enzyme_display_name: protocatechuate decarboxylase

organism: Sedimentibacter hydroxybenzoicus


enzyme_display_name: ribulose-bisphosphate carboxylase

organism: Synura uvella

source_db: brenda

verification_status: unverified

kcat_display: Not reported

ki_display: Not reported

kcat_over_km_display: Not reported

mutation_signature: Unknown

source_license: CC BY 4.0

km_unit: mM


organism: Triticum aestivum


organism: Trachycarpus fortunei

substrate_name: D-ribulose 1,5-bisphosphate

km_display: Not reported


organism: Thiobacillus denitrificans


enzyme_display_name: UniProt Q6KZI8

organism: Picrophilus torridus

source_db: skid

protein_accession_database: UniProt

source_license: CC BY-NC-ND 4.0


enzyme_display_name: UniProt Q47098

organism: Escherichia coli

substrate_name: 3-deoxy-D-manno-oct-2-ulosonic acid


substrate_name: 4-hydroxy-2-oxopentanoic acid


enzyme_display_name: UniProt P76469


enzyme_display_name: UniProt O54288

organism: Saccharolobus solfataricus


enzyme_display_name: UDP-glucuronate decarboxylase

substrate_name: UDPglucuronate

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org)


organism: Amaranthus hybridus

substrate_name: D-Ribulose 1,5-bisphosphate; CO2; H2O

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org)

ki_unit: mM


organism: Echinochloa crus-galli


enzyme_display_name: diphosphomevalonate decarboxylase

organism: Arachis hypogaea

substrate_name: (R)-5-Diphosphomevalonate; ATP


enzyme_display_name: UniProt P0DTQ0

organism: Bacillus thuringiensis serovar kurstaki

substrate_name: 5-deoxy-D-ribulose 1-phosphate


organism: Glycine max

substrate_name: CO2; D-Ribulose 1,5-bisphosphate; H2O


organism: Portulaca oleracea

substrate_name: CO2; H2O; D-Ribulose 1,5-bisphosphate


organism: Zea mays


organism: Rhodospirillum rubrum


organism: Medicago sativa

substrate_name: H2O; D-Ribulose 1,5-bisphosphate; CO2


organism: Setaria italica


organism: Solanum lycopersicum


organism: Spinacia oleracea


organism: Sorghum bicolor


organism: Bos taurus


organism: Streptococcus pneumoniae


organism: Petroselinum crispum

substrate_name: H2O; CO2; D-Ribulose 1,5-bisphosphate


organism: Aphanizomenon flos-aquae


enzyme_display_name: isocitrate lyase

organism: Aspergillus nidulans

substrate_name: threo-Ds-isocitrate


enzyme_display_name: UniProt P0CT06

organism: Pyricularia oryzae

substrate_name: isocitrate


enzyme_display_name: UniProt Q9I0K4

organism: Pseudomonas aeruginosa


enzyme_display_name: UniProt Q05957

organism: Dianthus caryophyllus


substrate_name: oxalacetate


enzyme_display_name: UniProt P0A6L4

organism: Escherichia coli K-12

substrate_name: N-acetyl-D-mannosamine


substrate_name: pyruvate


enzyme_display_name: UniProt Q8NMD2

organism: Corynebacterium glutamicum

substrate_name: N-acetylneuraminate


enzyme_display_name: UniProt Q9CKB0

organism: Pasteurella multocida


organism: Citrullus lanatus


substrate_name: Ds-isocitrate


organism: Euglena gracilis

substrate_name: glyoxylate


substrate_name: succinate


organism: Pinus pinea


enzyme_display_name: N-acetylneuraminate lyase


organism: Turbatrix aceti


organism: Amaranthus caudatus

substrate_name: DL-isocitrate


organism: Papilio machaon


substrate_name: Unknown


organism: Candida brassicae


organism: Rattus norvegicus


organism: Pinus densiflora


substrate_name: acetyl-CoA


substrate_name: (2R,3S)-2,3-dimethyl malate

verification_status: verified


organism: Linum usitatissimum


organism: Aliivibrio salmonicida

substrate_name: N-acetyl-D-neuraminic acid

kcat_over_km_origin: calculated


organism: Limosilactobacillus antri

verification_status: corrected


organism: Escherichia coli (strain K12)

substrate_name: glyoxylate (at pH 7.3)

source_db: uniprot


substrate_name: succinate (at pH 7.3)


organism: Staphylococcus hominis


organism: Colwellia maris


organism: Aspergillus fumigatus


organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)

substrate_name: ManNAc (for the aldol condensation of ManNAc and pyruvate)


substrate_name: erythrose (for the aldol condensation of erythrose and pyruvate)


organism: Mycobacterium tuberculosis

substrate_name: isocitrate

source_license: CC BY 4.0; CC BY-NC-ND 4.0


organism: Latilactobacillus sakei


organism: Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)


organism: Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)


organism: Escherichia coli

substrate_name: N-Acetyl-D-neuraminate

source_license: CC BY 4.0; SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: glyoxylate (at pH 7 and 37 degrees Celsius)


substrate_name: succinate (at pH 7 and 37 degrees Celsius)


organism: Zea mays


organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

substrate_name: DL-threo-2-methylisocitrate (MICA) (at pH 7.5)


enzyme_display_name: hydroxymethylglutaryl-CoA lyase

organism: Homo sapiens


organism: Mediterraneibacter gnavus (strain ATCC 29149 / DSM 114966 / JCM 6515 / VPI C7-9)

substrate_name: N-acetylneuraminate


organism: Saccharolobus solfataricus


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


organism: Staphylococcus aureus


source_db: oed


substrate_name: N-Acetyl-L-neuraminate


substrate_name: Isocitrate


substrate_name: DL-isocitrate


organism: Escherichia coli (strain K12)

substrate_name: threo-D-isocitrate (at pH 7.3)


substrate_name: threo D-(s)-isocitrate


substrate_name: threo-DL-isocitrate (ICA) (at pH 6.8)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: threo-D(S)-isocitrate (at pH 7.0)


organism: Sulfolobus acidocaldarius

substrate_name: Unknown


organism: Limosilactobacillus antri

substrate_name: N-acetyl-D-mannosamine


substrate_name: pyruvate


organism: Acinetobacter calcoaceticus

substrate_name: threo-D-isocitrate


organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)


organism: Dianthus caryophyllus

substrate_name: (2R)-ethyl-(3S)-methyl malate


organism: Fomitopsis palustris


organism: Gloeothece citriformis PCC 7424


organism: Phycomyces blakesleeanus

substrate_name: Glyoxylate; Succinate


organism: Pseudomonas aeruginosa

substrate_name: isocitrate


organism: Neurospora crassa

substrate_name: glyoxylate


substrate_name: succinate


substrate_name: threo-Ds-isocitrate


organism: Staphylococcus carnosus


substrate_name: N-acetylneuraminate


substrate_name: Isocitrate


organism: Corynebacterium glutamicum


organism: Haloferax volcanii

substrate_name: D-isocitrate


organism: Hyphomicrobium methylovorum


substrate_name: D-Isocitrate


organism: Saccharomyces cerevisiae


organism: Homo sapiens


substrate_name: magnesium ion


organism: Clostridium perfringens (strain 13 / Type A)


organism: Escherichia coli

substrate_name: N-Acetyl-L-neuraminate


organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)


organism: Sus scrofa


organism: Sulfolobus acidocaldarius


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: HMG-CoA (at pH 6.7 and 37 degrees Celsius)


organism: Aspergillus nidulans


substrate_name: N-acetylneuraminic acid


substrate_name: N-acetyl-L-neuraminic acid


substrate_name: L-3-deoxy-manno-2-octulosonic acid


substrate_name: N-acetyl-D-neuraminic acid


substrate_name: D-3-deoxy-manno-2-octulosonic acid


organism: Clostridium perfringens


substrate_name: N-Formylneuraminic acid


substrate_name: N-Succinylneuraminic acid


substrate_name: N-glycolylneuraminic acid


substrate_name: N-Acetyl-7-O-acetylneuraminic acid


substrate_name: N-acetyl-4-O-acetylneuraminic acid


enzyme_display_name: citrate (pro-3S)-lyase

organism: Lacrimispora sphenoides

substrate_name: citrate


organism: Mycobacterium tuberculosis

substrate_name: threo-DL-Isocitrate


organism: Escherichia coli K-12

substrate_name: pyruvate


substrate_name: N-acetyl-D-mannosamine


substrate_name: N-acetylneuraminate


organism: Pseudomonas aeruginosa

substrate_name: isocitrate


organism: Pasteurella multocida


substrate_name: glyoxylate


substrate_name: succinate


organism: Colwellia psychrerythraea


organism: Pyricularia oryzae


organism: Staphylococcus aureus


organism: Staphylococcus carnosus


substrate_name: N-acetylneuraminic acid


organism: Mycoplasma sp.


organism: Escherichia coli


substrate_name: threo-Ds-isocitrate


substrate_name: DL-isocitrate


organism: Homo sapiens


substrate_name: Unknown


organism: Bos taurus


organism: Lactiplantibacillus plantarum


organism: Lupinus sp.


organism: Haemophilus influenzae


organism: Ricinus communis


substrate_name: hydroxymethylglutaryl-CoA


organism: Yarrowia lipolytica


organism: Anas sp.


organism: Candida tropicalis


organism: Pseudomonas sp. 'mevalonii'


organism: Bacillus sp. (in: firmicutes)


organism: Cucumis sativus


substrate_name: N-acetyl-neuraminic acid


organism: Clostridium perfringens


organism: Faecalispora sporosphaeroides


organism: Glycine max


organism: Staphylococcus aureus


organism: Helianthus annuus


organism: Acinetobacter calcoaceticus


organism: Homo sapiens

mutation_signature: deletion mutant Mut15


organism: Escherichia coli

substrate_name: N-glycolylneuraminic acid


organism: Klebsiella pneumoniae


organism: Lactiplantibacillus plantarum


organism: Paecilomyces variotii


organism: Mycobacterium tuberculosis


organism: Rubrivivax gelatinosus


organism: Vogesella indigofera


organism: Zea mays

substrate_name: Isocitrate


organism: Lupinus sp.


organism: Anas platyrhynchos


organism: Raphanus sativus


organism: Pseudomonas indigofera


organism: Geobacillus stearothermophilus


organism: Sus scrofa


organism: Rhodopseudomonas sp.


enzyme_display_name: 4-Hydroxy-2-oxoglutarate aldolase

organism: Rattus norvegicus


substrate_name: Pyruvic acid ethyl ester


substrate_name: pyruvic acid methyl ester


substrate_name: Pyruvaldehyde


substrate_name: acetaldehyde


enzyme_display_name: L-erythro-3-hydroxyaspartate aldolase

organism: Paracoccus denitrificans


enzyme_display_name: 4-hydroxy-2-oxoglutarate aldolase

organism: Homo sapiens


substrate_name: oxaloacetate


organism: Bos taurus


substrate_name: Oxaloacetate


substrate_name: pyruvate


organism: Pseudomonas straminea


enzyme_display_name: UniProt P9WFX2

substrate_name: chorismate


enzyme_display_name: UniProt P00900

organism: Serratia marcescens


enzyme_display_name: 2-methylisocitrate lyase, mitochondrial

organism: Yarrowia lipolytica (strain CLIB 122 / E 150)


substrate_name: magnesium chloride (MgCl(2))


substrate_name: cysteine


enzyme_display_name: UniProt Q2L887

organism: Aspergillus niger


enzyme_display_name: anthranilate synthase

organism: Ailanthus altissimus

substrate_name: Gln


organism: Ogataea henricii


enzyme_display_name: 2,3-dimethylmalate lyase


substrate_name: (R)-malate


substrate_name: Phosphonopyruvate


enzyme_display_name: (S)-citramalyl-CoA lyase

substrate_name: (3S)-citramalyl-CoA (for citramalyl-CoA lyase activity)


substrate_name: propionyl-CoA (for beta-methylmalate synthase)


substrate_name: acetyl-CoA (for malate synthase)


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)


substrate_name: anthranilate (with the dimeric form and for the phosphoribosyltransferase activity at pH 7.5)


substrate_name: phosphoribosylpyrophosphate (with the monomeric and dimeric forms and for the phosphoribosyltransferase activity at pH 7.5)


substrate_name: magnesium ion (with the monomeric and dimeric forms and for the phosphoribosyltransferase activity at pH 7.5)


substrate_name: glyoxylate (with acetyl-CoA as cosubstrate)


substrate_name: (S)-malyl-CoA (for malyl-CoA thioesterase activity)


enzyme_display_name: methylisocitrate lyase

organism: Escherichia coli (strain K12)

substrate_name: magnesium


organism: Oryza sativa


organism: Arabidopsis thaliana

substrate_name: L-Glutamine; Chorismate


organism: Escherichia coli

substrate_name: Chorismate; L-Glutamine


substrate_name: Chorismate


organism: Pseudomonas putida


organism: Saccharomyces cerevisiae


organism: Salmonella typhimurium


organism: [Bacillus] caldotenax

substrate_name: chorismate


organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

substrate_name: DL-threo-2-methylisocitrate (MICA) (at pH 7.5)


organism: Oryza sativa subsp. japonica

substrate_name: chorismate (for recombinant ASA1 and ASB1 proteins synthesized with the wheat germ cell-free system)


substrate_name: chorismate (for recombinant ASA2 and ASB1 proteins synthesized with the wheat germ cell-free system)


organism: Homo sapiens

substrate_name: Unknown


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


enzyme_display_name: UniProt P0A853

substrate_name: L-tryptophan


substrate_name: S-ethyl-L-cysteine


enzyme_display_name: tyrosine phenol-lyase

organism: Symbiobacterium sp.

substrate_name: L-tyrosine


substrate_name: S-(o-nitrophenyl)-L-cysteine


organism: Symbiobacterium thermophilum

substrate_name: S-methyl-L-Cys


organism: Pantoea agglomerans


substrate_name: S-methyl-L-cysteine


substrate_name: beta-chloro-L-alanine


substrate_name: L-Ser


enzyme_display_name: UniProt P31013

organism: Citrobacter freundii

substrate_name: S-Benzyl-L-cysteine


substrate_name: L-Tyr


enzyme_display_name: UniProt Q8ZNC4

organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: D-Lysine


substrate_name: D-ornithine


substrate_name: NH3; Chorismate


organism: Catharanthus roseus

substrate_name: L-Glutamine; Chorismate


organism: Aspergillus niger


substrate_name: chorismate


substrate_name: Gln


organism: Chloroflexus aurantiacus

substrate_name: (S)-malyl-CoA (for L-malyl-CoA lyase activity)


substrate_name: (2R,3S)-beta-methylmalyl-CoA (for beta-methylmalyl-CoA lyase activity)


substrate_name: acetyl-CoA (for L-malyl-CoA lyase activity)


substrate_name: propionyl-CoA (for beta-methylmalyl-CoA lyase activity)


substrate_name: glyoxylate (for beta-methylmalyl-CoA and L-malyl-CoA lyase activities)


organism: Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)

substrate_name: glyoxylate (for L-malyl-CoA formation)


substrate_name: acetyl-CoA (for L-malyl-CoA formation)


substrate_name: propionyl-CoA (for beta-methylmalyl-CoA formation)


substrate_name: beta-methylmalyl-CoA


organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

substrate_name: Unknown


organism: Escherichia coli (strain K12)

substrate_name: threo-2-methylisocitrate (a mixture of (2R,3S)- and (2S,3R)-2-methylisocitrate in presence of 2 mM magnesium at pH 7 and 30 degrees Celsius)


substrate_name: threo-D-isocitrate (at pH 6.8 and 37 degrees Celsius)


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

substrate_name: threo-D(S)-isocitrate (at pH 7.0)


enzyme_display_name: UniProt Q54764

organism: Synechococcus elongatus

substrate_name: n-Heptanal


enzyme_display_name: UniProt Q55688

organism: Synechocystis sp. PCC 6803

substrate_name: n-hexadecanal


organism: Escherichia coli

substrate_name: L-Tyr


substrate_name: L-Asp


substrate_name: L-Glu


enzyme_display_name: tryptophanase

organism: Porphyromonas gingivalis

substrate_name: L-Trp


substrate_name: S-methyl-L-cysteine


substrate_name: S-ethyl-L-cysteine


enzyme_display_name: 3-hydroxybenzoate synthase

organism: Lentzea aerocolonigenes

substrate_name: chorismate


organism: Prevotella intermedia


substrate_name: L-tryptophan


enzyme_display_name: 4-hydroxy-2-oxohexanoate aldolase

organism: Burkholderia xenovorans


organism: Aeromonas phenologenes


organism: Streptomyces conglobatus


enzyme_display_name: UniProt A0A0H2UN41

organism: Streptococcus pneumoniae

substrate_name: D-ribulose 5-phosphate


organism: Xylella fastidiosa


enzyme_display_name: (4S)-4-hydroxy-2-oxoglutarate aldolase

organism: Azotobacter vinelandii


organism: Paraburkholderia xenovorans


substrate_name: oxaloacetate


substrate_name: propionaldehyde


substrate_name: pyruvate


substrate_name: Butyraldehyde


substrate_name: acetaldehyde


organism: Citrobacter intermedius

substrate_name: Phe


substrate_name: Ser


substrate_name: Ala


substrate_name: L-m-Tyr


substrate_name: Tyr


substrate_name: KDPG


substrate_name: KDG


organism: Streptomyces hygroscopicus


organism: Escherichia coli (strain K12)


enzyme_display_name: (R)-citramalyl-CoA lyase

organism: Chloroflexus aurantiacus


organism: Pantoea agglomerans

substrate_name: L-tyrosine


organism: Symbiobacterium thermophilum

substrate_name: L-Tyr


organism: Thermus thermophilus


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Citrobacter freundii

substrate_name: S-ethyl-L-Cys


substrate_name: p-L-Tyr


enzyme_display_name: 3-hydroxy-D-aspartate aldolase

organism: Paracoccus denitrificans

substrate_name: Unknown


substrate_name: KHPB


substrate_name: Isobutyraldehyde


substrate_name: hexaldehyde


substrate_name: pentaldehyde


substrate_name: propionaldehyde


substrate_name: acetaldehyde


substrate_name: Butyraldehyde


substrate_name: oxaloacetate


organism: Proteus vulgaris

substrate_name: L-Tryptophan; H2O


substrate_name: L-Tryptophan


substrate_name: beta-chloro-L-alanine


substrate_name: S-Benzyl-L-cysteine


substrate_name: S-Ethyl-L-cysteine


substrate_name: S-Methyl-L-cysteine


substrate_name: S-o-Nitrophenyl-L-cysteine


substrate_name: S-ethyl-L-cysteine


substrate_name: S-methyl-L-cysteine


substrate_name: L-Serine


organism: Fusobacterium nucleatum subsp. nucleatum

substrate_name: L-Dopa


substrate_name: L-tyrosine


substrate_name: phenol


organism: Vibrio cholerae O1

substrate_name: L-tryptophan


organism: Paracoccus denitrificans (strain Pd 1222)

substrate_name: glyoxylate


substrate_name: glycine


substrate_name: D-threonine


substrate_name: pyruvate


enzyme_display_name: anthranilate synthase

substrate_name: chorismate (at pH 7.5)


substrate_name: glutamine (at pH 7.5)


substrate_name: glycolaldehyde


substrate_name: acetaldehyde


substrate_name: propionaldehyde


organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

substrate_name: magnesium


substrate_name: isocitrate


substrate_name: ammonia (at 37 degrees Celsius and at pH 7.6)


organism: Arabidopsis thaliana

substrate_name: chorismate


organism: Prevotella intermedia

substrate_name: S-ethyl-L-cysteine


substrate_name: S-methyl-L-cysteine


organism: Aspergillus nidulans


organism: [Bacillus] caldotenax


organism: Escherichia coli

source_license: SABIO-RK terms (free for academic use; see sabiork.h-its.org); CC BY-NC-ND 4.0


organism: Paraburkholderia xenovorans


enzyme_display_name: 2,3-dimethylmalate lyase

organism: Eubacterium barkeri


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: HMG-CoA (at pH 6.7 and 37 degrees Celsius)


organism: Pantoea agglomerans

substrate_name: catechol


organism: Streptomyces sp.


organism: Thermus thermophilus


organism: Citrobacter freundii

substrate_name: S-methyl-L-Cys


substrate_name: S-benzyl-L-Cys


substrate_name: S-(o-nitrophenyl)-L-Cys


substrate_name: L-Phe


substrate_name: L-Met


substrate_name: oxaloacetate


substrate_name: L-tyrosine


substrate_name: S-ethyl-L-Cys


substrate_name: S-(o-nitrophenyl)-L-cysteine


substrate_name: L-Dopa


substrate_name: S-Benzyl-L-cysteine


substrate_name: beta-chloro-L-alanine


substrate_name: D-Ala


substrate_name: S-benzoyl-L-Cys


substrate_name: L-Ser


substrate_name: L-Tyr


substrate_name: S-benzylcysteine


substrate_name: O-benzylserine


substrate_name: alpha,beta-diaminopropionic acid


substrate_name: S-ethylcysteine


substrate_name: O-methylserine


substrate_name: cysteine sulfinic acid


organism: Proteus vulgaris

substrate_name: Trp


substrate_name: S-methyl-L-Cys


substrate_name: S-ethyl-L-cysteine


substrate_name: beta-chloroalanine


substrate_name: S-o-nitrophenyl-L-Cys


substrate_name: L-tryptophan


substrate_name: Unknown


substrate_name: indole


substrate_name: Cys


substrate_name: pyruvate


substrate_name: L-Ser


substrate_name: S-ethyl-L-Cys


substrate_name: S-benzyl-L-Cys


organism: Daucus carota

substrate_name: chorismate


substrate_name: L-Gln


organism: Photobacterium profundum


substrate_name: L-Met


substrate_name: L-Phe


organism: Salmonella enterica


organism: Archaeoglobus fulgidus


organism: Providencia rettgeri

substrate_name: L-Cys


substrate_name: S-methyl-L-Cys


organism: Aspergillus fumigatus

substrate_name: methylisocitrate


organism: Fusobacterium nucleatum subsp. nucleatum

substrate_name: phenol


substrate_name: L-Dopa


substrate_name: L-tyrosine


substrate_name: pyrocatechol


organism: Oryza sativa


substrate_name: Unknown


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Saccharolobus solfataricus


organism: Streptomyces venezuelae


substrate_name: L-glutamine


organism: Escherichia coli


substrate_name: L-tryptophan


organism: Thermococcus kodakarensis


organism: Pseudomonas putida


substrate_name: Gln


organism: Vibrio cholerae O1

substrate_name: S-Benzyl-L-cysteine


substrate_name: S-methyl-L-cysteine


organism: Citrobacter freundii


substrate_name: S-benzyl-L-Cys


organism: Claviceps sp.

substrate_name: chorismate


organism: Cupriavidus necator


substrate_name: glutamine


substrate_name: S-(o-nitrophenyl)-L-cysteine


substrate_name: glyoxylate


substrate_name: pyruvate


organism: Ruta graveolens


organism: Proteus vulgaris


organism: Aeromonas hydrophila

substrate_name: L-Trp


organism: Aspergillus nidulans


substrate_name: D-Ala


organism: Morganella morganii


organism: Mycobacterium tuberculosis


organism: Paenibacillus alvei


substrate_name: S-methyl-L-Cys


substrate_name: L-tyrosine


organism: Paracoccus denitrificans


organism: Providencia rettgeri


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Serratia marcescens


substrate_name: oxindolyl-L-alanine


organism: Symbiobacterium thermophilum


organism: Zea mays

substrate_name: NH3; Chorismate


organism: Salmonella typhimurium


organism: Yarrowia lipolytica


enzyme_display_name: UniProt Q54735

organism: Synechocystis sp. PCC 6803 / Kazusa


enzyme_display_name: UniProt C0QRB5

organism: Persephonella marina


enzyme_display_name: UniProt Q16790

organism: Homo sapiens


enzyme_display_name: UniProt Q9ULX7


enzyme_display_name: UniProt P05042

organism: Escherichia coli

substrate_name: (S)-malate


substrate_name: (S,S)-Tartrate


enzyme_display_name: aconitate hydratase

organism: Saccharomycopsis lipolytica

substrate_name: cis-aconitate


substrate_name: isocitrate


substrate_name: 2-methyl cis-aconitate


substrate_name: methylisocitrate


enzyme_display_name: carbonic anhydrase

organism: Acipenser gueldenstaedtii


substrate_name: Unknown


enzyme_display_name: fumarate hydratase

organism: Euglena gracilis

substrate_name: fumarate


organism: Methanothermobacter thermautotrophicus


organism: Sinapis alba


substrate_name: citrate


organism: Leishmania chagasi


substrate_name: Fumarate; H2O


substrate_name: L-Malate


substrate_name: H2O; Fumarate


organism: Brucella suis


organism: Porphyromonas gingivalis


organism: Bacillus cereus

substrate_name: Isocitrate


substrate_name: Citrate


enzyme_display_name: arabinonate dehydratase

organism: Herbaspirillum huttiense

substrate_name: L-fuconate


substrate_name: D-idonate


substrate_name: L-xylonate


organism: Bos taurus

substrate_name: 4-nitrophenyl acetate


organism: Pelotomaculum thermopropionicum

substrate_name: (S)-malate


organism: Conticribra weissflogii


organism: Corynebacterium flavescens


organism: Elephas trogontherii

substrate_name: p-nitrophenyl acetate


organism: Macropus eugenii desmarest


organism: Acer pseudoplatanus

substrate_name: cis-aconitate


organism: Methanosarcina thermophila


organism: Sander vitreus


organism: Mus musculus


organism: Solanum tuberosum


organism: Stylophora pistillata


organism: Sulfurihydrogenibium yellowstonense


organism: Tectona grandis


organism: Rattus norvegicus


organism: Helicobacter pylori


substrate_name: isocitrate


organism: Rattus rattus


organism: Teladorsagia circumcincta


organism: Escherichia coli


organism: Escherichia coli (strain K12)


substrate_name: enol-oxaloacetate


organism: Schistosoma mansoni

substrate_name: L-malate (at pH 7.5 and in the presence of 150 mM KCl)


substrate_name: fumarate (at pH 7.5 and in the presence of 150 mM KCl)


enzyme_display_name: cyclopenase

organism: Aspergillus nidulans

substrate_name: (-)-cyclopenine


organism: Arabidopsis thaliana


substrate_name: Fumarate; H2O


organism: Corynebacterium glutamicum


organism: Homo sapiens


organism: Cryptococcus neoformans


substrate_name: H2O; CO2


organism: Enterobacter sp. B13

substrate_name: Unknown


organism: Gyrodactylus salaris


enzyme_display_name: 3'-dehydrocarminate deglycosidase

organism: Microbacterium sp


organism: Candida albicans

substrate_name: CO2; H2O


organism: Chionodraco hamatus


organism: Coccomyxa sp.


organism: Halothiobacillus neapolitanus


organism: Lathyrus oleraceus


organism: Malassezia globosa


organism: Malassezia pachydermatis


organism: Malassezia restricta


organism: Methanosarcina thermophila


organism: Rattus norvegicus

substrate_name: H2O; Fumarate


organism: Escherichia coli

substrate_name: H2O; cis-Aconitate


organism: Helicobacter pylori


organism: Sulfolobus acidocaldarius


organism: Micropterus salmoides


organism: Mus musculus


organism: Nakaseomyces glabratus

substrate_name: histamine


organism: Neisseria gonorrhoeae


organism: Microbacterium sp


organism: Persephonella marina


organism: Plasmodium falciparum

mutation_signature: truncated form PfCA1 / truncated form PfCA1


mutation_signature: truncated form PfCA1


mutation_signature: truncated mutant PfCA1


organism: Spinacia oleracea


organism: Arabidopsis thaliana

substrate_name: fumarate (at pH 8.0)


substrate_name: (S)-malate (at pH 8.0)


substrate_name: fumarate (at pH 7.7)


substrate_name: (S)-malate (at pH 7.7)


substrate_name: Dihydrogen carbonate


organism: Sulfurihydrogenibium azorense


organism: Sulfurihydrogenibium sp. YO3AOP1


organism: Trematomus bernacchii


organism: Leishmania major


organism: Synechocystis sp. 6803

substrate_name: (S)-malate


substrate_name: fumarate


organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)

substrate_name: cis-aconitate (at pH 8)


substrate_name: citrate (at pH 8)


substrate_name: isocitrate (at pH 8)


organism: Dioscorea japonica

substrate_name: dehydroascorbate (DHA) (at ph 7.0 and 30 degrees Celsius)


substrate_name: sodium bicarbonate (at ph 7.1 and 4 degrees Celsius)


organism: Halothiobacillus neapolitanus (strain ATCC 23641 / DSM 15147 / CIP 104769 / NCIMB 8539 / c2)


organism: Rattus norvegicus


organism: Homo sapiens


substrate_name: L-Malate


substrate_name: fumarate (at pH 8.5)


organism: Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)

substrate_name: CO(2) at pH 7.5, 25 degrees Celsius, for N-terminal 209 residue fragment


organism: Escherichia coli

substrate_name: L-malate


organism: Escherichia coli (strain K12)

substrate_name: D-tartrate


substrate_name: Unknown


organism: Saccharomyces cerevisiae

substrate_name: Fumarate; H2O


organism: Sus scrofa


organism: Mycobacterium smegmatis

substrate_name: H2O; cis-Aconitate


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Rhizopus arrhizus


substrate_name: Citrate


substrate_name: D-Isocitrate


substrate_name: 4-nitrophenyl acetate


substrate_name: fumarate (in anaerobic conditions)


substrate_name: (S)-malate (in anaerobic conditions)


organism: Corynebacterium glutamicum


substrate_name: Fumarate


organism: Plasmodium falciparum

substrate_name: mesaconate


substrate_name: (S)-malate


substrate_name: fumarate


substrate_name: Isocitrate


organism: Arabidopsis thaliana

substrate_name: L-Malate


organism: Sulfolobus acidocaldarius


substrate_name: cis-aconitate


organism: Cyanidioschyzon merolae


organism: Helianthus annuus

substrate_name: L-malate


organism: Thermosynechococcus vestitus


organism: Candida albicans (strain SC5314 / ATCC MYA-2876)


organism: Aspergillus nidulans


organism: Synechocystis sp. PCC 6803

substrate_name: citrate


substrate_name: isocitrate


organism: Homo sapiens


organism: Malassezia restricta


organism: Petroselinum crispum


organism: Methanosarcina thermophila


organism: Escherichia coli


organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

substrate_name: (-)-Cyclopeptin


organism: Helicobacter pylori


organism: Escherichia coli (strain K12)

substrate_name: D-tartrate


organism: Pisum sativum


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Sus scrofa


organism: Rattus norvegicus


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

substrate_name: malate (at pH 7.5 and at 70 degrees Celsius)


organism: Trypanosoma brucei brucei


organism: Saccharolobus solfataricus

substrate_name: D-Arabinonate


organism: Leishmania major


organism: Rhizopus arrhizus


organism: Homo sapiens


substrate_name: L-threo-chloromalate


substrate_name: fluorofumarate


substrate_name: chlorofumarate


substrate_name: L-Tartrate


organism: Mus musculus


substrate_name: Unknown


organism: Escherichia coli O157:H7

substrate_name: mesaconate


substrate_name: (S)-malate


substrate_name: fumarate


substrate_name: (S)-citramalate


organism: Escherichia coli K-12


organism: Paraburkholderia xenovorans


organism: Bos taurus

substrate_name: cis-aconitate


substrate_name: methylisocitrate


substrate_name: citrate


organism: Microbacterium sp. 5-2b


organism: Bacillus subtilis

substrate_name: 4-nitrophenyl acetate


organism: Bacteria


substrate_name: L-malate


organism: Colwellia psychrerythraea


organism: Escherichia coli


substrate_name: acetylene dicarboxylate


organism: Corynebacterium glutamicum


substrate_name: isocitrate


organism: Drosophila melanogaster


organism: Entamoeba histolytica


organism: Nostoc commune


organism: Oryctolagus cuniculus


organism: Pseudoalteromonas haloplanktis ANT/505


organism: Anguilla anguilla


organism: Salmonella enterica subsp. enterica serovar Typhimurium


organism: Arabidopsis thaliana


organism: Candida albicans


organism: Ascaris suum


organism: Pyrococcus furiosus


substrate_name: D-Tartrate


organism: Homo sapiens


organism: Astrosclera willeyana


organism: Campylobacter jejuni


organism: Bos taurus


substrate_name: COS


organism: Danio rerio


organism: Columba livia


organism: Cryptococcus neoformans


organism: Escherichia coli


organism: Flaveria bidentis


organism: Lacticaseibacillus rhamnosus


organism: Halomonas sp.


organism: Leishmania major

substrate_name: S-malate


organism: Oryza sativa


organism: Mesorhizobium loti


organism: Ovis aries


organism: Python bivittatus


organism: Rhizopus arrhizus


organism: Mus musculus


mutation_signature: truncated form of carbonic anhydrase VII lacking the amino-terminal 23 residues of recombinant enzyme truncated form of carbonic anhydrase VII lacking the amino


organism: Salmo trutta Labrax Coruhensis


organism: Saccharomyces cerevisiae


organism: Saccharolobus solfataricus


organism: Mytilus galloprovincialis


organism: Sordaria macrospora


organism: Schistosoma mansoni


organism: Trichomonas vaginalis


organism: Vibrio cholerae serotype O1


organism: Struthio camelus


organism: Trypanosoma cruzi


organism: Arabidopsis thaliana


enzyme_display_name: porphobilinogen synthase

organism: Ictalurus punctatus


organism: Zea mays

substrate_name: DL-isocitrate


organism: Bos taurus

substrate_name: cis-Aconitate; H2O


organism: Caenorhabditis elegans


organism: Synechocystis sp. PCC 6803 / Kazusa


mutation_signature: recombinant truncated CcaA220 enzyme / CO2 hydration reaction recombinant truncated CcaA220 enzyme


organism: Clostridium perfringens


organism: Cavia porcellus


organism: Dunaliella salina


organism: Cyprinus carpio


organism: Escherichia coli


organism: Felis catus


enzyme_display_name: tryptophan synthase

substrate_name: (3-Indolyl)-glycerol phosphate


substrate_name: Indole


organism: Helicobacter pylori


organism: Homo sapiens


substrate_name: 4-nitrophenyl phosphate


organism: Glycine max


organism: Lathyrus oleraceus


substrate_name: Unknown


organism: Mycobacterium tuberculosis


organism: Methanosarcina thermophila


organism: Mus musculus


organism: Oncorhynchus mykiss


organism: Nostoc sp.


organism: Oryctolagus cuniculus


organism: Persephonella marina


organism: Populus tremula


organism: Rattus norvegicus


organism: Rhodospirillum rubrum


organism: Saccharomyces cerevisiae


organism: Streptomyces lividans


organism: Sus scrofa


organism: Thalassiosira pseudonana


organism: Stylophora pistillata


organism: Thermovibrio ammonificans


organism: Trypanosoma brucei


organism: Thermus thermophilus

substrate_name: (S)-malate


organism: Escherichia coli

substrate_name: L-Malate


organism: Zea mays


organism: Arabidopsis thaliana

substrate_name: CO2; H2O


organism: Mycobacterium tuberculosis


organism: Penicillium chrysogenum


organism: Trypanosoma brucei brucei

substrate_name: Citrate


organism: Mycobacterium smegmatis


organism: Mycobacterium bovis

substrate_name: H2O; cis-Aconitate


organism: Plasmodium falciparum

substrate_name: cis-aconitate


enzyme_display_name: phenylserine aldolase

organism: Caulobacter vibrioides

substrate_name: L-threo-phenylserine


enzyme_display_name: 3-deoxy-D-manno-octulosonate aldolase

organism: Microbacterium barkeri


organism: Enterobacter cloacae


organism: Pseudomonas putida


enzyme_display_name: dimethylaniline-N-oxide aldolase

organism: Sus scrofa

substrate_name: N,N-dimethylnaphthylamine N-oxide


substrate_name: N,N-Dimethylaniline N-oxide


substrate_name: L-Thr


substrate_name: L-allo-Thr


substrate_name: N-acetyl-D-mannosamine


substrate_name: L-arabinose


enzyme_display_name: D-galactonate dehydratase

organism: Escherichia coli (strain K12)

substrate_name: D-galactonate


enzyme_display_name: mannonate dehydratase

organism: Thermoplasma acidophilum


substrate_name: D-mannonate


enzyme_display_name: UniProt A4VVI4

organism: Streptococcus suis


enzyme_display_name: UniProt P24215

organism: Escherichia coli


enzyme_display_name: dihydroneopterin aldolase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: 7,8-dihydroneopterin in the aldolase reaction


organism: Pneumocystis carinii

substrate_name: Unknown


substrate_name: 7,8-dihydroneopterin in aldolase reaction


organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)


enzyme_display_name: altronate dehydratase

organism: Paracidovorax avenae

substrate_name: D-idonate


substrate_name: L-fuconate


substrate_name: L-xylonate


organism: Mycobacterium tuberculosis


enzyme_display_name: galactonate dehydratase

organism: Aspergillus terreus


organism: Methanocaldococcus jannaschii


organism: Rhizobium leguminosarum bv. trifolii (strain WSM2304)

substrate_name: L-arabinonate


substrate_name: D-fuconate


organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)


organism: Caulobacter sp. (strain K31)


organism: Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15)


enzyme_display_name: dihydroxy-acid dehydratase


organism: Salmonella gallinarum (strain 287/91 / NCTC 13346)


organism: Sphingomonas sp. (strain SKA58)


organism: Streptomyces sp. (strain SPB78)


organism: Xanthomonas oryzae pv. oryzicola (strain BLS256)


organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)


organism: Escherichia coli (strain K12)

substrate_name: racemic 2,3-dihydroxy-3-methylbutanoate


organism: Cellvibrio japonicus (strain Ueda107)


organism: Chromohalobacter israelensis (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)


organism: Enterobacter sp. (strain 638)


organism: Escherichia albertii (strain TW07627)


organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)


organism: Escherichia coli (strain MS 21-1)


organism: Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9)


organism: Marinomonas sp. (strain MWYL1)


organism: Musicola paradisiaca (strain Ech703)


organism: Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)


organism: Pectobacterium carotovorum subsp. carotovorum (strain PC1)


organism: Rhizorhabdus wittichii (strain DSM 6014 / CCUG 31198 / JCM 15750 / NBRC 105917 / EY 4224 / RW1)


organism: Synechocystis sp. PCC 6803


organism: Pneumocystis carinii


enzyme_display_name: Cyanide hydratase

organism: Aspergillus niger

substrate_name: cyanide


substrate_name: fumaronitrile


organism: Fusarium solani


organism: Haemophilus influenzae


organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)

substrate_name: galactonate (at 60 degrees Celsius and pH 6.2)


substrate_name: gluconate (at 60 degrees Celsius and pH 6.2)


organism: Streptococcus suis


organism: Pseudomonas sp.


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: 7,8-dihydroneopterin (at 25 degrees Celsius)


organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)

substrate_name: L-threonate


substrate_name: D-galactonate


organism: Methanococcus aeolicus


organism: Mycobacterium butyricum


enzyme_display_name: D-fuconate dehydratase


substrate_name: L-arabonate


enzyme_display_name: trans-L-3-hydroxyproline dehydratase

organism: Rattus norvegicus


enzyme_display_name: UniProt Q67A25

organism: Thalictrum flavum


organism: Yarrowia lipolytica (strain CLIB 122 / E 150)


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

substrate_name: galactonate (at 70 degrees Celsius and pH 6)


organism: Arabidopsis thaliana


organism: Escherichia coli (strain K12)


organism: Escherichia coli


substrate_name: D-mannonate


organism: Saccharolobus solfataricus

substrate_name: D-gluconate


substrate_name: D-glycerate


organism: Spinacia oleracea


enzyme_display_name: nitrile hydratase

organism: Rhodococcus rhodochrous


substrate_name: cyanoacetamide


organism: Staphylococcus aureus


organism: Campylobacter jejuni


substrate_name: Unknown


organism: Neurospora crassa


substrate_name: Threonate


substrate_name: D-erythronate


organism: Klebsiella pneumoniae


substrate_name: D-fuconate


organism: Streptococcus suis


substrate_name: D-altronate


enzyme_display_name: UniProt Q4K977

organism: Pseudomonas fluorescens

substrate_name: 2-naphthyl isocyanide


enzyme_display_name: 2-hydroxyisoflavanone dehydratase

organism: Pueraria montana var. lobata


organism: Haemophilus influenzae


organism: Mycobacterium tuberculosis


organism: Cupriavidus necator


organism: Aspergillus fumigatus


enzyme_display_name: cyanase

organism: Thermomyces lanuginosus

substrate_name: Cyanate


enzyme_display_name: cyclohexyl-isocyanide hydratase

organism: Streptomyces thioluteus


substrate_name: cyclohexyl isocyanide


organism: Geobacter metallireducens


organism: Homo sapiens

substrate_name: S-methyl-5-thio-D-ribulose 1-phosphate


enzyme_display_name: aldos-2-ulose dehydratase

organism: Phanerodontia chrysosporium


organism: Syntrophus aciditrophicus


enzyme_display_name: 16alpha-hydroxyprogesterone dehydratase

organism: Eubacterium sp.


enzyme_display_name: 2-methylisocitrate dehydratase

organism: Yarrowia lipolytica


organism: Pseudonocardia thermophila

substrate_name: Benzonitrile


substrate_name: acrylonitrile


substrate_name: Methacrylonitrile


organism: Glycine max


organism: Arthrobacter pascens


enzyme_display_name: bile-acid 7alpha-dehydratase


organism: [Clostridium] scindens


enzyme_display_name: o-succinylbenzoate synthase

organism: Geobacillus kaustophilus

substrate_name: N-succinyl-L-alanine


substrate_name: N-succinyl-L-phenylalanine


substrate_name: N-acetyl-L-methionine


substrate_name: N-acetyl-L-phenylalanine


substrate_name: N-carbamoyl-L-methionine


organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)

substrate_name: cis-aconitate (at pH 8)


substrate_name: citrate (at pH 8)


substrate_name: isocitrate (at pH 8)


organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)

substrate_name: N-succinyl-L-phenylglycine


substrate_name: SHCHC


organism: Enterococcus faecalis (strain ATCC 700802 / V583)


organism: [Clostridium] hylemonae


organism: Peptacetobacter hiranonis


enzyme_display_name: 3-hydroxypropionyl-CoA dehydratase

organism: Nitrosopumilus maritimus

substrate_name: (E)-octenoyl-CoA


substrate_name: crotonyl-CoA


substrate_name: acryloyl-CoA


substrate_name: methacrylyl-CoA


enzyme_display_name: tryptophan synthase (indole-salvaging)

organism: Thermotoga maritima

substrate_name: O-Phospho-L-serine


enzyme_display_name: enoyl-CoA hydratase 2

organism: Cucumis sativus


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Gluconobacter oxydans


enzyme_display_name: 4-hydroxybutanoyl-CoA dehydratase

organism: Metallosphaera sedula


substrate_name: L-serine


substrate_name: indole


organism: Penicillium parvum


organism: Thermococcus kodakarensis


organism: Geobacillus kaustophilus (strain HTA426)

substrate_name: N-succinyl-L-valine


substrate_name: N-succinyl-L-alanine


substrate_name: N-succinyl-L-methionine


substrate_name: N-succinyl-L-tyrosine


substrate_name: N-succinyl-L-serine


substrate_name: N-succinyl-L-isoleucine


substrate_name: N-succinyl-L-phenylalanine


substrate_name: N-succinyl-L-leucine


enzyme_display_name: D-lactate dehydratase

organism: Homo sapiens

substrate_name: methylglyoxal


enzyme_display_name: short-chain-enoyl-CoA hydratase

organism: Meiothermus ruber


organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: L-threonine


organism: Zea mays


organism: Syntrophothermus lipocalidus


substrate_name: (E)-octenoyl-CoA


enzyme_display_name: UniProt O52793

organism: Amycolatopsis orientalis


organism: Arabidopsis thaliana


substrate_name: Indole; O-Phospho-L-serine


enzyme_display_name: pterocarpan synthase

organism: Lathyrus oleraceus


organism: Medicago sativa


enzyme_display_name: (R)-2-hydroxyisocaproyl-CoA dehydratase

organism: Clostridium difficile


substrate_name: Phenylglyoxal


enzyme_display_name: squalene--hopanol cyclase

organism: Tetrahymena thermophila

substrate_name: squalene


organism: Nitrosopumilus maritimus


substrate_name: crotonyl-CoA


enzyme_display_name: gluconate/galactonate dehydratase

organism: Picrophilus oshimae

substrate_name: D-galactonate


organism: Metallosphaera sedula


organism: Alicyclobacillus acidocaldarius


enzyme_display_name: L-talarate dehydratase

substrate_name: L-talarate


enzyme_display_name: L-lyxonate dehydratase

organism: Roseibium aggregatum

substrate_name: L-lyxonate


substrate_name: D-gulonate


enzyme_display_name: (R)-2-hydroxyglutaryl-CoA dehydratase

organism: [Clostridium] symbiosum


enzyme_display_name: linalool dehydratase

organism: Castellaniella defragrans


substrate_name: myrcene


enzyme_display_name: tetracenomycin F2 cyclase

organism: Streptomyces glaucescens

substrate_name: tetracenomycin F2


enzyme_display_name: cis-L-3-hydroxyproline dehydratase

organism: Azospirillum brasilense


organism: Micromonospora viridifaciens


organism: Aeromonas caviae

substrate_name: hexenoyl-CoA


enzyme_display_name: colneleate synthase

organism: Allium sativum


organism: Caenorhabditis elegans


substrate_name: glyoxal


organism: Homo sapiens

substrate_name: all-trans-retinol


substrate_name: all-trans-retinal


substrate_name: arachidonic acid


enzyme_display_name: 2-hydroxyisoflavanone dehydratase

organism: Glycyrrhiza echinata


organism: Escherichia coli (strain K12)

substrate_name: Lys-AMC (at 37 degrees Celsius and pH 8.5)


substrate_name: Arg-AMC (at 37 degrees Celsius and pH 8.5)


substrate_name: Ala-AMC (at 37 degrees Celsius and pH 8.5)


enzyme_display_name: o-succinylbenzoate synthase

organism: Geobacillus stearothermophilus

substrate_name: N-formyl-D-methionine


substrate_name: N-formyl-D-norleucine


enzyme_display_name: pectate lyase

organism: Streptomyces nitrosporeus

substrate_name: tetragalacturonic acid


substrate_name: trigalacturonic acid


enzyme_display_name: UniProt P39116

organism: Bacillus subtilis

substrate_name: trigalacturonate


enzyme_display_name: trans-4-hydroxy-L-proline dehydratase

organism: Clostridioides difficile


organism: Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)

substrate_name: SHCHC


substrate_name: N-succinyl-L-phenylglycine


organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)


enzyme_display_name: difructose-anhydride-I synthase

organism: Aspergillus fumigatus

substrate_name: bis-D-fructose 2',1:2,1' dianhydride


substrate_name: bis-D-fructose 2',1:2,1'-dianhydride


substrate_name: Inulobiose


enzyme_display_name: D-lactate dehydratase

organism: Schizosaccharomyces pombe

substrate_name: methylglyoxal


organism: Solanum lycopersicum


enzyme_display_name: difructose-dianhydride-III synthase

organism: Paenarthrobacter ureafaciens


enzyme_display_name: etheroleic acid synthase

organism: Asparagus officinalis


organism: Pseudarthrobacter chlorophenolicus


organism: uncultured bacterium

substrate_name: Pectin


substrate_name: polygalacturonic acid


organism: Paenarthrobacter aurescens

substrate_name: di-D-fructofuranose 1,2:2,3 dianhydride


organism: Actinomadura keratinilytica

substrate_name: Polygalacturonate


organism: Arthrobacter sp. H65-7


organism: Thermobifida fusca

substrate_name: Unknown


organism: Thermotoga maritima


enzyme_display_name: pterocarpan synthase

organism: Glycyrrhiza echinata


organism: Mus musculus

substrate_name: all-trans-retinol


substrate_name: all-trans-retinal


substrate_name: arachidonic acid


enzyme_display_name: methanogen homoaconitase

organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: cis-homoaconitate


substrate_name: maleate


substrate_name: (R)-homocitrate


organism: Homo sapiens


substrate_name: 17-beta-estradiol (2-hydroxylation)


substrate_name: progesterone (6-beta-hydroxylation)


organism: Amycolatopsis orientalis


enzyme_display_name: methylthioacryloyl-CoA hydratase

organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)

substrate_name: 3-(methylthio)acryloyl-CoA (for CoA ester hydrolysis)


substrate_name: 3-(methylthio)propanoyl-CoA (for CoA ester hydrolysis)


substrate_name: 3-hydroxybutyryl-CoA (for CoA ester hydrolysis)


substrate_name: crotonyl-CoA (for hydration)


enzyme_display_name: (R)-3-(aryl)lactoyl-CoA dehydratase

organism: Clostridium sporogenes

substrate_name: (E)-cinnamoyl-CoA (at pH 8 and 20 degrees Celsius)


substrate_name: cinnamoyl-CoA (at pH 8 and 20 degrees Celsius)


substrate_name: cis-aconitate


organism: Amycolatopsis sp.


enzyme_display_name: ectoine synthase

organism: Sphingopyxis alaskensis


organism: Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)

substrate_name: SHCHC


organism: Amycolatopsis sp

substrate_name: N-acetyl-L-methionine


organism: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)

substrate_name: N-acetyl-D-methionine


organism: Echinicola rosea

substrate_name: Polygalacturonate


organism: Bifidobacterium dentium

substrate_name: 4-nitrophenyl alpha-D-arabinofuranoside


substrate_name: difructose dianhydride I


substrate_name: Inulobiose


substrate_name: (R)-homocitrate (at 60 degrees Celsius)


organism: Selaginella moellendorffii


enzyme_display_name: enoyl-CoA hydratase 2

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: dodecenoyl-CoA


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)


enzyme_display_name: cyanase

organism: Sordaria macrospora

substrate_name: Cyanate


enzyme_display_name: linalool dehydratase

organism: Castellaniella defragrans

substrate_name: linalool


enzyme_display_name: phosphomevalonate dehydratase

organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: tAHMP


enzyme_display_name: squalene--hopanol cyclase

organism: Alicyclobacillus acidocaldarius

substrate_name: squalene


enzyme_display_name: heparin lyase

organism: Pedobacter heparinus

substrate_name: heparin


enzyme_display_name: pectate disaccharide-lyase

organism: Pectobacterium carotovorum

substrate_name: trigalacturonate


organism: Escherichia coli (strain K12)

substrate_name: methylglyoxal


organism: Bacillus subtilis (strain 168)

substrate_name: ADP


organism: Ranunculus acris


enzyme_display_name: mannuronate-specific alginate lyase

organism: Bacteroides cellulosilyticus

substrate_name: alginate


substrate_name: poly(beta-(1->4)-D-mannuronic acid)


organism: Bacillus weihaiensis


organism: Flammeovirga sp. NJ-04


organism: Saccharophagus degradans

substrate_name: sodium alginate


enzyme_display_name: pectin lyase

organism: Curvularia inaequalis

substrate_name: Pectin


organism: Wenyingzhuangia fucanilytica


organism: Persicobacter sp. CCB-QB2

mutation_signature: truncated protein lacking both the CBM16 and CBM32 domains


mutation_signature: truncated protein lacking the CBM16 domain


organism: Isoptericola halotolerans

substrate_name: poly(alpha-(1,4)-L-guluronic acid)


enzyme_display_name: guluronate-specific alginate lyase


enzyme_display_name: exo-(1->4)-alpha-D-glucan lyase

organism: Gracilariopsis chorda

substrate_name: glycogen


substrate_name: amylopectin


substrate_name: maltotetraose


substrate_name: maltopentaose


substrate_name: maltohexaose


substrate_name: maltoheptaose


substrate_name: maltotriose


substrate_name: maltose


enzyme_display_name: oligogalacturonide lyase

organism: Erwinia aroidea

substrate_name: unsaturated digalacturonic acid


substrate_name: digalacturonic acid


organism: Vibrio xiamenensis


mutation_signature: truncated enzyme TM1


mutation_signature: truncated enzyme TM2


enzyme_display_name: glucuronan lyase

organism: Trichoderma harzianum

substrate_name: deacetylated glucuronan


organism: Flavobacterium sp.


organism: Fusarium lateritium

substrate_name: citrus pectin


organism: Marinimicrobium sp. H1


organism: Pseudomonas aeruginosa

substrate_name: acetylated alginate


substrate_name: alginate


organism: Microbulbifer sp. BY17

substrate_name: poly(beta-(1->4)-D-mannuronic acid)


organism: Microbulbifer sp. ALW1


organism: Vibrio splendidus


organism: Zobellia galactanivorans

substrate_name: sodium alginate


organism: Paenarthrobacter ureafaciens

substrate_name: inulin


organism: Trichoderma parareesei

substrate_name: glucuronan


organism: Rubrivirga marina

substrate_name: poly(alpha-(1->4)-L-guluronic acid)


organism: Leifsonia sp. T88-4


organism: Microbacterium sp. S48-1


organism: Saccharophagus degradans


organism: Thalassotalea algicola


organism: Littorina sp.


organism: Pseudarthrobacter chlorophenolicus


enzyme_display_name: chondroitin AC lyase

organism: Paenarthrobacter aurescens

substrate_name: chondroitin 4-sulfate


organism: Niallia circulans

substrate_name: heparan sulfate


enzyme_display_name: pectate lyase

organism: Penicillium occitanis (nom. inval.)

substrate_name: polygalacturonic acid


enzyme_display_name: o-succinylbenzoate synthase

organism: Amycolatopsis sp


enzyme_display_name: etheroleic acid synthase

organism: Allium sativum


organism: Pseudopedobacter saltans

substrate_name: heparin


organism: Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)

substrate_name: tAHMP


organism: Exiguobacterium sp.


organism: Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)

substrate_name: SHCHC


organism: Staphylococcus aureus (strain COL)


enzyme_display_name: 3-hydroxypropionyl-CoA dehydratase

organism: Metallosphaera sedula


organism: Desulfotalea psychrophila (strain LSv54 / DSM 12343)


enzyme_display_name: N-acetylmuramic acid 6-phosphate etherase

organism: Escherichia coli (strain K12)

substrate_name: N-acetylmuramic acid 6-phosphate


enzyme_display_name: enoyl-CoA hydratase 2

organism: Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)

substrate_name: crotonyl-CoA


organism: Vibrio splendidus


substrate_name: N-succinyl-L-phenylglycine


organism: Aspergillus flavus


enzyme_display_name: linalool dehydratase

organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen)

substrate_name: beta-myrcene


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


enzyme_display_name: D-lactate dehydratase

organism: Escherichia coli

substrate_name: methylglyoxal


substrate_name: alginate


organism: Candida albicans (strain SC5314 / ATCC MYA-2876)


substrate_name: geraniol


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


enzyme_display_name: xanthan lyase

organism: Bacillus sp. GL1

substrate_name: Xanthan


enzyme_display_name: (+)-caryolan-1-ol synthase

organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235)

substrate_name: farnesyl diphosphate (at pH 7.5 and 30 degrees Celsius)


enzyme_display_name: mannuronate-specific alginate lyase

organism: Defluviitalea phaphyphila


enzyme_display_name: 3-amino-5-hydroxybenzoate synthase

organism: Amycolatopsis mediterranei


enzyme_display_name: 2-methylfumaryl-CoA hydratase

organism: Chloroflexus aurantiacus


organism: Methylorubrum extorquens

substrate_name: formaldehyde


enzyme_display_name: gluconate/galactonate dehydratase

organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

substrate_name: galactonate (at 70 degrees Celsius and pH 6)


organism: Pseudomonas aeruginosa

substrate_name: UDP-N-acetylglucosamine

mutation_signature: recombinant soluble truncated WbpM mutant His-S262


organism: Cereibacter sphaeroides


enzyme_display_name: 3-methylfumaryl-CoA hydratase

organism: Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)

substrate_name: 3-methylfumaryl-CoA (at 45 degrees Celsius)


enzyme_display_name: L-talarate dehydratase

organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: L-talarate


enzyme_display_name: chorismate dehydratase

organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

substrate_name: chorismate


organism: Oceanobacillus iheyensis

substrate_name: galactarate


organism: Saccharopolyspora spinosa


organism: Saccharolobus solfataricus

substrate_name: D-galactonate


organism: Bacillus sp. (in: firmicutes)

substrate_name: inulin


enzyme_display_name: (2S)-3-sulfopropanediol dehydratase

organism: Klebsiella oxytoca


enzyme_display_name: guluronate-specific alginate lyase

organism: Persicobacter sp. CCB-QB2


enzyme_display_name: pectin lyase

organism: Aspergillus terricola

substrate_name: Pectin


enzyme_display_name: trans-4-hydroxy-L-proline dehydratase

organism: Clostridioides difficile


organism: Streptomyces peucetius subsp. caesius


organism: Bacillus sp. (strain GL1)

substrate_name: xanthan


organism: Yersinia pseudotuberculosis

substrate_name: GDP-4-keto-6-deoxy-D-mannose (at pH 7 and 37 degrees Celsius)


substrate_name: L-glutamate (at pH 7 and 37 degrees Celsius)


enzyme_display_name: galactonate dehydratase

organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

substrate_name: gluconate


substrate_name: alginate


organism: Vibrio sp. NJ-04


organism: Zobellia galactanivorans

substrate_name: sodium alginate


enzyme_display_name: crotonobetainyl-CoA hydratase

organism: Escherichia coli

substrate_name: H2O; Crotonobetainyl-CoA


organism: Proteus sp. (in: enterobacteria)


enzyme_display_name: short-chain-enoyl-CoA hydratase

organism: Clostridium acetobutylicum

substrate_name: H2O; Crotonoyl-CoA


organism: Homo sapiens


enzyme_display_name: (R)-2-hydroxyisocaproyl-CoA dehydratase


enzyme_display_name: pectate lyase

organism: Massilia eurypsychrophila

substrate_name: polygalacturonic acid


organism: Streptomyces nitrosporeus

substrate_name: pentagalacturonic acid


organism: Microbulbifer sp. 6532A

substrate_name: poly(alpha-(1->4)-L-guluronic acid)


organism: Paenibacillus sp. FPU-7


organism: Vibrio sp. Ni1


enzyme_display_name: heparin lyase

organism: Pedobacter heparinus

substrate_name: H2O; m n n+m m n n+m n m n+m n m n+m m n n+m m n n+m m n n+m m n n+m n m n+m m n n+m m n n+m m n n+m n m n+m m n n+m Heparin


organism: Aspergillus terricola

substrate_name: citrus pectin


organism: Isoptericola halotolerans


organism: Saccharophagus degradans


enzyme_display_name: anhydrosialidase

organism: Macrobdella decora


organism: Streptomyces davaonensis


organism: Bacillus subtilis

substrate_name: tetragalacturonate


organism: Sphingobacterium sp.

substrate_name: N-acetyl-de-O-sulfated heparin


enzyme_display_name: heparin-sulfate lyase

organism: Bacteroides stercoris

substrate_name: Heparin


organism: Bacteroides thetaiotaomicron

substrate_name: Heparan sulfate


organism: Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)

substrate_name: ulvan


enzyme_display_name: pectate disaccharide-lyase

organism: Pectobacterium carotovorum

substrate_name: polygalacturonate I


enzyme_display_name: cis-L-3-hydroxyproline dehydratase

organism: Agrobacterium tumefaciens


enzyme_display_name: cyclohexyl-isocyanide hydratase

organism: Pseudomonas putida

substrate_name: Unknown


enzyme_display_name: cyanase

organism: Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)


enzyme_display_name: ectoine synthase

organism: Halomonas elongata

substrate_name: L-homoectoine


organism: Sphingopyxis alaskensis


organism: Bacillus subtilis (strain 168)


organism: Homo sapiens


enzyme_display_name: bile-acid 7alpha-dehydratase

organism: Clostridium scindens (strain JCM 10418 / VPI 12708)


substrate_name: trans-Dec-2-enoyl-CoA; H2O


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Bacillus anthracis


organism: Neurospora crassa


enzyme_display_name: enoyl-CoA hydratase 2

organism: Aeromonas caviae

substrate_name: Crotonoyl-CoA; H2O


substrate_name: H2O; trans-Hex-2-enoyl-CoA


organism: Clostridioides difficile


organism: Amycolatopsis orientalis

substrate_name: dTDP-glucose


enzyme_display_name: hyaluronate lyase

organism: Streptococcus pneumoniae

substrate_name: Hyaluronate


organism: Streptococcus pyogenes

substrate_name: H2O; Hyaluronate


organism: Streptococcus pyogenes phage


organism: Thermasporomyces composti

substrate_name: hyaluronate


enzyme_display_name: tryptophan synthase (indole-salvaging)

organism: Thermotoga maritima

substrate_name: Indole; O-Phospho-L-serine


enzyme_display_name: tetrahymanol synthase

organism: Tetrahymena thermophila (strain SB210)

substrate_name: sqna!ene


enzyme_display_name: carotenoid 1,2-hydratase

organism: Rhodobacter capsulatus

substrate_name: H2O; Neurosporene


organism: Rubrivivax gelatinosus

substrate_name: Neurosporene; H2O


organism: Escherichia coli (strain K12)

substrate_name: (S)-NADHX


organism: Methylobacterium extorquens


organism: Pseudomonas aeruginosa


organism: Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1)


organism: Drosophila melanogaster


enzyme_display_name: mannuronate-specific alginate lyase

organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

substrate_name: alginate (dp value of 263)


organism: Hypocrea jecorina (strain QM6a)

substrate_name: cis-3-hydroxy-L-proline (at pH 8.0)


organism: Stenotrophomonas maltophilia

substrate_name: alginate


enzyme_display_name: acetylene hydratase

organism: Syntrophotalea acetylenica

substrate_name: Unknown


enzyme_display_name: o-succinylbenzoate synthase

organism: Amycolatopsis sp

substrate_name: N-succinyl-R-methionine


organism: Bacillus subtilis (strain 168)


organism: Geobacillus kaustophilus

substrate_name: N-succinyl-D-alanine


organism: Geobacillus stearothermophilus

substrate_name: N-formyl-D-aminobutyric acid


organism: Rhodospirillum rubrum

substrate_name: Crotonoyl-CoA; H2O


enzyme_display_name: colneleate synthase

organism: Solanum tuberosum


enzyme_display_name: linalool dehydratase

organism: Castellaniella defragrans (strain DSM 12143 / CCUG 39792 / 65Phen)


organism: Thiocapsa roseopersicina


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


substrate_name: NADHX


organism: Escherichia coli


enzyme_display_name: pterocarpan synthase

organism: Glycyrrhiza echinata


enzyme_display_name: gluconate/galactonate dehydratase

organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)


organism: Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)


enzyme_display_name: 5'-oxoaverantin cyclase

organism: Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1)


enzyme_display_name: versicolorin B synthase

organism: Aspergillus parasiticus


organism: Methanosarcina barkeri (strain Fusaro / DSM 804)


enzyme_display_name: 2-methylfumaryl-CoA hydratase

organism: Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)


organism: Danio rerio


organism: Homo sapiens


enzyme_display_name: methanogen homoaconitase

organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

substrate_name: cis-homo(2)-aconitate (at 60 degrees Celsius)


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Pseudomonas putida


enzyme_display_name: enoyl-CoA hydratase 2

organism: Aeromonas caviae


substrate_name: synthetic fatty acid 9E,11Z,14Z-20:3omega6 (at pH 7.5)


organism: Sus scrofa


enzyme_display_name: tetracenomycin F2 cyclase

organism: Streptomyces glaucescens


enzyme_display_name: cis-L-3-hydroxyproline dehydratase

organism: Agrobacterium fabrum (strain C58 / ATCC 33970)


organism: Hypocrea jecorina (strain QM6a)


enzyme_display_name: pectate lyase

organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)


organism: Paenibacillus barcinonensis


organism: Zinnia elegans


organism: Defluviitalea phaphyphila

substrate_name: poly(beta-(1->4)-D-mannuronic acid)


organism: Pseudoalteromonas sp. SM0524

substrate_name: sodium alginate


enzyme_display_name: hyaluronate lyase

organism: Streptococcus pyogenes phage H4489A

substrate_name: hyaluronic acid


enzyme_display_name: pectin lyase

organism: Bacillus subtilis (strain 168)


enzyme_display_name: guluronate-specific alginate lyase

organism: Corynebacterium sp.

substrate_name: saturated deca((1-4)-alpha-L-guluronan)


enzyme_display_name: xanthan lyase

organism: Bacillus sp. GL1


organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)


enzyme_display_name: (E)-benzylidenesuccinyl-CoA hydratase

organism: Thauera aromatica


enzyme_display_name: 2-methylisocitrate dehydratase

organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)


organism: Escherichia coli (strain K12)


organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)


organism: Stenotrophomonas maltophilia (strain K279a)

substrate_name: poly-GlcA


enzyme_display_name: mannuronate-specific alginate lyase

substrate_name: mannuronan (dp value of 133)


organism: Stenotrophomonas maltophilia


enzyme_display_name: chondroitin AC lyase

organism: Pedobacter heparinus


substrate_name: chondroitin 6-sulfate


enzyme_display_name: glucuronan lyase


organism: Paenarthrobacter aurescens

substrate_name: inulin


organism: Aspergillus luchuensis var. saitoi

substrate_name: Polygalacturonate


organism: Bacillus sp. (in: firmicutes)

substrate_name: polygalacturonic acid


organism: Bacillus sp. N16-5


organism: Bacillus subtilis


substrate_name: Unknown


enzyme_display_name: heparin-sulfate lyase

substrate_name: heparan sulfate


substrate_name: hyaluronate


organism: Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)


enzyme_display_name: rhamnogalacturonan endolyase

organism: Acetivibrio thermocellus

substrate_name: potato galactan

mutation_signature: truncated mutant


substrate_name: Pectin


organism: Ruminiclostridium cellulolyticum

substrate_name: potato pectic galactan


enzyme_display_name: oligo-alginate lyase

organism: Zobellia galactanivorans


enzyme_display_name: o-succinylbenzoate synthase

organism: Thermobifida fusca


enzyme_display_name: chondroitin-sulfate-ABC exolyase

organism: Vibrio hyugaensis

substrate_name: chondroitin sulfate C


substrate_name: chondroitin sulfate B


organism: Proteus vulgaris

substrate_name: dermatan sulfate


enzyme_display_name: chondroitin B lyase

substrate_name: Dermatan sulfate


organism: Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)

substrate_name: alginate (at pH 6 and 40 degrees Celsius)


substrate_name: alginate


enzyme_display_name: chondroitin-sulfate-ABC endolyase

substrate_name: chondroitin 4-sulfate


organism: Bacteroides thetaiotaomicron

substrate_name: Chondroitin 4-sulfate


substrate_name: chondroitin 6-sulfate


organism: Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1)

substrate_name: ulvan


enzyme_display_name: pectate trisaccharide-lyase

organism: Thermotoga maritima

substrate_name: polygalacturonic acid


organism: Bacillus subtilis (strain 168)

substrate_name: rhamnogalacturonan (RG) type I region of plant cell wall pectin


enzyme_display_name: rhamnogalacturonan exolyase


organism: Stenotrophomonas maltophilia


enzyme_display_name: gellan lyase

organism: Geobacillus stearothermophilus

substrate_name: gellan


substrate_name: low viscosity alginate (at pH 7.5 and 30 degrees Celsius)


organism: Escherichia coli


enzyme_display_name: heparin lyase

organism: Pedobacter heparinus

substrate_name: Heparin


enzyme_display_name: UniProt Q5SL02

organism: Thermus thermophilus

substrate_name: O-phospho-L-homoserine


substrate_name: L-Vinylglycine


substrate_name: phosphate


enzyme_display_name: 3-hydroxypropionyl-CoA dehydratase

organism: Metallosphaera sedula


substrate_name: acryloyl-CoA


substrate_name: (E)-octenoyl-CoA


substrate_name: crotonyl-CoA


substrate_name: methacrylyl-CoA


enzyme_display_name: tetracenomycin F2 cyclase

organism: Streptomyces glaucescens

substrate_name: tetracenomycin F2


substrate_name: Dermatan sulfate


substrate_name: Chondroitin 4-sulfate


organism: Fusarium oxysporum

substrate_name: Gum arabic


enzyme_display_name: threonine synthase

organism: Lemna aequinoctialis


enzyme_display_name: ethanolamine-phosphate phospho-lyase

organism: Achromobacter sp.

substrate_name: Ethanolamine phosphate


organism: Homo sapiens


substrate_name: phenacetin


organism: Flavobacterium rhenanum


organism: Microbacterium arborescens


enzyme_display_name: methylglyoxal synthase

organism: Saccharomyces cerevisiae

substrate_name: dihydroxyacetone phosphate


enzyme_display_name: chorismate synthase

organism: Euglena gracilis

substrate_name: 5-enolpyruvylshikimate 3-phosphate


organism: Beta vulgaris

substrate_name: O-Phospho-L-homoserine; H2O


substrate_name: O-phosphohomoserine


enzyme_display_name: 2-methylfumaryl-CoA hydratase

organism: Haloarcula hispanica


substrate_name: (S)-malyl-CoA


organism: Solanum lycopersicum


enzyme_display_name: 3-dehydroquinate synthase

organism: Providencia alcalifaciens


organism: Proteus vulgaris

substrate_name: dermatan sulfate


organism: Pedobacter heparinus


organism: Thermus sp.


organism: Oryctolagus cuniculus

substrate_name: dihydroxyacetone phosphate (at pH 7.9)


organism: Escherichia coli

substrate_name: Glycerone phosphate


organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

substrate_name: NADPH


organism: Arabidopsis thaliana


substrate_name: H2O; Ethanolamine phosphate


organism: Actinidia chinensis


organism: Pyrococcus furiosus


organism: Aspergillus nidulans

substrate_name: NAD+


organism: Neurospora crassa


organism: Homo sapiens

substrate_name: Unknown


organism: Escherichia coli (strain K12)


organism: Thermus sp. GH5

substrate_name: glycerone phosphate


substrate_name: EPSP


organism: Capnoides sempervirens


enzyme_display_name: guluronate-specific alginate lyase

organism: Saccharophagus degradans

substrate_name: sodium alginate


enzyme_display_name: enoyl-CoA hydratase 2

organism: Aeromonas caviae


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Bacillus anthracis


enzyme_display_name: chondroitin-sulfate-ABC endolyase

organism: Proteus vulgaris

substrate_name: chondroitin 4-sulfate


enzyme_display_name: oligo-alginate lyase

organism: Stenotrophomonas maltophilia

substrate_name: (Alginate)n


substrate_name: alginate


enzyme_display_name: Casbene synthase, chloroplastic

organism: Ricinus communis

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: UniProt P27213

organism: Rattus norvegicus


enzyme_display_name: UniProt Q39761

organism: Gossypium arboreum

substrate_name: (2E,6E)-farnesyl diphosphate


substrate_name: (2E,6Z)-farnesyl diphosphate


substrate_name: nerolidyl diphosphate


organism: Metallosphaera sedula


enzyme_display_name: sabinene-hydrate synthase

organism: Origanum majorana

substrate_name: (3S)-linalyl diphosphate


substrate_name: geranyl diphosphate


substrate_name: 6,7-dihydrogeranyl diphosphate


enzyme_display_name: L-lyxonate dehydratase

organism: Roseibium aggregatum

substrate_name: D-gulonate


substrate_name: L-lyxonate


enzyme_display_name: (-)-endo-fenchol synthase

organism: Anethum foeniculum


substrate_name: 2,3-cyclopropylgeranyl diphosphate


enzyme_display_name: colneleate synthase

organism: Solanum tuberosum


enzyme_display_name: chondroitin-sulfate-ABC exolyase

organism: Bacteroides thetaiotaomicron

substrate_name: Chondroitin 4-sulfate


substrate_name: Dermatan sulfate


enzyme_display_name: aristolochene synthase

organism: Escherichia coli

substrate_name: farnesyl diphosphate


substrate_name: Unknown


enzyme_display_name: 2-methylisocitrate dehydratase

organism: Escherichia coli (strain K12)

substrate_name: citrate


substrate_name: cis-aconitate


substrate_name: isocitrate (using 0.01-0.8 mM substrate)


enzyme_display_name: (+)-delta-cadinene synthase

organism: Phyla dulcis


organism: Nicotiana tabacum


substrate_name: anilinogeranyl diphosphate


substrate_name: (2E,6E)-farnesyl diphosphate


enzyme_display_name: 6-pyruvoyltetrahydropterin synthase

substrate_name: sepiapterin


enzyme_display_name: pentalenene synthase

organism: Streptomyces exfoliatus


organism: Penicillium roqueforti


substrate_name: trans,trans-Farnesyl diphosphate


substrate_name: trans,trans-farnesyl diphosphate


enzyme_display_name: chorismate synthase

organism: Neurospora crassa

substrate_name: NADPH


organism: Mus musculus

substrate_name: dihydroneopterin triphosphate


enzyme_display_name: casbene synthase

organism: Ricinus communis

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: threonine synthase

substrate_name: L-Serine


substrate_name: O-Phospho-L-homoserine


organism: Homo sapiens


organism: Aspergillus terreus


organism: Gossypium arboreum


substrate_name: 7,8-Dihydroneopterin 3'-triphosphate


enzyme_display_name: 3-dehydroquinate synthase


enzyme_display_name: ectoine synthase

organism: Sphingopyxis alaskensis


enzyme_display_name: (-)-limonene synthase TPS1, chloroplastic

organism: Cannabis sativa

substrate_name: Geranyl pyrophosphate


enzyme_display_name: (+)-alpha-pinene synthase TPS2, chloroplastic


enzyme_display_name: Ent-kaur-16-ene synthase, chloroplastic

organism: Cucurbita maxima

substrate_name: copalyl diphosphate


substrate_name: farnesyl diphosphate


enzyme_display_name: carotenoid 1,2-hydratase

organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)

substrate_name: lycopene (at pH 8 and at 28 degrees Celsius)


substrate_name: neurosporene (at pH 8 and at 28 degrees Celsius)


organism: Helicobacter pylori

substrate_name: UDP-N-acetyl-D-glucosamine


enzyme_display_name: ent-kaurene synthase

organism: Marah macrocarpa


enzyme_display_name: (4S)-limonene synthase

organism: Mentha sp.

substrate_name: Unknown


organism: Ricciocarpos natans

substrate_name: geranyl diphosphate


substrate_name: neryl diphosphate


substrate_name: (3R)-linalyl diphosphate


enzyme_display_name: abieta-7,13-diene synthase

organism: Abies grandis


organism: Fusarium verticillioides


enzyme_display_name: myrcene synthase

organism: Salvia fruticosa

substrate_name: (2E)-geranyl diphosphate


enzyme_display_name: taxadiene synthase

organism: Taxus canadensis


organism: Hedychium coronarium


organism: Arabidopsis thaliana

substrate_name: ent-copalyl diphosphate


enzyme_display_name: (R)-limonene synthase

organism: Citrus sinensis

substrate_name: Geranyl diphosphate


organism: Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)


organism: Taxus brevifolia

substrate_name: Geranylgeranyl diphosphate


substrate_name: 2-Fluoroneryl diphosphate


organism: Lavandula angustifolia

mutation_signature: truncated protein LaLIMS_RR / truncated protein


enzyme_display_name: germacrene-A synthase

organism: Ixeridium dentatum

substrate_name: 2-trans,6-trans-farnesyl diphosphate


enzyme_display_name: S-linalool synthase

organism: Actinidia arguta


organism: Zea mays


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


enzyme_display_name: germacradienol synthase

organism: Streptomyces avermitilis


organism: Cereus peruvianus


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


organism: Mentha spicata

substrate_name: 3S-Linalyl diphosphate


enzyme_display_name: amorpha-4,11-diene synthase

organism: Penicillium roqueforti


organism: Camellia sinensis var. sinensis


enzyme_display_name: R-linalool synthase


organism: Cyclocybe aegerita


enzyme_display_name: isoprene synthase

organism: Bauhinia variegata

substrate_name: dimethylallyl diphosphate


organism: Nostoc sp.


enzyme_display_name: (+)-delta-cadinene synthase

organism: Piper nigrum

substrate_name: (2E,6E)-farnesyl diphosphate


organism: Actinidia polygama


organism: Artemisia annua


organism: Solidago canadensis


organism: Citrus x limon


organism: Coleus amboinicus


organism: Agrocybe pediades


organism: Santalum album


organism: Barnadesia spinosa


organism: Ixeridium dentatum


organism: Robinia pseudoacacia


organism: Calophyllum inophyllum


organism: Campylopus introflexus


organism: Ipomoea batatas


organism: Salix discolor


organism: Metrosideros polymorpha


organism: Syzygium cumini


organism: Syzygium samarangense


organism: Mangifera indica


organism: Garcinia subelliptica


organism: Artemisia annua


organism: Nicotiana suaveolens


organism: Clarkia breweri


organism: Citrus sinensis

substrate_name: 2-Fluorogeranyl diphosphate


organism: Hedychium coronarium


enzyme_display_name: ent-sandaracopimaradiene synthase

organism: Oryza sativa


organism: Cichorium intybus


organism: Zea mays


substrate_name: farnesyl diphosphate


substrate_name: magnesium


substrate_name: manganese


substrate_name: geranyl diphosphate


organism: Streptomyces coelicolor

substrate_name: trans,trans-Farnesyl diphosphate; H2O


substrate_name: manganese ions


substrate_name: H2O; Geranyl diphosphate


organism: Escherichia coli (strain K12)

substrate_name: (S)-NADPHX


substrate_name: ADP


organism: Arabidopsis thaliana


substrate_name: farnesyl diphosphate (at pH 7.5)


substrate_name: geranylgeranyl diphosphate (at pH 7.5)


substrate_name: geranyl diphosphate (at pH 7.5)


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


enzyme_display_name: epi-isozizaene synthase

organism: Streptomyces avermitilis


enzyme_display_name: gluconate/galactonate dehydratase

organism: Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3)

substrate_name: galactonate (at 60 degrees Celsius and pH 6.2)


substrate_name: gluconate (at 60 degrees Celsius and pH 6.2)


organism: Methanosarcina barkeri (strain Fusaro / DSM 804)


substrate_name: formaldehyde


enzyme_display_name: elisabethatriene synthase

organism: Antillogorgia elisabethae


substrate_name: farnesyl diphosphate


substrate_name: geranylgeranyl diphosphate


substrate_name: (2E)-geranyl diphosphate


enzyme_display_name: alpha-bisabolene synthase

organism: Ginkgo biloba

substrate_name: (2E,6E)-farnesyl diphosphate


enzyme_display_name: fusicocca-2,10(14)-diene synthase

organism: Diaporthe amygdali


substrate_name: geranyl diphosphate


enzyme_display_name: epi-cedrol synthase

organism: Artemisia annua


substrate_name: isopentenyl diphosphate


substrate_name: dimethylallyl diphosphate


enzyme_display_name: terpentetriene synthase

organism: Kitasatospora griseola

substrate_name: TDP


substrate_name: trans,trans-Farnesyl diphosphate; Isopentenyl diphosphate


organism: Santalum album


organism: Abies grandis


enzyme_display_name: ent-pimara-9(11),15-diene synthase

organism: Streptomyces sp. (strain KO-3988)

substrate_name: ent-CDP


organism: Hedychium coronarium

substrate_name: Unknown


enzyme_display_name: crotonobetainyl-CoA hydratase

substrate_name: crotonobetainyl-CoA


substrate_name: crotonyl-CoA


enzyme_display_name: short-chain-enoyl-CoA hydratase

organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)


substrate_name: hexenoyl-CoA


organism: Homo sapiens

substrate_name: 17beta-estradiol (2-hydroxylation)


substrate_name: estrone (2-hydroxylation)


enzyme_display_name: (2S)-3-sulfopropanediol dehydratase

organism: Klebsiella oxytoca


enzyme_display_name: alpha-farnesene synthase

organism: Actinidia deliciosa


enzyme_display_name: chondroitin-sulfate-ABC endolyase

organism: Proteus vulgaris

substrate_name: dermatan sulfate


substrate_name: all-trans retinol


enzyme_display_name: beta-farnesene synthase

organism: Mentha x piperita

substrate_name: (2Z,6E)-2-fluorofarnesyl diphosphate


enzyme_display_name: (3S,6E)-nerolidol synthase

organism: Fragaria x ananassa


enzyme_display_name: (3R,6E)-nerolidol synthase

organism: Tripterygium wilfordii


enzyme_display_name: guluronate-specific alginate lyase

organism: Isoptericola halotolerans

substrate_name: alginate


organism: Actinidia chinensis


substrate_name: (2E,6E)-farnesyl diphosphate


enzyme_display_name: epi-isozizaene synthase

organism: Streptomyces coelicolor


substrate_name: (2E)-geranyl diphosphate


organism: Arabidopsis thaliana

substrate_name: farnesyl diphosphate


substrate_name: geranyl diphosphate


organism: Malus domestica

substrate_name: trans,trans-Farnesyl diphosphate


organism: Lavandula angustifolia


organism: Fragaria ananassa

substrate_name: H2O; trans,trans-Farnesyl diphosphate


organism: Zea mays


organism: Hedychium coronarium


organism: Coleus amboinicus


organism: Mentha piperita


substrate_name: magnesium


substrate_name: Manganese


organism: Santalum album


substrate_name: manganese


enzyme_display_name: sabinene-hydrate synthase

organism: Thymus vulgaris


enzyme_display_name: threonine synthase

substrate_name: O-Phospho-L-homoserine


substrate_name: O-phospho-L-homoserine (in presence of 100 uM S-adenosyl-L-methionine)


enzyme_display_name: methylglyoxal synthase

organism: Thermus sp.

substrate_name: dihydroxyacetone phosphate


enzyme_display_name: germacrene-A synthase

organism: Cichorium intybus

substrate_name: 2-trans,6-trans-farnesyl diphosphate


organism: Kitasatospora griseola

substrate_name: terpentedienyl diphosphate


substrate_name: GGDP


enzyme_display_name: abieta-7,13-diene synthase

organism: Abies grandis

substrate_name: copalyl diphosphate


substrate_name: GGPP (in presence of magnesium)


enzyme_display_name: 3-dehydroquinate synthase

organism: Aspergillus nidulans


enzyme_display_name: (-)-beta-caryophyllene synthase

organism: Gossypium hirsutum

substrate_name: (2E,6E)-farnesyl diphosphate


organism: Ocimum kilimandscharicum


enzyme_display_name: (S)-beta-bisabolene synthase


enzyme_display_name: mannuronate-specific alginate lyase

organism: Vibrio sp. NJ-04

substrate_name: alginate


organism: Helianthus annuus

substrate_name: farnesyl diphosphate


organism: Artemisia annua


substrate_name: farnesyl diphosphate (in the presence of 10 mM magnesium and 1 mM manganese)


substrate_name: geranyl diphosphate (in the presence of 10 mM magnesium and 1 mM manganese)


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


substrate_name: (2E)-geranyl diphosphate


organism: Vitis vinifera


substrate_name: Unknown


enzyme_display_name: Bifunctional albaflavenone monooxygenase/terpene synthase

organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

substrate_name: FPP (in the presence of magnesium ions at 30 degrees Celsius and at pH 5.5)


organism: Streptomyces coelicolor


enzyme_display_name: alpha-farnesene synthase

organism: Arabidopsis thaliana


organism: Piper nigrum


organism: Zea mays

substrate_name: farnesyl diphosphate (in the presence of MgCl(2))


enzyme_display_name: (+)-epicubenol synthase

organism: Streptomyces griseus

protein_accession_database: NCBI Protein


enzyme_display_name: beta-selinene cyclase

organism: Citrus x microcarpa


enzyme_display_name: (-)-germacrene D synthase

organism: Solidago canadensis


organism: Coprinopsis cinerea


substrate_name: geranyl diphosphate


enzyme_display_name: (+)-germacrene D synthase

organism: Actinidia deliciosa


enzyme_display_name: alpha-gurjunene synthase


enzyme_display_name: valencene synthase

organism: Callitropsis nootkatensis


enzyme_display_name: (+)-alpha-barbatene synthase


enzyme_display_name: cis-muuroladiene synthase

organism: Mentha x piperita


enzyme_display_name: 5-epiaristolochene synthase

organism: Nicotiana tabacum


organism: Marchantia polymorpha


substrate_name: anilinogeranyl diphosphate


enzyme_display_name: presilphiperfolanol synthase

organism: Botrytis cinerea


substrate_name: trans,trans-Farnesyl diphosphate; H2O


enzyme_display_name: alpha-santalene synthase

organism: Clausena lansium


enzyme_display_name: exo-alpha-bergamotene synthase


organism: Valeriana officinalis


enzyme_display_name: (3S,6E)-nerolidol synthase

substrate_name: geranylgeranyl diphosphate (at pH 7.5)


substrate_name: geranyl diphosphate (at pH 7.5)


enzyme_display_name: beta-chamigrene synthase


enzyme_display_name: 2-methylfumaryl-CoA hydratase

organism: Haloarcula hispanica


substrate_name: (S)-citramalyl-CoA


enzyme_display_name: mannuronate-specific alginate lyase

organism: Saccharophagus degradans

substrate_name: sodium alginate


enzyme_display_name: enoyl-CoA hydratase 2

organism: Aeromonas caviae

substrate_name: crotonyl-CoA


organism: Homo sapiens


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Bacillus anthracis


enzyme_display_name: cyclohexyl-isocyanide hydratase

organism: Pseudomonas fluorescens

substrate_name: 2-naphthyl isocyanide


enzyme_display_name: oligo-alginate lyase

organism: Stenotrophomonas maltophilia


enzyme_display_name: 2-hydroxyisoflavanone dehydratase

organism: Glycine max


enzyme_display_name: 3-dehydroquinate synthase

organism: Pyrococcus furiosus


enzyme_display_name: aldos-2-ulose dehydratase

organism: Phanerodontia chrysosporium

substrate_name: glucosone


substrate_name: ascopyrone M


substrate_name: xylosone


organism: Glycyrrhiza echinata


enzyme_display_name: 3-hydroxypropionyl-CoA dehydratase

organism: Metallosphaera sedula


enzyme_display_name: colneleate synthase

organism: Solanum lycopersicum


organism: Solanum tuberosum


enzyme_display_name: (+)-delta-cadinene synthase

organism: Gossypium arboreum

substrate_name: 2-trans,6-trans-farnesyl diphosphate


enzyme_display_name: 6-pyruvoyltetrahydropterin synthase

substrate_name: 7,8-Dihydroneopterin 3'-triphosphate


enzyme_display_name: methylglyoxal synthase

organism: Escherichia coli

substrate_name: glycerone phosphate


organism: Actinidia chinensis


enzyme_display_name: bile-acid 7alpha-dehydratase

organism: [Clostridium] hylemonae


enzyme_display_name: ectoine synthase

organism: Sphingopyxis alaskensis


organism: Peptacetobacter hiranonis


enzyme_display_name: o-succinylbenzoate synthase


enzyme_display_name: carotenoid 1,2-hydratase

organism: Rubrivivax gelatinosus

substrate_name: spheroidene


substrate_name: Neurosporene


enzyme_display_name: abieta-7,13-diene synthase

organism: Abies grandis

substrate_name: CPP (in presence of magnesium)


enzyme_display_name: S-linalool synthase

organism: Clarkia breweri


enzyme_display_name: isoprene synthase

organism: Populus tremula x Populus tremuloides

substrate_name: dimethylallyl diphosphate


enzyme_display_name: gluconate/galactonate dehydratase

organism: Saccharolobus solfataricus

substrate_name: D-galactonate


substrate_name: D-Gluconate


enzyme_display_name: R-linalool synthase

organism: Lavandula angustifolia

substrate_name: geranyl diphosphate


organism: Thermus sp.

substrate_name: dihydroxyacetone phosphate


organism: Aspergillus nidulans

substrate_name: NAD+


enzyme_display_name: (3S,6E)-nerolidol synthase

substrate_name: (2E,6E)-farnesyl diphosphate


organism: Fragaria ananassa


enzyme_display_name: (S)-beta-bisabolene synthase

organism: Zea mays

substrate_name: farnesyl diphosphate


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


enzyme_display_name: exo-alpha-bergamotene synthase

organism: Santalum spicatum


organism: Santalum austrocaledonicum


organism: Santalum album


enzyme_display_name: zingiberene synthase

organism: Arabidopsis thaliana


enzyme_display_name: beta-santalene synthase


enzyme_display_name: thujopsene synthase


enzyme_display_name: alpha-santalene synthase


organism: Hedychium coronarium

substrate_name: Unknown


substrate_name: (2E)-geranyl diphosphate


enzyme_display_name: trichodiene synthase

organism: Fusarium sporotrichioides


enzyme_display_name: (+)-beta-caryophyllene synthase

organism: Ocimum kilimandscharicum


enzyme_display_name: cis-muuroladiene synthase

organism: Mentha piperita

substrate_name: trans,trans-Farnesyl diphosphate


organism: Piper nigrum


organism: Solanum lycopersicum

substrate_name: neryl diphosphate


organism: Vitis vinifera


enzyme_display_name: alpha-guaiene synthase

organism: Aquilaria crassna


organism: Lavandula angustifolia


enzyme_display_name: cubebol synthase

organism: Coprinopsis cinerea


substrate_name: trans,trans-Farnesyl diphosphate; H2O


enzyme_display_name: cyclohexyl-isocyanide hydratase

organism: Pseudomonas putida

substrate_name: cyclohexyl isocyanide


organism: Thauera aromatica


enzyme_display_name: 5-epi-alpha-selinene synthase

organism: Nostoc sp.


enzyme_display_name: bile-acid 7alpha-dehydratase

organism: Clostridium scindens


organism: Bacillus subtilis (strain 168)

substrate_name: S-methyl-5-thio-D-ribulose 1-phosphate (at 25 degrees Celsius)


enzyme_display_name: acetylene hydratase

organism: Syntrophotalea acetylenica

substrate_name: Acetylene


enzyme_display_name: (-)-alpha-cuprenene synthase


enzyme_display_name: o-succinylbenzoate synthase

organism: Bacillus subtilis


organism: Escherichia coli


organism: Streptomyces griseus


enzyme_display_name: germacrene C synthase

organism: Valeriana officinalis


enzyme_display_name: avermitilol synthase

organism: Streptomyces avermitilis


enzyme_display_name: (-)-delta-cadinene synthase

organism: Streptomyces clavuligerus


enzyme_display_name: labdatriene synthase

organism: Oryza sativa

substrate_name: syn-copalyl diphosphate


enzyme_display_name: carotenoid 1,2-hydratase

organism: Rubrivivax gelatinosus

substrate_name: lycopene


enzyme_display_name: 4-hydroxybutanoyl-CoA dehydratase

organism: Clostridium aminobutyricum


enzyme_display_name: delta-guaiene synthase

organism: Aquilaria crassna


organism: Thiocapsa roseopersicina


enzyme_display_name: 3-dehydroshikimate dehydratase

organism: Neurospora crassa


organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)


organism: Metallosphaera sedula


enzyme_display_name: tetrahymanol synthase

organism: Tetrahymena thermophila

substrate_name: squalene


organism: Arabidopsis thaliana


substrate_name: geranyl diphosphate


enzyme_display_name: L-galactonate dehydratase

organism: Trichoderma reesei

substrate_name: L-galactonate


enzyme_display_name: 2-methylfumaryl-CoA hydratase

organism: Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)

substrate_name: mesaconyl-CoA


enzyme_display_name: versicolorin B synthase

organism: Aspergillus parasiticus

substrate_name: versiconal


enzyme_display_name: (-)-sabinene synthase

organism: Picea sitchensis


enzyme_display_name: alpha-humulene synthase

organism: Gossypium hirsutum

substrate_name: (2E,6E)-farnesyl diphosphate


organism: Methylorubrum extorquens


enzyme_display_name: (+)-car-3-ene synthase

organism: Lavandula x intermedia


organism: Conocephalum conicum


enzyme_display_name: 1,8-cineole synthase

organism: Artemisia annua


enzyme_display_name: pterocarpan synthase

organism: Glycyrrhiza echinata


enzyme_display_name: gamma-curcumene synthase

organism: Zea mays

substrate_name: farnesyl diphosphate (in the presence of 10 mM magnesium and 1 mM manganese)


substrate_name: geranyl diphosphate (in the presence of 10 mM magnesium and 1 mM manganese)


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


enzyme_display_name: (E)-beta-ocimene synthase

substrate_name: (2E)-geranyl diphosphate


organism: Salvia fruticosa


organism: Nicotiana suaveolens


organism: Zingiber zerumbet


enzyme_display_name: 7-epi-sesquithujene synthase


organism: Piper nigrum


enzyme_display_name: (+)-T-muurolol synthase

organism: Streptomyces clavuligerus


organism: Arabidopsis thaliana


organism: Pinus contorta

substrate_name: (3S)-linalyl diphosphate


substrate_name: Geranyl diphosphate


enzyme_display_name: crotonobetainyl-CoA hydratase

organism: Proteus sp. (in: enterobacteria)

substrate_name: crotonyl-CoA


substrate_name: Unknown


organism: Homo sapiens

substrate_name: 17beta-estradiol (2-hydroxylation)


substrate_name: Geranyl diphosphate; H2O


organism: Salvia officinalis


organism: Danio rerio

substrate_name: prostaglandin H2 (at 23 degrees Celsius)


substrate_name: geranyl diphosphate


enzyme_display_name: short-chain-enoyl-CoA hydratase

organism: Metallosphaera sedula


organism: Picea sitchensis


enzyme_display_name: (-)-limonene synthase TPS1, chloroplastic

organism: Cannabis sativa

substrate_name: Geranyl pyrophosphate


organism: Sus scrofa

substrate_name: prostaglandin H2


enzyme_display_name: tetracenomycin F2 cyclase

organism: Streptomyces glaucescens

substrate_name: tetracenomycin F2


enzyme_display_name: terpinolene synthase

substrate_name: neryl diphosphate


substrate_name: (3R)-linalyl diphosphate


enzyme_display_name: gamma-terpinene synthase


organism: Lavandula angustifolia


organism: Citrus x limon


organism: Nicotiana suaveolens


enzyme_display_name: (+)-camphene synthase

organism: Artemisia annua


enzyme_display_name: (-)-camphene synthase


organism: Hedychium coronarium


enzyme_display_name: (+)-sabinene synthase


organism: Camellia sinensis var. sinensis


organism: Origanum vulgare


enzyme_display_name: alpha-terpinene synthase


substrate_name: manganese (in the presence of 10 uM geranyl diphosphate)


substrate_name: magnesium (in the presence of 10 uM geranyl diphosphate)


substrate_name: geranyl diphosphate (in the presence of 0.5 mM manganese)


organism: Zea mays

substrate_name: farnesyl diphosphate


substrate_name: magnesium (in the presence of 10 uM farnesyl diphosphate)


substrate_name: manganese (in the presence of 10 uM farnesyl diphosphate)


enzyme_display_name: (+)-alpha-pinene synthase TPS2, chloroplastic


enzyme_display_name: cis-L-3-hydroxyproline dehydratase

organism: Agrobacterium tumefaciens


organism: Oceanobacillus iheyensis

substrate_name: galactarate


organism: Saccharopolyspora spinosa


enzyme_display_name: L-talarate dehydratase

organism: Salmonella enterica subsp. enterica serovar Typhimurium

substrate_name: L-talarate


enzyme_display_name: (-)-alpha-terpineol synthase

organism: Salvia fruticosa

substrate_name: (2E)-geranyl diphosphate


enzyme_display_name: (-)-alpha-pinene synthase

organism: Salvia officinalis


enzyme_display_name: (-)-beta-pinene synthase

organism: Gossypium hirsutum


substrate_name: (RS)-alpha-terpinyl diphosphate


enzyme_display_name: (+)-beta-pinene synthase


enzyme_display_name: (+)-alpha-pinene synthase


enzyme_display_name: beta-sesquiphellandrene synthase

organism: Persicaria minor

substrate_name: (2E,6E)-farnesyl diphosphate


enzyme_display_name: 2-deoxy-scyllo-inosose synthase

organism: Streptoalloteichus hindustanus

substrate_name: D-glucose 6-phosphate


substrate_name: geranyl diphosphate


organism: Rickettsia endosymbiont of Ixodes scapularis


organism: Niallia circulans


organism: Bacillus circulans

substrate_name: D-Glucose 6-phosphate


organism: Nicotiana suaveolens


organism: Arabidopsis thaliana


organism: Pseudomonas aeruginosa


enzyme_display_name: 2-methylisoborneol synthase

organism: Pseudanabaena limnetica

substrate_name: (E)-2-methylgeranyl diphosphate


organism: Streptomyces coelicolor

substrate_name: Geranyl diphosphate; H2O


organism: Hedychium coronarium

substrate_name: Unknown


enzyme_display_name: guluronate-specific alginate lyase

organism: Flammeovirga sp. NJ-04

substrate_name: alginate


substrate_name: 2-methylneryl diphosphate


enzyme_display_name: 2-methylisocitrate dehydratase

organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

substrate_name: isocitrate


organism: Wenyingzhuangia fucanilytica


organism: Escherichia coli


enzyme_display_name: 1,8-cineole synthase

organism: Salvia officinalis


substrate_name: (3R)-linalyl diphosphate


enzyme_display_name: chondroitin-sulfate-ABC exolyase

organism: Proteus vulgaris

substrate_name: dermatan sulfate


enzyme_display_name: 5-phosphooxy-L-lysine phospho-lyase

organism: Rattus norvegicus


enzyme_display_name: mannuronate-specific alginate lyase


organism: Paenarthrobacter aurescens

substrate_name: inulin


organism: Isoptericola halotolerans


organism: Mus musculus


enzyme_display_name: valerena-4,7(11)-diene synthase

organism: Valeriana officinalis


enzyme_display_name: (+)-epi-alpha-bisabolol synthase

organism: Phyla dulcis


enzyme_display_name: sclareol synthase

organism: Salvia sclarea


organism: Pinus taeda


organism: Streptomyces fradiae


organism: Homo sapiens

substrate_name: H2O; 5-Phosphonooxy-L-lysine


organism: Abies grandis


enzyme_display_name: Delta(6)-protoilludene synthase

organism: Stereum hirsutum (strain FP-91666)


substrate_name: farnesyl diphosphate (FPP)


organism: Microbulbifer sp. 6532A


enzyme_display_name: threonine synthase

organism: Escherichia coli (strain K12)

substrate_name: O-phospho-L-homoserine


organism: Pseudoalteromonas sp.


organism: Methanosarcina acetivorans C2A


organism: Methanocaldococcus jannaschii

substrate_name: D-glyceraldehyde 3-phosphate


organism: Streptomyces sp.

substrate_name: geranylgeranyl diphosphate


enzyme_display_name: demethyl-4-deoxygadusol synthase

organism: Trichormus variabilis

substrate_name: D-sedoheptulose 7-phosphate


enzyme_display_name: 2-epi-valiolone synthase

organism: Stigmatella aurantiaca


enzyme_display_name: (-)-spiroviolene synthase

organism: Streptomyces violens


organism: Nostoc punctiforme (strain ATCC 29133 / PCC 73102)

substrate_name: sedoheptulose 7-phosphate


organism: Mycobacterium tuberculosis


enzyme_display_name: alpha-humulene synthase

organism: Arabidopsis thaliana

substrate_name: farnesyl diphosphate


substrate_name: D-glyceraldehyde


organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)


enzyme_display_name: dolabella-3,7-dien-18-ol synthase


enzyme_display_name: dolathalia-3,7,11-triene synthase


enzyme_display_name: 5-hydroxy-alpha-gurjunene synthase

organism: Marchantia polymorpha

substrate_name: (2E,6E)-farnesyl diphosphate


substrate_name: Geranyl diphosphate


substrate_name: Unknown


organism: Humulus lupulus


organism: Artemisia annua

substrate_name: geranyl diphosphate


enzyme_display_name: (-)-drimenol synthase

organism: Aquimarina spongiae