3; L-Glutamate; ATP


substrate_name: ATP; L-Glutamate; NH3


substrate_name: NH3; ATP; L-Glutamate


organism: Camellia sinensis


organism: Beta vulgaris


organism: Bradyrhizobium japonicum


enzyme_display_name: aspartate--ammonia ligase (ADP-forming)

organism: Solanum tuberosum


organism: Hordeum vulgare


organism: Spinacia oleracea


organism: Senna obtusifolia


enzyme_display_name: NAD(+) synthase

organism: Herbaspirillum seropedicae


organism: Zea mays


organism: Exiguobacterium sp.


organism: Mycobacterium tuberculosis

substrate_name: deamido-NAD+

mutation_signature: recombinant truncated enzyme


substrate_name: ATP


substrate_name: glutamine


substrate_name: glutamate


substrate_name: ammonium


organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)

substrate_name: L-glutamate (at pH 7.8 and 60 degrees Celsius)


substrate_name: hydroxylamine (when a high concentration is used, at pH 7.8 and 60 degrees Celsius)


substrate_name: ATP (at pH 7.8 and 60 degrees Celsius)


substrate_name: L-glutamine (at pH 7.2 and 60 degrees Celsius)


substrate_name: ADP (at pH 7.2 and 60 degrees Celsius)


organism: Homo sapiens


organism: Methylococcus capsulatus

substrate_name: Glu


organism: Synechocystis sp.


enzyme_display_name: oxazoline synthase

organism: uncultured Prochloron sp. 06037A

substrate_name: [TruE2]-(L-amino acyl-L-cysteine)


enzyme_display_name: thiazoline synthase

substrate_name: [TruE2]-L-amino acyl-L-cysteine


organism: Anabaena azollae


organism: Bacillus subtilis


organism: Canis familiaris

substrate_name: L-Glutamate; ATP; NH3


organism: Escherichia coli

substrate_name: NH3; L-Glutamate; ATP


organism: Arabidopsis thaliana

substrate_name: ATP; L-Glutamate; NH3


substrate_name: ATP; NH3; L-Glutamate


substrate_name: Unknown


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Oryza sativa

substrate_name: L-Glutamate; NH3; ATP


organism: Sulfolobus acidocaldarius


organism: Trichormus azollae


organism: Triticum aestivum


substrate_name: L-Glutamine; Phosphate; ADP


organism: Hordeum vulgare


organism: Medicago truncatula

substrate_name: NH3; ATP; L-Glutamate


organism: Phaseolus vulgaris


organism: Pseudomonas taetrolens


substrate_name: L-Glutamate


organism: Exiguobacterium sp.

substrate_name: ADP


substrate_name: L-glutamine


enzyme_display_name: aspartate--ammonia ligase

organism: Leishmania donovani

substrate_name: L-aspartate


substrate_name: glutamine


organism: Methylovorus mays

substrate_name: methylamine


substrate_name: ethylamine


substrate_name: hydroxylamine


substrate_name: ammonia


substrate_name: glutamic acid (with methylamine as substrate)


substrate_name: ATP (with methylamine as substrate)


organism: Haloferax mediterranei

substrate_name: ATP


substrate_name: L-Glu


substrate_name: L-Gln


organism: Oryza sativa subsp. japonica

substrate_name: glutamate


substrate_name: ammonium


organism: Bifidobacterium pseudolongum


organism: Ruminococcus albus


substrate_name: L-Glutamate; ATP; NH3


organism: Zea mays


substrate_name: NH3; L-Glutamate; ATP


organism: Bacillus subtilis

substrate_name: ATP; Deamino-NAD+; NH4+


substrate_name: Ethylamine; L-Glutamate; ATP


organism: Providencia vermicola

substrate_name: ADP


substrate_name: L-glutamine


organism: Anabaena azollae


substrate_name: L-Glutamate


organism: Paracoccus denitrificans


organism: Skeletonema costatum


substrate_name: Glu


organism: Sulfolobus acidocaldarius


organism: Clostridium pasteurianum


substrate_name: hydroxylamine


substrate_name: Gln


organism: Nitrobacter winogradskyi


organism: Trichormus azollae

substrate_name: L-glutamate


organism: Trichinella spiralis


organism: Rattus norvegicus

substrate_name: L-glutamate (with 2 mM of Mn(2+))


organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

substrate_name: ATP


substrate_name: alpha-glutamate


organism: Rhizobium meliloti (strain 1021)


organism: Tuber borchii


organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)


organism: Bacillus anthracis

substrate_name: deamido-NAD+


organism: Bacillus subtilis (strain 168)

substrate_name: deamido-NAD


substrate_name: glutamine


substrate_name: ammonium


organism: Bacillus subtilis


organism: uncultured Prochloron sp. 06037A


organism: Pyrococcus sp.


organism: Mycobacterium tuberculosis


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: alpha-glutamine (at 37 degrees Celsius)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Geobacillus stearothermophilus


organism: Methanocaldococcus jannaschii


substrate_name: glutamate


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


organism: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)

substrate_name: manganese


organism: Phaseolus vulgaris


organism: Lupinus luteus

substrate_name: ADP


organism: Medicago truncatula


organism: [Bacillus] caldolyticus


organism: Drosophila melanogaster


organism: Bradyrhizobium japonicum


substrate_name: L-Gln


substrate_name: L-glutamine


organism: Escherichia coli


substrate_name: L-Glu


organism: Trypanosoma cruzi


substrate_name: Unknown


organism: Azospirillum brasilense


organism: Pseudomonas taetrolens


substrate_name: methylamine


substrate_name: ethylamine


organism: Camellia sinensis


substrate_name: L-glutamate


organism: Bifidobacterium bifidum


substrate_name: ATP


organism: Bifidobacterium breve


organism: Corynebacterium callunae


substrate_name: hydroxylamine


substrate_name: Gln


organism: Canis lupus familiaris


organism: Exiguobacterium sp.


enzyme_display_name: beta-amyrin synthase

organism: Lathyrus oleraceus


substrate_name: Glu


organism: Methanohalophilus portucalensis


organism: Mycobacterium tuberculosis


organism: Pyrococcus sp.


organism: Nicotiana plumbaginifolia


organism: Ligilactobacillus salivarius

substrate_name: L-aspartate


organism: Staphylococcus aureus


organism: Spinacia oleracea


organism: Rhodobacter capsulatus


organism: Sinorhizobium meliloti


enzyme_display_name: D-aspartate ligase

organism: Enterococcus faecalis


substrate_name: D-Aspartate


enzyme_display_name: trypanothione synthase

organism: Leishmania major

substrate_name: glutathione


substrate_name: glutathionylspermidine


substrate_name: spermidine


organism: Enterococcus hirae

substrate_name: D-Aspartate; Hydroxylamine; ATP


enzyme_display_name: glutathionylspermidine synthase

organism: Crithidia fasciculata


organism: Escherichia coli


organism: Mycobacterium smegmatis

substrate_name: GlcN-Ins; ATP; L-Cysteine


enzyme_display_name: 4-methyleneglutamate--ammonia ligase

organism: Arachis hypogaea


enzyme_display_name: glutamate--putrescine ligase

organism: Escherichia coli (strain K12)


organism: Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4)


substrate_name: MgADP-


substrate_name: Reduced glutathione; ATP; Spermidine


substrate_name: Reduced glutathione; Glutathionylspermidine; ATP


substrate_name: GlcN-Ins


substrate_name: L-Cysteine


organism: Trypanosoma cruzi (strain CL Brener)

substrate_name: glutathione with spermidine as cosubstrate


substrate_name: MgATP


substrate_name: aminopropylcadaverine


substrate_name: glutamate (at pH 8 and at 37 degrees Celsius)


substrate_name: ATP (at pH 8 and at 37 degrees Celsius)


substrate_name: putrescine (at pH 8 and at 37 degrees Celsius)


substrate_name: ATP


substrate_name: Glutathionylspermidine


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)

substrate_name: L-cysteine


substrate_name: glutathione


substrate_name: spermidine


substrate_name: Unknown


substrate_name: glutathionylspermidine


organism: Leishmania donovani


organism: Trypanosoma brucei


substrate_name: Spermidine


substrate_name: reduced glutathione


organism: Escherichia coli K-12

substrate_name: putrescine


substrate_name: L-glutamate


substrate_name: ATP (at pH 6.8)


substrate_name: glutathionylspermidine (at pH 7.5)


enzyme_display_name: UniProt P33221

substrate_name: formyl phosphate


substrate_name: acetyl phosphate


substrate_name: Carbamoyl phosphate


substrate_name: Reduced glutathione


substrate_name: gamma-L-Glu-L-Cys(S-methyl)-Gly


enzyme_display_name: 8-demethylnovobiocic acid synthase

organism: Streptomyces niveus


organism: Azospirillum brasilense

substrate_name: L-glutamine


organism: Mycolicibacterium smegmatis


substrate_name: ATP


organism: Trypanosoma cruzi


substrate_name: GSH


enzyme_display_name: prokaryotic ubiquitin-like protein ligase

organism: Mycobacterium tuberculosis


enzyme_display_name: beta-citrylglutamate synthase

organism: Mus musculus

substrate_name: N-acetyl-aspartylglutamate


organism: Corynebacterium glutamicum

substrate_name: [PanB]-L-lysine


substrate_name: [protein PanB]-L-lysine


enzyme_display_name: lipoate--protein ligase

substrate_name: Unknown


substrate_name: D,L-lipoic acid


substrate_name: magnesium ion


substrate_name: L-glutamate


substrate_name: citrate


organism: Escherichia coli

substrate_name: octanoic acid


substrate_name: ADP


substrate_name: acetyl phosphate


substrate_name: Carbamoyl phosphate


substrate_name: formyl phosphate


substrate_name: octanoyl-[CoA]


substrate_name: R-lipoic acid


substrate_name: ATP


substrate_name: apoH-protein


substrate_name: DL-lipoic acid


organism: Bacillus anthracis

substrate_name: deamido-NAD+


enzyme_display_name: glutamine synthetase

organism: Chlorella sorokiniana


organism: Francisella tularensis


substrate_name: deamido-NMN


organism: Medicago truncatula

substrate_name: L-Glu


substrate_name: formate


organism: Nocardia asteroides


substrate_name: Glu


organism: Homo sapiens


substrate_name: L-glutamate


organism: Escherichia coli (strain K12)

substrate_name: acetate (at pH 8)


organism: Ovis aries


organism: Staphylococcus aureus


organism: Trypanosoma brucei

substrate_name: ATP; Reduced glutathione; Spermidine


organism: Streptococcus equinus


substrate_name: L-Asp


organism: Chlorella sp.

substrate_name: Unknown


organism: Trichormus variabilis


substrate_name: beta-Citryl-L-glutamate


organism: Columba sp.


organism: Bacillus subtilis


substrate_name: LplA acceptor peptide 2


enzyme_display_name: o-succinylbenzoate--CoA ligase


enzyme_display_name: peptidylprolyl isomerase

substrate_name: RNase T1


enzyme_display_name: L-arabinose isomerase

substrate_name: L-arabinose


enzyme_display_name: amino-acid racemase

substrate_name: D-homoserine


enzyme_display_name: sulfoquinovose isomerase

substrate_name: beta-sulfoquinovose


enzyme_display_name: UDP-glucose 4-epimerase

substrate_name: UDP-alpha-D-glucose


enzyme_display_name: L-ribulose-5-phosphate 4-epimerase

substrate_name: L-ribulose 5-phosphate


enzyme_display_name: UniProt Q2FV22

substrate_name: beta-Alanine


substrate_name: (R)-pantoate


enzyme_display_name: UniProt P0A6W9

substrate_name: L-alpha-aminobutyrate


substrate_name: L-cysteine


enzyme_display_name: UniProt P32477

organism: Saccharomyces cerevisiae

substrate_name: ATP


substrate_name: L-Glu


organism: Escherichia coli


substrate_name: L-glutamate


substrate_name: L-Cys


enzyme_display_name: Glutathione biosynthesis bifunctional protein GshAB

organism: Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 V/R)


substrate_name: ATP (in the reaction with gamma-GCS)


substrate_name: gamma-L-glutamyl-L-cysteine


substrate_name: glycine


enzyme_display_name: glutathione synthase

organism: Spinacia oleracea


organism: [Candida] boidinii

substrate_name: gamma-Glu-Cys


substrate_name: Gly


enzyme_display_name: UniProt P48637


enzyme_display_name: UniProt Q9M426

organism: Glycine max

substrate_name: beta-Ala


enzyme_display_name: UniProt P07862

substrate_name: D-alanine


enzyme_display_name: UniProt Q5SHZ3

organism: Thermus thermophilus


enzyme_display_name: UniProt Q2N4T5

organism: Helicobacter pylori


enzyme_display_name: UniProt Q5HEB7


organism: Streptococcus pyogenes


substrate_name: L-Lysine


organism: Streptococcus pyogenes serotype M1

substrate_name: L-lysine


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


enzyme_display_name: xylose isomerase

substrate_name: D-glucose


enzyme_display_name: arabinose-5-phosphate isomerase

substrate_name: D-ribulose 5-phosphate


enzyme_display_name: adenylate cyclase


substrate_name: UDP-N-acetyl-alpha-D-mannosamine


organism: Mycobacterium tuberculosis


substrate_name: Taurine


substrate_name: methylamine


substrate_name: cysteamine


substrate_name: ethylamine


substrate_name: glycolate


enzyme_display_name: UDP-N-acetylmuramate--L-alanine ligase

organism: Verrucomicrobium spinosum

substrate_name: L-alanine


substrate_name: UDP-N-acetyl-alpha-D-muramate


substrate_name: ATP


organism: Rattus norvegicus


organism: Lysinibacillus sphaericus

substrate_name: Lys


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


organism: Setaria cervi

substrate_name: Gly


substrate_name: beta-Alanine


substrate_name: Carbamate


substrate_name: D-Pantoate


enzyme_display_name: glutamate--cysteine ligase


substrate_name: ATP; L-alpha-Aminobutyrate; L-alpha-Methyl glutamate


substrate_name: ATP; L-Glutamate; 3-Cyano-L-alanine


substrate_name: L-Glutamate; L-alpha-Aminobutyrate; ATP


substrate_name: L-alpha-Aminobutyrate; ATP; L-alpha-Ethyl glutamate


substrate_name: D-Glutamate; ATP; L-alpha-Aminobutyrate


substrate_name: L-alpha-Aminobutyrate; ATP; L-Glutamate


organism: Synechocystis sp.

substrate_name: L-glutamate


substrate_name: L-cysteine


organism: Trypanosoma brucei


substrate_name: L-alpha-aminobutyrate


organism: Arabidopsis thaliana


organism: Allium cepa


organism: Pseudoalteromonas haloplanktis


enzyme_display_name: D-alanine--D-alanine ligase


substrate_name: D-alanine


substrate_name: ATP


substrate_name: gamma-L-glutamyl-L-cysteine


substrate_name: glycine


substrate_name: L-Glu


substrate_name: L-2-aminobutyric acid


organism: Actinobacillus succinogenes


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

substrate_name: L-lysine (at pH 9.4)


substrate_name: meso-diaminopimelate (at pH 9.4)


substrate_name: L-ornithine (at pH 9.4)


organism: Homo sapiens

substrate_name: L-Cys


enzyme_display_name: mandelate racemase

organism: Pseudomonas putida

substrate_name: (S)-Mandelate


organism: Plasmodium berghei


organism: Drosophila melanogaster


organism: Spinacia oleracea


organism: Streptococcus agalactiae


organism: Enterococcus faecalis

substrate_name: D-Alanine; ATP


organism: Enterococcus faecium

substrate_name: ATP; D-Alanine


organism: Escherichia coli


organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)

substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


substrate_name: (S)-lactate


substrate_name: Unknown


organism: Brassica juncea

substrate_name: L-cysteine


substrate_name: L-glutamate


organism: Mus musculus

substrate_name: L-Glutamate; ATP; L-alpha-Aminobutyrate


organism: Trypanosoma brucei


organism: Arabidopsis thaliana

substrate_name: gamma-Glu-L-Cys


organism: Streptococcus pyogenes


substrate_name: L-Alanine; UDP-N-acetylmuramate; ATP


organism: Pseudoalteromonas haloplanktis


organism: Synechocystis sp.


organism: Homo sapiens


organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)


substrate_name: ATP; L-Cysteine; L-Glutamate


organism: Ovis aries


organism: Pasteurella multocida


organism: Plasmodium berghei

substrate_name: gamma-L-Glu-L-Cys


substrate_name: (R)-Pantoate; ATP; beta-Alanine


organism: Mycobacterium tuberculosis

substrate_name: ATP; D-Pantoate


substrate_name: L-Glutamate; ATP; L-Cysteine


organism: Ascaris suum

substrate_name: L-aminobutanoate


substrate_name: L-aminobutyrate


organism: Actinobacillus succinogenes


substrate_name: ATP


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: beta-alanine


substrate_name: carbamate


substrate_name: methylamine


substrate_name: glycine


substrate_name: ethylamine


substrate_name: taurine


substrate_name: glycolate


substrate_name: gamma-aminobutyrate


substrate_name: gamma-amino-beta-hydroxybutyrate


organism: Escherichia coli

substrate_name: D-Alanine


enzyme_display_name: triose-phosphate isomerase

substrate_name: glycerone phosphate


substrate_name: L-glutamate


substrate_name: L-Cysteine


substrate_name: L-Cys


substrate_name: L-Glu


substrate_name: L-Glutamate


substrate_name: ATP


substrate_name: glutamate


substrate_name: cysteine


substrate_name: L-cysteine


organism: Schizosaccharomyces pombe

substrate_name: gamma-Glu-Cys


substrate_name: Gly


organism: Escherichia coli (strain K12)

substrate_name: UDP-N-acetyl-alpha-D-muramate


substrate_name: L-alanine


organism: Staphylococcus aureus

substrate_name: L-lysine


organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)

substrate_name: UDP-MurNAc


substrate_name: gamma-L-glutamyl-L-cysteine


substrate_name: glycine


substrate_name: magnesium


substrate_name: manganese


substrate_name: Asp


organism: Brucella abortus

substrate_name: beta-Alanine


substrate_name: (R)-pantoate


substrate_name: ATP


substrate_name: gamma-L-Glutamyl-L-cysteine


substrate_name: L-alpha-aminobutyrate


organism: Thermus thermophilus

substrate_name: D-Alanine


organism: Mycobacterium leprae


organism: Pseudoalteromonas haloplanktis


organism: Homo sapiens

substrate_name: CTP


substrate_name: L-ornithine


organism: Streptococcus agalactiae


substrate_name: L-Cys


substrate_name: L-Glu


substrate_name: Unknown


substrate_name: gamma-Glu-L-Cys


substrate_name: Gly


organism: Arabidopsis thaliana


organism: Myxococcus xanthus


substrate_name: gamma-L-glutamyl-L-cysteine


substrate_name: glycine


substrate_name: L-cysteine


substrate_name: L-glutamate


substrate_name: beta-Alanine


substrate_name: L-Ile


substrate_name: L-Vinylglycine


substrate_name: DL-propargylglycine


substrate_name: L-Val


substrate_name: L-Thr


substrate_name: 2-amino-n-butyric acid


substrate_name: UDP-N-acetyl-alpha-D-muramate


substrate_name: benzyl L-alaninate


substrate_name: methyl L-alaninate


substrate_name: ethyl L-alaninate


substrate_name: ATP


substrate_name: D-Ala


substrate_name: D-Phe


substrate_name: D-Met


substrate_name: D-norleucine


organism: Mus musculus


substrate_name: L-threonine


substrate_name: L-alanine


substrate_name: L-serine


substrate_name: L-methionine


substrate_name: glycine


substrate_name: L-valine


substrate_name: L-taurine


substrate_name: gamma-L-Glu-L-Cys


enzyme_display_name: ribose-5-phosphate isomerase

substrate_name: D-ribose 5-phosphate


substrate_name: L-cysteine


substrate_name: L-Glu


enzyme_display_name: glutathione synthase

substrate_name: gamma-Glu-Cys


substrate_name: L-Cys


substrate_name: ATP


substrate_name: Gly


substrate_name: gamma-L-Glu-aminobutanoate


organism: Actinobacillus pleuropneumoniae


substrate_name: L-glutamate


substrate_name: Unknown


substrate_name: gamma-L-glutamyl-L-cysteine


substrate_name: UDP-N-acetylmuramate


substrate_name: L-alanine


organism: Saccharomyces cerevisiae


organism: Pasteurella multocida


substrate_name: gamma-Glu-L-Cys


substrate_name: glycine


organism: Streptococcus thermophilus


substrate_name: L-alpha-aminobutyrate


organism: Escherichia coli


organism: Enterococcus faecalis

substrate_name: D-Ala


substrate_name: D-lactate


organism: Staphylococcus aureus

substrate_name: L-lysine


substrate_name: (R)-pantoate


substrate_name: beta-Alanine


enzyme_display_name: alanine racemase

organism: Streptomyces lavendulae


substrate_name: D-alanine


substrate_name: ATP


substrate_name: D-cycloserine


organism: Mycobacterium tuberculosis


substrate_name: L-serine


substrate_name: cysteine


substrate_name: CTP


substrate_name: L-Cys


substrate_name: L-Glu


substrate_name: L-Ala


substrate_name: beta-chloro-L-Ala


substrate_name: L-Ser


substrate_name: Gly


substrate_name: L-cysteine


substrate_name: L-glutamate


substrate_name: Unknown


organism: Nostoc sp.


organism: Plasmodium berghei


organism: [Candida] boidinii


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


substrate_name: L-Lys


substrate_name: gamma-L-Glu-L-Cys


organism: Agrobacterium tumefaciens


substrate_name: ATP


organism: Thermus thermophilus

substrate_name: D-alanine


organism: Arabidopsis thaliana


substrate_name: gamma-Glu-L-Cys


organism: Chlamydia trachomatis

substrate_name: L-alanine


substrate_name: L-serine


substrate_name: glycine


organism: Brassica juncea


substrate_name: cysteine


substrate_name: glutamate


substrate_name: beta-Alanine


substrate_name: (R)-pantoate


substrate_name: D-cycloserine


organism: Glycine max


substrate_name: beta-Ala


organism: Homo sapiens

substrate_name: gamma-glutamyl-alpha-aminobutyrate


substrate_name: Gly


substrate_name: D-pantoate


substrate_name: L-cysteine


organism: Rattus norvegicus

substrate_name: gamma-L-Glu-L-alpha-aminobutyrate


substrate_name: ATP


substrate_name: CTP


substrate_name: L-Cys


organism: Proteus mirabilis


substrate_name: L-Glu


organism: Streptococcus pyogenes


substrate_name: UDP-N-acetylmuramoyl-L-Ala-D-Glu


substrate_name: L-Lys


organism: Saccharomyces cerevisiae


organism: Staphylococcus aureus

substrate_name: UDP-N-acetylmuramate


substrate_name: L-Ala


organism: Xanthomonas campestris


substrate_name: L-glutamate


organism: Zea mays

substrate_name: gamma-Glu-L-Cys


organism: Triticum aestivum

substrate_name: glycine


substrate_name: beta-Ala


organism: Bacillus thuringiensis

substrate_name: (R)-pantoate


substrate_name: beta-Alanine


organism: Acinetobacter baumannii

substrate_name: D-alanine


organism: Escherichia coli


substrate_name: Gly


substrate_name: gamma-Glu-Cys


organism: Bacillus subtilis


organism: Corynebacterium glutamicum


organism: Helicobacter pylori


substrate_name: ATP


enzyme_display_name: sulfoquinovose mutarotase

organism: Herbaspirillum seropedicae


organism: Lotus japonicus


organism: Mycobacterium tuberculosis


enzyme_display_name: mannose 2-epimerase

organism: Runella slithyformis

substrate_name: beta-D-mannopyranose


enzyme_display_name: D-tagatose 6-phosphate 4-epimerase

organism: Agrobacterium fabrum

substrate_name: D-tagatose 6-phosphate


enzyme_display_name: mannuronan 5-epimerase

organism: Azotobacter vinelandii

substrate_name: Unknown


enzyme_display_name: tRNA pseudouridine(55) synthase

organism: Thermotoga maritima

substrate_name: tRNA uridine55


enzyme_display_name: fructoselysine 3-epimerase

organism: Escherichia coli (strain K12)

substrate_name: D-fructosyl-L-lysine


mutation_signature: pseudouridine synthase TruB with an 10-amino acid N-terminal truncation


organism: Nicotiana tabacum

substrate_name: L-Cys


organism: Lathyrus oleraceus


organism: Rattus norvegicus


substrate_name: L-alpha-aminobutyrate


organism: Staphylococcus aureus


organism: Thermus thermophilus


organism: Dyadobacter fermentans


organism: Bos taurus

substrate_name: (R)-beta-amino-iso-butyrate


organism: Escherichia coli


organism: Bacillus subtilis

substrate_name: L-Ala


organism: Onchocerca volvulus

substrate_name: L-glutamate


substrate_name: [alginate]-beta-D-mannuronate


organism: Enterococcus faecium

substrate_name: D-Ala


enzyme_display_name: Muconate cycloisomerase

organism: Rhodococcus opacus

substrate_name: cis,cis-muconate


enzyme_display_name: inositol-3-phosphate synthase

organism: Cyberlindnera jadinii

substrate_name: glucose 6-phosphate


enzyme_display_name: Inositol-3-phosphate synthase

organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: NAD (at 37 degrees Celsius and pH 7.2)


enzyme_display_name: chalcone isomerase

organism: Citrus sinensis


organism: Phaseolus vulgaris


enzyme_display_name: UniProt G4U3G8

organism: Deschampsia antarctica

substrate_name: isoliquiritigenin


substrate_name: naringenin chalcone


enzyme_display_name: Chloromuconate cycloisomerase

organism: Delftia acidovorans


enzyme_display_name: 23S rRNA pseudouridine(2457) synthase

substrate_name: 23S rRNA uridine2457


enzyme_display_name: phosphoribosylanthranilate isomerase


enzyme_display_name: D-alanine--D-alanine ligase


enzyme_display_name: glutathione synthase

substrate_name: ATP


substrate_name: D-pantoate


organism: Cephalocereus senilis

substrate_name: liquiritigenin


enzyme_display_name: muconate cycloisomerase


enzyme_display_name: D-lyxose ketol-isomerase

substrate_name: D-Lyxose


organism: Limnospira platensis

substrate_name: NAD+


organism: Synechocystis sp.

substrate_name: D-glucose 6-phosphate


organism: Gleichenia glauca


organism: Pinus ponderosa

substrate_name: D-Glucose 6-phosphate


organism: Physcomitrella appendiculatum


organism: Euglena gracilis


substrate_name: 1D-myo-Inositol 3-phosphate


organism: Cicer arietinum


organism: Bacillus sp. (in: firmicutes)


organism: Arthrospira platensis


organism: Taxus baccata


organism: Rhodococcus rhodochrous


organism: Lemna gibba


organism: Eubacterium ramulus


organism: Vigna radiata


enzyme_display_name: chloromuconate cycloisomerase

organism: Rhodococcus opacus


organism: Pseudomonas reinekei


organism: Medicago sativa

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Delftia acidovorans


organism: Arthrobacter sp.


organism: Homo sapiens


organism: Pseudomonas putida

substrate_name: cis,cis-Muconate


organism: Drosophila melanogaster


organism: Arabidopsis thaliana


substrate_name: NAD(+)


organism: Cupriavidus necator


enzyme_display_name: carboxy-cis,cis-muconate cyclase

organism: Neurospora crassa


organism: Corynebacterium glutamicum


organism: Citrus sinensis


organism: Rhodococcus erythropolis


substrate_name: Isoliquiritigenin


organism: Deschampsia antarctica


substrate_name: cis,cis-muconate


organism: Pseudomonas sp.


organism: Eubacterium ramulus


substrate_name: butein


organism: Hydrogenophaga intermedia


organism: Antrophyum callifolium


organism: Marchantia paleacea


organism: Selaginella moellendorffii


organism: Aspergillus niger


organism: Cutaneotrichosporon cutaneum


organism: Homo sapiens

substrate_name: NAD


organism: Saccharomyces cerevisiae


organism: Oryza sativa


organism: Medicago sativa

substrate_name: Naringenin chalcone


substrate_name: naringenin chalcone


organism: Arabidopsis thaliana


organism: Rattus norvegicus


organism: Trypanosoma brucei brucei

substrate_name: D-glucose 6-phosphate (at 37 degrees Celsius and pH 8.0)


organism: Vigna radiata


substrate_name: (+)-taxifolin


organism: Pseudomonas putida


organism: Odontosoria chusana


organism: Lindsaea orbiculata


organism: Acinetobacter calcoaceticus


substrate_name: Unknown


organism: Rhodococcus erythropolis


organism: Pseudomonas sp.


organism: Glycine max


organism: Adiantum capillus-veneris

substrate_name: isoliquiritigenin


organism: Agrobacterium tumefaciens


organism: Homo sapiens


substrate_name: glucose 6-phosphate


substrate_name: NAD+


organism: Oryza coarctata

substrate_name: D-glucose 6-phosphate


organism: Oryza sativa Japonica Group


substrate_name: muconolactone


organism: Archaeoglobus fulgidus


organism: Oryza sativa


organism: Pseudomonas reinekei


enzyme_display_name: dichloromuconate cycloisomerase

organism: Cupriavidus necator


enzyme_display_name: (+)-bornyl diphosphate synthase

organism: Tanacetum vulgare

substrate_name: geranyl diphosphate


substrate_name: (+)-(3S)-linalyl diphosphate


enzyme_display_name: cycloeucalenol cycloisomerase

organism: Zea mays

substrate_name: cycloeucalenol


enzyme_display_name: ent-copalyl diphosphate synthase

organism: Cucurbita maxima

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: alpha-pinene-oxide decyclase

organism: Nocardia sp.

substrate_name: alpha-Pinene oxide


organism: Medicago sativa


enzyme_display_name: copalyl diphosphate synthase

organism: Abies grandis


substrate_name: CPP (in presence of magnesium)


enzyme_display_name: terpentedienyl-diphosphate synthase

organism: Kitasatospora griseola


organism: Salvia officinalis


organism: Arabidopsis thaliana

substrate_name: (E,E,E)-geranylgeranyl diphosphate


organism: Phaeosphaeria sp.

substrate_name: copalyl diphosphate


organism: Talaromyces verruculosus

substrate_name: DMAPP (for prenyltransferase activity)


substrate_name: IPP (for prenyltransferase activity)


substrate_name: farnesyl diphosphate


substrate_name: Geranyl diphosphate


organism: Agrobacterium tumefaciens

substrate_name: Unknown


enzyme_display_name: inositol-3-phosphate synthase


enzyme_display_name: prosolanapyrone-III cycloisomerase

organism: Saccharopolyspora spinosa


enzyme_display_name: (-)-bornyl diphosphate synthase

organism: Blumea balsamifera


enzyme_display_name: UniProt P34808

organism: Caenorhabditis elegans

substrate_name: ATP


enzyme_display_name: aklanonic acid methyl ester cyclase

organism: Streptomyces galilaeus

substrate_name: nogalonic acid methyl ester


substrate_name: (-)-(3R)-linalyl diphosphate


organism: Alternaria solani

substrate_name: Prosolanapyrone II; O2


enzyme_display_name: halimadienyl-diphosphate synthase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Streptomyces peucetius


enzyme_display_name: lycopene beta-cyclase

organism: Paracoccus haeundaensis

substrate_name: lycopene


enzyme_display_name: microtubule-severing ATPase


organism: Tanacetum vulgare

substrate_name: geranyl diphosphate


substrate_name: (+)-(3S)-linalyl diphosphate


organism: Streptomyces sp.

substrate_name: geranylgeranyl diphosphate


organism: Homo sapiens

mutation_signature: Kinetic parameters shown are for full-length enzyme. N-terminally truncated spastin (residues 228-616)


enzyme_display_name: (+)-cis,trans-nepetalactol synthase

organism: Nepeta racemosa

substrate_name: cis-trans-nepetalactol (in the presence of NAD(+) at pH 8.0 and 25 degrees Celsius)


substrate_name: NAD(+) (in the presence of cis-trans-nepetalactol at pH 8.0 and 25 degrees Celsius)


substrate_name: H2O; ATP


organism: Mus musculus

substrate_name: ATP; H2O


organism: Citrullus lanatus

substrate_name: Lycopene


organism: Capsicum annuum

substrate_name: NADPH


substrate_name: Prosolanapyrone II


enzyme_display_name: (S)-beta-macrocarpene synthase

organism: Zea mays

substrate_name: farnesyl diphosphate


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


organism: Drosophila melanogaster

substrate_name: ATP


organism: Mycobacterium tuberculosis

substrate_name: (E,E,E)-geranylgeranyl diphosphate


substrate_name: Unknown


enzyme_display_name: phosphoribosylanthranilate isomerase

organism: Escherichia coli


enzyme_display_name: (+)-bornyl diphosphate synthase

organism: Cinnamomum burmanni


enzyme_display_name: glutamine synthetase

substrate_name: Gln


substrate_name: methyl aklanonate


enzyme_display_name: ADP-glyceromanno-heptose 6-epimerase

substrate_name: ADP-D-glycero-D-manno-heptose


substrate_name: formate


substrate_name: holo-[aryl-carrier protein EntB]


enzyme_display_name: isochorismate synthase

substrate_name: chorismate


enzyme_display_name: tRNA pseudouridine(38-40) synthase

substrate_name: tRNAHis guanidine36 uridine38 cytidine39


enzyme_display_name: chorismate mutase


enzyme_display_name: D-alanine--D-alanine ligase

substrate_name: D-serine


enzyme_display_name: peptidylprolyl isomerase


enzyme_display_name: L-rhamnose isomerase

substrate_name: L-rhamnulose


enzyme_display_name: cellobiose epimerase

organism: [Eubacterium] cellulosolvens

substrate_name: lactose


enzyme_display_name: adenylate cyclase

organism: Euglena gracilis


organism: Flavobacterium johnsoniae


enzyme_display_name: bisphosphoglycerate mutase

organism: Gallus gallus


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


organism: Ganoderma lucidum

substrate_name: alpha-D-glucose 1-phosphate


enzyme_display_name: methionine gamma-lyase

organism: Fusobacterium nucleatum subsp. nucleatum

substrate_name: L-cysteine


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: myosin ATPase

organism: Oryctolagus cuniculus

substrate_name: CTP


substrate_name: UTP


substrate_name: TTP


substrate_name: GTP


substrate_name: ITP


enzyme_display_name: proteasome ATPase

organism: Methanocaldococcus jannaschii


substrate_name: ATP

mutation_signature: Δ1


enzyme_display_name: dynein ATPase

organism: Saccharomyces cerevisiae


substrate_name: a dynein associated with a microtubule at position n


enzyme_display_name: plus-end-directed kinesin ATPase

organism: Dictyostelium discoideum

mutation_signature: truncated Kif3-342


mutation_signature: truncated Kif3-592


organism: Schizosaccharomyces pombe


mutation_signature: C-terminally truncated enzyme


organism: Neurospora crassa

substrate_name: phosphate


substrate_name: ADP


organism: Heliocidaris crassispina


organism: Bos taurus


organism: Lytechinus pictus


organism: Tetrahymena pyriformis


organism: Tetrahymena thermophila


substrate_name: Formycin triphosphate


organism: Hemicentrotus pulcherrimus


organism: Tripneustes gratilla


organism: Plasmodium berghei


enzyme_display_name: minus-end-directed kinesin ATPase

organism: Eremothecium gossypii


organism: Plasmodium falciparum


organism: Bifidobacterium longum subsp. infantis


organism: Rattus norvegicus


enzyme_display_name: chaperonin ATPase

organism: Pyrococcus furiosus


organism: Lathyrus oleraceus


organism: Saccharomyces cerevisiae


organism: Escherichia coli


substrate_name: K48-GREEN-TAIL polypeptide


organism: Dictyostelium sp.


organism: Caenorhabditis elegans


enzyme_display_name: inositol-3-phosphate synthase

organism: Bos taurus

substrate_name: D-glucose 6-phosphate


organism: Gallus gallus


organism: Lethocerus griseus


organism: Mammalia


organism: Oryctolagus cuniculus

substrate_name: ATP; H2O


organism: Lethocerus indicus


organism: Sus scrofa


organism: Homo sapiens


organism: Mus musculus


substrate_name: Unknown


organism: Drosophila melanogaster


organism: Thermoplasma acidophilum


organism: Acetivibrio thermocellus


organism: Schizosaccharomyces pombe


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: MgATP


organism: Escherichia coli


organism: Allochromatium vinosum


substrate_name: MgATP in complex with CIK1


enzyme_display_name: channel-conductance-controlling ATPase


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Dictyostelium discoideum


enzyme_display_name: microtubule-severing ATPase

organism: Caenorhabditis elegans

substrate_name: ATP (at 37 degrees Celsius and pH 8.8)


substrate_name: glutathione (in the presence of MgAMP-PNP)


organism: Danio rerio


organism: Methanococcus maripaludis


substrate_name: actin


organism: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)


organism: Acanthamoeba castellanii


enzyme_display_name: UniProt P11388


enzyme_display_name: UniProt P38935


substrate_name: methylanthraniloyl-ATP


organism: Saccharomyces cerevisiae


enzyme_display_name: RNA 3'-5' helicase

organism: West Nile virus


substrate_name: GTP


substrate_name: ITP


substrate_name: ribavirin triphosphate


enzyme_display_name: DNA 5'-3' helicase

organism: Severe acute respiratory syndrome-related coronavirus


substrate_name: dGTP


substrate_name: UTP


substrate_name: CTP


substrate_name: dCTP


substrate_name: dATP


substrate_name: dUTP


substrate_name: ATP


enzyme_display_name: DEAD-box RNA helicase


organism: Bacillus subtilis

substrate_name: RNA


organism: Hepacivirus hominis


substrate_name: dTTP


enzyme_display_name: DNA topoisomerase (ATP-hydrolyzing)

organism: Mycobacterium tuberculosis


enzyme_display_name: DNA 3'-5' helicase

substrate_name: Unknown


organism: Dengue virus


enzyme_display_name: RNA 5'-3' helicase

organism: Homo sapiens


organism: Thermochaetoides thermophila


organism: Saccharolobus solfataricus


organism: Pseudomonas phage EL


organism: Thermoanaerobacter brockii


organism: Enterobacteria phage T4


enzyme_display_name: myosin ATPase


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: ATP with dsDNA


organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)


organism: Drosophila melanogaster

substrate_name: ATP; negatively supercoiled circular DNA


substrate_name: ATP in helicase activity


organism: Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216)

substrate_name: 21-mer ssDNA substrate


organism: Dictyostelium discoideum


organism: Plasmodium falciparum (isolate 3D7)

substrate_name: dNTPs


substrate_name: ssDNA


organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)

substrate_name: ATP in presence of forked DNA with 40 bp lagging strand arm


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: ATP hydrolysis by TFIIH in the absence of RAD3/XPD ATPase activity


organism: Geobacillus stearothermophilus

substrate_name: ATP (for hydrolysis activity)


substrate_name: dATP (for hydrolysis activity)


substrate_name: CTP (for hydrolysis activity)


substrate_name: GTP (for hydrolysis activity)


substrate_name: dGTP (for hydrolysis activity)


substrate_name: dTTP (for hydrolysis activity)


substrate_name: 1,N6-ethenoadenosine 5'-triphosphate (for hydrolysis activity)


substrate_name: ATP


organism: Bacillus subtilis


organism: Bacillus subtilis (strain 168)


substrate_name: ATP (at 30 degrees Celsius)


substrate_name: dATP (at 30 degrees Celsius)


substrate_name: ATP with dsDNA


organism: Escherichia coli (strain K12)


organism: Homo sapiens


substrate_name: dATP


organism: Helicobacter pylori (strain ATCC 700392 / 26695)


substrate_name: UTP (using ssM13mp18 as DNA substrate)


organism: Leishmania major


organism: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)


substrate_name: DNA


organism: Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / KCTC 9307 / NBRC 14880 / R51)


organism: Mycobacterium tuberculosis


organism: Bos taurus


organism: Leishmania donovani


substrate_name: Unknown


organism: Saccharomyces cerevisiae


organism: Saccharolobus solfataricus


organism: Escherichia coli


organism: Bacillus anthracis


organism: Drosophila melanogaster


organism: Cereibacter sphaeroides


organism: Bacillus subtilis


enzyme_display_name: isobutyryl-CoA mutase

organism: Geobacillus kaustophilus

substrate_name: isobutyryl-CoA


organism: Aeropyrum pernix


enzyme_display_name: DNA topoisomerase

substrate_name: negatively supercoiled plasmid pXXZ06 DNA


organism: Geobacillus stearothermophilus


enzyme_display_name: L-arabinose isomerase

substrate_name: L-arabinose


substrate_name: D-galactose


enzyme_display_name: alanine racemase


enzyme_display_name: triose-phosphate isomerase

organism: Giardia duodenalis

substrate_name: D-glyceraldehyde 3-phosphate


enzyme_display_name: glucose-6-phosphate isomerase

substrate_name: fructose 6-phosphate


substrate_name: L-Ala


enzyme_display_name: chalcone isomerase

organism: Glycine max

substrate_name: liquiritigenin


enzyme_display_name: peptidylprolyl isomerase

organism: Halobacterium salinarum


organism: Helicobacter pylori

substrate_name: D-alanine


enzyme_display_name: D-sedoheptulose-7-phosphate isomerase

substrate_name: D-sedoheptulose 7-phosphate


organism: Heyndrickxia coagulans


enzyme_display_name: D-alanine--D-alanine ligase


enzyme_display_name: microtubule-severing ATPase

organism: Caenorhabditis elegans

substrate_name: ATP


enzyme_display_name: protein disulfide-isomerase

organism: Homo sapiens

substrate_name: RNase


enzyme_display_name: glutamate--cysteine ligase

substrate_name: L-alpha-aminobutyrate


enzyme_display_name: channel-conductance-controlling ATPase


enzyme_display_name: phosphoacetylglucosamine mutase

substrate_name: N-acetyl-alpha-D-glucosamine


enzyme_display_name: glutamine synthetase

substrate_name: L-Glutamine; ADP; Phosphate


enzyme_display_name: thromboxane-A synthase


enzyme_display_name: steroid Delta-isomerase

mutation_signature: truncated cytosolic enzyme DEALTA283-310


enzyme_display_name: UDP-N-acetylglucosamine 4-epimerase


enzyme_display_name: adenylate cyclase


enzyme_display_name: leukotriene-C4 synthase

substrate_name: leukotriene A4


enzyme_display_name: aldose 1-epimerase

substrate_name: alpha-D-glucose


substrate_name: leukotriene A4 methyl ester


enzyme_display_name: prostaglandin-E synthase


enzyme_display_name: lactoylglutathione lyase

substrate_name: (R)-S-lactoylglutathione


substrate_name: prostaglandin G2


enzyme_display_name: pancreatic ribonuclease

substrate_name: poly(C)


enzyme_display_name: prostaglandin-I synthase

substrate_name: prostaglandin H2


substrate_name: Unknown


enzyme_display_name: phosphomannomutase


enzyme_display_name: UniProt P0AGJ9


enzyme_display_name: UniProt P0A8M3

substrate_name: hydroxynorvaline


substrate_name: L-serine


substrate_name: L-threonine


enzyme_display_name: UniProt Q58597

organism: Methanocaldococcus jannaschii


enzyme_display_name: UniProt P07813

substrate_name: L-leucine


enzyme_display_name: UniProt Q9P2J5


substrate_name: L-isoleucine


enzyme_display_name: UniProt P09436

organism: Saccharomyces cerevisiae

substrate_name: AMP


enzyme_display_name: Isoleucine--tRNA ligase 2

organism: Pseudomonas fluorescens

substrate_name: isoleucine


substrate_name: ATP


substrate_name: cyclic 2',3'-cytidine monophosphate


enzyme_display_name: peptidylprolyl isomerase


enzyme_display_name: isopentenyl-diphosphate Delta-isomerase

substrate_name: isopentenyl diphosphate


enzyme_display_name: bisphosphoglycerate mutase


enzyme_display_name: DNA topoisomerase


enzyme_display_name: threonine--tRNA ligase

organism: Escherichia coli

substrate_name: tRNA(Thr); L-Threonine; ATP


substrate_name: ATP; tRNA(Thr); L-Threonine


substrate_name: tRNA(Thr); ATP; L-Threonine


enzyme_display_name: leucine--tRNA ligase

organism: Methanothermobacter thermautotrophicus

substrate_name: L-Leucine; tRNA(Leu); ATP


organism: Euglena gracilis

substrate_name: tRNALeu


substrate_name: L-Leu


enzyme_display_name: isoleucine--tRNA ligase


substrate_name: Unknown


organism: Brevundimonas vesicularis


organism: Pyrococcus horikoshii


organism: Pseudomonas putida


substrate_name: glutathione (at pH 7 and 25 degrees Celsius)


enzyme_display_name: lactoylglutathione lyase

substrate_name: glutathione-methylglyoxal


enzyme_display_name: tyrosine--tRNA ligase

substrate_name: L-tyrosine


substrate_name: L-leucine


organism: Saccharolobus solfataricus

substrate_name: L-serine


substrate_name: L-threonine


organism: Escherichia coli (strain K12)

substrate_name: azatyrosine


enzyme_display_name: diaminopimelate epimerase

organism: Haemophilus influenzae


organism: Acidithiobacillus ferrooxidans

substrate_name: ATP


substrate_name: tyrosine


organism: Bacillus subtilis

substrate_name: L-Isoleucine; tRNA(Ile); ATP


substrate_name: ATP; Isoleucine


substrate_name: ATP; L-Isoleucine; tRNA(Ile)


substrate_name: tRNA(Ile); L-Isoleucine; ATP


organism: Staphylococcus aureus

substrate_name: L-Isoleucine; ATP; tRNA(Ile)


organism: Aeropyrum pernix

substrate_name: tRNATyr


substrate_name: ATP; tRNA(Tyr); L-Tyrosine


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: tRNA(Tyr)


substrate_name: Unknown


enzyme_display_name: tryptophan--tRNA ligase

substrate_name: tRNA(Trp); ATP; L-Tryptophan


organism: Mus musculus

substrate_name: tRNA(Thr)


substrate_name: tRNA(Leu); L-Leucine; ATP


organism: Homo sapiens

substrate_name: L-Leucine; ATP; tRNA(Leu)


substrate_name: tRNA


organism: Thiobacillus ferrooxidans

substrate_name: tRNA(Tyr); L-Tyrosine; ATP


organism: Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)

substrate_name: L-threonine activation


organism: Burkholderia thailandensis


organism: Methanocaldococcus jannaschii


organism: Giardia duodenalis

substrate_name: L-leucine


substrate_name: ATP


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: L-serine activation


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)


organism: Saccharomyces cerevisiae


organism: Yersinia pestis


organism: Aquifex aeolicus

substrate_name: tRNALeu


substrate_name: L-isoleucyl-tRNALeu


organism: Pseudomonas putida


organism: Acanthamoeba polyphaga mimivirus


organism: Geobacillus stearothermophilus

substrate_name: L-Tyrosine; ATP


substrate_name: L-Tyrosine; ATP; tRNA(Tyr)


organism: Bacillus subtilis

substrate_name: L-Tryptophan; ATP; tRNA(Trp)


organism: Streptomyces griseus

substrate_name: AMP


organism: Pyrococcus horikoshii


substrate_name: tRNAGAGLeu


organism: Escherichia coli (strain K12)


organism: Homo sapiens

substrate_name: tRNALeuUUR


organism: Methanothermobacter thermautotrophicus

substrate_name: tRNA(Leu); ATP; L-Leucine


organism: [Mycoplasma] mobile

substrate_name: tRNALeu(GAG)


substrate_name: tRNAUAALeu


organism: Lacticaseibacillus casei


substrate_name: tRNAIle


organism: Escherichia coli


substrate_name: L-Leucine


substrate_name: L-Isoleucine


substrate_name: L-Tryptophan


substrate_name: L-leucine


organism: Pseudomonas fluorescens

substrate_name: ATP


substrate_name: L-tyrosine


substrate_name: L-tryptophan


organism: Methanocaldococcus jannaschii

substrate_name: L-threonine


substrate_name: L-serine


substrate_name: L-Tyrosine


organism: Mesomycoplasma mobile


substrate_name: L-Threonine


substrate_name: isoleucine


substrate_name: tyrosine


organism: Cricetulus griseus


organism: Mus musculus


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: leucine


substrate_name: tRNATrp


substrate_name: tRNALeu


substrate_name: Trp


organism: Mycobacterium tuberculosis


substrate_name: L-isoleucine


substrate_name: L-methionine


organism: Aquifex aeolicus


organism: Saccharomyces cerevisiae


substrate_name: tRNACUA


substrate_name: D-tyrosine


organism: Geobacillus stearothermophilus


substrate_name: ATP


substrate_name: L-tyrosine


organism: Acidithiobacillus ferrooxidans

mutation_signature: recombinant truncated mutant


substrate_name: L-tryptophan


substrate_name: K+


substrate_name: L-leucine


substrate_name: tRNALeu(UAA)


organism: Neisseria gonorrhoeae


substrate_name: L-threonine


substrate_name: Unknown


substrate_name: tRNAGAGLeu


substrate_name: hydroxynorvaline

mutation_signature: truncated enzyme DELTAN


substrate_name: L-serine


substrate_name: tRNALeu


organism: Bacillus subtilis

substrate_name: tRNATrp

mutation_signature: deletion 234-238 mutant


mutation_signature: deletion 108-122 mutant


substrate_name: tRNALeuUUR


substrate_name: tRNALeuCUN


organism: Homo sapiens

substrate_name: L-isoleucine


substrate_name: tRNATyr


substrate_name: ATP


substrate_name: adenosine 5'-O-(3-thiotriphosphate)


substrate_name: tubercidin 5'-triphosphate


substrate_name: 8-bromoadenosine 5'-triphosphate


substrate_name: tRNAIle


substrate_name: AMP


substrate_name: L-threonine


substrate_name: tRNALeu from Escherichia coli


substrate_name: L-leucine


substrate_name: L-methionine


substrate_name: L-norvaline


organism: Drosophila melanogaster


substrate_name: tyrosine


organism: Bos taurus

substrate_name: tRNATrp


substrate_name: Trp


organism: Escherichia coli


substrate_name: tRNALeu


substrate_name: diphosphate


substrate_name: Ile-tRNALeu


substrate_name: L-valine


substrate_name: L-isoleucine


substrate_name: ATP


substrate_name: L-tyrosine


substrate_name: tRNATyr


organism: Glycine max


substrate_name: L-tryptophan


organism: Lupinus luteus


mutation_signature: DELTAChcLeuRS (a C-terminal 89-amino acid truncated enzyme form)


organism: Pseudomonas aeruginosa


organism: Pseudomonas putida


substrate_name: L-threonine


organism: Rattus norvegicus


substrate_name: norvaline


substrate_name: L-leucine


organism: Triticum aestivum


organism: Aeropyrum pernix K1


substrate_name: tRNAArg


organism: Archaeoglobus fulgidus


substrate_name: Unknown


substrate_name: tRNAThr


mutation_signature: truncated enzyme core DELTAN truncated enzyme core DELTAN


substrate_name: L-oxonorvaline


substrate_name: tRNATrp


organism: Cricetulus griseus


mutation_signature: recombinant truncated mutant enzyme


substrate_name: ammonia


organism: Geobacillus stearothermophilus

substrate_name: diphosphate


substrate_name: AMP


organism: Haloferax volcanii


substrate_name: tRNASer mutant


substrate_name: tRNALeuUUR


substrate_name: tRNALeuCUN


substrate_name: tRNAGAGLeu


organism: Neurospora crassa

substrate_name: Leu


substrate_name: 8-bromoadenosine 5'-triphosphate


substrate_name: tyrosine


substrate_name: ATP


organism: Mycoplasma capricolum

substrate_name: L-serine


substrate_name: L-threonine


organism: Natrialba magadii

substrate_name: Natrialba magadii tRNALeu(CAA)


substrate_name: L-leucine


organism: Phaseolus vulgaris

substrate_name: L-Leu


substrate_name: tRNAThr


substrate_name: Formycin 5'-triphosphate


organism: Saccharomyces cerevisiae

substrate_name: tRNALeu


organism: Thermus thermophilus

substrate_name: L-isoleucine


substrate_name: Unknown


organism: Staphylococcus aureus


organism: Saccharomyces pastorianus

substrate_name: L-threonyl-tRNAThr


substrate_name: threonine


organism: Trypanosoma brucei


organism: Aquifex aeolicus


organism: Comamonas testosteroni


substrate_name: bovine tRNATrp(G73, wild-type)


organism: Cyberlindnera jadinii

substrate_name: Leu-tRNALeu


organism: Escherichia coli


mutation_signature: recombinant LS-domain deletion mutant


mutation_signature: Unknown


substrate_name: isoleucine


substrate_name: tRNAIle


organism: Homo sapiens

substrate_name: L-tyrosine


substrate_name: L-serine


substrate_name: L-threonine


substrate_name: tRNATrp


substrate_name: L-tryptophan


enzyme_display_name: protoporphyrin ferrochelatase


enzyme_display_name: DNA 3'-5' helicase

substrate_name: ATP


enzyme_display_name: guanylate cyclase

substrate_name: GTP


enzyme_display_name: DNA 5'-3' helicase


enzyme_display_name: channel-conductance-controlling ATPase


enzyme_display_name: E1 NEDD8-activating enzyme

substrate_name: diphosphate


enzyme_display_name: DNA topoisomerase (ATP-hydrolyzing)

substrate_name: Supercoiled DNA


enzyme_display_name: phenylpyruvate tautomerase


enzyme_display_name: cysteine-S-conjugate beta-lyase


substrate_name: A22G mutated tRNATyr transcript


enzyme_display_name: UDP-glucose 4-epimerase

substrate_name: UDP-galactose


enzyme_display_name: malonate--CoA ligase

substrate_name: malonate


enzyme_display_name: inositol-3-phosphate synthase

substrate_name: 2-deoxy-D-glucose 6-phosphate


enzyme_display_name: threonine--tRNA ligase

substrate_name: Unknown


enzyme_display_name: adenylate cyclase


enzyme_display_name: serine racemase

substrate_name: L-aspartate


enzyme_display_name: lactoylglutathione lyase

substrate_name: methylglyoxal


enzyme_display_name: leucine--tRNA ligase

substrate_name: tRNACAGLeu


substrate_name: UTP


enzyme_display_name: microtubule-severing ATPase


enzyme_display_name: prostaglandin-D synthase


enzyme_display_name: steroid Delta-isomerase


enzyme_display_name: glucose-6-phosphate isomerase


enzyme_display_name: UniProt Q9RHV9

substrate_name: L-lysine


enzyme_display_name: UniProt P00957

substrate_name: glycine


substrate_name: L-serine


substrate_name: L-alanine


enzyme_display_name: UniProt P56192

substrate_name: L-methionine


substrate_name: ATP